Cytosolic accumulation of γH2AX is associated with tropomyosin-related kinase A-induced cell death in U2OS cells

Experimental and Molecular Medicine

Volumn 40, Issue 3, 2008, Pages 276-285

  Eun, Joo Jung ^a   Choong, Won Kim ^a   Deok, Ryong Kim ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

Author keywords

Cell death; DNA damage; H2AFX protein, human; JNK mitogen activated protein kinases; Receptor, trkA

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; DNA; DOXORUBICIN; HISTONE H2AX; K 252A; NERVE GROWTH FACTOR; PROTEIN P21; PROTEIN P53; PROTEIN TYROSINE KINASE A; TETRACYCLINE; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; CARBAZOLE DERIVATIVE; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; H2AFX PROTEIN, HUMAN; HISTONE; INDOLE ALKALOID; K 252; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL DEATH; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; DNA DAMAGE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; APOPTOSIS; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; TUMOR CELL LINE; ULTRASTRUCTURE;

ANTHRACENES; APOPTOSIS; CARBAZOLES; CELL CYCLE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOSOL; DNA DAMAGE; DOXORUBICIN; HISTONES; HUMANS; INDOLE ALKALOIDS; MAP KINASE KINASE 4; NERVE GROWTH FACTOR; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTOR, TRKA; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 46449102968     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2008.40.3.276     Document Type: Article

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