메뉴 건너뛰기




Volumn 49, Issue 4, 2008, Pages 1696-1704

FGF19 exhibits neuroprotective effects on adult mammalian photoreceptors in vitro

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 19; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 4; LEUCINE ZIPPER PROTEIN; PHOSPHOTYROSINE; UNCLASSIFIED DRUG; FGF19 PROTEIN, HUMAN; FGFR4 PROTEIN, HUMAN; MESSENGER RNA; NEUROPROTECTIVE AGENT; RECOMBINANT PROTEIN;

EID: 45549093697     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1272     Document Type: Article
Times cited : (18)

References (60)
  • 1
    • 33846964895 scopus 로고    scopus 로고
    • Contributions of genetics to our understanding of inherited monogenic retinal diseases and age-related macular degeneration
    • Bok D. Contributions of genetics to our understanding of inherited monogenic retinal diseases and age-related macular degeneration. Arch Ophthalmol. 2007;125:160-164.
    • (2007) Arch Ophthalmol , vol.125 , pp. 160-164
    • Bok, D.1
  • 2
    • 33646092544 scopus 로고    scopus 로고
    • Progressive cone and cone-rod dystrophies: Phenotypes and underlying molecular genetic basis
    • Michaelides M, Hardcastle AJ, Hunt DM, Moore AT. Progressive cone and cone-rod dystrophies: phenotypes and underlying molecular genetic basis. Surv Ophthalmol. 2006;51:232-258.
    • (2006) Surv Ophthalmol , vol.51 , pp. 232-258
    • Michaelides, M.1    Hardcastle, A.J.2    Hunt, D.M.3    Moore, A.T.4
  • 3
    • 11144273817 scopus 로고    scopus 로고
    • Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotec- tion for retinal degeneration
    • Wenzel A, Grimm C, Samardzija M, Reme CE. Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotec- tion for retinal degeneration. Prog Retin Eye Res. 2005;24:275- 306.
    • (2005) Prog Retin Eye Res , vol.24 , pp. 275-306
    • Wenzel, A.1    Grimm, C.2    Samardzija, M.3    Reme, C.E.4
  • 4
    • 34247195487 scopus 로고    scopus 로고
    • Age-related macular degeneration: The costs to society and the patient
    • Gupta OP, Brown GC, Brown MM. Age-related macular degeneration: the costs to society and the patient. Curr Opin Ophthalmol. 2007;18: 201-205.
    • (2007) Curr Opin Ophthalmol , vol.18 , pp. 201-205
    • Gupta, O.P.1    Brown, G.C.2    Brown, M.M.3
  • 5
    • 33747410191 scopus 로고    scopus 로고
    • Molecular mechanisms of neuro- protection in the eye
    • Barnstable CJ, Tombran-Tink J. Molecular mechanisms of neuro- protection in the eye. Adv Exp Med Biol. 2006;572:291-295.
    • (2006) Adv Exp Med Biol , vol.572 , pp. 291-295
    • Barnstable, C.J.1    Tombran-Tink, J.2
  • 6
    • 0037214277 scopus 로고    scopus 로고
    • Retinal neuroprotection by growth factors: A mechanistic perspective
    • Chaum E. Retinal neuroprotection by growth factors: a mechanistic perspective. J Cell Biochem. 2003;88:57-75.
    • (2003) J Cell Biochem , vol.88 , pp. 57-75
    • Chaum, E.1
  • 7
    • 0032925488 scopus 로고    scopus 로고
    • Repeated injections of a ciliary neurotrophic factor analogue leading to long-term photoreceptor survival in hereditary retinal degeneration
    • Chong NH, Alexander RA, Waters L, Barnett KC, Bird AC, Luthert PJ. Repeated injections of a ciliary neurotrophic factor analogue leading to long-term photoreceptor survival in hereditary retinal degeneration. Invest Ophthalmol Vis Sci. 1999;40:1298-1305.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 1298-1305
    • Chong, N.H.1    Alexander, R.A.2    Waters, L.3    Barnett, K.C.4    Bird, A.C.5    Luthert, P.J.6
  • 8
    • 0034980737 scopus 로고    scopus 로고
    • AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse
    • Liang FQ, Dejneka NS, Cohen DR, et al. AAV-mediated delivery of ciliary neurotrophic factor prolongs photoreceptor survival in the rhodopsin knockout mouse. Mol Ther. 2001;3:241-248.
