Quaternary protein mimetics of gp41 elicit neutralizing antibodies against HIV fusion-active intermediate state

Biopolymers - Peptide Science Section

Volumn 90, Issue 3, 2008, Pages 320-329

  Sadler, Kristen ^a   Zhang, Ying ^b,d   Xu, Jiaxi ^b,e   Tam, James P ^a,c  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d Guangzhou South China Biochip Research Center at Guangzhou   (United States)

^e Peking University   (China)

Author keywords

HIV; Neutralizing antibodies; Quaternary protein mimetics

Indexed keywords

AMINES; ANTIBODIES; BIOMIMETICS; MONOMERS; PEPTIDES; PROTEINS;

CHEMOSELECTIVE LIGATIONS; CONFORMATIONAL STABILITIES; HELICAL DOMAINS; HIV; HIV VACCINE; HUMAN IMMUNODEFICIENCY VIRUS TYPE-1; INTERMEDIATE STATES; MIMETICS; NEUTRALIZING ANTIBODIES; PROTEIN MIMETICS; QUATERNARY PROTEIN MIMETICS; QUATERNARY STRUCTURES; VACCINE DESIGN; VIRAL ENVELOPE PROTEINS; VIRAL INFECTIVITY; WITH OR WITHOUT;

VACCINES;

ANTIRETROVIRUS AGENT; GLYCOPROTEIN GP 160; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MONOMER; NEUTRALIZING ANTIBODY; RECOMBINANT GLYCOPROTEIN GP 41; UNCLASSIFIED DRUG; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; RECOMBINANT PROTEIN;

ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; COVALENT BOND; DRUG DESIGN; FEMALE; GUINEA PIG; HELPER CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOPRECIPITATION; NONHUMAN; PROTEIN DOMAIN; PROTEIN QUATERNARY STRUCTURE; PROTEIN SYNTHESIS; TEMPERATURE SENSITIVITY; VACCINE PRODUCTION; VIRION; VIRUS INFECTIVITY; VIRUS STRAIN; ANIMAL; BIOMIMETICS; BLOOD; CELL FUSION; CHEMISTRY; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; METHODOLOGY; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANIMALS; BIOMIMETICS; CELL FUSION; FEMALE; GUINEA PIGS; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP160; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; NEUTRALIZATION TESTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; VIRION;

EID: 46749093878     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20979     Document Type: Article

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