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Volumn 18, Issue 5, 2008, Pages 385-398

Metabolomics in lung inflammation: A high-resolution 1H NMR study of mice exposedto silica dust

Author keywords

1H NMR; Inflammation; MAS; Metabolite; Metabolomics; Molecular Pathways; MRI

Indexed keywords

CHOLINE; CREATINE; GLUCOSE; GLUTAMIC ACID; GLYCEROPHOSPHORYLCHOLINE; GLYCINE; GLYCOGEN; HYDROXYPROLINE; LACTIC ACID; LYSINE; PHOSPHORYLCHOLINE; PROLINE; SILICON DIOXIDE;

EID: 45849133740     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510701611032     Document Type: Article
Times cited : (53)

References (89)
  • 1
    • 0032893756 scopus 로고    scopus 로고
    • Malignant transformation alters membrane choline phospholipids metabolism of human mammary epithelial cells
    • Aboagye, E.O., and Bhujwalla, Z.M. 1999. Malignant transformation alters membrane choline phospholipids metabolism of human mammary epithelial cells. Cancer Res. 59:80-84.
    • (1999) Cancer Res , vol.59 , pp. 80-84
    • Aboagye, E.O.1    Bhujwalla, Z.M.2
  • 2
    • 0027567431 scopus 로고
    • 19F NMR spectra of suspended leukemic cells
    • 19F NMR spectra of suspended leukemic cells. NMR Biomed. 6:125-129.
    • (1993) NMR Biomed , vol.6 , pp. 125-129
    • Adebodun, F.1    Post, J.2
  • 3
    • 0000504594 scopus 로고
    • An efficient decoupler coil design which reduces heating in conductive samples in superconducting spectrometers
    • Alderman, D.W., and Grant, D.M. 1979. An efficient decoupler coil design which reduces heating in conductive samples in superconducting spectrometers. J. Magn. Reson. 36:47-451.
    • (1979) J. Magn. Reson , vol.36 , pp. 47-451
    • Alderman, D.W.1    Grant, D.M.2
  • 4
    • 4043165350 scopus 로고
    • Removal of dipolar broadening of NMR spectra of solids by specimen rotation
    • Andrew, E.R., and Eades, R.G. 1959. Removal of dipolar broadening of NMR spectra of solids by specimen rotation. Nature 183:1802.
    • (1959) Nature , vol.183 , pp. 1802
    • Andrew, E.R.1    Eades, R.G.2
  • 5
    • 33845326963 scopus 로고
    • Two-dimensional sideband separation in magic-angle-spinning NMR
    • Antzutkin, O.N., Shekar, S.C., and Levitt, M.H. 1995. Two-dimensional sideband separation in magic-angle-spinning NMR. J. Magn. Reson. A115:7-19.
    • (1995) J. Magn. Reson , vol.A115 , pp. 7-19
    • Antzutkin, O.N.1    Shekar, S.C.2    Levitt, M.H.3
  • 8
    • 19144371287 scopus 로고    scopus 로고
    • NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition
    • Bollard, M.E., Stanley, E.G., Lindon, J.C., Nicholson, J.K., and Holmes, E. 2005. NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition. NMR Biomed. 18:143-162.
    • (2005) NMR Biomed , vol.18 , pp. 143-162
    • Bollard, M.E.1    Stanley, E.G.2    Lindon, J.C.3    Nicholson, J.K.4    Holmes, E.5
  • 10
    • 0034838110 scopus 로고    scopus 로고
    • The role of inflammation, oxidative stress, and proliferation in silica-induced lung disease: A species comparison
    • Carter, J.D., and Driscoll, K.E. 2001. The role of inflammation, oxidative stress, and proliferation in silica-induced lung disease: a species comparison. J. Env. Pathol. Toxicol. Oncol. 20:33-43.
    • (2001) J. Env. Pathol. Toxicol. Oncol , vol.20 , pp. 33-43
    • Carter, J.D.1    Driscoll, K.E.2
  • 11
    • 0035913738 scopus 로고    scopus 로고
    • Biochemical analysis using high-resolution magic angle spinning NMR spectroscopy distinguishes lipoma-like well-differentiated liposarcoma from normal fat
    • Chen, J., Enloe, B.M., Fletcher, C.D., Cory, D.G., and Singer, S. 2001. Biochemical analysis using high-resolution magic angle spinning NMR spectroscopy distinguishes lipoma-like well-differentiated liposarcoma from normal fat. J. Am. Chem. Soc. 123:9200-9201.