    • (2001) Mol Ther , vol.3 , pp. 241-248
    • Liang, F.Q.1    Dejneka, N.S.2    Cohen, D.R.3
  • 9
    • 0032829894 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse
    • Frasson M, Picaud S, Leveillard T, et al. Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse. Invest Ophthalmol Vis Sci. 1999;40:2724-2734.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 2724-2734
    • Frasson, M.1    Picaud, S.2    Leveillard, T.3
  • 10
    • 0035664438 scopus 로고    scopus 로고
    • Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa
    • McGee Sanftner LH, Abel H, Hauswirth WW, FlanneryJG. Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa. Mol Ther. 2001;4:622-629.
    • (2001) Mol Ther , vol.4 , pp. 622-629
    • McGee Sanftner, L.H.1    Abel, H.2    Hauswirth, W.W.3    FlanneryJG4
  • 11
    • 0025062946 scopus 로고
    • Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor
    • Faktorovich EG, Steinberg RH, Yasumura D, Matthes MT, LaVail MM. Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor. Nature. 1990;347:83-86.
    • (1990) Nature , vol.347 , pp. 83-86
    • Faktorovich, E.G.1    Steinberg, R.H.2    Yasumura, D.3    Matthes, M.T.4    LaVail, M.M.5
  • 12
    • 0026666404 scopus 로고
    • Basic fibroblast growth factor and local injury protect photo- receptors from light damage in the rat
    • Faktorovich EG, Steinberg RH, Yasumura D, Matthes MT, LaVail MM. Basic fibroblast growth factor and local injury protect photo- receptors from light damage in the rat. J Neurosci. 1992;12:3554 - 3567.
    • (1992) J Neurosci , vol.12 , pp. 3554-3567
    • Faktorovich, E.G.1    Steinberg, R.H.2    Yasumura, D.3    Matthes, M.T.4    LaVail, M.M.5
  • 13
    • 0031937530 scopus 로고    scopus 로고
    • Protection of mouse photoreceptors by survival factors in retinal degenerations
    • LaVail MM, Yasumura D, Matthes MT, et al. Protection of mouse photoreceptors by survival factors in retinal degenerations. Invest Ophthalmol Vis Sci. 1998;39:592- 602.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 592-602
    • LaVail, M.M.1    Yasumura, D.2    Matthes, M.T.3
  • 14
    • 0033774933 scopus 로고    scopus 로고
    • Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2
    • Lau D, McGee LH, Zhou S, et al. Retinal degeneration is slowed in transgenic rats by AAV-mediated delivery of FGF-2. Invest Ophthalmol Vis Sci. 2000;41:3622-3633.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3622-3633
    • Lau, D.1    McGee, L.H.2    Zhou, S.3
  • 15
    • 0026647370 scopus 로고
    • Fibroblast growth factor stimulates photore- ceptor differentiation in vitro
    • Hicks D, Courtois Y. Fibroblast growth factor stimulates photore- ceptor differentiation in vitro. J Neurosci. 1992;12:2022-2033.
    • (1992) J Neurosci , vol.12 , pp. 2022-2033
    • Hicks, D.1    Courtois, Y.2
  • 16
    • 0032403408 scopus 로고    scopus 로고
    • Survival of purified rat photoreceptors in vitro is stimulated directly by fibroblast growth factor-2
    • Fontaine V, Kinkl N, Sahel J, Dreyfus H, Hicks D. Survival of purified rat photoreceptors in vitro is stimulated directly by fibroblast growth factor-2. J Neurosci. 1998;18:9662-9672.
