Pathological potential of astroglia

Physiological Research

Volumn 57, Issue SUPPL. 3, 2008, Pages

  Chvátal, Alexandr ^a,b   Anděrová, Miroslava ^a,b   Neprašová, Helena ^a,b   Prajerová, Iva ^a,b   Benešová, Jana ^a,b   Butenko, Olena ^a   Verkhratsky, Alexei ^a,c  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Acute brain trauma; Astrocyte; Astrogliosis; Brain damage and repair; Brain pathology; Ischaemia; Neurodegeneration

Indexed keywords

EID: 45949109220     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (87)

1. ABRAMOV, AY, CANEVARI, L, DUCHEN, MR: Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J Neurosci 24: 565-575, 2004a
2. ABRAMOV, AY, CANEVARI, L, DUCHEN, MR: Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture. Biochim Biophys Acta 1742: 81-87, 2004b
3. ALLEN, NJ, BARRES, BA: Signaling between glia and neurons: focus on synaptic plasticity. Curr Opin Neurobiol 15: 542-548, 2005
4. ALLEN, NJ, KARADOTTIR, R, ATTWELL, D: Reversal or reduction of glutamate and GABA transport in CNS pathology and therapy. Pflugers Arch 449: 132-142, 2004
5. ALZHEIMER, A: Über eine eigenartige Erkrankung der Hirnrinde. Allg. Z. Psychiat. Psych.-Gericht. Med. 64: 146-148, 1907
6. ANDEROVA, M, ANTONOVA, T, PETRIK, D, NEPRASOVA, H, CHVATAL, A, SYKOVA, E: Voltage-dependent potassium currents in hypertrophied rat astrocytes after a cortical stab wound. Glia 48: 311-326, 2004
7. +, hypotonic stress, and cortical spreading depression on astrocyte swelling in GFAP-deficient mice. Glia 35: 189-203, 2001
8. ARAQUE, A, PARPURA, V, SANZGIRI, RP, HAYDON, PG: Tripartite synapses: glia, the unacknowledged partner. Trends Neurosci 22: 208-215, 1999
9. BARBEITO, LH, PEHAR, M, CASSINA, P, VARGAS, MR, PELUFFO, H, VIERA, L, ESTEVEZ, AG, BECKMAN, JS: A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. Brain Res Brain Res Rev 47: 263-274, 2004
10. BARRES, BA: A new role for glia: generation of neurons! Cell 97: 667-670, 1999
11. BERNINGER, B, HACK, MA, GOTZ, M: Neural stem cells: on where they hide, in which disguise, and how we may lure them out. Handb Exp Pharmacol: 319-360, 2006
12. BEZZI, P, GUNDERSEN, V, GALBETE, JL, SEIFERT, G, STEINHAUSER, C, PILATI, E, VOLTERRA, A: Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate. Nat Neurosci 7: 613-620, 2004
13. BIGNAMI, A, DAHL, D: Specificity of the glial fibrillary acidic protein for astroglia. J Histochem Cytochem 25: 466-469., 1977
14. BORDEY, A, LYONS, SA, HABLITZ, JJ, SONTHEIMER, H: Electrophysiological characteristics of reactive astrocytes in experimental cortical dysplasia. J Neurophysiol 85: 1719-1731., 2001
15. BRUZZONE, R, GIAUME, C: Connexins and information transfer through glia. Adv Exp Med Biol 468: 321-337, 1999
16. BUDD, SL, LIPTON, SA: Calcium tsunamis: do astrocytes transmit cell death messages via gap junctions during ischemia? Nat Neurosci 1: 431-432, 1998
17. BURNARD, DM, CRICHTON, SA, MACVICAR, BA: Electrophysiological properties of reactive glial cells in the kainate- lesioned hippocampal slice. Brain Res 510: 43-52., 1990
18. CHVATAL, A, ANDEROVA, M, ZIAK, D, SYKOVA, E: Glial depolarization evokes a larger potassium accumulation around oligodendrocytes than around astrocytes in gray matter of rat spinal cord slices. J Neurosci Res 56: 493-505, 1999
