-
2
-
-
0038242819
-
TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
-
Du K, Herzig S, Kulkami RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science. 2003;300: 1574-1577.
-
(2003)
Science
, vol.300
, pp. 1574-1577
-
-
Du, K.1
Herzig, S.2
Kulkami, R.N.3
Montminy, M.4
-
3
-
-
2442701392
-
PGC-1 promotes insulin resistance in liver through PPAR-a-dependent induction of TRB-3
-
Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-a-dependent induction of TRB-3. Nat Med. 2004;10: 530-534.
-
(2004)
Nat Med
, vol.10
, pp. 530-534
-
-
Koo, S.H.1
Satoh, H.2
Herzig, S.3
Lee, C.H.4
Hedrick, S.5
Kulkarni, R.6
Evans, R.M.7
Olefsky, J.8
Montminy, M.9
-
4
-
-
33744955437
-
Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane: Role of TRB3 in inhibition of Akt/protein kinase B activation
-
He L, Simmen FA, Mehendale HM, Ronis MJJ, Badger TM. Chronic ethanol intake impairs insulin signaling in rats by disrupting Akt association with the cell membrane: role of TRB3 in inhibition of Akt/protein kinase B activation. J Biol Chem. 2006;281:11126-11134.
-
(2006)
J Biol Chem
, vol.281
, pp. 11126-11134
-
-
He, L.1
Simmen, F.A.2
Mehendale, H.M.3
Ronis, M.J.J.4
Badger, T.M.5
-
5
-
-
24144466446
-
The functional Q84R polymorphism of mammalian, tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy
-
Prudente S, Hribal ML, Flex E, Turchi F, Morini E, De Cosmo S, Bacci S, Tassi V, Cardellini M, Lauro R, Sesti G, Dallapiccola B, Trischitta V. The functional Q84R polymorphism of mammalian, tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy. Diabetes. 2005;54:2807-2811.
-
(2005)
Diabetes
, vol.54
, pp. 2807-2811
-
-
Prudente, S.1
Hribal, M.L.2
Flex, E.3
Turchi, F.4
Morini, E.5
De Cosmo, S.6
Bacci, S.7
Tassi, V.8
Cardellini, M.9
Lauro, R.10
Sesti, G.11
Dallapiccola, B.12
Trischitta, V.13
-
6
-
-
46249084940
-
TRIB3 R84 variant is associated with impaired insulin-mediated nitric oxide production in human endothelial cells
-
Andreozzi F, Formoso G, Prudente S, Hribal ML, Pandolfi A, Bellacchio E, Di Silvestre S, Trischitta V, Consoli A, Sesti G. TRIB3 R84 variant is associated with impaired insulin-mediated nitric oxide production in human endothelial cells. Arterioscler Thromb Vasc Biol. 2008;28: 1355-1360.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1355-1360
-
-
Andreozzi, F.1
Formoso, G.2
Prudente, S.3
Hribal, M.L.4
Pandolfi, A.5
Bellacchio, E.6
Di Silvestre, S.7
Trischitta, V.8
Consoli, A.9
Sesti, G.10
-
7
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein, kinase Akt
-
Fulton D, Gratton J-P, Mccabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Regulation of endothelium-derived nitric oxide production by the protein, kinase Akt. Nature. 1999;399: 597-601.
-
(1999)
Nature
, vol.399
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.-P.2
Mccabe, T.J.3
Fontana, J.4
Fujio, Y.5
Walsh, K.6
Franke, T.F.7
Papapetropoulos, A.8
Sessa, W.C.9
-
8
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature. 1999;399:601-605.
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
10
-
-
0035947574
-
Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein, kinase
-
Michell BJ, Chen Z, Tiganis T, Stapleton D, Katsis F, Power DA, Sim AT, Kemp BE. Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein, kinase. J Biol Chem. 2001;276:17625-17628.
-
(2001)
J Biol Chem
, vol.276
, pp. 17625-17628
-
-
Michell, B.J.1
Chen, Z.2
Tiganis, T.3
Stapleton, D.4
Katsis, F.5
Power, D.A.6
Sim, A.T.7
Kemp, B.E.8
-
11
-
-
0028065421
-
Insulin blunts sympathetic vasoconstriction through the alpha 2- adrenergic pathway in. humans
-
Lembo G, Iaccarino G, Rendina V, Volpe M, Trimarco B. Insulin blunts sympathetic vasoconstriction through the alpha 2- adrenergic pathway in. humans. Hypertension. 1994;24:429-438.