    • (1998) J Neurosci , vol.18 , pp. 9662-9672
    • Fontaine, V.1    Kinkl, N.2    Sahel, J.3    Dreyfus, H.4    Hicks, D.5
  • 17
    • 0141764823 scopus 로고    scopus 로고
    • Basic fibroblast and epidermal growth factors stimulate survival in adult porcine pho- toreceptor cell cultures
    • Traverso V, Kinkl N, Grimm L, Sahel J, Hicks D. Basic fibroblast and epidermal growth factors stimulate survival in adult porcine pho- toreceptor cell cultures. Invest Ophthalmol Vis Sci. 2003;44: 4550-4558.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 4550-4558
    • Traverso, V.1    Kinkl, N.2    Grimm, L.3    Sahel, J.4    Hicks, D.5
  • 18
    • 0035941217 scopus 로고    scopus 로고
    • Alternate FGF2-ERK1/2 signaling pathways in retinal photoreceptor and glial cells in vitro
    • Kinkl N, Sahel J, Hicks D. Alternate FGF2-ERK1/2 signaling pathways in retinal photoreceptor and glial cells in vitro. J Biol Chem. 2001;276:43871-43878.
    • (2001) J Biol Chem , vol.276 , pp. 43871-43878
    • Kinkl, N.1    Sahel, J.2    Hicks, D.3
  • 19
    • 0034980919 scopus 로고    scopus 로고
    • Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18
    • Green ES, Rendahl KG, Zhou S, et al. Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18. Mol Ther. 2001;3:507- 515.
    • (2001) Mol Ther , vol.3 , pp. 507-515
    • Green, E.S.1    Rendahl, K.G.2    Zhou, S.3
  • 20
    • 0036978854 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor (FGFR) and candidate signaling molecule distribution within rat and human retina
    • Kinkl N, Hageman GS, Sahel JA, Hicks D. Fibroblast growth factor receptor (FGFR) and candidate signaling molecule distribution within rat and human retina. Mol Vis. 2002;8:149-160.
    • (2002) Mol Vis , vol.8 , pp. 149-160
    • Kinkl, N.1    Hageman, G.S.2    Sahel, J.A.3    Hicks, D.4
  • 21
    • 0038512174 scopus 로고    scopus 로고
    • Possible involvement of a fibroblast growth factor 9 (FGF9)-FGF receptor- 3-mediated pathway in adult pig retinal ganglion cell survival in vitro
    • Kinkl N, Ruiz J, Vecino E, Frasson M, Sahel J, Hicks D. Possible involvement of a fibroblast growth factor 9 (FGF9)-FGF receptor- 3-mediated pathway in adult pig retinal ganglion cell survival in vitro. Mol Cell Neurosci. 2003;23:39 -53.
    • (2003) Mol Cell Neurosci , vol.23 , pp. 39-53
    • Kinkl, N.1    Ruiz, J.2    Vecino, E.3    Frasson, M.4    Sahel, J.5    Hicks, D.6
  • 22
    • 0033376775 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 4 (FGFR4) is expressed in adult rat and human retinal photoreceptors and neurons
    • Fuhrmann V, Kinkl N, Leveillard T, Sahel J, Hicks D. Fibroblast growth factor receptor 4 (FGFR4) is expressed in adult rat and human retinal photoreceptors and neurons. J Mol Neurosci. 1999; 13:187-197.
    • (1999) J Mol Neurosci , vol.13 , pp. 187-197
    • Fuhrmann, V.1    Kinkl, N.2    Leveillard, T.3    Sahel, J.4    Hicks, D.5
  • 23
    • 14944379126 scopus 로고    scopus 로고
    • Acidic fibroblast growth factor (FGF-1) and FGF receptor 1 signaling in human Y79 retinoblastoma
    • Siffroi-Fernandez S, Cinaroglu A, Fuhrmann-Panfalone V, et al. Acidic fibroblast growth factor (FGF-1) and FGF receptor 1 signaling in human Y79 retinoblastoma. Arch Ophthalmol. 2005;123: 368-376.
    • (2005) Arch Ophthalmol , vol.123 , pp. 368-376
    • Siffroi-Fernandez, S.1    Cinaroglu, A.2    Fuhrmann-Panfalone, V.3
  • 24
    • 0028808094 scopus 로고
    • Identification of fibroblast growth factor 9 (FGF9) as a high affinity, heparin dependent ligand for FGF receptors 3 and 2 but not for FGF receptors 1 and 4
    • Hecht D, Zimmerman N, Bedford M, Avivi A, Yayon A. Identification of fibroblast growth factor 9 (FGF9) as a high affinity, heparin dependent ligand for FGF receptors 3 and 2 but not for FGF receptors 1 and 4. Growth Factors. 1995;12:223-233.
