메뉴 건너뛰기




Volumn 5, Issue 6, 2004, Pages 627-641

Pharmacogenomics and stomach cancer

Author keywords

5 fluorouracil; Anthracyclines; Gastric; Irinotecan; Methotrexate; Mitomycin C; Pharmacogenetics; Platinum; Polymorphism; Taxanes

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; ANTHRACYCLINE DERIVATIVE; CAPECITABINE; CISPLATIN; DAUNORUBICIN; DIGOXIN; DIHYDROFLUOROURACIL; DIHYDROFOLIC ACID; DNA TOPOISOMERASE INHIBITOR; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLOXURIDINE PHOSPHATE; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; METHOTREXATE; METHYLENETETRAHYDROFOLIC ACID; MITOMYCIN C; OXALIPLATIN; PACLITAXEL; PHENYTOIN; PROTEINASE INHIBITOR; TAXANE DERIVATIVE; TEGAFUR; TETRAHYDROFOLIC ACID; THYMIDINE PHOSPHATE; UNINDEXED DRUG;

EID: 4544388467     PISSN: 14622416     EISSN: None     Source Type: Journal    
DOI: 10.1517/14622416.5.6.627     Document Type: Review
Times cited : (6)

References (103)
  • 1
    • 0033816806 scopus 로고    scopus 로고
    • Efficacy of adjuvant chemotherapy after curative resection for gastric cancer: A meta-analysis of published randomised trials. A study of the GISCAD (Gruppo Italiano per lo Studio dei Carcinomi dell'Apparato Digerente)
    • Mari E, Floriani I, Tinazzi A et al.: Efficacy of adjuvant chemotherapy after curative resection for gastric cancer: a meta-analysis of published randomised trials. A study of the GISCAD (Gruppo Italiano per lo Studio dei Carcinomi dell'Apparato Digerente). Ann. Oncol. 11(7), 837-843 (2000).
    • (2000) Ann. Oncol. , vol.11 , Issue.7 , pp. 837-843
    • Mari, E.1    Floriani, I.2    Tinazzi, A.3
  • 2
    • 0036434492 scopus 로고    scopus 로고
    • New drugs for treatment of gastric cancer
    • Schoffski P: New drugs for treatment of gastric cancer. Ann. Oncol. 13(Suppl. 4),13-22 (2002).
    • (2002) Ann. Oncol. , vol.13 , Issue.SUPPL. 4 , pp. 13-22
    • Schoffski, P.1
  • 3
    • 0035818048 scopus 로고    scopus 로고
    • Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction
    • Macdonald JS, Smalley SR, Benedetti J et al.: Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N. Engl. J. Med. 345(10), 725-730 (2001).
    • (2001) N. Engl. J. Med. , vol.345 , Issue.10 , pp. 725-730
    • Macdonald, J.S.1    Smalley, S.R.2    Benedetti, J.3
  • 4
    • 0037421590 scopus 로고    scopus 로고
    • Pharmacogenomics - Drug disposition, drug targets, and side effects
    • Evans WE, McLeod HL: Pharmacogenomics - drug disposition, drug targets, and side effects. N. Engl. J. Med. 348(6), 538-549 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , Issue.6 , pp. 538-549
    • Evans, W.E.1    McLeod, H.L.2
  • 5
    • 0017716458 scopus 로고
    • Thymidylate synthetase - A target enzyme in cancer chemotherapy
    • Danenberg PV: Thymidylate synthetase - a target enzyme in cancer chemotherapy. Biochim. Biophys. Acta 473(2), 73-92 (1977).
    • (1977) Biochim. Biophys. Acta , vol.473 , Issue.2 , pp. 73-92
    • Danenberg, P.V.1
  • 6
    • 33745464490 scopus 로고
    • Fluorinated pyrimidines, a new class of tumor-inhibitory compounds
    • Heidelberger C, Chaudhuri NK, Danneberg P et al.: Fluorinated pyrimidines, a new class of tumor-inhibitory compounds. Nature 179(4561), 663-666 (1957).
