What kinds of substrates show P-glycoprotein-dependent intestinal absorption? Comparison of verapamil with vinblastine.

Drug metabolism and pharmacokinetics

Volumn 21, Issue 3, 2006, Pages 238-244

  Ogihara, Takuo ^a   Kamiya, Masatsugu ^a   Ozawa, Makoto ^a   Fujita, Takuya ^a   Yamamoto, Akira ^a   Yamashita, Shinji ^a   Ohnishi, Shuhei ^a   Isomura, Yasuo ^a  

^a MOCHIDA PHARMACEUTICAL CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GLYCOPROTEIN P; MANNITOL; MESSENGER RNA; PHENAZONE; TRITIUM; VERAPAMIL; VINBLASTINE;

ANIMAL; AREA UNDER THE CURVE; ARTICLE; CELL STRAIN CACO 2; DRUG EFFECT; DUODENUM; GENE EXPRESSION; GENETICS; HUMAN; ILEUM; INTESTINE ABSORPTION; INTRAVENOUS DRUG ADMINISTRATION; LIVER; METABOLISM; MOUSE; MOUSE MUTANT; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIPYRINE; AREA UNDER CURVE; CACO-2 CELLS; DUODENUM; GENE EXPRESSION; HUMANS; ILEUM; INJECTIONS, INTRAVENOUS; INTESTINAL ABSORPTION; LIVER; MANNITOL; MICE; MICE, KNOCKOUT; P-GLYCOPROTEIN; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRITIUM; VERAPAMIL; VINBLASTINE;

EID: 33749036875     PISSN: 13474367     EISSN: None     Source Type: Journal    
DOI: 10.2133/dmpk.21.238     Document Type: Article

References (0)