The role of complement in the pathogenesis of experimental allergic encephalomyelitis

Brain

Volumn 112, Issue 4, 1989, Pages 895-911

  Linington, C ^a   Morgan, B P ^a   Scolding, N J ^a   Wilkins, P ^a   Piddlesden, S ^a   Compston, D A S ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; MYELIN BASIC PROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL CULTURE; DEMYELINATION; HISTOLOGY; INFLAMMATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT;

ANIMAL; ANTIBODIES, MONOCLONAL; CELL SURVIVAL; COBRA VENOMS; COMPLEMENT; COMPLEMENT INACTIVATORS; ENCEPHALOMYELITIS, EXPERIMENTAL AUTOIMMUNE; IMMUNIZATION; IMMUNIZATION, PASSIVE; MYELIN BASIC PROTEINS; MYELIN SHEATH; OLIGODENDROGLIA; RATS; RATS, INBRED LEW; SUPPORT, NON-U.S. GOV'T;

EID: 0024334648     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/112.4.895     Document Type: Article

References (51)

1. Banik NL, McAlhaney WW, Hogan EL (1985) Calcium-stimulated proteolysis in myelin: evidence for a Ca2-activated neutral proteinase associated with purified myelin of rat CNS. Journal of Neurochemistry, 45, 581-588
2. Ben-Nun A, Wekerle H, Cohen IR (1981) The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. European Journal of Immunology, 11, 195-199
3. Bradbury K, Aparicio SR, Sumner DW, Bird CC (1984) Role of complement in demyelination in vitro by multiple sclerosis serum and other neurological disease sera. Journal of the Neurological Sciences, 65, 293-305
4. Brosnan CF, Stoner GL, Bloom BR, Wisniewski HM (1977) Studies on demyelination by activated lymphocytes in the rabbit eye. II. Antibody-dependent cell-mediated demyelination. Journal of Immunology, 118, 2103-2110
5. Brosnan CF, Bornstein MB, Bloom BR (1981) The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis. Journal of Immunology, 126, 614-620
6. Brosnan CF, Traugott U, Raine CS (1983) Analysis of humoral and cellular events and the role of lipid haptens during CNS demyelination. Acta Neuropathologica, Berlin, Supplement 9, 5970
7. Cammer W, Brosnan CF, Basile C, Bloom BR, Norton WT (1986) Complement potentiates the degradation of myelin proteins by plasmin: implications for a mechanism of inflammatory demyelination. Brain Research, Amsterdam, 364, 91-101
8. Campbell AK (1987) Intracellular calcium: friend or foe? Clinical Science, 72, 1-10
9. Carney DF, Koski CL, Shin ML (1985) Elimination of terminal complement intermediates from the plasma membrane of nucleated cells: the rate of disappearance differs for cells carrying C5b-7 or C5b-8 or a mixture of C5b-8 with a limited number of C5b-9. Journal of Immunology, 134, 1804-1809
10. Compston DAS, Morgan BP, Campbell AK (1987) Cerebrospinal fluid complement components in multiple sclerosis. In: Cellular and Humoral Immunological Components of Cerebrospinal Fluid in Multiple Sclerosis. Edited by A. Lowenthal and J. Raus. New York and London: Plenum Press, pp. 201-209
11. Dubois-Dalcq M, Niedieck B, Buyse M (1970) Action of anti-cerebroside sera on myelinated nervous tissue cultures. Pathologia Europaea, 5, 331-347
12. Goldmuntz EA, Brosnan CF, Norton WT (1986) Prazosin treatment suppresses increased vascular permeability in both acute and passively transferred experimental autoimmune encephalomyelitis in the Lewis rat. Journal of Immunology, 137, 3444-3450
13. Hetland G, Johnson E, Falk RJ, Eskeland T (1986) Synthesis of complement components C5, C6, C7, C8 and C9 in vitro by human monocytes and assembly of the terminal complement complex. Scandinavian Journal of Immunology, 24, 421-428
14. Hirano A, Dembitzer HM, Becker NH, Levine S, Zimmerman HM (1970) Fine structural alterations of the blood-brain barrier in experimental allergic encephalomyelitis. Journal of Neuropathology and Experimental Neurology, 29, 432-440
