메뉴 건너뛰기




Volumn 12, Issue 1, 2008, Pages

Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CALGRANULIN; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN S 100; ADVANCED GLYCOSYLATION END PRODUCT RECEPTOR; ADVANCED GLYCOSYLATION END-PRODUCT RECEPTOR; IMMUNOGLOBULIN RECEPTOR;

EID: 45549107924     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc6164     Document Type: Review
Times cited : (114)

References (81)
  • 2
    • 0037451929 scopus 로고    scopus 로고
    • The epidemiology of sepsis in the United States from 1979 through 2000
    • 10.1056/NEJMoa022139 12700374
    • Martin GS Mannino DM Eaton S Moss M The epidemiology of sepsis in the United States from 1979 through 2000 N Engl J Med 2003, 348:1546-1554. 10.1056/NEJMoa022139 12700374
    • (2003) N Engl J Med , vol.348 , pp. 1546-1554
    • Martin, G.S.1    Mannino, D.M.2    Eaton, S.3    Moss, M.4
  • 3
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • 10.1038/35021228 10963608
    • Aderem A Ulevitch RJ Toll-like receptors in the induction of the innate immune response Nature 2000, 406:782-787. 10.1038/35021228 10963608
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 4
    • 0031225997 scopus 로고    scopus 로고
    • Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts
    • 9278290
    • Vely F Vivier E Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts J Immunol 1997, 159:2075-2077. 9278290
    • (1997) J Immunol , vol.159 , pp. 2075-2077
    • Vely, F.1    Vivier, E.2
  • 5
    • 0037805700 scopus 로고    scopus 로고
    • TREMs in the immune system and beyond
    • 10.1038/nri1106 12776204
    • Colonna M TREMs in the immune system and beyond Nat Rev Immunol 2003, 3:445-453. 10.1038/nri1106 12776204
    • (2003) Nat Rev Immunol , vol.3 , pp. 445-453
    • Colonna, M.1
  • 7
    • 0038578608 scopus 로고    scopus 로고
    • Novel strategies for the treatment of sepsis
    • 10.1038/nm0503-517 12724763
    • Riedemann NC Guo RF Ward PA Novel strategies for the treatment of sepsis Nat Med 2003, 9:517-524. 10.1038/nm0503-517 12724763
    • (2003) Nat Med , vol.9 , pp. 517-524
    • Riedemann, N.C.1    Guo, R.F.2    Ward, P.A.3
  • 8
    • 0028319060 scopus 로고
    • Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: Implications for human disease
    • 10.1083/jcb.126.1.111 7517942
    • Lisanti MP Scherer PE Vidugiriene J Tang Z Hermanowski-Vosatka A Tu YH Cook RF Sargiacomo M et al.: Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: Implications for human disease J Cell Biol 1994, 126:111-126. 10.1083/jcb.126.1.111 7517942
    • (1994) J Cell Biol , vol.126 , pp. 111-126
    • Lisanti, M.P.1    Scherer, P.E.2    Vidugiriene, J.3    Tang, Z.4    Hermanowski-Vosatka, A.5    Tu, Y.H.6    Cook, R.F.7    Sargiacomo, M.8
  • 10
    • 0026650438 scopus 로고
    • Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface
    • 1321822
    • Schmidt AM Vianna M Gerlach M Brett J Ryan J Kao J Esposito C Hegarty H Hurley W Clauss M et al.: Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface J Biol Chem 1992, 267:14987-14997. 1321822
    • (1992) J Biol Chem , vol.267 , pp. 14987-14997
    • Schmidt, A.M.1    Vianna, M.2    Gerlach, M.3    Brett, J.4    Ryan, J.5    Kao, J.6    Esposito, C.7    Hegarty, H.8    Hurley, W.9    Clauss, M.10
  • 11
    • 1542330107 scopus 로고    scopus 로고
    • Receptor for advanced glycation end-products is a marker of type I lung alveolar cells
    • 10.1111/j.1356-9597.2004.00712.x 15009093
    • Shirasawa M Fujiwara N Hirabayashi S Ohno H Iida J Makita K Hata Y Receptor for advanced glycation end-products is a marker of type I lung alveolar cells Genes Cells 2004, 9:165-174. 10.1111/ j.1356-9597.2004.00712.x 15009093
    • (2004) Genes Cells , vol.9 , pp. 165-174
    • Shirasawa, M.1    Fujiwara, N.2    Hirabayashi, S.3    Ohno, H.4    Iida, J.5    Makita, K.6    Hata, Y.7
  • 12
    • 0031577596 scopus 로고    scopus 로고
    • Type II alveolar epithelial cells in lung express receptor for advanced glycation end products (RAGE) gene
    • 10.1006/bbrc.1997.7263 9299542
    • Katsuoka F Kawakami Y Arai T Imuta H Fujiwara M Kanma H Yamashita K Type II alveolar epithelial cells in lung express receptor for advanced glycation end products (RAGE) gene Biochem Biophys Res Commun 1997, 238:512-516. 10.1006/bbrc.1997.7263 9299542
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 512-516
    • Katsuoka, F.1    Kawakami, Y.2    Arai, T.3    Imuta, H.4    Fujiwara, M.5    Kanma, H.6    Yamashita, K.7
  • 13
    • 0142122366 scopus 로고    scopus 로고
    • Tissue-specific expression patterns of the RAGE receptor and its soluble forms-a result of regulated alternative splicing?