19. CONTRERAS, JE, SANCHEZ, HA, VELIZ, LP, BUKAUSKAS, FF, BENNETT, MV, SAEZ, JC: Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue. Brain Res Brain Res Rev 47: 290-303, 2004
20. COTRINA, ML, KANG, J, LIN, JH, BUENO, E, HANSEN, TW, HE, L, LIU, Y, NEDERGAARD, M: Astrocytic gap junctions remain open during ischemic conditions. J Neurosci 18: 2520-2537, 1998
21. + homeostasis and altered electrophysiological properties of post-traumatic hippocampal glia. J Neurosci 19: 8152-8162., 1999
22. DANBOLT, NC: Glutamate uptake. Progr. Neurobiol. 65: 1-105, 2001
23. DEL BIGIO, MR, OMARA, F, FEDOROFF, S: Astrocyte proliferation in culture following exposure to potassium ion. Neuroreport 5: 639-641, 1994
24. DERMIETZEL, R: Gap junction wiring: a 'new' principle in cell-to-cell communication in the nervous system? Brain Res Brain Res Rev 26: 176-183, 1998
25. DICKSON, DW: The pathogenesis of senile plaques. J Neuropathol Exp Neurol 56: 321-339, 1997
26. ENCLANCHER, F, PERRAUD, F, FALTIN, J, LABOURDETTE, G, SENSENBRENNER, M: Reactive astrogliosis after basic fibroblast growth factor (bFGF) injection in injured neonatal rat brain. Glia 3: 502-509, 1990
27. GIAUME, C, FROMAGET, C, EL AOUMARI, A, CORDIER, J, GLOWINSKI, J, GROS, D: Gap junctions in cultured astrocytes: single-channel currents and characterization of channel-forming protein. Neuron 6: 133-143, 1991
28. GIAUME, C, KIRCHHOFF, F, MATUTE, C, REICHENBACH, A, VERKHRATSKY, A: Glia: the fulcrum of brain diseases. Cell Death Differ 14: 1324-1335, 2007
29. HAYDON, PG, CARMIGNOTO, G: Astrocyte control of synaptic transmission and neurovascular coupling. Physiol Rev 86: 1009-1031, 2006
30. HOZUMI, I, AQUINO, DA, NORTON, WT: GFAP mRNA levels following stab wounds in rat brain. Brain Res 534: 291-294., 1990
31. JABS, R, PATERSON, IA, WALZ, W: Qualitative analysis of membrane currents in glial cells from normal and gliotic tissue in situ: down-regulation of Na+ current and lack of P2 purinergic responses. Neuroscience 81: 847-860., 1997
32. KÁLMÁN, M, AJTAI, BM: Lesions do not provoke GFAP-expression in the GFAP-immunonegative areas of the teleost brain. Ann Anat 182: 459-463, 2000
33. KIMELBERG, HK, RUTLEDGE, E, GODERIE, S, CHARNIGA, C: Astrocytic swelling due to hypotonic or high K+ medium causes inhibition of glutamate and aspartate uptake and increases their release. J Cereb Blood Flow Metab 15: 409-416, 1995
34. KIRISCHUK, S, KETTENMANN, H, VERKHRATSKY, A: Membrane currents and cytoplasmic sodium transients generated by glutamate transport in Bergmann glial cells. Pflugers Arch 454: 245-252, 2007
35. KOFUJI, P, NEWMAN, EA: Potassium buffering in the central nervous system. Neuroscience 129: 1045-1056, 2004
36. LALO, U, PANKRATOV, Y, KIRCHHOFF, F, NORTH, RA, VERKHRATSKY, A: NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J Neurosci 26: 2673-2683, 2006
37. LIN, JH, WEIGEL, H, COTRINA, ML, LIU, S, BUENO, E, HANSEN, AJ, HANSEN, TW, GOLDMAN, S, NEDERGAARD, M: Gap-junction-mediated propagation and amplification of cell injury. Nat Neurosci 1: 494-500, 1998
38. MACFARLANE, SN, SONTHEIMER, H: Electrophysiological changes that accompany reactive gliosis in vitro. J Neurosci 17: 7316-7329., 1997