    • (2001) J. Am. Chem. Soc , vol.123 , pp. 9200-9201
    • Chen, J.1    Enloe, B.M.2    Fletcher, C.D.3    Cory, D.G.4    Singer, S.5
  • 12
    • 0030947540 scopus 로고    scopus 로고
    • Quantitative neuropathology by high resolution magic angle spinning proton magnetic resonance spectroscopy
    • Cheng, L.L., Ma, M.J., Becerra, L., Ptak, T., Tracey, I., Lackner, A., and Gonzalez, R.G. 1997. Quantitative neuropathology by high resolution magic angle spinning proton magnetic resonance spectroscopy. Proc. Natl. Acad. Sci. USA 94:6408-6413.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6408-6413
    • Cheng, L.L.1    Ma, M.J.2    Becerra, L.3    Ptak, T.4    Tracey, I.5    Lackner, A.6    Gonzalez, R.G.7
  • 13
    • 0037348405 scopus 로고    scopus 로고
    • An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy
    • Coen, M., Lenz, E.M., Nicholson, J.K., Wilson, I.D., Pognan, F., and Lindon, J.C. 2003. An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy. Chem. Res. Toxicol. 16:295-303.
    • (2003) Chem. Res. Toxicol , vol.16 , pp. 295-303
    • Coen, M.1    Lenz, E.M.2    Nicholson, J.K.3    Wilson, I.D.4    Pognan, F.5    Lindon, J.C.6
  • 15
    • 0036303519 scopus 로고    scopus 로고
    • Silica-induced generation of extracellular factor(s) increases reactive oxygen species in human bronchial epithelial cells
    • Deshpande, A., Narayanan, P.K., and Lehnert, B.E. 2002. Silica-induced generation of extracellular factor(s) increases reactive oxygen species in human bronchial epithelial cells. Toxicol. Sci. 67:275-283.
    • (2002) Toxicol. Sci , vol.67 , pp. 275-283
    • Deshpande, A.1    Narayanan, P.K.2    Lehnert, B.E.3
  • 16
    • 0022475802 scopus 로고
    • Induction of intra- and extra-cellular phospholipids in the lungs of rats exposed to silica
    • Dethloff, L.A., Gilmore, L.B., Brody, A.R., and Hook, G.E. 1986a. Induction of intra- and extra-cellular phospholipids in the lungs of rats exposed to silica. Biochem. J. 233:111-118.
    • (1986) Biochem. J , vol.233 , pp. 111-118
    • Dethloff, L.A.1    Gilmore, L.B.2    Brody, A.R.3    Hook, G.E.4
  • 19
    • 0034107229 scopus 로고    scopus 로고
    • Intratracheal instillation as an exposure technique for evaluation of respiratory tract toxicity: Uses and limitations
    • Driscoll, K.E., Costa, D.L., Hatch, G., Henderson, R., Oberdorster, G., Salem, H., and Schlesinger, R.B. 2000. Intratracheal instillation as an exposure technique for evaluation of respiratory tract toxicity: uses and limitations. Toxicol. Sci. 55:24-35.
    • (2000) Toxicol. Sci , vol.55 , pp. 24-35
    • Driscoll, K.E.1    Costa, D.L.2    Hatch, G.3    Henderson, R.4    Oberdorster, G.5    Salem, H.6    Schlesinger, R.B.7
  • 21
    • 16244402990 scopus 로고    scopus 로고
    • Metabolomics: Current analytical platforms and methodologies
    • Dunn, W.B., and Ellis, D.I. 2005. Metabolomics: current analytical platforms and methodologies. Trends Anal. Chem. 24:285-294.
    • (2005) Trends Anal. Chem , vol.24 , pp. 285-294
    • Dunn, W.B.1    Ellis, D.I.2
  • 22
    • 0034959944 scopus 로고    scopus 로고
    • Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks
    • Fiehn, O. 2001. Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks. Compar. Func. Genomics 2:155-168.
