메뉴 건너뛰기




Volumn 10, Issue 6, 1996, Pages 587-593

Restricted antigenic variability of the epitope recognized by the neutralizing gp41 antibody 2F5

Author keywords

Escape variants; Heterogeneity; HIV 1; Human monoclonal antibody; Neutralization

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 41; HUMAN MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

EID: 9344268284     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199606000-00003     Document Type: Article
Times cited : (150)

References (32)
  • 1
    • 0025016076 scopus 로고
    • High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates
    • Daar ES, Li XL, Moudgil T, Ho DD: High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates. Proc Natl Acad Sci USA 1990, 87:6574-6578.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6574-6578
    • Daar, E.S.1    Li, X.L.2    Moudgil, T.3    Ho, D.D.4
  • 2
    • 0028917784 scopus 로고
    • Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120
    • Moore JP, Cao Y, Qing L, et al.: Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120. J Virol 1995, 69:101-109.
    • (1995) J Virol , vol.69 , pp. 101-109
    • Moore, J.P.1    Cao, Y.2    Qing, L.3
  • 4
    • 0037551476 scopus 로고
    • Genomic diversity of the acquired immune deficiency syndrome virus HTLV-III: Different viruses exhibit greatest divergence in their envelope genes
    • Hahn BH, Gonda MA, Shaw GM, et al.: Genomic diversity of the acquired immune deficiency syndrome virus HTLV-III: different viruses exhibit greatest divergence in their envelope genes. Proc Natl Acad Sci USA 1985, 82:4813-4817.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 4813-4817
    • Hahn, B.H.1    Gonda, M.A.2    Shaw, G.M.3
  • 5
    • 0023107134 scopus 로고
    • Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: Prediction of antigenic epitopes in conserved and variable regions
    • Modrow S, Hahn BH, Shaw GM, Gallo RC, Wong-Staal F, Wo H: Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions. J Virol 1987, 61:570-578.
    • (1987) J Virol , vol.61 , pp. 570-578
    • Modrow, S.1    Hahn, B.H.2    Shaw, G.M.3    Gallo, R.C.4    Wong-Staal, F.5    Wo, H.6
  • 6
    • 0028865465 scopus 로고
    • Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG
    • Trkola A, Pomales AP, Yuan H, et al.: Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG. J Virol 1995, 69:6609-6617.
    • (1995) J Virol , vol.69 , pp. 6609-6617
    • Trkola, A.1    Pomales, A.P.2    Yuan, H.3
  • 7
    • 0027378573 scopus 로고
    • A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
    • Muster T, Steindl F, Purtscher M, et al.: A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J Virol 1993, 67:6642-6647.
    • (1993) J Virol , vol.67 , pp. 6642-6647
    • Muster, T.1    Steindl, F.2    Purtscher, M.3
  • 8
    • 0028593629 scopus 로고
    • A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1
    • Purtscher M, Trkola A, Gruber G, et al.: A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 1994, 10:1651-1658.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 1651-1658
    • Purtscher, M.1    Trkola, A.2    Gruber, G.3
  • 9
    • 0028208268 scopus 로고
    • Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody
    • Conley AJ, Kessler II JA, Boots LJ, et al.: Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody. Proc Natl Acad Sci USA 1994, 91:3348-3352.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3348-3352
    • Conley, A.J.1    Kessler II, J.A.2    Boots, L.J.3
  • 10
    • 0000815606 scopus 로고
    • Human monoclonal antibodies against gp41 and gp120 as potential agent for passive immunization
    • Buchacher A, Predl R, Tauer C, et al.: Human monoclonal antibodies against gp41 and gp120 as potential agent for passive immunization. Vaccines 1992, 92:191-195.
    • (1992) Vaccines , vol.92 , pp. 191-195
    • Buchacher, A.1    Predl, R.2    Tauer, C.3
  • 11
    • 0028155283 scopus 로고
    • Electrofusion and EBV-transformation for PBL-immortalization: Generation of human monoclonal antibodies against HIV-1 proteins
    • Buchacher A, Predl R, Strutzenberger K, et al.: Electrofusion and EBV-transformation for PBL-immortalization: generation of human monoclonal antibodies against HIV-1 proteins. AIDS Res Hum Retroviruses 1994, 10:359-369.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 359-369