    • 14580673
    • Schlueter C Hauke S Flohr AM Rogalla P Bullerdiek J Tissue-specific expression patterns of the RAGE receptor and its soluble forms-a result of regulated alternative splicing? Biochim Biophys Acta 2003, 1630:1-6. 14580673
    • (2003) Biochim Biophys Acta , vol.1630 , pp. 1-6
    • Schlueter, C.1    Hauke, S.2    Flohr, A.M.3    Rogalla, P.4    Bullerdiek, J.5
  • 16
    • 0033538569 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways
    • 10.1074/jbc.274.28.19919 10391939
    • Huttunen HJ Fages C Rauvala H Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways J Biol Chem 1999, 274:19919-19924. 10.1074/ jbc.274.28.19919 10391939
    • (1999) J Biol Chem , vol.274 , pp. 19919-19924
    • Huttunen, H.J.1    Fages, C.2    Rauvala, H.3
  • 17
    • 4244040278 scopus 로고    scopus 로고
    • Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: Involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors
    • 10.1016/S0009-2797(97)00157-9 9679550
    • Thornalley PJ Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: Involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors Chem Biol Interact 1998, 111:137-151. 10.1016/S0009-2797(97)00157-9 9679550
    • (1998) Chem Biol Interact , vol.111 , pp. 137-151
    • Thornalley, P.J.1
  • 19
    • 0342646984 scopus 로고    scopus 로고
    • Interaction of the receptor for advanced glycation end products (RAGE) with transthyretin triggers nuclear transcription factor kB (NF-kB) activation
    • 10908156
    • Sousa MM Yan SD Stern D Saraiva MJ Interaction of the receptor for advanced glycation end products (RAGE) with transthyretin triggers nuclear transcription factor kB (NF-kB) activation Lab Invest 2000, 80:1101-1110. 10908156
    • (2000) Lab Invest , vol.80 , pp. 1101-1110
    • Sousa, M.M.1    Yan, S.D.2    Stern, D.3    Saraiva, M.J.4
  • 20
    • 0035911959 scopus 로고    scopus 로고
    • The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells
    • 10.1083/jcb.152.6.1197 11257120
    • Degryse B Bonaldi T Scaffidi P Muller S Resnati M Sanvito F Arrigoni G Bianchi ME The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells J Cell Biol 2001, 152:1197-1206. 10.1083/jcb.152.6.1197 11257120
    • (2001) J Cell Biol , vol.152 , pp. 1197-1206
    • Degryse, B.1    Bonaldi, T.2    Scaffidi, P.3    Muller, S.4    Resnati, M.5    Sanvito, F.6    Arrigoni, G.7    Bianchi, M.E.8
  • 21
    • 5644256969 scopus 로고    scopus 로고
    • RAGE (receptor for advanced glycation end products): A central player in the inflammatory response
    • 10.1016/j.micinf.2004.08.004 15488742
    • Chavakis T Bierhaus A Nawroth PP RAGE (receptor for advanced glycation end products): A central player in the inflammatory response Microbes Infect 2004, 6:1219-1225. 10.1016/j.micinf.2004.08.004 15488742
    • (2004) Microbes Infect , vol.6 , pp. 1219-1225
    • Chavakis, T.1    Bierhaus, A.2    Nawroth, P.P.3
  • 22
    • 0030910830 scopus 로고    scopus 로고
    • Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products
    • 10.1074/jbc.272.26.16498 9195959
    • Li J Schmidt AM Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products J Biol Chem 1997, 272:16498-16506. 10.1074/jbc.272.26.16498 9195959
    • (1997) J Biol Chem , vol.272 , pp. 16498-16506
    • Li, J.1    Schmidt, A.M.2
  • 23
    • 3042513726 scopus 로고    scopus 로고
    • Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells
    • 15239215
    • Takada M Hirata K Ajiki T Suzuki Y Kuroda Y Expression of receptor for advanced glycation end products (RAGE) and MMP-9 in human pancreatic cancer cells Hepatogastroenterology 2004, 51:928-930. 15239215
    • (2004) Hepatogastroenterology , vol.51 , pp. 928-930
    • Takada, M.1    Hirata, K.2    Ajiki, T.3    Suzuki, Y.4    Kuroda, Y.5
  • 24
    • 0032741165 scopus 로고    scopus 로고
    • cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein
    • 10.1016/S0169-328X(99)00174-6 10521570
    • Malherbe P Richards JG Gaillard H Thompson A Diener C Schuler A Huber G cDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein Brain Res Mol Brain Res 1999, 71:159-170. 10.1016/S0169-328X(99)00174-6 10521570
    • (1999) Brain Res Mol Brain Res , vol.71 , pp. 159-170
    • Malherbe, P.1    Richards, J.G.2    Gaillard, H.3    Thompson, A.4    Diener, C.5    Schuler, A.6    Huber, G.7
  • 25
    • 0027957087 scopus 로고
    • Three genes in the human MHC class III region near the junction with the class II: Gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3
    • 10.1006/geno.1994.1517 7835890
    • Sugaya K Fukagawa T Matsumoto K Mita K Takahashi E Ando A Inoko H Ikemura T Three genes in the human MHC class III region near the junction with the class II: Gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3 Genomics 1994, 23:408-419. 10.1006/ geno.1994.1517 7835890
    • (1994) Genomics , vol.23 , pp. 408-419
    • Sugaya, K.1    Fukagawa, T.2    Matsumoto, K.3    Mita, K.4    Takahashi, E.5    Ando, A.6    Inoko, H.7    Ikemura, T.8
  • 26
    • 0033603241 scopus 로고    scopus 로고
    • RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
    • 10.1016/S0092-8674(00)80801-6 10399917
    • Hofmann MA Drury S Fu C Qu W Taguchi A Lu Y Avila C Kambham N Bierhaus A Nawroth P et al.: RAGE mediates a noveA proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides Cell 1999, 97:889-901. 10.1016/S0092-8674(00)80801-6 10399917
    • (1999) Cell , vol.97 , pp. 889-901
    • Hofmann, M.A.1    Drury, S.2    Fu, C.3    Qu, W.4    Taguchi, A.5    Lu, Y.6    Avila, C.7    Kambham, N.8    Bierhaus, A.9    Nawroth, P.10
  • 27
    • 0142039004 scopus 로고    scopus 로고
    • The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site
    • 10.1016/S0014-5793(03)00846-9 12935895
    • Ishihara K Tsutsumi K Kawane S Nakajima M Kasaoka T The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site FEBS Lett 2003, 550:107-113. 10.1016/ S0014-5793(03)00846-9 12935895
    • (2003) FEBS Lett , vol.550 , pp. 107-113
    • Ishihara, K.1    Tsutsumi, K.2    Kawane, S.3    Nakajima, M.4    Kasaoka, T.5
  • 28
    • 9644302477 scopus 로고    scopus 로고
    • Purification and characterization of mouse soluble receptor for advanced glycation end products (sRAGE)
    • 1868562 15381690 10.1074/jbc.M409782200
    • Hanford LE Enghild JJ Valnickova Z Petersen SV Schaefer LM Schaefer TM Reinhart TA Oury TD Purification and characterization of mouse soluble receptor for advanced glycation end products (sRAGE) J Biol Chem 2004, 279:50019-50024. 1868562 15381690 10.1074/jbc.M409782200
    • (2004) J Biol Chem , vol.279 , pp. 50019-50024
    • Hanford, L.E.1    Enghild, J.J.2    Valnickova, Z.3    Petersen, S.V.4    Schaefer, L.M.5    Schaefer, T.M.6    Reinhart, T.A.7    Oury, T.D.8
  • 29
    • 3242716769 scopus 로고    scopus 로고
    • RAGE: A new pleiotropic antagonistic gene?