    • (2001) Compar. Func. Genomics , vol.2 , pp. 155-168
    • Fiehn, O.1
  • 25
    • 49049139340 scopus 로고
    • Magic-angle sample spinning of liquids
    • Garroway, A.N. 1982. Magic-angle sample spinning of liquids. J. Magn. Reson. 49:168-171.
    • (1982) J. Magn. Reson , vol.49 , pp. 168-171
    • Garroway, A.N.1
  • 26
    • 29644438451 scopus 로고    scopus 로고
    • Acute effects of iron-particle radiation on immunity. Part II: Leukocyte activation, cytokines and adhesion
    • Gridley, D.S., Dutta-Roy, R., Andres, M.L., Nelson, G.A., and Pecauta, M.J. 2006. Acute effects of iron-particle radiation on immunity. Part II: leukocyte activation, cytokines and adhesion. Radiat. Res. 165:78-87.
    • (2006) Radiat. Res , vol.165 , pp. 78-87
    • Gridley, D.S.1    Dutta-Roy, R.2    Andres, M.L.3    Nelson, G.A.4    Pecauta, M.J.5
  • 27
    • 2942709840 scopus 로고    scopus 로고
    • Metabolic profiles to define the genome: Can we hear the phenotypes?
    • Griffin, J.L. 2004. Metabolic profiles to define the genome: can we hear the phenotypes? Phil. Trans. R. Soc. Lond. B 359:857-871.
    • (2004) Phil. Trans. R. Soc. Lond. B , vol.359 , pp. 857-871
    • Griffin, J.L.1
  • 28
    • 0033002315 scopus 로고    scopus 로고
    • Leukocyte glycolysis and lactate output in animal sepsis and ex vivo human blood
    • Haji-Michael, P.G., Ladriere, L., Sener, A., Vincent, J.L., and Malaisse, W.J. 1999. Leukocyte glycolysis and lactate output in animal sepsis and ex vivo human blood. Metabolism 48:779-785.
    • (1999) Metabolism , vol.48 , pp. 779-785
    • Haji-Michael, P.G.1    Ladriere, L.2    Sener, A.3    Vincent, J.L.4    Malaisse, W.J.5
  • 30
    • 0036011150 scopus 로고    scopus 로고
    • 1H NMR spectroscopy in rat liver using magic angle turning at a 1 Hz spinning rate
    • 1H NMR spectroscopy in rat liver using magic angle turning at a 1 Hz spinning rate. Magn. Reson. Med. 47:829-836.
    • (2002) Magn. Reson. Med , vol.47 , pp. 829-836
    • Hu, J.Z.1    Rommerein, D.N.2    Wind, R.A.3
  • 32
    • 0036920243 scopus 로고    scopus 로고
    • The evaluation of different slow-MAS techniques at low spinning rates in aqueous samples and in the presence of magnetic susceptibility gradient
    • Hu, J.Z., and Wind, R.A. 2002. The evaluation of different slow-MAS techniques at low spinning rates in aqueous samples and in the presence of magnetic susceptibility gradient. J. Magn. Reson. 159:92-100.
    • (2002) J. Magn. Reson , vol.159 , pp. 92-100
    • Hu, J.Z.1    Wind, R.A.2
  • 33
    • 0042995352 scopus 로고    scopus 로고
    • Sensitivity-enhanced phase corrected ultra-slow magic angle turning using multiple-echo data acquisition
    • Hu, J.Z., and Wind, R.A. 2003. Sensitivity-enhanced phase corrected ultra-slow magic angle turning using multiple-echo data acquisition. J. Magn. Reson. 163:149-162.
    • (2003) J. Magn. Reson , vol.163 , pp. 149-162
    • Hu, J.Z.1    Wind, R.A.2
  • 34
    • 58149364144 scopus 로고
    • Magic-angle-turning experiments for measuring chemical-shift-tensor principal values in powdered solids
    • Hu, J.Z., Wang, W., Liu, F., Solum, M.S., Alderman, D.W., Pugmire, R.J., and Grant, D.M. 1995. Magic-angle-turning experiments for measuring chemical-shift-tensor principal values in powdered solids. J. Magn. Reson. A 113:210-222.