-
(1994)
Hypertension
, vol.24
, pp. 429-438
-
-
Lembo, G.1
Iaccarino, G.2
Rendina, V.3
Volpe, M.4
Trimarco, B.5
-
12
-
-
0031867143
-
Insulin, and insulin-like growth factor-I cause coronary vasorelaxation in vitro
-
Hasdai D, Rizza RA, Holmes DR Jr, Richardson DM, Cohen P, Lerman A. Insulin, and insulin-like growth factor-I cause coronary vasorelaxation in vitro. Hypertension. 1998;32:228.
-
(1998)
Hypertension
, vol.32
, pp. 228
-
-
Hasdai, D.1
Rizza, R.A.2
Holmes Jr, D.R.3
Richardson, D.M.4
Cohen, P.5
Lerman, A.6
-
14
-
-
0029744981
-
Role of nitric oxide, adenosine, and ATP-sensitive potassium channels in insulin-induced vasodilation
-
McKay MK, Hester RL. Role of nitric oxide, adenosine, and ATP-sensitive potassium channels in insulin-induced vasodilation. Hypertension. 1996;28: 202-208.
-
(1996)
Hypertension
, vol.28
, pp. 202-208
-
-
McKay, M.K.1
Hester, R.L.2
-
15
-
-
0032853414
-
The role of adenosine in insulin-induced vasodilation
-
Abbink-Zandbergen EJ, Vervoort G, Tack CJ, Lutterman JA, Schaper NC, Smits P. The role of adenosine in insulin-induced vasodilation. J Cardiovasc Pharmacol. 1999;34:374-380.
-
(1999)
J Cardiovasc Pharmacol
, vol.34
, pp. 374-380
-
-
Abbink-Zandbergen, E.J.1
Vervoort, G.2
Tack, C.J.3
Lutterman, J.A.4
Schaper, N.C.5
Smits, P.6
-
16
-
-
0029789432
-
Insulin-stimulated production of nitric oxide is inhibited by wortmannin - direct measurement in vascular endothelial cells
-
Zeng G, Quon MJ. Insulin-stimulated production of nitric oxide is inhibited by wortmannin - direct measurement in vascular endothelial cells. J Clin Invest. 1996;98:894-898.
-
(1996)
J Clin Invest
, vol.98
, pp. 894-898
-
-
Zeng, G.1
Quon, M.J.2
-
17
-
-
0028800873
-
Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension
-
Taddei S, Virdis A, Mattei P, Natali A, Ferrannini E, Salvetti A. Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension. Circulation. 1995;92: 2911-2918.
-
(1995)
Circulation
, vol.92
, pp. 2911-2918
-
-
Taddei, S.1
Virdis, A.2
Mattei, P.3
Natali, A.4
Ferrannini, E.5
Salvetti, A.6
-
18
-
-
0028030813
-
Insulinmediated skeletal muscle vasodilation is nitric oxide dependent
-
Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron. AD. Insulinmediated skeletal muscle vasodilation is nitric oxide dependent. J Clin Invest. 1994;94:1172-1179.
-
(1994)
J Clin Invest
, vol.94
, pp. 1172-1179
-
-
Steinberg, H.O.1
Brechtel, G.2
Johnson, A.3
Fineberg, N.4
Baron, A.D.5
-
19
-
-
0028113927
-
Nitric oxide release accounts for insulin's vascular effects in humans
-
Scherrer U, Randin D, Vollenweider P, Vollenweider L, Nicod P. Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest. 1994;94:2511-2515.
-
(1994)
J Clin Invest
, vol.94
, pp. 2511-2515
-
-
Scherrer, U.1
Randin, D.2
Vollenweider, P.3
Vollenweider, L.4
Nicod, P.5
-
20
-
-
0031737307
-
Pharmacological modulation of endothelial function by insulin in the rat aorta
-
Laight DW, Kaw AV, Carrier MJ, Anggard EE. Pharmacological modulation of endothelial function by insulin in the rat aorta. J Pharm Pharmacol. 1998;50:1117-1120.
-
(1998)
J Pharm Pharmacol
, vol.50
, pp. 1117-1120
-
-
Laight, D.W.1
Kaw, A.V.2
Carrier, M.J.3
Anggard, E.E.4
-
21
-
-
0030708755
-
Insulin enhances endothelial α2-adrenergic vasorelaxation, by a pertussis toxin mechanism
-
Lembo G, Iaccarino G, Vecchione C, Barbato E, Morisco C, Monti F, Pattella L, Trimarco B. Insulin enhances endothelial α2-adrenergic vasorelaxation, by a pertussis toxin mechanism. Hypertension. 1997;30: 1128-1134.