    • (1995) Growth Factors , vol.12 , pp. 223-233
    • Hecht, D.1    Zimmerman, N.2    Bedford, M.3    Avivi, A.4    Yayon, A.5
  • 25
    • 1842816370 scopus 로고    scopus 로고
    • Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction
    • Wright TJ, Ladher R, McWhirter J, Murre C, Schoenwolf GC, Mansour SL. Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction. Dev Biol. 2004;269:264-275.
    • (2004) Dev Biol , vol.269 , pp. 264-275
    • Wright, T.J.1    Ladher, R.2    McWhirter, J.3    Murre, C.4    Schoenwolf, G.C.5    Mansour, S.L.6
  • 26
    • 0032822672 scopus 로고    scopus 로고
    • FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4
    • Xie MH, Holcomb I, Deuel B, et al. FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4. Cytokine. 1999; 11:729-735.
    • (1999) Cytokine , vol.11 , pp. 729-735
    • Xie, M.H.1    Holcomb, I.2    Deuel, B.3
  • 28
    • 4744339897 scopus 로고    scopus 로고
    • Expression of fibroblast growth factor 19 (Fgf19) during chicken embry- ogenesis and eye development, compared with Fgf15 expression in the mouse
    • Kurose H, Bito T, Adachi T, Shimizu M, Noji S, Ohuchi H. Expression of fibroblast growth factor 19 (Fgf19) during chicken embry- ogenesis and eye development, compared with Fgf15 expression in the mouse. Gene Expr Patterns. 2004;4:687-693.
    • (2004) Gene Expr Patterns , vol.4 , pp. 687-693
    • Kurose, H.1    Bito, T.2    Adachi, T.3    Shimizu, M.4    Noji, S.5    Ohuchi, H.6
  • 29
    • 21344452372 scopus 로고    scopus 로고
    • FGF19-FGFR4 signaling elaborates lens induction with the FGF8-L-Maf cascade in the chickembryo
    • Kurose H, Okamoto M, Shimizu M, et al. FGF19-FGFR4 signaling elaborates lens induction with the FGF8-L-Maf cascade in the chickembryo. Dev Growth Differ. 2005;47 213-223.
    • (2005) Dev Growth Differ , vol.47 , pp. 213-223
    • Kurose, H.1    Okamoto, M.2    Shimizu, M.3
  • 30
    • 0022571973 scopus 로고
    • Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin
    • Hicks D, Molday RS. Differential immunogold-dextran labeling of bovine and frog rod and cone cells using monoclonal antibodies against bovine rhodopsin. Exp Eye Res. 1986;42:55-71.
    • (1986) Exp Eye Res , vol.42 , pp. 55-71
    • Hicks, D.1    Molday, R.S.2
  • 31
    • 0035965196 scopus 로고    scopus 로고
    • Multiple phosphorylated isoforms ofNRL are expressed in rod photoreceptors
    • Swain PK, Hicks D, Mears AJ, et al. Multiple phosphorylated isoforms ofNRL are expressed in rod photoreceptors. J Biol Chem. 2001;276:36824-36830.
    • (2001) J Biol Chem , vol.276 , pp. 36824-36830
    • Swain, P.K.1    Hicks, D.2    Mears, A.J.3
  • 32
    • 0030041756 scopus 로고    scopus 로고
    • erbB family receptor expression and growth regulation in a newly isolated human breast cancer cell line
    • Ethier SP, Kokeny KE, Ridings JW, Dilts CA. erbB family receptor expression and growth regulation in a newly isolated human breast cancer cell line. Cancer Res. 1996;56:899 -907.