    • (1995) J. Magn. Reson. A , vol.113 , pp. 210-222
    • Hu, J.Z.1    Wang, W.2    Liu, F.3    Solum, M.S.4    Alderman, D.W.5    Pugmire, R.J.6    Grant, D.M.7
  • 36
    • 33644834457 scopus 로고    scopus 로고
    • 1H relaxation times of metabolites in biological samples obtained with non-destructive ex vivo slow-MAS NMR
    • 1H relaxation times of metabolites in biological samples obtained with non-destructive ex vivo slow-MAS NMR. Magn. Reson. Chem. 44:269-275.
    • (2006) Magn. Reson. Chem , vol.44 , pp. 269-275
    • Hu, J.Z.1    Wind, R.A.2    Rommereim, D.N.3
  • 37
    • 84889377495 scopus 로고    scopus 로고
    • Jue, T. 2005. Bioenergetics implication of metabolic fluctuation during muscle contraction. In Metabolomics by In Vivo NMR. ed. R.G. Shulman and D.L. Rothman DL, 104-123. John Wiley & Sonsw Ltd, England.
    • Jue, T. 2005. Bioenergetics implication of metabolic fluctuation during muscle contraction. In Metabolomics by In Vivo NMR. ed. R.G. Shulman and D.L. Rothman DL, 104-123. John Wiley & Sonsw Ltd, England.
  • 38
    • 14744284392 scopus 로고    scopus 로고
    • Characterization of intervertebral disk degeneration by high-resolution magic angle spinning (HR-MAS) spectroscopy
    • Keshari, K.R., Zektzer, A.S., Swanson, M.G., Majumdar, S., Lotz, J.C., and Kurhanewicz, J. 2005. Characterization of intervertebral disk degeneration by high-resolution magic angle spinning (HR-MAS) spectroscopy. Magn. Reson. Med. 53:519-527.
    • (2005) Magn. Reson. Med , vol.53 , pp. 519-527
    • Keshari, K.R.1    Zektzer, A.S.2    Swanson, M.G.3    Majumdar, S.4    Lotz, J.C.5    Kurhanewicz, J.6
  • 43
    • 0042338519 scopus 로고    scopus 로고
    • So what's the deal with metabonomics? Metabonomics measures the fingerprint of biochemical perturbations caused by disease, drugs, and toxins
    • Lindon, J.C., Holmes, E., and Nicholson, J.K. 2003. So what's the deal with metabonomics? Metabonomics measures the fingerprint of biochemical perturbations caused by disease, drugs, and toxins. Anal. Chem. 75:384A-391A.
    • (2003) Anal. Chem , vol.75
    • Lindon, J.C.1    Holmes, E.2    Nicholson, J.K.3
  • 45
    • 0034368580 scopus 로고    scopus 로고
    • Metabonomics: Metabolic processes studies by NMR spectroscopy of biofluids
    • Lindon, J.C., Nicholson, J.K., Holmes, E., and Everett, J.R. 2000. Metabonomics: metabolic processes studies by NMR spectroscopy of biofluids. Concepts Magn. Reson. 12:289-320.
    • (2000) Concepts Magn. Reson , vol.12 , pp. 289-320
    • Lindon, J.C.1    Nicholson, J.K.2    Holmes, E.3    Everett, J.R.4
  • 47
    • 0023692992 scopus 로고
    • Stimulation of surfactant phospholipid biosynthesis in the lungs of rats treated with silica
    • Miller, B.E., and Hook, G.E. 1988. Stimulation of surfactant phospholipid biosynthesis in the lungs of rats treated with silica. Biochem. J. 253:659-665.
    • (1988) Biochem. J , vol.253 , pp. 659-665
    • Miller, B.E.1    Hook, G.E.2
  • 48
    • 0030884710 scopus 로고    scopus 로고
    • Gradient, high-resolution, magic-angle spinning NMR spectroscopy of human adipocyte tissue
    • Millis, K.K., Maas, W.E., Cory, D.G., and Singer, S. 1997. Gradient, high-resolution, magic-angle spinning NMR spectroscopy of human adipocyte tissue. Magn. Reson. Med. 38:399-403.