    • 10.1196/annals.1297.038 15247020
    • Simm A Bartling B Silber RE RAGE: A new pleiotropic antagonistic gene? Ann N Y Acad Sci 2004, 1019:228-231. 10.1196/annals.1297.038 15247020
    • (2004) Ann N Y Acad Sci , vol.1019 , pp. 228-231
    • Simm, A.1    Bartling, B.2    Silber, R.E.3
  • 30
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
    • 10.1074/jbc.270.43.25752 7592757
    • Hori O Brett J Slattery T Cao R Zhang J Chen JX Nagashima M Lundh ER Vijay S Nitecki D et al.: The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system J Biol Chem 1995, 270:25752-25761. 10.1074/ jbc.270.43.25752 7592757
    • (1995) J Biol Chem , vol.270 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3    Cao, R.4    Zhang, J.5    Chen, J.X.6    Nagashima, M.7    Lundh, E.R.8    Vijay, S.9    Nitecki, D.10
  • 31
    • 0000920292 scopus 로고    scopus 로고
    • Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease
    • 24672 9144231 10.1073/pnas.94.10.5296
    • Du Yan S Zhu H Fu J Yan SF Roher A Tourtellotte WW Rajavashisth T Chen X Godman GC Stern D et al.: Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease Proc Natl Acad Sci U S A 1997, 94:5296-5301. 24672 9144231 10.1073/pnas.94.10.5296
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 5296-5301
    • Du Yan, S.1    Zhu, H.2    Fu, J.3    Yan, S.F.4    Roher, A.5    Tourtellotte, W.W.6    Rajavashisth, T.7    Chen, X.8    Godman, G.C.9    Stern, D.10
  • 33
    • 10744229528 scopus 로고    scopus 로고
    • The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: A novel pathway for inflammatory cell recruitment
    • 10.1084/jem.20030800 14623906 2194124
    • Chavakis T Bierhaus A Al-Fakhri N Schneider D Witte S Linn T Nagashima M Morser J Arnold B Preissner KT et al.: The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: A novel pathway for inflammatory cell recruitment J Exp Med 2003, 198:1507-1515. 10.1084/ jem.20030800 14623906 2194124
    • (2003) J Exp Med , vol.198 , pp. 1507-1515
    • Chavakis, T.1    Bierhaus, A.2    Al-Fakhri, N.3    Schneider, D.4    Witte, S.5    Linn, T.6    Nagashima, M.7    Morser, J.8    Arnold, B.9    Preissner, K.T.10
  • 34
    • 0037189083 scopus 로고    scopus 로고
    • Advanced glycation end products (AGE) and their receptor (RAGE) in the brain of patients with Creutzfeldt-Jakob disease with prion plaques
    • 10.1016/S0304-3940(02)00310-5 12057842
    • Sasaki N Takeuchi M Chowei H Kikuchi S Hayashi Y Nakano N Ikeda H Yamagishi S Kitamoto T Saito T et al.: Advanced glycation end products (AGE) and their receptor (RAGE) in the brain of patients with Creutzfeldt-Jakob disease with prion plaques Neurosci Lett 2002, 326:117-120. 10.1016/S0304-3940(02)00310-5 12057842
    • (2002) Neurosci Lett , vol.326 , pp. 117-120
    • Sasaki, N.1    Takeuchi, M.2    Chowei, H.3    Kikuchi, S.4    Hayashi, Y.5    Nakano, N.6    Ikeda, H.7    Yamagishi, S.8    Kitamoto, T.9    Saito, T.10
  • 36
    • 0033615356 scopus 로고    scopus 로고
    • N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression
    • 10.1074/jbc.274.44.31740 10531386
    • Kislinger T Fu C Huber B Qu W Taguchi A Du Yan S Hofmann M Yan SF Pischetsrieder M Stern D et al.: N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression J Biol Chem 1999, 274:31740-31749. 10.1074/jbc.274.44.31740 10531386
    • (1999) J Biol Chem , vol.274 , pp. 31740-31749
    • Kislinger, T.1    Fu, C.2    Huber, B.3    Qu, W.4    Taguchi, A.5    Du Yan, S.6    Hofmann, M.7    Yan, S.F.8    Pischetsrieder, M.9    Stern, D.10
  • 37
    • 0032694683 scopus 로고    scopus 로고
    • The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: A mechanism for producing advanced glycation end products at sites of inflammation
    • 408396 10393704 10.1172/JCI3042