15. Jose PJ (1987) Complement-derived peptide mediators of inflammation. British Medical Bulletin, 43, 336-349
16. Juhler M, Barry DI, Offner H, Konat G, Klinken L, Paulson OB (1984) Blood-brain and blood- spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat. Brain Research, Amsterdam, 302, 347-355
17. Kerlero de Rosbo N, Bernard CCA, Simmons RD, Carnegie PR (1985) Concomitant detection of changes in myelin basic protein and permeability of blood-spinal cord barrier in acute experimental autoimmune encephalomyelitis by electroimmunoblotting. Journal of Neuroimmunology, 9, 349-361
18. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, London, 227, 680-685
19. Lassmann H, Kitz K, Wisniewski HM (1981) In vivo effect of sera from animals with chronic relapsing experimental allergic encephalomyelitis on central and peripheral myelin. Acta Neuropathologica, Berlin, 55, 297-306
20. Lassmann H, Brunner C, Bradl M, Linington C (1988) Experimental allergic encephalomyelitis: the balance between encephalitogenic T lymphocytes and demyelinating antibodies determines size and structure of demyelinated lesions. Acta Neuropathologica, Berlin, 75, 566-576
21. Lebar R, Boutry J-M, Vincent C, Robineaux R, Voisin GA (1976) Studies on autoimmune encephalomyelitis in the guinea pig. II. An in vitro investigation on the nature, properties, and specificity of the serum-demyelinating factor. Journal of Immunology, 116, 1439-1446
22. Lévi-Strauss M, Mallat M (1987) Primary cultures of murine astrocytes produce C3 and factor B, two components of the alternative pathway of complement activation. Journal of Immunology, 139, 2361-2366
23. Levine S, Cochrane CG, Carpenter CB, Behan PO (1971) Allergic encephalomyelitis: effect of complement depletion with cobra venom. Proceedings of the Society for Experimental Biology and Medicine, 138, 285-289
24. Linington C, Webb M, Woodhams PL (1984) A novel myelin-associated glycoprotein defined by a mouse monoclonal antibody. Journal of Neuroimmunology, 6, 387-396
25. Linington C, Lassmann H (1987) Antibody responses in chronic relapsing experimental allergic encephalomyelitis: correlation of serum demyelinating activity with antibody titre to the myelin/oligodendrocyte glycoprotein (MOG). Journal of Neuroimmunology, 17, 61-69
26. Linington C, Bradl M, Lassmann H, Brunner C, Vass K (1988) Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. American Journal of Pathology, 130, 443-454
27. Liu WT, Vanguri P, Shin ML (1983) Studies on demyelination in vitro: the requirement of membrane attack components of the complement system. Journal of Immunology, 131, 778-782
28. Lumsden CE (1971) The immunogenesis of the multiple sclerosis plaque. Brain Research, Amsterdam, 28, 365-390
29. Morariu MA, Dalmasso AP (1978) Experimental allergic encephalomyelitis in cobra venom factor- treated and C4-deficient guinea pigs. Annals of Neurology, 4, 427-430
30. Morgan BP, Campbell AK, Compston DAS (1984u) Terminal component of complement (C9) in cerebrospinal fluid of patients with multiple sclerosis. Lancet, 2, 251-254
31. Morgan BP, Campbell AK, Luzio JP, Hallett MB (19846) Recovery of Polymorphonuclear leucocytes from complement attack. Biochemical Society Transactions, 12, 779-780
32. Morgan BP, Dankert JR, Esser AF (1987) Recovery of human neutrophils from complement attack: removal of the membrane attack complex by endocytosis and exocytosis. Journal of Immunology, 138, 246-253
33. Ortiz-Ortiz L, Weigle WO (1976) Cellular events in the induction of experimental allergic encephalomyelitis in rats. Journal of Experimental Medicine, 144, 604-616