    • (1997) Magn. Reson. Med , vol.38 , pp. 399-403
    • Millis, K.K.1    Maas, W.E.2    Cory, D.G.3    Singer, S.4
  • 49
    • 0023890390 scopus 로고
    • Organization of lipids in the plasma membranes of malignant and stimulated cells: A new model
    • Mountford, C.E., and Wright, L.C. 1988. Organization of lipids in the plasma membranes of malignant and stimulated cells: a new model. Trends Biochem. Sci. 13:172-177.
    • (1988) Trends Biochem. Sci , vol.13 , pp. 172-177
    • Mountford, C.E.1    Wright, L.C.2
  • 51
    • 0032694577 scopus 로고    scopus 로고
    • Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson, J.K., Lindon, J.C., and Holmes, E. 1999. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29(11):1181-1189.
    • (1999) Xenobiotica , vol.29 , Issue.11 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 53
    • 18844406983 scopus 로고    scopus 로고
    • Crystalline and amorphous silica differentially regulate the cyclo-oxygenase-prostaglandin pathway in pulmonary fibroblasts: Implications for pulmonary fibrosis
    • O'Reilly, K.M.A., Phipps, R.P., Thatcher, T.H., Graf, B.A., Van Kirk, J., and Sime, P.J. 2005. Crystalline and amorphous silica differentially regulate the cyclo-oxygenase-prostaglandin pathway in pulmonary fibroblasts: Implications for pulmonary fibrosis. Am. J. Physio Lung Cell Mol. Physiol. 288(6):L1010.
    • (2005) Am. J. Physio Lung Cell Mol. Physiol , vol.288 , Issue.6
    • O'Reilly, K.M.A.1    Phipps, R.P.2    Thatcher, T.H.3    Graf, B.A.4    Van Kirk, J.5    Sime, P.J.6
  • 56
    • 0036384102 scopus 로고    scopus 로고
    • NMR-based metabolomics
    • Reo, N.V. 2002. NMR-based metabolomics. Drug. Chem. Toxicol. 25:375-382.
    • (2002) Drug. Chem. Toxicol , vol.25 , pp. 375-382
    • Reo, N.V.1
  • 57
    • 0026922073 scopus 로고
    • Phospholipid metabolites as indicators of cancer cell function
    • Ruiz-Cabello, J., and Cohen, J.S. 1992. Phospholipid metabolites as indicators of cancer cell function. NMR Biomed. 5:226-233.
    • (1992) NMR Biomed , vol.5 , pp. 226-233
    • Ruiz-Cabello, J.1    Cohen, J.S.2
  • 58
    • 0034956390 scopus 로고    scopus 로고
    • 13C HR-MAS NMR investigations on native and enzymatically digested bovine nasal cartilage
    • 13C HR-MAS NMR investigations on native and enzymatically digested bovine nasal cartilage. MAGMA. 13:19-27.
    • (2001) MAGMA , vol.13 , pp. 19-27
    • Schiller, J.1    Naji, L.2    Huster, D.3    Kaufmann, J.4    Arnold, K.5
  • 59
    • 0036151429 scopus 로고    scopus 로고
    • Mechanisms of genotoxicity of particles and fibres
    • Schins, R.P.F. 2002. Mechanisms of genotoxicity of particles and fibres. Inhal. Toxicol. 14:57-78.
    • (2002) Inhal. Toxicol , vol.14 , pp. 57-78
    • Schins, R.P.F.1
  • 60
    • 21044443577 scopus 로고    scopus 로고
    • Automated 20 kpsi RPLC-MS and MS/MS with chromatographic peak capacities of 1000-1500 and capabilities in proteomics and metabolomics
    • Shen, Y., Zhang, R., Moore, F.J., Kim, J., Metz, T.O., Hixson, K.K., Zhao, R., Livesay, E.A., Udseth, H.R., and Smith, R.D. 2005. Automated 20 kpsi RPLC-MS and MS/MS with chromatographic peak capacities of 1000-1500 and capabilities in proteomics and metabolomics. Anal. Chem. 77:3090-3100.