    • (1957) Nature , vol.179 , Issue.4561 , pp. 663-666
    • Heidelberger, C.1    Chaudhuri, N.K.2    Danneberg, P.3
  • 7
    • 0031982522 scopus 로고    scopus 로고
    • ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy
    • Metzger R, Leichman CG, Danenberg KD et al.: ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J. Clin. Oncol. 16(1), 309-316 (1998).
    • (1998) J. Clin. Oncol. , vol.16 , Issue.1 , pp. 309-316
    • Metzger, R.1    Leichman, C.G.2    Danenberg, K.D.3
  • 8
    • 0032080712 scopus 로고    scopus 로고
    • High expression of thymidylate synthase is associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy
    • Yeh KH, Shun CT, Chen CL et al.: High expression of thymidylate synthase is associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy. Cancer 82(9), 1626-1631 (1998).
    • (1998) Cancer , vol.82 , Issue.9 , pp. 1626-1631
    • Yeh, K.H.1    Shun, C.T.2    Chen, C.L.3
  • 9
    • 0029122937 scopus 로고
    • Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
    • Horie N, Aiba H, Oguro K, Hojo H, Takeishi K: Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct. Funct. 20(3), 191-197 (1995).
    • (1995) Cell Struct. Funct. , vol.20 , Issue.3 , pp. 191-197
    • Horie, N.1    Aiba, H.2    Oguro, K.3    Hojo, H.4    Takeishi, K.5
  • 10
    • 0035750549 scopus 로고    scopus 로고
    • Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
    • Pullarkat ST, Stoehlmacher J, Ghaderi V et al.: Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J. 1(1), 65-70 (2001).
    • (2001) Pharmacogenomics J. , vol.1 , Issue.1 , pp. 65-70
    • Pullarkat, S.T.1    Stoehlmacher, J.2    Ghaderi, V.3
  • 11
    • 0035860142 scopus 로고    scopus 로고
    • A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil
    • Iacopetta B, Grieu F, Joseph D, Elsaleh H: A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil. Br. J. Cancer 85(6), 827-830 (2001).
    • (2001) Br. J. Cancer , vol.85 , Issue.6 , pp. 827-830
    • Iacopetta, B.1    Grieu, F.2    Joseph, D.3    Elsaleh, H.4
  • 12
    • 0035868667 scopus 로고    scopus 로고
    • Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer
    • Villafranca E, Okruzhnov Y, Dominguez MA et al.: Polymorphisms of the repeated sequences in the enhancer region of the thymidylate synthase gene promoter may predict downstaging after preoperative chemoradiation in rectal cancer. J. Clin. Oncol. 19(6), 1779-1786 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , Issue.6 , pp. 1779-1786
    • Villafranca, E.1    Okruzhnov, Y.2    Dominguez, M.A.3
  • 14
    • 0036765664 scopus 로고    scopus 로고
    • Association of thymidylate synthase gene polymorphism with its mRNA and protein expression and with prognosis in gastric cancer
    • Ishida Y, Kawakami K, Tanaka Y, Kanehira E, Omura K, Watanabe G: Association of thymidylate synthase gene polymorphism with its mRNA and protein expression and with prognosis in gastric cancer. Anticancer Res. 22(5), 2805-2809 (2002).
    • (2002) Anticancer Res. , vol.22 , Issue.5 , pp. 2805-2809
    • Ishida, Y.1    Kawakami, K.2    Tanaka, Y.3    Kanehira, E.4    Omura, K.5    Watanabe, G.6
  • 15
    • 0036355046 scopus 로고    scopus 로고
    • Thymidylate synthase gene polymorphism predicts response to capecitabine in advanced colorectal cancer
    • Park DJ, Stoehlmacher J, Zhang W, Tsao-Wei D, Groshen S, Lenz HJ: Thymidylate synthase gene polymorphism predicts response to capecitabine in advanced colorectal cancer. Int. J. Colorectal Dis. 17(1), 46-49 (2002).