    • Anderson MM Requena JR Crowley JR Thorpe SR Heinecke JW The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: A mechanism for producing advanced glycation end products at sites of inflammation J Clin Invest 1999, 104:103-113. 408396 10393704 10.1172/JCI3042
    • (1999) J Clin Invest , vol.104 , pp. 103-113
    • Anderson, M.M.1    Requena, J.R.2    Crowley, J.R.3    Thorpe, S.R.4    Heinecke, J.W.5
  • 38
    • 0000746938 scopus 로고    scopus 로고
    • Cell activation by glycated proteins. AGE receptors, receptor recognition factors and functional classification of AGEs
    • 9846883
    • Thornalley PJ Cell activation by glycated proteins. AGE receptors, receptor recognition factors and functional classification of AGEs Cell Mol Biol (Noisy-le-grand) 1998, 44:1013-1023. 9846883
    • (1998) Cell Mol Biol (Noisy-le-grand) , vol.44 , pp. 1013-1023
    • Thornalley, P.J.1
  • 39
    • 0030859290 scopus 로고    scopus 로고
    • Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress
    • 10.1074/jbc.272.28.17810 9211935
    • Lander HM Tauras JM Ogiste JS Hori O Moss RA Schmidt AM Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress J Biol Chem 1997, 272:17810-17814. 10.1074/ jbc.272.28.17810 9211935
    • (1997) J Biol Chem , vol.272 , pp. 17810-17814
    • Lander, H.M.1    Tauras, J.M.2    Ogiste, J.S.3    Hori, O.4    Moss, R.A.5    Schmidt, A.M.6
  • 41
    • 2442631329 scopus 로고    scopus 로고
    • Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells
    • 10.2337/diabetes.46.9.1481 9287050
    • Bierhaus A Chevion S Chevion M Hofmann M Quehenberger P Illmer T Luther T Berentshtein E Tritschler H Muller M Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells Diabetes 1997, 46:1481-1490. 10.2337/ diabetes.46.9.1481 9287050
    • (1997) Diabetes , vol.46 , pp. 1481-1490
    • Bierhaus, A.1    Chevion, S.2    Chevion, M.3    Hofmann, M.4    Quehenberger, P.5    Illmer, T.6    Luther, T.7    Berentshtein, E.8    Tritschler, H.9    Muller, M.10
  • 42
    • 2442645301 scopus 로고    scopus 로고
    • Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding
    • 416409 15143181 10.1128/MCB.24.11.4880-4894.2004
    • Sorci G Riuzzi F Arcuri C Giambanco I Donato R Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding Mol Cell Biol 2004, 24:4880-4894. 416409 15143181 10.1128/MCB.24.11.4880-4894.2004
    • (2004) Mol Cell Biol , vol.24 , pp. 4880-4894
    • Sorci, G.1    Riuzzi, F.2    Arcuri, C.3    Giambanco, I.4    Donato, R.5
  • 44
    • 0035096603 scopus 로고    scopus 로고
    • Role of receptor for advanced glycation end-product (RAGE) and the JAK/ STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells
    • 10.1002/1097-4644(20010401)81:1<102::AID-JCB1027>3.0.CO;2-Y 11180401
    • Huang JS Guh JY Chen HC Hung WC Lai YH Chuang LY Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells J Cell Biochem 2001, 81:102-113. 10.1002/ 1097-4644(20010401)81:1<102::AID-JCB1027>3.0.CO;2-Y 11180401
    • (2001) J Cell Biochem , vol.81 , pp. 102-113
    • Huang, J.S.1    Guh, J.Y.2    Chen, H.C.3    Hung, W.C.4    Lai, Y.H.5    Chuang, L.Y.6
  • 45
    • 4444371768 scopus 로고    scopus 로고
    • S100 proteins in mouse and man: From evolution to function and pathology (including an update of the nomenclature)
    • 10.1016/j.bbrc.2004.07.096 15336958
    • Marenholz I Heizmann CW Fritz G S100 proteins in mouse and man: From evolution to function and pathology (including an update of the nomenclature) Biochem Biophys Res Commun 2004, 322:1111-1122. 10.1016/ j.bbrc.2004.07.096 15336958
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 1111-1122
    • Marenholz, I.1    Heizmann, C.W.2    Fritz, G.3
  • 46
    • 0034995073 scopus 로고    scopus 로고
    • S100: A multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles
    • 10.1016/S1357-2725(01)00046-2 11390274
    • Donato R S100: A multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles Int J Biochem Cell Biol 2001, 33:637-668. 10.1016/S1357-2725(01)00046-2 11390274