    • (2005) Anal. Chem , vol.77 , pp. 3090-3100
    • Shen, Y.1    Zhang, R.2    Moore, F.J.3    Kim, J.4    Metz, T.O.5    Hixson, K.K.6    Zhao, R.7    Livesay, E.A.8    Udseth, H.R.9    Smith, R.D.10
  • 62
    • 0024345536 scopus 로고
    • The chemical properties of silica particle surface in relation to silica-cell interaction
    • Shi, X., Dalal, N.S., Hu, X.N., and Vallyathan, V. 1989. The chemical properties of silica particle surface in relation to silica-cell interaction. J. Toxicol. Environ. Health 27:435-454.
    • (1989) J. Toxicol. Environ. Health , vol.27 , pp. 435-454
    • Shi, X.1    Dalal, N.S.2    Hu, X.N.3    Vallyathan, V.4
  • 64
    • 0029558696 scopus 로고
    • Generation of reactive oxygen species by quartz particles and its implication for cellular damage
    • Shi, X., Mao, Y., Daniel, L.N., Saffiotti, U., Dalal, N.S., and Vallyathan, V. 1995. Generation of reactive oxygen species by quartz particles and its implication for cellular damage. Appl. Occup. Environ. Hyg. 10:1138-1144.
    • (1995) Appl. Occup. Environ. Hyg , vol.10 , pp. 1138-1144
    • Shi, X.1    Mao, Y.2    Daniel, L.N.3    Saffiotti, U.4    Dalal, N.S.5    Vallyathan, V.6
  • 65
    • 0033845110 scopus 로고    scopus 로고
    • Inhaled particulate matter causes expression of nuclear factor (NF)-kappaB-related gene and oxidant-dependent NF-kappaB activation in vitro
    • Shukla, A., Timblin, C., BeruBe, K., Gordon, T., McKinney, W., Driscoll, K., Vacek, P., and Mossman, B.T. 2000. Inhaled particulate matter causes expression of nuclear factor (NF)-kappaB-related gene and oxidant-dependent NF-kappaB activation in vitro. Am. J. Respir. Cell Mol. Biol. 23:182-187.
    • (2000) Am. J. Respir. Cell Mol. Biol , vol.23 , pp. 182-187
    • Shukla, A.1    Timblin, C.2    BeruBe, K.3    Gordon, T.4    McKinney, W.5    Driscoll, K.6    Vacek, P.7    Mossman, B.T.8
  • 66
    • 0030800795 scopus 로고    scopus 로고
    • Adenovector-mediated gene transfer of active transforming growth factor-beta 1 induces prolonged severe fibrosis in rat lung
    • Sime, P.J., Xing, Z., Graham, F.L., Csaky, K.G., and Gauldie, J. 1997. Adenovector-mediated gene transfer of active transforming growth factor-beta 1 induces prolonged severe fibrosis in rat lung. J. Clin. Invest. 100(4):768-776.
    • (1997) J. Clin. Invest , vol.100 , Issue.4 , pp. 768-776
    • Sime, P.J.1    Xing, Z.2    Graham, F.L.3    Csaky, K.G.4    Gauldie, J.5
  • 67
    • 27744542580 scopus 로고    scopus 로고
    • Trying to catch troublemakers with a metabolic profile
    • Sinha, G. 2005. Trying to catch troublemakers with a metabolic profile. Science 310:965-966.
    • (2005) Science , vol.310 , pp. 965-966
    • Sinha, G.1
  • 68
    • 0031201054 scopus 로고    scopus 로고
    • Fibroblasts as sentinel cells. synthesis of chemokines and regulation of inflammation
    • Smith, R.S., Smith, T.J., Blieden, T.M., and Phipps, R.P. 1997. Fibroblasts as sentinel cells. synthesis of chemokines and regulation of inflammation. Am. J. Pathol. 151:317-322.
    • (1997) Am. J. Pathol , vol.151 , pp. 317-322
    • Smith, R.S.1    Smith, T.J.2    Blieden, T.M.3    Phipps, R.P.4
  • 69
    • 0006648663 scopus 로고
    • The role of eicosanoids in transplant rejection
    • ed. R.R. Ruffolo and M.A. Hollinger, CRC Press Inc
    • Spurney, R.F., and Coffman, T.M. 1995. The role of eicosanoids in transplant rejection. In Inflammation Mediators and Pathways. ed. R.R. Ruffolo and M.A. Hollinger, 129-145. CRC Press Inc.