    • Buchacher, A.1    Predl, R.2    Strutzenberger, K.3
  • 12
    • 0028812047 scopus 로고
    • Interaction between a Fab fragment against gp41 of human immunodeficiency virus 1 and its peptide epitope: Characterization using a peptide epitope library and molecular modeling
    • Stigler R-D, Rüker F, Katinger D, et al.: Interaction between a Fab fragment against gp41 of human immunodeficiency virus 1 and its peptide epitope: characterization using a peptide epitope library and molecular modeling. Protein Engineering 1995, 8:471-479.
    • (1995) Protein Engineering , vol.8 , pp. 471-479
    • Stigler, R.-D.1    Rüker, F.2    Katinger, D.3
  • 13
    • 0023735501 scopus 로고
    • Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines
    • Chaffee S, Leeds JM, Matthews TJ, et al.: Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines. J Exp Med 1988, 168:605-621.
    • (1988) J Exp Med , vol.168 , pp. 605-621
    • Chaffee, S.1    Leeds, J.M.2    Matthews, T.J.3
  • 14
    • 0021237243 scopus 로고
    • Detection, isolation and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS
    • Popovic M, Sarngadharan MG, Read E, Gallo RC: Detection, isolation and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 1984, 224:497-500.
    • (1984) Science , vol.224 , pp. 497-500
    • Popovic, M.1    Sarngadharan, M.G.2    Read, E.3    Gallo, R.C.4
  • 15
    • 0026028914 scopus 로고
    • Biological characterization of infectious molecular clones derived from a human immunodeficiency virus type-1 isolate with rapid/high replicative capacity
    • Fredriksson R, Stalhanske P, vonGegerfelt A, et al.: Biological characterization of infectious molecular clones derived from a human immunodeficiency virus type-1 isolate with rapid/high replicative capacity. Virology 1991, 181:55-61.
    • (1991) Virology , vol.181 , pp. 55-61
    • Fredriksson, R.1    Stalhanske, P.2    VonGegerfelt, A.3
  • 16
    • 0028148319 scopus 로고
    • The World Health Organization Global Programme on AIDS proposal for standardization of HIV sequence nomenclature
    • Korber BTM, Osmanov S, Esparza J, Myers G, and the WHO Network tor HIV Isolation and Characterization: The World Health Organization Global Programme on AIDS proposal for standardization of HIV sequence nomenclature. AIDS Res Hum Retroviruses 1994, 10:1355-1358.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 1355-1358
    • Korber, B.T.M.1    Osmanov, S.2    Esparza, J.3    Myers, G.4
  • 17
    • 0027967560 scopus 로고
    • HIV-1 variation in WHO-sponsored vaccine-evaluation sites: Genetic screening, sequence analysis and preliminary biological characterization of selected viral strains
    • WHO Network for HIV Isolation and Characterization: HIV-1 variation in WHO-sponsored vaccine-evaluation sites: genetic screening, sequence analysis and preliminary biological characterization of selected viral strains. AIDS Res Hum Retroviruses 1994, 10:1327-1344.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 1327-1344
  • 18
    • 33745158157 scopus 로고
    • A simple method of estimating fifty per cent endpoints
    • Reed LJ, Muench H: A simple method of estimating fifty per cent endpoints. Am J Hyg 1938, 27:493-497.
    • (1938) Am J Hyg , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 19
    • 0029137641 scopus 로고
    • Coat protein gene sequence of an Austrian isolate of grapevine fanleaf virus
    • Brandt S, Ibl M, Himmler G: Coat protein gene sequence of an Austrian isolate of grapevine fanleaf virus. Arch Virol 1995, 140:157-164.
    • (1995) Arch Virol , vol.140 , pp. 157-164
    • Brandt, S.1    Ibl, M.2    Himmler, G.3
  • 20
    • 0026656122 scopus 로고
    • Spot-synthesis: An easy technique for the positionally addressable, parallel chemical synthesis on a membrane support
    • Frank R: Spot-synthesis: an easy technique for the positionally addressable, parallel chemical synthesis on a membrane support. Tetrahedron 1992, 48:9217-9232
    • (1992) Tetrahedron , vol.48 , pp. 9217-9232
    • Frank, R.1
  • 21
    • 9044241681 scopus 로고    scopus 로고
    • Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