39. MACFARLANE, SN, SONTHEIMER, H: Spinal cord astrocytes display a switch from TTX-sensitive to TTX- resistant sodium currents after injury-induced gliosis in vitro. J Neurophysiol 79: 2222-2226., 1998
40. MAGISTRETTI, PJ: Neuron-glia metabolic coupling and plasticity. J Exp Biol 209: 2304-2311, 2006
41. MITCHELL, JD, BORASIO, GD: Amyotrophic lateral sclerosis. Lancet 369: 2031-2041, 2007
42. NAGELE, RG, D'ANDREA, MR, LEE, H, VENKATARAMAN, V, WANG, HY: Astrocytes accumulate A beta 42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains. Brain Res 971: 197-209, 2003
43. NAGELE, RG, WEGIEL, J, VENKATARAMAN, V, IMAKI, H, WANG, KC: Contribution of glial cells to the development of amyloid plaques in Alzheimer's disease. Neurobiol Aging 25: 663-674, 2004
44. NEDERGAARD, M, DIRNAGL, U: Role of glial cells in cerebral ischemia. Glia 50: 281-286, 2005
45. NEDERGAARD, M, RANSOM, B, GOLDMAN, SA: New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci 26: 523-530, 2003
46. + evokes changes in voltage-dependent K(+) and Na (+) currents and volume regulation in astrocytes. Pflugers Arch 453: 839-849, 2007
47. NICOTERA, P, PETERSEN, OH, MELINO, G, VERKHRATSKY, A: Janus a god with two faces: death and survival utilise same mechanisms conserved by evolution. Cell Death Differ 14: 1235-1236, 2007
48. NOLTE, C, MATYASH, M, PIVNEVA, T, SCHIPKE, CG, OHLEMEYER, C, HANISCH, UK, KIRCHHOFF, F, KETTENMANN, H: GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue. Glia 33: 72-86, 2001
49. OBERHEIM, NA, WANG, X, GOLDMAN, S, NEDERGAARD, M: Astrocytic complexity distinguishes the human brain. Trends Neurosci 29: 547-553, 2006
50. ORKAND, RK, NICHOLLS, JG, KUFFLER, SW: Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. J Neurophysiol 29: 788-806, 1966
51. PASANTES MORALES, H, SCHOUSBOE, A: Volume regulation in astrocytes: a role for taurine as an osmoeffector. J Neurosci Res 20: 503-509, 1988
52. PEKNY, M, NILSSON, M: Astrocyte activation and reactive gliosis. Glia 50: 427-434, 2005
53. + channel Kir2.3 (IRK3) in reactive astrocytes from adult rat brain. Glia 31: 181-192., 2000
54. + inward rectifier currents in reactive astrocytes from adult rat brain. Glia 27: 213-225, 1999
55. ROITBAK, T, SYKOVA, E: Diffusion barriers evoked in the rat cortex by reactive astrogliosis. Glia 28: 40-48., 1999
56. ROSSI, DJ, BRADY, JD, MOHR, C: Astrocyte metabolism and signaling during brain ischemia. Nat Neurosci 10: 1377-1386, 2007
57. SCEMES, E, GIAUME, C: Astrocyte calcium waves: what they are and what they do. Glia 54: 716-725, 2006
58. SCHRODER, W, HAGER, G, KOUPRIJANOVA, E, WEBER, M, SCHMITT, AB, SEIFERT, G, STEINHAUSER, C: Lesion-induced changes of electrophysiological properties in astrocytes of the rat dentate gyrus. Glia 28: 166-174., 1999
59. SELKOE, DJ: Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81: 741-766, 2001
60. SOMJEN, GG: Extracellular potassium in the mammalian central nervous system. Annu Rev Physiol 41: 159-177, 1979
61. SOMJEN, GG: Mechanisms of spreading depression and hypoxic spreading depression-like depolarization. Physiol Rev 81: 1065-1096, 2001
62. + accumulation in the central nervous system. Prog Biophys Mol Biol 42: 135-189, 1983