    • (1996) Cancer Res , vol.56 , pp. 899-907
    • Ethier, S.P.1    Kokeny, K.E.2    Ridings, J.W.3    Dilts, C.A.4
  • 33
    • 64549138637 scopus 로고    scopus 로고
    • Forster V, Dreyfus H, Hicks D. Adult mammalian retina. In: Haynes LW, ed. The Neuron in Tissue Culture. Methods in Neuroscience, IBRO Handbook Series. New York: Wiley & Sons; 579-585.
    • Forster V, Dreyfus H, Hicks D. Adult mammalian retina. In: Haynes LW, ed. The Neuron in Tissue Culture. Methods in Neuroscience, IBRO Handbook Series. New York: Wiley & Sons; 579-585.
  • 34
    • 0028277828 scopus 로고
    • Superoxide inhibits proliferation and phagocytic internalization of photoreceptor outer segments by bovine retinal pigment epithelium in vitro
    • Becquet F, Goureau O, Soubrane G, Coscas G, Courtois Y, Hicks D. Superoxide inhibits proliferation and phagocytic internalization of photoreceptor outer segments by bovine retinal pigment epithelium in vitro. Exp Cell Res. 1994;212:374-82.
    • (1994) Exp Cell Res , vol.212 , pp. 374-382
    • Becquet, F.1    Goureau, O.2    Soubrane, G.3    Coscas, G.4    Courtois, Y.5    Hicks, D.6
  • 35
    • 0038147058 scopus 로고    scopus 로고
    • Stability of RNA from the retina and retinal pigment epithelium in a porcine model simulating human eye bank conditions
    • Malik KJ, Chen CD, Olsen TW. Stability of RNA from the retina and retinal pigment epithelium in a porcine model simulating human eye bank conditions. Invest Ophthalmol Vis Sci. 2003;44 2730 - 2735.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 2730-2735
    • Malik, K.J.1    Chen, C.D.2    Olsen, T.W.3
  • 37
    • 0021990499 scopus 로고
    • Toxicity determined in vitro by morphological alterations and neutral red absorption
    • Borenfreund E, Puerner JA. Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicol Lett. 1985;24:119-124.
    • (1985) Toxicol Lett , vol.24 , pp. 119-124
    • Borenfreund, E.1    Puerner, J.A.2
  • 38
    • 1642494893 scopus 로고    scopus 로고
    • The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity
    • Harmer NJ, Pellegrini L, Chirgadze D, Fernandez-Recio J, Blun- dell TL. The crystal structure of fibroblast growth factor (FGF) 19 reveals novel features of the FGF family and offers a structural basis for its unusual receptor affinity. Biochemistry. 2004; 43:629-640.
    • (2004) Biochemistry , vol.43 , pp. 629-640
    • Harmer, N.J.1    Pellegrini, L.2    Chirgadze, D.3    Fernandez-Recio, J.4    Blun- dell, T.L.5
  • 39
    • 0033579972 scopus 로고    scopus 로고
    • Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain
    • Nishimura T, Utsunomiya Y, Hoshikawa M, Ohuchi H, Itoh N. Structure and expression of a novel human FGF, FGF-19, expressed in the fetal brain. Biochim Biophys Acta. 1999;1444:148- 151.
    • (1999) Biochim Biophys Acta , vol.1444 , pp. 148-151
    • Nishimura, T.1    Utsunomiya, Y.2    Hoshikawa, M.3    Ohuchi, H.4    Itoh, N.5
  • 40
    • 0028178869 scopus 로고
    • Rat FGF receptor-4 mRNA in the brain is expressed preferentially in the medial habenular nucleus
    • 40
    • 40.Itoh N, Yazaki N, Tagashira S, et al. Rat FGF receptor-4 mRNA in the brain is expressed preferentially in the medial habenular nucleus. Brain Res Mol Brain Res. 1994;21:344-348.
    • (1994) Brain Res Mol Brain Res , vol.21 , pp. 344-348
    • Itoh, N.1    Yazaki, N.2    Tagashira, S.3
  • 41
    • 1342328598 scopus 로고    scopus 로고
    • Differential distribution of fibroblast growth factor receptors (FGFRs) on fo- veal cones: FGFR-4 is an early marker of cone photoreceptors
    • Cornish EE, Natoli RC, Hendrickson A, Provis JM. Differential distribution of fibroblast growth factor receptors (FGFRs) on fo- veal cones: FGFR-4 is an early marker of cone photoreceptors. Mol Vis. 2004;10:1-14.
