Interaction between glutamate signalling and immune attack in damaging oligodendrocytes

Neuron Glia Biology

Volumn 3, Issue 4, 2007, Pages 281-285

  Matute, Carlos ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Complement; Excitotoxicity; Glutamate; Microglia; Oligodendrocytes

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CALCIUM ION; GLUTAMATE RECEPTOR; GLUTAMIC ACID; KAINIC ACID; KAINIC ACID RECEPTOR; MYELIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; REACTIVE OXYGEN METABOLITE;

BRAIN DISEASE; CELL DEATH; CELL ISOLATION; CYTOSOL; DEGENERATIVE DISEASE; DEMYELINATING DISEASE; EXCITOTOXICITY; HOMEOSTASIS; HUMAN; IMMUNOLOGY; INFLAMMATION; MICROGLIA; MULTIPLE SCLEROSIS; NONHUMAN; OLIGODENDROGLIA; OPTIC NERVE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; WHITE MATTER;

EID: 46749128950     PISSN: 1740925X     EISSN: 17410533     Source Type: Journal    
DOI: 10.1017/S1740925X08000033     Document Type: Review

References (44)

1. Alberdi E., Sánchez-Gómez M.V., Torre I., Domercq M., Pérez-Samartín A., Pérez-Cerdá F. et al. (2006) Activation of kainate receptors sensitizes oligodendrocytes to complement attack. Journal of Neuroscience 26, 3220-3228.
2. Appel S.H. and Bonstein M.B. (1964) The application of tissue culture to the study of experimental allergic encephalomyelitis. II. Serum factors responsible for demyelination. Journal of Experimental Medicine 119, 303-312.
3. Anderson C.M. and Nedergaard M. (2006) Emerging challenges of assigning P2X7 receptor function and immunoreactivity in neurons. Trends in Neurosciences 29, 257-262.
4. Back S.A., Craig A., Kayton R.J., Luo N.L., Meshul C.K., Allcock N. et al. (2007) Hypoxia-ischemia preferentially triggers glutamate depletion from oligodendroglia and axons in perinatal cerebral white matter. Journal of Cerebral Blood Flow and Metabolism 27, 334-347.
5. Barnett M.H. and Prineas J.W. (2004) Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Annals of Neurology 55, 458-468.
6. Belachew S. and Gallo V. (2004) Synaptic and extrasynaptic neurotransmitter receptors in glial precursors' quest for identity. Glia 48, 185-196.
7. Danbolt N.C. (2001) Glutamate uptake. Progress in Neurobiology 65, 1-105.
8. Deng W., Wang H., Rosenberg P.A., Volpe J.J. and Jensen F.E. (2004) Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress. Proceedings of the National Academy of Sciences of the U.S.A. 101, 7751-7756.
9. Domercq M., Sánchez-Gómez M.V., Areso P. and Matute C. (1999) Expression of glutamate transporters in rat optic nerve oligodendrocytes. European Journal of Neuroscience 11, 2226-2236.
10. Domercq M., Etxebarria E., Pérez-Samartín A. and Matute C. (2005) Excitotoxic oligodendrocyte death and axonal damage induced by glutamate transporter inhibition. Glia 52, 36-46.
11. Domercq M., Sánchez-Gómez M.V., Sherwin C., Etxebarria E., Fern R. and Matute C. (2007) System xc 2 and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes. Journal of Immunology 178, 6549-6556.
12. Gallo V., Zhou J.M., McBain C.J., Wright P., Knutson P.L. and Armstrong R.C. (1996) Oligodendrocyte progenitor cell proliferation and lineage progression are regulated by glutamate receptor-mediated K+ channel block. Journal of Neuroscience 16, 2659-2670.
13. Huang Y.H. and Bergles D.E. (2004) Glutamate transporters bring competition to the synapse. Current Opinion in Neurobiology 14, 346-352.
14. Kanwar J.R., Kanwar R.K. and Krissansen G.W. (2004) Simultaneous neuroprotection and blockade of inflammation reverses autoimmune encephalomyelitis. Brain 127, 1313-1331.
15. Káradóttir R. and Attwell D. (2007) Neurotransmitter receptors in the life and death of oligodendrocytes. Neuroscience 145, 1426-1438.
16. Karadottir R., Cavelier P., Bergersen L.H. and Attwell D. (2005) NMDA receptors are expressed in oligodendrocytes and activated in ischaemia. Nature 438, 1162-1166.
17. Kettenmann H. and Steinhauser C. (2005) Receptors for neurotransmitters and hormones. In Kettenmann H. and Ransom B.R. (eds) Neuroglia (2nd edn). Oxford University Press, pp. 131-145.
18. Kukley M., Capetillo-Zarate E. and Dietrich D. (2007) Vesicular glutamate release from axons in white matter. Nature Neuroscience 10, 311-320.
19. Li S. and Stys P.K. (2000) Mechanisms of ionotropic glutamate receptor-mediated excitotoxicity in isolated spinal cord white matter. Journal of Neuroscience 20, 1190-1198.