    • (2002) Int. J. Colorectal Dis. , vol.17 , Issue.1 , pp. 46-49
    • Park, D.J.1    Stoehlmacher, J.2    Zhang, W.3    Tsao-Wei, D.4    Groshen, S.5    Lenz, H.J.6
  • 16
    • 12444302837 scopus 로고    scopus 로고
    • Polymorphism in the thymidylate synthase promoter enhancer region is not an efficacious marker for tumor sensitivity to 5-fluorouracil-based oral adjuvant chemotherapy in colorectal cancer
    • Tsuji T, Hidaka S, Sawai T et al.: Polymorphism in the thymidylate synthase promoter enhancer region is not an efficacious marker for tumor sensitivity to 5-fluorouracil-based oral adjuvant chemotherapy in colorectal cancer. Clin. Cancer Res. 10(Part 1), 3700-3704 (2003).
    • (2003) Clin. Cancer Res. , vol.10 , Issue.PART 1 , pp. 3700-3704
    • Tsuji, T.1    Hidaka, S.2    Sawai, T.3
  • 17
    • 0037567591 scopus 로고    scopus 로고
    • A novel single nucleotide polymorphism within the 5′ tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity
    • Mandola MV, Stoehlmacher J, Muller-Weeks S et al.: A novel single nucleotide polymorphism within the 5′ tandem repeat polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity. Cancer Res. 63(11), 2898-2904 (2003 ).
    • (2003) Cancer Res. , vol.63 , Issue.11 , pp. 2898-2904
    • Mandola, M.V.1    Stoehlmacher, J.2    Muller-Weeks, S.3
  • 18
    • 0141507954 scopus 로고    scopus 로고
    • Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene
    • Kawakami K, Watanabe G: Identification and functional analysis of single nucleotide polymorphism in the tandem repeat sequence of thymidylate synthase gene. Cancer Res. 63(18), 6004-6007 (2003).
    • (2003) Cancer Res. , vol.63 , Issue.18 , pp. 6004-6007
    • Kawakami, K.1    Watanabe, G.2
  • 19
    • 0034518362 scopus 로고    scopus 로고
    • Searching expressed sequence tag databases: Discovery and confirmation of a common polymorphism in the thymidylate synthase gene
    • Ulrich CM, Bigler J, Velicer CM, Greene EA, Farin FM, Potter JD: Searching expressed sequence tag databases: discovery and confirmation of a common polymorphism in the thymidylate synthase gene. Cancer Epidemiol. Biomarkers Prev. 9(12), 1381-1385 (2000).
    • (2000) Cancer Epidemiol. Biomarkers Prev. , vol.9 , Issue.12 , pp. 1381-1385
    • Ulrich, C.M.1    Bigler, J.2    Velicer, C.M.3    Greene, E.A.4    Farin, F.M.5    Potter, J.D.6
  • 20
    • 2442480694 scopus 로고    scopus 로고
    • A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels
    • Mandola MV, Stoehlmacher J, Zhang W et al.: A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels. Pharmacogenetics 14(5), 319-327 (2004).
    • (2004) Pharmacogenetics , vol.14 , Issue.5 , pp. 319-327
    • Mandola, M.V.1    Stoehlmacher, J.2    Zhang, W.3
  • 21
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio RB, Harris BE: Clinical pharmacology of 5-fluorouracil. Clin. Pharmacokinet. 16(4), 215-237 (1989).
    • (1989) Clin. Pharmacokinet. , vol.16 , Issue.4 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 22
    • 0030005786 scopus 로고    scopus 로고
    • Link between dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells and liver
    • Chazal M, Etienne MC, Renee N, Bourgeon A, Richelme H, Milano G: Link between dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells and liver. Clin. Cancer Res. 2(3), 507-510 (1996).
    • (1996) Clin. Cancer Res. , vol.2 , Issue.3 , pp. 507-510
    • Chazal, M.1    Etienne, M.C.2    Renee, N.3    Bourgeon, A.4    Richelme, H.5    Milano, G.6
  • 23
    • 0026753035 scopus 로고
    • Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients
    • Fleming RA, Milano G, Thyss A et al.: Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients. Cancer Res. 52(10), 2899-2902 (1992).
    • (1992) Cancer Res. , vol.52 , Issue.10 , pp. 2899-2902
    • Fleming, R.A.1    Milano, G.2    Thyss, A.3
  • 24
    • 0034320204 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase activity and mRNA expression in advanced gastric cancer analysed in relation to effectiveness of preoperative 5-fluorouracil-based chemotherapy
    • Takabayashi A, Iwata S, Kawai Y et al.: Dihydropyrimidine dehydrogenase activity and mRNA expression in advanced gastric cancer analysed in relation to effectiveness of preoperative 5-fluorouracil-based chemotherapy. Int. J. Oncol. 17(5), 889-895 (2000).