63. SYKOVA, E: Extracellular space volume and geometry of the rat brain after ischemia and central injury. Adv Neurol 73: 121-135, 1997
64. SYKOVA, E: Glia and volume transmission during physiological and pathological states. J Neural Transm 112: 137-147, 2005
65. SYKOVA, E, CHVATAL, A: Glial cells and volume transmission in the CNS. Neurochem Int 36: 397-409., 2000
66. SYKOVA, E, SVOBODA, J, SIMONOVA, Z, JENDELOVA, P: Role of astrocytes in ionic and volume homeostasis in spinal cord during development and injury. Prog Brain Res 94: 47-56, 1992
67. SYKOVA, E, VARGOVA, L, PROKOPOVA, S, SIMONOVA, Z: Glial swelling and astrogliosis produce diffusion barriers in the rat spinal cord. Glia 25: 56-70, 1999
68. TOWER, DB: A century of neuronal and neuroglial interactions, and their pathological implications: an overview. Prog Brain Res 94: 3-17, 1992
69. ULLIAN, EM, CHRISTOPHERSON, KS, BARRES, BA: Role for glia in synaptogenesis. Glia 47: 209-216, 2004
70. VARGOVA, L, CHVATAL, A, ANDEROVA, M, KUBINOVA, S, ZIAK, D, SYKOVA, E: Effect of osmotic stress on potassium accumulation around glial cells and extracellular space volume in rat spinal cord slices. J Neurosci Res 65: 129-138, 2001
71. VERKHRATSKY, A: Calcium ions and integration in neural circuits. Acta Physiol (Oxf) 187: 357-369, 2006a
72. VERKHRATSKY, A: Patching the glia reveals the functional organisation of the brain. Pflugers Arch 453: 411-420, 2006b
73. VERKHRATSKY, A, BUTT, A: Glial Neurobiology. A textbook. John Wiley & Sons, Chichester.2007
74. VERKHRATSKY, A, KIRCHHOFF, F: Glutamate-mediated neuronal-glial transmission. J Anat 210: 651-660, 2007a
75. VERKHRATSKY, A, KIRCHHOFF, F: NMDA Receptors in Glia. Neuroscientist 13: 28-37, 2007b
76. VERKHRATSKY, A, ORKAND, RK, KETTENMANN, H: Glial calcium: homeostasis and signaling function. Physiol Rev 78: 99-141, 1998
77. VERKHRATSKY, A, STEINHAUSER, C: Ion channels in glial cells. Brain Res Brain Res Rev 32: 380-412, 2000
78. VERKHRATSKY, A, TOESCU, EC: Neuronal-glial networks as substrate for CNS integration. J Cell Mol Med 10: 826-836, 2006
79. VIJAYAN, VK, LEE, YL, ENG, LF: Increase in glial fibrillary acidic protein following neural trauma. Mol Chem Neuropathol 13: 107-118., 1990
80. VOLTERRA, A, MELDOLESI, J: Astrocytes, from brain glue to communication elements: the revolution continues. Nat Rev Neurosci 6: 626-640, 2005
81. +, and pH in the developing rat cortex and corpus callosum. J Cereb Blood Flow Metab 17: 191-203, 1997
82. WALZ, W: Role of astrocytes in the spreading depression signal between ischemic core and penumbra. Neurosci Biobehav Rev 21: 135-142, 1997
83. WESTBROOK, GL: Glutamate receptors and excitotoxicity. Res Publ Assoc Res Nerv Ment Dis 71: 35-50, 1993
84. WISNIEWSKI, HM, WEGIEL, J: Spatial relationships between astrocytes and classical plaque components. Neurobiol Aging 12: 593-600, 1991
85. YAGITA, Y, KITAGAWA, K, SASAKI, T, MIYATA, T, OKANO, H, HORI, M, MATSUMOTO, M: Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia. J Neurosci Res 69: 750-756, 2002
86. +-ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death. Biochem Pharmacol 66: 1601-1609, 2003
87. ZONTA, M, ANGULO, MC, GOBBO, S, ROSENGARTEN, B, HOSSMANN, KA, POZZAN, T, CARMIGNOTO, G: Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat Neurosci 6: 43-50, 2003