C2-ceramide mediates cerebellar granule cells apoptosis by activation of caspases-2, -9, and -3

Journal of Neuroscience Research

Volumn 86, Issue 8, 2008, Pages 1734-1747

  Miñano, Alfredo ^a,b   Caballero Benítez, Andrea ^a,c   Lluch, Mónica ^a   Morán, Julio ^c   Rodríguez Alvarez, José ^a,b,d  

^a INSTITUT DE NEUROCIÈNCIES   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Cerebellum; Neuronal death; Neurons; Rat

Indexed keywords

C2 CERAMIDE; CASPASE 2; CASPASE 3; CASPASE 9; CERAMIDE DERIVATIVE; CYTOCHROME; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; DRUG DERIVATIVE; ENZYME INHIBITOR; N ACETYLSPHINGOSINE; N-ACETYLSPHINGOSINE; SPHINGOSINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; GRANULE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; CELL SURVIVAL; CEREBELLUM; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CASPASE 2; CASPASE 3; CASPASE 9; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; RATS; SPHINGOSINE;

EID: 45549088433     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21633     Document Type: Article

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