20. Li S., Mealing G.A., Morley P. and Stys P.K. (1999) Novel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport. Journal of Neuroscience 19, RC16.
21. Linington, Morgan B.P., Scolding N.J., Wilkins P., Piddlesden S. and Compston D.A. (1989) The role of complement in the pathogenesis of experimental allergic encephalomyelitis. Brain 112, 895-911.
22. Lucchinetti C., Bruck W., Parisi J., Scheithauer B., Rodriguez M. and Lassmann H. (2000) Heterogeneity of multiple sclerosis lesions, implications for the pathogenesis of demyelination. Annals of Neurology 47, 707-717.
23. Matute C., Sánchez-Gómez M.V., Martínez- Millán L. and Miledi R. (1997) Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes. Proceedings of the National Academy of Sciences of the U.S.A. 94, 8830-8835.
24. Matute C. (2006) Oligodendrocyte NMDA receptors: a novel therapeutic target. Trends in Molecuar Medicine 12, 289-292.
25. Matute C., Domercq M. and Sánchez-Gómez M.V. (2006) Glutamatemediated glial injury: mechanisms and clinical importance. Glia 53, 212-224.
26. Matute C., Alberdi E., Domercq M., Sánchez-Gómez M.V., Pérez-Samartín A., Rodríguez-Antigüedad A. et al. (2007a) Excitotoxic damage to white matter. Journal of Anatomy 210, 693-702.
27. Matute C., Torre I., Pérez-Cerdá F., Pérez-Samartín A., Alberdi E., Etxebarria E. et al. (2007b) P2X(7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes and ameliorates experimental autoimmune encephalomyelitis. Journal of Neuroscience 27, 9525-9533.
28. McDonald J.W., Althomsons S.P., Hyrc K.L., Choi D.W. and Goldberg M.P. (1998) Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity. Nature Medicine 4, 291-297.
29. Mead R.J., Singhrao S.K., Neal J.W., Lassmann H. and Morgan B.P. (2002) The membrane attack complex of complement causes severe demyelination associated with acute axonal injury. Journal of Immunology 168, 458-465.
30. Merrill J.E. and Benveniste E.N. (1996) Cytokines in inflammatory brain lesions: helpful and harmful. Trends in Neurosciences 19, 331-338.
31. Micu I., Jiang Q., Coderre E., Ridsdale A., Zhang L., Woulfe J. et al. (2006) NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature 439, 988-992.
32. Oka A., Belliveau M.J., Rosenberg P.A. and Volpe J.J. (1993) Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention. Journal of Neuroscience 13, 1441-1453.
33. Pitt D., Werner P. and Raine C.S. (2000) Glutamate excitotoxicity in a model of multiple sclerosis. Nature Medicine 6, 67-70.
34. Regan M.R., Huang Y.H., Kim Y.S., Dykes-Hoberg M.I., Jin L., Watkins A.M. et al. (2007) Variations in promoter activity reveal a differential expression and physiology of glutamate transporters by glia in the developing and mature CNS. Journal of Neuroscience 27, 6607-6619.
35. Salter M.G. and Fern R. (2005) NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury. Nature 438, 1167-1171.
36. Sánchez-Gómez M.V. and Matute C. (1999) AMPA and kainate receptors each mediate excitotoxicity in oligodendroglial cultures. Neurobiology of Disease 6, 475-485.
37. Sánchez-Gómez M.V., Alberdi E., Ibarretxe G., Torre I. and Matute C. (2003) Caspase-dependent and caspase-independent oligodendrocyte death mediated by AMPA and kainate receptors. Journal of Neuroscience 23, 9519-9528.
38. Smith T., Groom A., Zhu B. and Turski L. (2000) Autoimmune encephalomyelitis ameliorated by AMPA antagonists. Nature Medicine 6, 62-66.
39. Takahashi J.L., Giuliani F., Power C., Imai Y. and Yong V.W. (2003) Interleukin-1beta promotes oligodendrocyte death through glutamate excitotoxicity. Annals of Neurology 53, 588-595.
40. Taylor D.L., Jones F., Kubota E.S. and Pocock J.M. (2005) Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand. Journal of Neuroscience 25, 2952-2964.
41. Xiong Z.Q. and McNamara J.O. (2002) Fleeting activation of ionotropic glutamate receptors sensitizes cortical neurons to complement attack. Neuron 36, 363-374.
42. Yoshioka A., Hardy M., Younkin D.P., Grinspan J.B., Stern J.L. and Pleasure D. (1995) Alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA) receptors mediate excitotoxicity in the oligodendroglial lineage. Journal of Neurochemistry 64, 2442-2448.
43. Zhang K. and Sejnowski T.J. (2000) A universal scaling law between gray matter and white matter of cerebral cortex. Proceedings of the National Academy of Sciences of the U.S.A. 97, 5621-5626.
44. Ziskin J.L., Nishiyama A., Rubio M., Fukaya M. and Bergles D.E. (2007) Vesicular release of glutamate from unmyelinated axons in white matter. Nature Neuroscience 10, 321-330.