    • (2004) Mol Vis , vol.10 , pp. 1-14
    • Cornish, E.E.1    Natoli, R.C.2    Hendrickson, A.3    Provis, J.M.4
  • 42
    • 32544457871 scopus 로고    scopus 로고
    • Gradients of cone differentiation and FGF expression during development of the foveal depression in macaque retina
    • Cornish EE, Madigan MC, Natoli R, Hales A, Hendrickson AE, Provis JM. Gradients of cone differentiation and FGF expression during development of the foveal depression in macaque retina. Vis Neurosci. 2005;22:447-459.
    • (2005) Vis Neurosci , vol.22 , pp. 447-459
    • Cornish, E.E.1    Madigan, M.C.2    Natoli, R.3    Hales, A.4    Hendrickson, A.E.5    Provis, J.M.6
  • 43
    • 0042327991 scopus 로고    scopus 로고
    • Targeted expression of the dominant-negative FGFR4a in the eye using Xrx1A regulatory sequences interferes with normal retinal development
    • Zhang L, El-Hodiri HM, Ma HF, et al. Targeted expression of the dominant-negative FGFR4a in the eye using Xrx1A regulatory sequences interferes with normal retinal development. Development. 2003;130:4177- 4186.
    • (2003) Development , vol.130 , pp. 4177-4186
    • Zhang, L.1    El-Hodiri, H.M.2    Ma, H.F.3
  • 44
    • 0028927879 scopus 로고
    • bFGF and aFGF induce membrane ruffling in breast cancer cells but not in normal breast epithelial cells: FGFR-4 involvement
    • Johnston CL, Cox HC, Gomm JJ, Coombes RC. bFGF and aFGF induce membrane ruffling in breast cancer cells but not in normal breast epithelial cells: FGFR-4 involvement. Biochem J. 1995;306: 609 - 616.
    • (1995) Biochem J , vol.306 , pp. 609-616
    • Johnston, C.L.1    Cox, H.C.2    Gomm, J.J.3    Coombes, R.C.4
  • 45
    • 0025778586 scopus 로고
    • FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern
    • Partanen J, Makela TP, Eerola E, et al. FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J. 1991;10 1347-1354.
    • (1991) EMBO J , vol.10 , pp. 1347-1354
    • Partanen, J.1    Makela, T.P.2    Eerola, E.3
  • 46
    • 0028332812 scopus 로고
    • Signal transduction by fibroblast growth factor receptor-4 (FGFR-4): Comparison with FGFR-1
    • Vainikka S, Joukov V, Wennstrom S, Bergman M, Pelicci PG, Alitalo K. Signal transduction by fibroblast growth factor receptor-4 (FGFR-4): comparison with FGFR-1. J Biol Chem. 1994;269: 18320-18326.
    • (1994) J Biol Chem , vol.269 , pp. 18320-18326
    • Vainikka, S.1    Joukov, V.2    Wennstrom, S.3    Bergman, M.4    Pelicci, P.G.5    Alitalo, K.6
  • 47
    • 0027955135 scopus 로고
    • Fibroblast growth factor receptors have different signaling and mitogenic potentials
    • Wang JK, Gao G, Goldfarb M. Fibroblast growth factor receptors have different signaling and mitogenic potentials. Mol Cell Biol. 1994;14:181-188.
    • (1994) Mol Cell Biol , vol.14 , pp. 181-188
    • Wang, J.K.1    Gao, G.2    Goldfarb, M.3
  • 48
    • 0030033411 scopus 로고    scopus 로고
    • Association of a 85-kDa serine kinase with activated fibroblast growth factor receptor-4
    • Vainikka S, Joukov V, Klint P, Alitalo K. Association of a 85-kDa serine kinase with activated fibroblast growth factor receptor-4. J Biol Chem. 1996;271:1270-1273.