    • (1995) Inflammation Mediators and Pathways , pp. 129-145
    • Spurney, R.F.1    Coffman, T.M.2
  • 71
    • 0042839755 scopus 로고    scopus 로고
    • High-resolution magic angle spinning proton NMR analysis of human prostate tissue with slow spinning rates
    • Taylor, J.L., Wu, C.L., Cory, D., Gonzalez, R.G., Bielecki, A., and Cheng, L.L. 2003. High-resolution magic angle spinning proton NMR analysis of human prostate tissue with slow spinning rates. Magn. Reson. Med. 50:627-632.
    • (2003) Magn. Reson. Med , vol.50 , pp. 627-632
    • Taylor, J.L.1    Wu, C.L.2    Cory, D.3    Gonzalez, R.G.4    Bielecki, A.5    Cheng, L.L.6
  • 73
    • 0026848618 scopus 로고
    • Enhanced generation of free radicals from phagocytes induced by mineral dusts
    • Vallyathan, V., Mega, J.F., Shi, X., and Dalal, N.S. 1992. Enhanced generation of free radicals from phagocytes induced by mineral dusts. Am. J. Respir. Cell Mol. Biol. 6:404-413.
    • (1992) Am. J. Respir. Cell Mol. Biol , vol.6 , pp. 404-413
    • Vallyathan, V.1    Mega, J.F.2    Shi, X.3    Dalal, N.S.4
  • 74
    • 0023796649 scopus 로고    scopus 로고
    • Generation of free radicals from freshly fractured silica dust: Potential role in acute silica-induced lung injury
    • Vallyathan, V., Shi, X., Dalal, N., Irr, W., and Castranova, V. 1998. Generation of free radicals from freshly fractured silica dust: potential role in acute silica-induced lung injury. Am. Rev. Respir. Dis. 1213-1219.
    • (1998) Am. Rev. Respir. Dis , pp. 1213-1219
    • Vallyathan, V.1    Shi, X.2    Dalal, N.3    Irr, W.4    Castranova, V.5
  • 75
    • 0037331461 scopus 로고    scopus 로고
    • Formation of reactive oxygen species in rat epithelial cells upon simulation with fly ash
    • Voelkel, K., Krug, H.F., and Diabate, S. 2003. Formation of reactive oxygen species in rat epithelial cells upon simulation with fly ash. J. Biosci. 28:51-55.
    • (2003) J. Biosci , vol.28 , pp. 51-55
    • Voelkel, K.1    Krug, H.F.2    Diabate, S.3
  • 77
    • 0034775361 scopus 로고    scopus 로고
    • NMR and pattern recognition studies on the time-related metabolic effects of a-naphthylisothiocyanate on liver, urine, and plasma in the rat: An integrativemetabonomic approach
    • Waters, N.J., Holmes, E., Williams, A., Waterfield, C.J., Farrant, R.D., and Nicholson, J.K. 2001. NMR and pattern recognition studies on the time-related metabolic effects of a-naphthylisothiocyanate on liver, urine, and plasma in the rat: An integrativemetabonomic approach. Chem. Res. Toxicol. 14:1401-1412.
    • (2001) Chem. Res. Toxicol , vol.14 , pp. 1401-1412
    • Waters, N.J.1    Holmes, E.2    Williams, A.3    Waterfield, C.J.4    Farrant, R.D.5    Nicholson, J.K.6
  • 80
    • 84874791664 scopus 로고    scopus 로고
    • Wind, R.A., and Hu, J.Z. 2003.Magnetic susceptibility effects in nuclear magnetic resonance spectroscopy of biological objects. In Recent Res. Devel. Magnetism & Magnetic Mat., Recent Res. Devel. Magnetism & Magnetic Mat.. ed. S.G. Pandalai, 147-169.