    • (2001) Int J Biochem Cell Biol , vol.33 , pp. 637-668
    • Donato, R.1
  • 47
    • 0029669991 scopus 로고    scopus 로고
    • The S100 family of EF-hand calcium-binding proteins: Functions and pathology
    • 8701470
    • Schafer BW Heinzmann CW The S100 family of EF-hand calcium-binding proteins: Functions and pathology Trends Biochem Sci 1996, 21:134-140. 8701470
    • (1996) Trends Biochem Sci , vol.21 , pp. 134-140
    • Schafer, B.W.1    Heinzmann, C.W.2
  • 48
    • 0037351507 scopus 로고    scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system
    • 10.1038/nm831 12598893
    • Yan SSD Wu ZY Zhang HP Furtado G Chen X Yan SF Schmidt AM Brown C Stern A LaFaille J et al.: Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system Nat Med 2003, 9:287-293. 10.1038/nm831 12598893
    • (2003) Nat Med , vol.9 , pp. 287-293
    • Yan, S.S.D.1    Wu, Z.Y.2    Zhang, H.P.3    Furtado, G.4    Chen, X.5    Yan, S.F.6    Schmidt, A.M.7    Brown, C.8    Stern, A.9    LaFaille, J.10
  • 49
    • 1242272130 scopus 로고    scopus 로고
    • S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE)
    • 10.1074/jbc.M310124200 14617629
    • Arumugam T Simeone DM Schmidt AM Logsdon CD S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE) J Biol Chem 2004, 279:5059-5065. 10.1074/jbc.M310124200 14617629
    • (2004) J Biol Chem , vol.279 , pp. 5059-5065
    • Arumugam, T.1    Simeone, D.M.2    Schmidt, A.M.3    Logsdon, C.D.4
  • 50
    • 0034704068 scopus 로고    scopus 로고
    • Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation
    • 10.1074/jbc.M006993200 11007787
    • Huttunen HJ Kuja-Panula J Sorci G Agneletti AL Donato R Rauvala H Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation J Biol Chem 2000, 275:40096-40105. 10.1074/ jbc.M006993200 11007787
    • (2000) J Biol Chem , vol.275 , pp. 40096-40105
    • Huttunen, H.J.1    Kuja-Panula, J.2    Sorci, G.3    Agneletti, A.L.4    Donato, R.5    Rauvala, H.6
  • 51
    • 0034011049 scopus 로고    scopus 로고
    • Neuron-specific enolase as a marker of fatal outcome in patients with severe sepsis or septic shock
    • 10.1097/00000542-200003000-00057 10719986
    • Weigand MA Volkmann M Schmidt H Martin E Bohrer H Bardenheuer HJ Neuron-specific enolase as a marker of fatal outcome in patients with severe sepsis or septic shock Anesthesiology 2000, 92:905-907. 10.1097/ 00000542-200003000-00057 10719986
    • (2000) Anesthesiology , vol.92 , pp. 905-907
    • Weigand, M.A.1    Volkmann, M.2    Schmidt, H.3    Martin, E.4    Bohrer, H.5    Bardenheuer, H.J.6
  • 52
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • 10.1038/nri1594 15803152
    • Lotze MT Tracey KJ High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal Nat Rev Immunol 2005, 5:331-342. 10.1038/ nri1594 15803152
    • (2005) Nat Rev Immunol , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 53
    • 0023646017 scopus 로고
    • Isolation and some characteristics of an adhesive factor of brain that enhances neurite outgrowth in central neurons
    • 3680268
    • Rauvala H Pihlaskari R Isolation and some characteristics of an adhesive factor of brain that enhances neurite outgrowth in central neurons J Biol Chem 1987, 262:16625-16635. 3680268
    • (1987) J Biol Chem , vol.262 , pp. 16625-16635
    • Rauvala, H.1    Pihlaskari, R.2
  • 54
    • 0024202114 scopus 로고
    • The adhesive and neurite-promoting molecule p30: Analysis of the amino terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons
    • 10.1083/jcb.107.6.2293 2461949
    • Rauvala H Merenmies J Pihlaskari R Korkolainen M Huhtala ML Panula P The adhesive and neurite-promoting molecule p30: Analysis of the amino terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons J Cell Biol 1988, 107:2293-2305. 10.1083/jcb.107.6.2293 2461949
    • (1988) J Cell Biol , vol.107 , pp. 2293-2305