    • (1996) J Biol Chem , vol.271 , pp. 1270-1273
    • Vainikka, S.1    Joukov, V.2    Klint, P.3    Alitalo, K.4
  • 49
    • 35748973876 scopus 로고    scopus 로고
    • Co-receptor requirements for fibroblast growth factor-19 signaling
    • Wu X, Ge H, Gupte J, et al. Co-receptor requirements for fibroblast growth factor-19 signaling. J Biol Chem. 2007;282: 29069-29072.
    • (2007) J Biol Chem , vol.282 , pp. 29069-29072
    • Wu, X.1    Ge, H.2    Gupte, J.3
  • 50
    • 34848869695 scopus 로고    scopus 로고
    • Tissue-specific expression of βklotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
    • Kurosu H, Choi M, Ogawa Y, et al. Tissue-specific expression of βklotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J Biol Chem. 2007;282:26687-26695.
    • (2007) J Biol Chem , vol.282 , pp. 26687-26695
    • Kurosu, H.1    Choi, M.2    Ogawa, Y.3
  • 51
    • 18344394556 scopus 로고    scopus 로고
    • Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity
    • Tomlinson E, Fu L, John L, et al. Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity. Endocrinology. 2002;143:1741- 1747.
    • (2002) Endocrinology , vol.143 , pp. 1741-1747
    • Tomlinson, E.1    Fu, L.2    John, L.3
  • 52
    • 0034685916 scopus 로고    scopus 로고
    • Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4
    • Yu C, Wang F, Kan M, et al. Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4. J Biol Chem. 2000;275:15482-15489.
    • (2000) J Biol Chem , vol.275 , pp. 15482-15489
    • Yu, C.1    Wang, F.2    Kan, M.3
  • 54
    • 0035734382 scopus 로고    scopus 로고
    • Nrl is required for rod photoreceptor development
    • Mears AJ, Kondo M, Swain PK, et al. Nrl is required for rod photoreceptor development. Nat Genet. 2001;29:447-452.
    • (2001) Nat Genet , vol.29 , pp. 447-452
    • Mears, A.J.1    Kondo, M.2    Swain, P.K.3
  • 55
    • 34447555859 scopus 로고    scopus 로고
    • Mutations associated with retinopathies alter mitogen-activated protein kinase-induced phosphorylation of neural retina leucine-zipper
    • Swain P, Kumar S, Patel D, et al. Mutations associated with retinopathies alter mitogen-activated protein kinase-induced phosphorylation of neural retina leucine-zipper. Mol Vis. 2007; 13:1114-1120.
    • (2007) Mol Vis , vol.13 , pp. 1114-1120
    • Swain, P.1    Kumar, S.2    Patel, D.3
  • 56
    • 15844368097 scopus 로고    scopus 로고
    • Receptor specificity of the fibroblast growth factor family
    • Ornitz DM, Xu J, Colvin JS, et al. Receptor specificity of the fibroblast growth factor family. J Biol Chem. 1996;271:15292-15297.
    • (1996) J Biol Chem , vol.271 , pp. 15292-15297
    • Ornitz, D.M.1    Xu, J.2    Colvin, J.S.3
  • 57
  • 58
    • 0026056194 scopus 로고
    • Neovascular growth factors
    • Schultz GS, Grant MB. Neovascular growth factors. Eye. 1991;5: 170 -180.
    • (1991) Eye , vol.5 , pp. 170-180
    • Schultz, G.S.1    Grant, M.B.2
  • 59
    • 0031659904 scopus 로고    scopus 로고
    • Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization
    • Ozaki H, Okamoto N, Ortega S, et al. Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization. Am J Pathol. 1998;153:757-765.
    • (1998) Am J Pathol , vol.153 , pp. 757-765
    • Ozaki, H.1    Okamoto, N.2    Ortega, S.3
  • 60
    • 0033845246 scopus 로고    scopus 로고
    • Up-regulation and co-expression of fibroblast growth factor receptors in human gastric cancer
    • Shin EY, Lee BH, Yang JH, et al. Up-regulation and co-expression of fibroblast growth factor receptors in human gastric cancer. J Cancer Res Clin Oncol. 2000;126:519-528.
    • (2000) J Cancer Res Clin Oncol , vol.126 , pp. 519-528
    • Shin, E.Y.1    Lee, B.H.2    Yang, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.