    • Trkola A, Purtscher M, Muster T, et al.: Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1. J Virol 1996, 70:1100-1108.
    • (1996) J Virol , vol.70 , pp. 1100-1108
    • Trkola, A.1    Purtscher, M.2    Muster, T.3
  • 22
    • 0028277886 scopus 로고
    • Development of the antigp120 antibody response during seroconversion to human immunodeficiency virus type 1
    • Moore JP, Cao Y, Ho DD, Koup RA: Development of the antigp120 antibody response during seroconversion to human immunodeficiency virus type 1. J Virol 1994, 68:5142-5155.
    • (1994) J Virol , vol.68 , pp. 5142-5155
    • Moore, J.P.1    Cao, Y.2    Ho, D.D.3    Koup, R.A.4
  • 23
    • 0028670687 scopus 로고
    • Analysis of B cell repertoire specific to the neutralizing epitopes of glycoprotein 120 in HIV-infected individuals
    • Hariharan K, Nara PL, Shabazz LA, McCutchan JA, Kang C-Y: Analysis of B cell repertoire specific to the neutralizing epitopes of glycoprotein 120 in HIV-infected individuals. AIDS Res Hum Retroviruses 1994, 10:1629-1638.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 1629-1638
    • Hariharan, K.1    Nara, P.L.2    Shabazz, L.A.3    McCutchan, J.A.4    Kang, C.-Y.5
  • 24
    • 0028801450 scopus 로고
    • Epitope exposure on functional, oligomeric HIV-1 gp41 molecules
    • Sattentau QJ, Zolla-Pazner S, Poignard P: Epitope exposure on functional, oligomeric HIV-1 gp41 molecules. Virology 1995, 206:713-717.
    • (1995) Virology , vol.206 , pp. 713-717
    • Sattentau, Q.J.1    Zolla-Pazner, S.2    Poignard, P.3
  • 25
    • 0029040825 scopus 로고
    • Multifaceted consequences of anti-gp41 monoclonal antibody 2F5 binding to HIV-1 virions
    • Neurath AR, Strick N, Lin K, Jiang S: Multifaceted consequences of anti-gp41 monoclonal antibody 2F5 binding to HIV-1 virions. AIDS Res Hum Retroviruses 1995, 11:687-696.
    • (1995) AIDS Res Hum Retroviruses , vol.11 , pp. 687-696
    • Neurath, A.R.1    Strick, N.2    Lin, K.3    Jiang, S.4
  • 26
    • 0025267919 scopus 로고
    • Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera
    • Albert J, Abrahamsson B, Nagy K, et al.: Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera. AIDS 1990, 4:107-112.
    • (1990) AIDS , vol.4 , pp. 107-112
    • Albert, J.1    Abrahamsson, B.2    Nagy, K.3
  • 27
    • 0027229359 scopus 로고
    • Neutralizing antibody response during human immunodeficiency virus type 1 infection: Type and group specificity and viral escape
    • Arendrup M, Sönnerborg A, Svennerholm B, et al.: Neutralizing antibody response during human immunodeficiency virus type 1 infection: type and group specificity and viral escape. J Gen Virol 1993, 74:855-863.
    • (1993) J Gen Virol , vol.74 , pp. 855-863
    • Arendrup, M.1    Sönnerborg, A.2    Svennerholm, B.3
  • 28
    • 0024040544 scopus 로고
    • Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene
    • Reitz MS Jr, Wilson C, Gallo RC, Robert-Guroff M: Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene. Cell 1988, 54:57-63.
    • (1988) Cell , vol.54 , pp. 57-63
    • Reitz Jr., M.S.1    Wilson, C.2    Gallo, R.C.3    Robert-Guroff, M.4
  • 29
    • 0025225306 scopus 로고
    • Generation of neutralization-resistant HIV-1 in vitro due to amino acid interchanges of third hypervariable env region
    • Masuda T, Matsushita S, Kuroda MJ, et al.: Generation of neutralization-resistant HIV-1 in vitro due to amino acid interchanges of third hypervariable env region. J Immunol 1990, 145:3240-3246.
    • (1990) J Immunol , vol.145 , pp. 3240-3246
    • Masuda, T.1    Matsushita, S.2    Kuroda, M.J.3
  • 31
    • 0025362335 scopus 로고
    • Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type-1-IIIb infection of chimpanzees
    • Nara PL, Smit L, Dunlop N, et al.: Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type-1-IIIb infection of chimpanzees. J Virol 1990, 64:3779-3791.
    • (1990) J Virol , vol.64 , pp. 3779-3791
    • Nara, P.L.1    Smit, L.2    Dunlop, N.3
  • 32
    • 0028235930 scopus 로고
    • Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS
    • Muster T, Guinea R, Trkola A, et al.: Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS. J Virol 1994, 68:4031-4034.
    • (1994) J Virol , vol.68 , pp. 4031-4034
    • Muster, T.1    Guinea, R.2    Trkola, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.