Effect of PNA backbone modifications on cyanine dye binding to PNA-DNA duplexes investigated by optical spectroscopy and molecular dynamics simulations

Journal of the American Chemical Society

Volumn 127, Issue 10, 2005, Pages 3339-3345

  Dilek, Isil ^a   Madrid, Marcela ^a   Singh, Rojendra ^a   Urrea, Christian P ^a   Armitage, Bruce A ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; AMINO ACIDS; BIOMATERIALS; DNA; DYES; NUCLEIC ACIDS; PERTURBATION TECHNIQUES; POLYPEPTIDES; ULTRAVIOLET SPECTROSCOPY;

HYBRIDIZATION; OPTICAL SPECTROSCOPY; PEPTIDE NUCLEIC ACID (PNA); STRUCTURAL PERTURBATIONS;

MOLECULAR DYNAMICS;

COMPLEMENTARY DNA; CYANINE DYE; DNA; PEPTIDE NUCLEIC ACID;

ARTICLE; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CONTROLLED STUDY; HYBRIDIZATION; MELTING POINT; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; TEMPERATURE DEPENDENCE; ULTRAVIOLET SPECTROSCOPY;

BENZOTHIAZOLES; CARBOCYANINES; CIRCULAR DICHROISM; COLORING AGENTS; COMPUTER SIMULATION; DNA; MODELS, MOLECULAR; NUCLEIC ACID HETERODUPLEXES; PEPTIDE NUCLEIC ACIDS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; THERMODYNAMICS;

EID: 14944340194     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja045145a     Document Type: Article

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