    • Wind, R.A., and Hu, J.Z. 2003.Magnetic susceptibility effects in nuclear magnetic resonance spectroscopy of biological objects. In Recent Res. Devel. Magnetism & Magnetic Mat., vol. Recent Res. Devel. Magnetism & Magnetic Mat.. ed. S.G. Pandalai, 147-169.
  • 81
    • 45849092725 scopus 로고    scopus 로고
    • Method for high resolution magnetic resonance analysis using magic angle technique
    • US patents 665832 B2, 6670811, and 6836115 B2
    • Wind, R.A., and Hu, J.Z. 2004. Method for high resolution magnetic resonance analysis using magic angle technique. US patents 665832 B2, 6670811, and 6836115 B2.
    • (2004)
    • Wind, R.A.1    Hu, J.Z.2
  • 82
    • 84874790840 scopus 로고    scopus 로고
    • Wind, R.A., and Hu, J.Z. 2005. Proton NMR in biological objects submitted to magic angle spinning. In Encyclopedia of Analytical Science, 2nd Edition. ed. P.J.Worsfold, A. Townshend and C.F. Poole, 6:333-342. Elsevier, Oxford.
    • Wind, R.A., and Hu, J.Z. 2005. Proton NMR in biological objects submitted to magic angle spinning. In Encyclopedia of Analytical Science, 2nd Edition. ed. P.J.Worsfold, A. Townshend and C.F. Poole, 6:333-342. Elsevier, Oxford.
  • 83
    • 33846342538 scopus 로고    scopus 로고
    • 1H NMR in biological systems using low-speed magic angle spinning
    • 1H NMR in biological systems using low-speed magic angle spinning. Progr. Nucl. Magn. Reson. Spectr. 49:207-259.
    • (2006) Progr. Nucl. Magn. Reson. Spectr , vol.49 , pp. 207-259
    • Wind, R.A.1    Hu, J.Z.2
  • 84
    • 27244458364 scopus 로고    scopus 로고
    • Slow-MAS NMR: A new technology for in vivo metabolomic studies
    • Wind, R.A., Hu, J.Z., and Majors, P.D. 2005. Slow-MAS NMR: a new technology for in vivo metabolomic studies. Drug Discovery Today Technol. 2:291-294.
    • (2005) Drug Discovery Today Technol , vol.2 , pp. 291-294
    • Wind, R.A.1    Hu, J.Z.2    Majors, P.D.3
  • 85
  • 86
    • 0034905953 scopus 로고    scopus 로고
    • 1H NMR spectroscopy in organs and tissues using slow magic angle spinning
    • 1H NMR spectroscopy in organs and tissues using slow magic angle spinning. Magn. Reson. Med. 46:213-218.
    • (2001) Magn. Reson. Med , vol.46 , pp. 213-218
    • Wind, R.A.1    Hu, J.Z.2    Rommereim, D.N.3
  • 87
    • 0345600061 scopus 로고    scopus 로고
    • 1H NMR spectroscopy in a live mouse subjected to 1.5 Hz magic angle spinning
    • 1H NMR spectroscopy in a live mouse subjected to 1.5 Hz magic angle spinning. Magn. Reson. Med. 50:1113-1119.
    • (2003) Magn. Reson. Med , vol.50 , pp. 1113-1119
    • Wind, R.A.1    Hu, J.Z.2    Rommereim, D.N.3
  • 88
    • 45849117381 scopus 로고    scopus 로고
    • Advanced slow-magic angle spinning probe for magnetic resonance imaging and spectroscopy
    • US Patent 6653832 B2
    • Wind, R.A., Hu, J.Z., and Rommereim, D.N. 2006a. Advanced slow-magic angle spinning probe for magnetic resonance imaging and spectroscopy. US Patent 6653832 B2.
    • (2006)
    • Wind, R.A.1    Hu, J.Z.2    Rommereim, D.N.3
  • 89
    • 0028278029 scopus 로고
    • Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study
    • Zhang, K., Rekhter, M.D., Gordon, D., and Phan, S.H. 1994. Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis. A combined immunohistochemical and in situ hybridization study. Am. J. Pathol. 145:114-125.
    • (1994) Am. J. Pathol , vol.145 , pp. 114-125
    • Zhang, K.1    Rekhter, M.D.2    Gordon, D.3    Phan, S.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.