34. Pabst H, Day NK, Gewurz H, Good RA (1971) Prevention of experimental allergic encephalomyelitis with cobra venom factor. Proceedings of the Society for Experimental Biology and Medicine, 136, 555-560
35. Parham P (1986) Preparation and purification of active fragments from mouse monoclonal antibodies. In: Handbook of Experimental Immunology, Volume 1. Edited by D. M. Weir. Oxford: Blackwell, pp. 14.1-14.23
36. Raff MC, Miller RH, Noble M (1983) A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature, London, 303, 390-396
37. Raine CS, Johnson AB, Marcus DM, Suzuki A, Bornstein MB (1981) Demyelination in vitro: absorption studies demonstrate that galactocerebroside is a major target. Journal of the Neurological Sciences, 52, 117-131
38. Ramm LE, Whitlow MB, Koski CL, Shin ML, Mayer MM (1983) Elimination of complement channels from the plasma membranes of U937, a nucleated mammalian cell line: temperature dependence of the elimination rate. Journal of Immtmology, 131, 1411-1415
39. Ranscht B, Clapshaw PA, Price J, Noble M, Seifert W (1982) Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside. Proceedings of the National Academy of Sciences of the USA, 79, 2709-2713
40. Rother K, Rother U, Hansch G (1985) The role of complement in inflammation. Pathology, Research and Practice, 180, 117-124
41. Sanders ME, Koskj CL, Robbins D, Shin ML, Frank MM, Joiner KA (1986) Activated terminal complement in cerebrospinal fluid in Guillain-Barre syndrome and multiple sclerosis. Journal of Immunology, 136, 4456-4459
42. Schlaepfer WW (1977) Vesicular disruption of myelin stimulated by exposure of nerve to calcium ionophore. Nature, London, 265, 734-736
43. Schluesener HJ, Sobel RA, Linington C, Weiner HL (1987) A monoclonal antibody against a myelin oligodendrocyte glycoprotein induces relapses and demyelination in central nervous system autoimmune disease. Journal of Immunology, 139, 4016-4021
44. Schwerer B, Krrz TC, Lassmann H, Bernheimer H (1984) Serum antibodies against glycosphingo- lipids in chronic relapsing experimental allergic encephalomyelitis: demonstration by ELISA and relation to serum in vivo demyelinating activity. Journal of_Neuro immunology, 7, 107-119
45. Sedgwick J, Brostoff S, Mason D (1987) Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction: severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system. Journal of Experimental Medicine, 165, 1058-1075
46. Seil FJ, Falk GA, Kies MW, Alvord EC (1968) The in vitro demyelinating activity of sera from guinea pigs sensitized with whole CNS and with purified encephalitogen. Experimental Neurology, 22, 545-555
47. Shirazi Y, Imagawa DK, Shin ML (1987) Release of leukotriene B4 from sublethally injured oligodendrocytes by terminal complement complexes. Journal of Neurochemistry, 48, 271-278
48. Silverman BA, Carney DF, Johnston CA, Vanguri P, Shin ML (1984) Isolation of membrane attack complex of complement from myelin membranes treated with serum complement. Journal of Neurochemistry, 42, 1024-1029
49. Vanguri P, Koski CL, Silverman B, Shin ML (1982) Complement activation by isolated myelin: activation of the classical pathway in the absence of myelin-specific antibodies. Proceedings of the National Academy of Sciences of the USA, 79, 3290-3294
50. Vogel C-W, MOller-Eberhard HJ (1984) Cobra venom factor: improved method for purification and biochemical characterization. Journal of Immunological Methods, 73, 203-220
51. Wekerle H, Linington C, Lassmann H, Meyermann R (1986) Cellular immune reactivity within the CNS. Trends in Neurosciences, 9, 271-277