    • (2000) Int. J. Oncol. , vol.17 , Issue.5 , pp. 889-895
    • Takabayashi, A.1    Iwata, S.2    Kawai, Y.3
  • 25
    • 15144351973 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer
    • Ridge SA, Sludden J, Wei X et al.: Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer. Br. J. Cancer 77(3), 497-500 (1998).
    • (1998) Br. J. Cancer , vol.77 , Issue.3 , pp. 497-500
    • Ridge, S.A.1    Sludden, J.2    Wei, X.3
  • 26
    • 0029973215 scopus 로고    scopus 로고
    • Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity
    • Wei X, McLeod HL, McMurrough J, Gonzalez FJ, Fernandez-Salguero P: Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity. J. Clin. Invest. 98(3), 610-615 (1996).
    • (1996) J. Clin. Invest. , vol.98 , Issue.3 , pp. 610-615
    • Wei, X.1    McLeod, H.L.2    McMurrough, J.3    Gonzalez, F.J.4    Fernandez-Salguero, P.5
  • 27
    • 0036798968 scopus 로고    scopus 로고
    • High prevalence of the IVS14 + 1G>A mutation in the dihydropyrimidine dehydrogenase gene of patients with severe 5-fluorouracil-associated toxicity
    • Van Kuilenburg AB, Meinsma R, Zoetekouw L, Van Gennip AH: High prevalence of the IVS14 + 1G>A mutation in the dihydropyrimidine dehydrogenase gene of patients with severe 5-fluorouracil-associated toxicity. Pharmacogenetics 12(7), 555-558 (2002).
    • (2002) Pharmacogenetics , vol.12 , Issue.7 , pp. 555-558
    • Van Kuilenburg, A.B.1    Meinsma, R.2    Zoetekouw, L.3    Van Gennip, A.H.4
  • 28
    • 1342301546 scopus 로고    scopus 로고
    • Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: Relationships with 5-fluorouracil sensitivity
    • Etienne MC, Ilc K, Formento JL et al.: Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity. Br. J. Cancer 90(2), 526-534 (2004).
    • (2004) Br. J. Cancer , vol.90 , Issue.2 , pp. 526-534
    • Etienne, M.C.1    Ilc, K.2    Formento, J.L.3
  • 29
    • 1042292043 scopus 로고    scopus 로고
    • Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate
    • Sohn KJ, Croxford R, Yates Z, Lucock M, Kim YI: Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate. J. Natl. Cancer Inst. 96(2), 134-144 (2004).
    • (2004) J. Natl. Cancer Inst. , vol.96 , Issue.2 , pp. 134-144
    • Sohn, K.J.1    Croxford, R.2    Yates, Z.3    Lucock, M.4    Kim, Y.I.5
  • 30
    • 0037990003 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: A novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy
    • Cohen V, Panet-Raymond V, Sabbaghian N, Morin I, Batist G, Rozen R: Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy. Clin. Cancer Res. 9(5), 1611-1615 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , Issue.5 , pp. 1611-1615
    • Cohen, V.1    Panet-Raymond, V.2    Sabbaghian, N.3    Morin, I.4    Batist, G.5    Rozen, R.6
  • 31
    • 85047694201 scopus 로고    scopus 로고
    • Site-specific somatic mitochondrial DNA point mutations in patients with thymidine phosphorylase deficiency
    • Nishigaki Y, Marti R, Copeland WC, Hirano M: Site-specific somatic mitochondrial DNA point mutations in patients with thymidine phosphorylase deficiency. J. Clin. Invest. 111(12), 1913-1921 (2003).
    • (2003) J. Clin. Invest. , vol.111 , Issue.12 , pp. 1913-1921
    • Nishigaki, Y.1    Marti, R.2    Copeland, W.C.3    Hirano, M.4
  • 32
    • 0035749772 scopus 로고
    • Polymorphisms in the ABC drug transporter gene MDR1
    • Brinkmann U, Eichelbaum M: Polymorphisms in the ABC drug transporter gene MDR1. Pharmacogenomics J. 1(1), 59-64 (1993).