    • Rauvala, H.1    Merenmies, J.2    Pihlaskari, R.3    Korkolainen, M.4    Huhtala, M.L.5    Panula, P.6
  • 56
  • 57
    • 0037177825 scopus 로고    scopus 로고
    • Novel signal transduction pathway utilized by extracellular HSP70: Role of toll-like receptor (TLR) 2 and TLR4
    • 10.1074/jbc.M200497200 11836257
    • Asea A Rehli M Kabingu E Boch JA Bare O Auron PE Stevenson MA Calderwood SK Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4 J Biol Chem 2002, 277:15028-15034. 10.1074/jbc.M200497200 11836257
    • (2002) J Biol Chem , vol.277 , pp. 15028-15034
    • Asea, A.1    Rehli, M.2    Kabingu, E.3    Boch, J.A.4    Bare, O.5    Auron, P.E.6    Stevenson, M.A.7    Calderwood, S.K.8
  • 58
    • 0038156223 scopus 로고    scopus 로고
    • ATP gradients inhibit the migratory capacity of specific human dendritic cell types: Implications for P2Y11 receptor signaling
    • 10.1182/blood-2002-12-3745 12649135
    • Schnurr M Toy T Stoitzner P Cameron P Shin A Beecroft T Davis ID Cebon J Maraskovsky E ATP gradients inhibit the migratory capacity of specific human dendritic cell types: Implications for P2Y11 receptor signaling Blood 2003, 102:613-620. 10.1182/blood-2002-12-3745 12649135
    • (2003) Blood , vol.102 , pp. 613-620
    • Schnurr, M.1    Toy, T.2    Stoitzner, P.3    Cameron, P.4    Shin, A.5    Beecroft, T.6    Davis, I.D.7    Cebon, J.8    Maraskovsky, E.9
  • 59
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • 10.1038/nature01991 14520412
    • Shi Y Evans JE Rock KL Molecular identification of a danger signal that alerts the immune system to dying cells Nature 2003, 425:516-521. 10.1038/nature01991 14520412
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3
  • 60
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • 10.1038/nature00858 12110890
    • Scaffidi P Misteli T Bianchi ME Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Nature 2002, 418:191-195. 10.1038/ nature00858 12110890
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 61
    • 0037102393 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis
    • 12183440
    • Huttunen HJ Fages C Kuja-Panula J Ridley AJ Rauvala H Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis Cancer Res 2002, 62:4805-4811. 12183440
    • (2002) Cancer Res , vol.62 , pp. 4805-4811
    • Huttunen, H.J.1    Fages, C.2    Kuja-Panula, J.3    Ridley, A.J.4    Rauvala, H.5
  • 63
    • 20944436774 scopus 로고    scopus 로고
    • The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism
    • 1077171 15841214 10.1172/JCI200522782
    • Abeyama K Stern DM Ito Y Kawahara K Yoshimoto Y Tanaka M Uchimura T Ida N Yamazaki Y Yamada S et al.: The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism J Clin Invest 2005, 115:1267-1274. 1077171 15841214 10.1172/ JCI200522782
    • (2005) J Clin Invest , vol.115 , pp. 1267-1274
    • Abeyama, K.1    Stern, D.M.2    Ito, Y.3    Kawahara, K.4    Yoshimoto, Y.5    Tanaka, M.6    Uchimura, T.7    Ida, N.8    Yamazaki, Y.9    Yamada, S.10
  • 66
    • 0036724929 scopus 로고    scopus 로고
    • HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice
    • 10.1053/gast.2002.35391 12198705
    • Sappington PL Yang R Yang H Tracey KJ Delude RL Fink MP HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice Gastroenterology 2002, 123:790-802. 10.1053/gast.2002.35391 12198705
    • (2002) Gastroenterology , vol.123 , pp. 790-802
    • Sappington, P.L.1    Yang, R.2    Yang, H.3    Tracey, K.J.4    Delude, R.L.5    Fink, M.P.6
  • 68
    • 1542380035 scopus 로고    scopus 로고
    • Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
    • 10.1074/jbc.M306793200 14660645
    • Park JS Svetkauskaite D He Q Kim JY Strassheim D Ishizaka A Abraham E Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein J Biol Chem 2004, 279:7370-7377. 10.1074/jbc.M306793200 14660645