-
(1997)
Hypertension
, vol.30
, pp. 1128-1134
-
-
Lembo, G.1
Iaccarino, G.2
Vecchione, C.3
Barbato, E.4
Morisco, C.5
Monti, F.6
Pattella, L.7
Trimarco, B.8
-
22
-
-
1342321663
-
Insulin, induces the release of vasodilator compounds from platelets by a nitric oxide-G kinase-VAMP-3-dependent pathway
-
Randriamboavonjy V, Schrader J, Busse R, Fleming I. Insulin, induces the release of vasodilator compounds from platelets by a nitric oxide-G kinase-VAMP-3-dependent pathway. J Exp Med. 2004;199:347-356.
-
(2004)
J Exp Med
, vol.199
, pp. 347-356
-
-
Randriamboavonjy, V.1
Schrader, J.2
Busse, R.3
Fleming, I.4
-
24
-
-
0032781886
-
Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3 ' : 5 ' -cyclic monophosphate and adenosine 3 ' : 5 ' -cyclic monophosphate concentrations
-
Trovati M, Massucco P, Mattiello L, Costamagna C, Aldieri E, Cavalot F, Anfossi G, Bosia A, Ghigo D. Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3 ' : 5 ' -cyclic monophosphate and adenosine 3 ' : 5 ' -cyclic monophosphate concentrations. Diabetologia. 1999;42:831-839.
-
(1999)
Diabetologia
, vol.42
, pp. 831-839
-
-
Trovati, M.1
Massucco, P.2
Mattiello, L.3
Costamagna, C.4
Aldieri, E.5
Cavalot, F.6
Anfossi, G.7
Bosia, A.8
Ghigo, D.9
-
25
-
-
0034603858
-
Roles for insulin receptor, PI3-kinase, and Akt in insulinsignaling pathways related to production of nitric oxide in human vascular endothelial cells
-
Zeng G, Nystrom FH, Ravichandran. LV, Cong LN, Kirby M, Mostowski H, Quon MJ. Roles for insulin receptor, PI3-kinase, and Akt in insulinsignaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation. 2000;101:1539-1545.
-
(2000)
Circulation
, vol.101
, pp. 1539-1545
-
-
Zeng, G.1
Nystrom, F.H.2
Ravichandran, L.V.3
Cong, L.N.4
Kirby, M.5
Mostowski, H.6
Quon, M.J.7
-
27
-
-
0037162342
-
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation. modification of signaling proteins in human coronary endothelial cells
-
Federici M, Menghini R, Mauriello A, Hribal ML, Ferrelli F, Lauro D, Sbraccia P, Spagnoli LG, Sesti G, Lauro R. Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation. modification of signaling proteins in human coronary endothelial cells. Circulation. 2002;106:466-472.
-
(2002)
Circulation
, vol.106
, pp. 466-472
-
-
Federici, M.1
Menghini, R.2
Mauriello, A.3
Hribal, M.L.4
Ferrelli, F.5
Lauro, D.6
Sbraccia, P.7
Spagnoli, L.G.8
Sesti, G.9
Lauro, R.10
-
28
-
-
33749329784
-
Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase
-
Wang XL, Zhang L, Youker K, Zhang MX, Wang J, LeMaire SA, Coselli JS, Shen YH. Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase. Diabetes. 2006;55:2301-2310.
-
(2006)
Diabetes
, vol.55
, pp. 2301-2310
-
-
Wang, X.L.1
Zhang, L.2
Youker, K.3
Zhang, M.X.4
Wang, J.5
LeMaire, S.A.6
Coselli, J.S.7
Shen, Y.H.8
-
29
-
-
0041663621
-
Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: A dual role for Akt and AP-1
-
Fisslthaler B, Benzing T, Busse R, Fleming I. Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: a dual role for Akt and AP-1. Nitric Oxide. 2003;8:253-261.
-
(2003)
Nitric Oxide
, vol.8
, pp. 253-261
-
-
Fisslthaler, B.1
Benzing, T.2
Busse, R.3
Fleming, I.4
-
30
-
-
48249126446
-
Inhibition of endothelial nitric oxide synthase activity by proline-rich tyrosine kinase 2 in response to fluid shear stress and insulin
-
In press
-
Fisslthaler B, Loot AE, Mohamed A, Busse R, Fleming I. Inhibition of endothelial nitric oxide synthase activity by proline-rich tyrosine kinase 2 in response to fluid shear stress and insulin. Circ Res. In press.
-
Circ Res
-
-
Fisslthaler, B.1
Loot, A.E.2
Mohamed, A.3
Busse, R.4
Fleming, I.5
|