Insight into why pyrrolidinyl peptide nucleic acid binding to DNA is more stable than the DNA·DNA duplex

Biochemical and Biophysical Research Communications

Volumn 372, Issue 4, 2008, Pages 765-771

  Siriwong, Khatcharin ^a   Chuichay, Parawan ^b   Saen oon, Suwipa ^c,d   Suparpprom, Chaturong ^d   Vilaivan, Tirayut ^d   Hannongbua, Supot ^d  

^a Khon Kaen University   (Thailand)

^b KASETSART UNIVERSITY   (Thailand)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Binding free energy; Molecular dynamics simulation; Peptide nucleic acids; PNA DNA; Pyrrolidinyl PNA

Indexed keywords

DNA; DOUBLE STRANDED DNA; PEPTIDE NUCLEIC ACID; PYRROLIDINYL PEPTIDE NUCLEIC ACID; SUGAR PHOSPHATE;

ARTICLE; COMPARATIVE STUDY; CONFORMATION; DNA BINDING; DNA STRAND; GAS; MELTING POINT; MOLECULAR DYNAMICS; MOLECULAR STABILITY; PRIORITY JOURNAL; SIMULATION; STATISTICAL SIGNIFICANCE; TEMPERATURE;

DNA; NUCLEIC ACID CONFORMATION; PEPTIDE NUCLEIC ACIDS; PYRROLIDINES; WATER;

EID: 46149107843     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.05.102     Document Type: Article

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