So what's the deal with metabonomics?

Analytical Chemistry

Volumn 75, Issue 17, 2003, Pages

  Lindon, John C ^a   Holmes, Elaine ^a   Nicholson, Jeremy K ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DATABASE SYSTEMS; DISEASES; NUCLEAR MAGNETIC RESONANCE;

BIOFLUIDS;

METABOLISM;

CELL COMPOSITION; CELL METABOLISM; CELL TYPE; CHEMOMETRIC ANALYSIS; DRUG RESEARCH; DRUG SAFETY; DRUG TOXICITY; HUMAN; IONIZATION; METABOLOMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; REVIEW; TECHNIQUE;

ANIMALS; DISEASE; GENOMICS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; METABOLISM;

EID: 0042338519     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. Sinclair, B. The Scientist 1999, 13, 18-20.
2. Geisow, M. J. Nat. Biotechnol. 1998, 16, 206.
3. Nicholson, J. K.; Lindon, J. C.; Holmes, E. Xenobiotica 1999, 29, 1181-1189.
4. Nicholson, J. K.; Connelly, J.; Lindon, J. C.; Holmes, E. Nat. Rev. Drug Discovery 2002, 1, 153-161.
5. Derr, R. E Biochem. Archives 1985, 1, 239-247.
6. Raamsdonk, L. M.; et al. Nature Biotech. 2001, 19, 45-50.
7. Nicholson, J. K.; Wilson, I. D. Prog. NMR Spectrosc. 1989, 21, 444-501.
8. Lindon, J. C.; Nicholson, J. K.; Wilson, I. D. J. Chromatogr B. 2000, 748, 233-258.
9. Garrod, S. L.; et al. Magn. Reson. Med. 1999, 41, 1108-1118.
10. Cheng, L. L.; et al. Magn. Reson. Med. 1996, 36, 653-658.
11. Tomlins, A.; et al. Anal. Comm. 1998, 35, 113-115.
12. Wider, G. Biotechniques 2000, 29, 1278-1294.
13. Jacoby, E.; Davies, J.; Blommers, M. J. J. Curr. Top. Med. Chem. 2003, 3, 11-23.
14. Srivastava, S.; Govil, G, Curr. Drg. Chem. 2001, 5, 1039-1057.
15. Moore, J. M. Biopolymers 1999, 51, 221-243.
16. Lindon, J. C.; Holmes, E.; Nicholson, J. K. Prog. NMR Spectrosc. 2001, 39, 1-40.
17. Holmes, E.; et al. NMR Biomed. 1998, 11, 235-244.
18. Brown, T. R.; Stoyanova, R. J. Magn. Reson. 1996, 112, 32-43.
19. Farrant, R. D.; Lindon, J. C.; Rahr, E.; Sweatman, B. C. J. Pharm. Biomed. Anal. 1992, 10, 141-144.
20. Holmes, E.; Nicholson, J. K.; Tranter, G. Chem. Res. Toxicol. 2001, 14, 182-191.
21. Holmes, E.; et al. Chemom. Intell. Lab. Syst. 1998, 44, 245-255.
22. Holmes, E.; et al. Chem. Res. Toxicol. 2000, 13, 471-478.
23. Garrod, S.; et al. Magn. Reson. Med. 2001, 45, 781-790.
24. Waters, N. J.; et al. Chem. Res. Toxicol. 2001, 14, 1401-1412.
25. Lindon, J. C.; et al. Toxicol. Appl. Pharmacol. 2003, 187, 137-146.
26. Keun, H. C.; et al. Chem. Res. Toxicol. 2002, 15, 1380-1386.
27. Phalaraksh, C.; et al. Insect Biochem. Mol. Biol. 1999, 29, 795-805.
28. Bundy, J. G.; et al. Environ. Toxicol. Chem. 2002, 21, 1966-1972.
29. Griffin, J. L.; Walker, L.; Shore, R. F.; Nicholson, J. K. Xenobiotica 2001, 31, 377-385.
30. Howells, S. L.; Maxwell, R. J.; Peet, A. C.; Griffiths, J. R. Magn. Reson. Med. 1992, 28, 214-236.
31. Holmes, E.; et al. Anal. Biochem. 1994, 220, 284-296.
32. Kruse, S.; Kvalheim, O. M.; Gadeholt, G.; Halsteinslid, L.; Sletten, E. Chemom. Intel. Lab. Syst. 1991, 11, 191-196.
33. Brindle, J. T.; et al. Nat. Med. 2002, 8, 1439-1445.
34. Lindon, J. C.; Nicholson, J. K.; Everett, J. R. Ann. Rep. NMR Spectrosc. 1999, 38, 1-88.