    • (2004) J Biol Chem , vol.279 , pp. 7370-7377
    • Park, J.S.1    Svetkauskaite, D.2    He, Q.3    Kim, J.Y.4    Strassheim, D.5    Ishizaka, A.6    Abraham, E.7
  • 70
    • 20244373939 scopus 로고    scopus 로고
    • The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
    • 10.1084/jem.20042614 15795240 2213120
    • Tsung A Sahai R Tanaka H Nakao A Fink MP Lotze MT Yang H Li J Tracey KJ Geller DA et al.: The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion J Exp Med 2005, 201:1135-1143. 10.1084/ jem.20042614 15795240 2213120
    • (2005) J Exp Med , vol.201 , pp. 1135-1143
    • Tsung, A.1    Sahai, R.2    Tanaka, H.3    Nakao, A.4    Fink, M.P.5    Lotze, M.T.6    Yang, H.7    Li, J.8    Tracey, K.J.9    Geller, D.A.10
  • 76
    • 10744229479 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice
    • 10.1002/hep.20045 14767995
    • Zeng S Feirt N Goldstein M Guarrera J Ippagunta N Ekong U Dun H Lu Y Qu W Schmidt AM et al.: Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice Hepatology 2004, 39:422-432. 10.1002/hep.20045 14767995
    • (2004) Hepatology , vol.39 , pp. 422-432
    • Zeng, S.1    Feirt, N.2    Goldstein, M.3    Guarrera, J.4    Ippagunta, N.5    Ekong, U.6    Dun, H.7    Lu, Y.8    Qu, W.9    Schmidt, A.M.10
  • 77
    • 13644264763 scopus 로고    scopus 로고
    • RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB
    • 10.1084/jem.20040934 15699076 2213026
    • Cataldegirmen G Zeng S Feirt N Ippagunta N Dun H Qu W Lu Y Rong LL Hofmann MA Kislinger T et al.: RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB J Exp Med 2005, 201:473-484. 10.1084/jem.20040934 15699076 2213026
    • (2005) J Exp Med , vol.201 , pp. 473-484
    • Cataldegirmen, G.1    Zeng, S.2    Feirt, N.3    Ippagunta, N.4    Dun, H.5    Qu, W.6    Lu, Y.7    Rong, L.L.8    Hofmann, M.A.9    Kislinger, T.10
  • 78
    • 3042668028 scopus 로고    scopus 로고
    • Enhanced expression of receptor for advanced glycation end products in chronic kidney disease
    • 10.1097/01.ASN.0000131526.99506.F7 15213278
    • Hou FF Ren H Owen WF Jr Guo ZJ Chen PY Schmidt AM Miyata T Zhang X Enhanced expression of receptor for advanced glycation end products in chronic kidney disease J Am Soc Nephrol 2004, 15:1889-1896. 10.1097/ 01.ASN.0000131526.99506.F7 15213278
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1889-1896
    • Hou, F.F.1    Ren, H.2    Owen Jr., W.F.3    Guo, Z.J.4    Chen, P.Y.5    Schmidt, A.M.6    Miyata, T.7    Zhang, X.8
  • 79
    • 0035653506 scopus 로고    scopus 로고
    • Characterization of allelic and nucleotide variation between the RAGE gene on chromosome 6 and a homologous pseudogene sequence to its 5′ regulatory region on chromosome 3: Implications for polymorphic studies in diabetes
    • 10.2337/diabetes.50.12.2646 11723045
    • BI Stickland MH Grant PJ Futers TS Characterization of allelic and nucleotide variation between the RAGE gene on chromosome 6 and a homologous pseudogene sequence to its 5′ regulatory region on chromosome 3: Implications for polymorphic studies in diabetes Diabetes 2001, 50:2646-2651. 10.2337/diabetes.50.12.2646 11723045
    • (2001) Diabetes , vol.50 , pp. 2646-2651
    • Hudson, B.I.1    Stickland, M.H.2    Grant, P.J.3    Futers, T.S.4
  • 80
    • 0034760412 scopus 로고    scopus 로고
    • Polymorphisms 1704G/T and 2184A/G in the RAGE gene are associated with antioxidant status
    • 10.1053/meta.2001.26757 11586486
    • Kankova K Marova I Zahejsky J Muzik J Stejskalova A Znojil V Vacha J Polymorphisms 1704G/T and 2184A/G in the RAGE gene are associated with antioxidant status Metabolism 2001, 50:1152-1160. 10.1053/ meta.2001.26757 11586486
    • (2001) Metabolism , vol.50 , pp. 1152-1160
    • Kankova, K.1    Marova, I.2    Zahejsky, J.3    Muzik, J.4    Stejskalova, A.5    Znojil, V.6    Vacha, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.