    • (1993) Pharmacogenomics J. , vol.1 , Issue.1 , pp. 59-64
    • Brinkmann, U.1    Eichelbaum, M.2
  • 33
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multi-drug resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk O, von Richter O et al.: Functional polymorphisms of the human multi-drug resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA 97(7), 3473-3478 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.7 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    von Richter, O.3
  • 34
    • 0035752933 scopus 로고
    • The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels
    • Kerb R, Aynacioglu AS, Brockmoller J et al.: The predictive value of MDR1, CYP2C9, and CYP2C19 polymorphisms for phenytoin plasma levels. Pharmacogenomics J. 1(3), 204-210 (1904).
    • (1904) Pharmacogenomics J. , vol.1 , Issue.3 , pp. 204-210
    • Kerb, R.1    Aynacioglu, A.S.2    Brockmoller, J.3
  • 35
    • 0036731995 scopus 로고    scopus 로고
    • MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukaemia patients
    • Illmer T, Schuler US, Thiede C et al.: MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukaemia patients. Cancer Res. 62(17), 4955-4962 (2002).
    • (2002) Cancer Res. , vol.62 , Issue.17 , pp. 4955-4962
    • Illmer, T.1    Schuler, U.S.2    Thiede, C.3
  • 36
    • 0041627670 scopus 로고    scopus 로고
    • Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast cancer
    • Kafka A, Sauer G, Jaeger C et al.: Polymorphism C3435T of the MDR-1 gene predicts response to preoperative chemotherapy in locally advanced breast cancer. Int. J. Oncol. 22(5), 1117-1121 (2003).
    • (2003) Int. J. Oncol. , vol.22 , Issue.5 , pp. 1117-1121
    • Kafka, A.1    Sauer, G.2    Jaeger, C.3
  • 37
    • 0028942667 scopus 로고
    • Functional multi-drug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-β-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukaemia
    • Schuurhuis GJ, Broxterman HJ, Ossenkoppele GJ et al.: Functional multi-drug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-β-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukaemia. Clin. Cancer Res. 1(1), 81-93 (1995 ).
    • (1995) Clin. Cancer Res. , vol.1 , Issue.1 , pp. 81-93
    • Schuurhuis, G.J.1    Broxterman, H.J.2    Ossenkoppele, G.J.3
  • 38
    • 0033361943 scopus 로고    scopus 로고
    • Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome
    • Toh S, Wada M, Uchiumi T et al.: Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome. Am. J. Hum. Genet. 64(3), 739-746 (1999).
    • (1999) Am. J. Hum. Genet. , vol.64 , Issue.3 , pp. 739-746
    • Toh, S.1    Wada, M.2    Uchiumi, T.3
  • 39
    • 0035813178 scopus 로고    scopus 로고
    • Identification and functional analysis of two novel mutations in the multi-drug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome
    • Mor-Cohen R, Zivelin A, Rosenberg N, Shani M, Muallem S, Seligsohn U: Identification and functional analysis of two novel mutations in the multi-drug resistance protein 2 gene in Israeli patients with Dubin-Johnson syndrome. J. Biol. Chem. 276(40), 36923-36930 (2001).
    • (2001) J. Biol. Chem. , vol.276 , Issue.40 , pp. 36923-36930
    • Mor-Cohen, R.1    Zivelin, A.2    Rosenberg, N.3    Shani, M.4    Muallem, S.5    Seligsohn, U.6
  • 40
    • 0036206860 scopus 로고    scopus 로고
    • Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: An association between single nucleotide polymorphisms in the 5′-untranslated region and exon 28
    • Itoda M, Saito Y, Soyama A et al.: Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5′-untranslated region and exon 28. Drug Metab. Dispos. 30(4), 363-364 (2002).
    • (2002) Drug Metab. Dispos. , vol.30 , Issue.4 , pp. 363-364
    • Itoda, M.1    Saito, Y.2    Soyama, A.3
  • 41
    • 0028131808 scopus 로고
    • Genetic polymorphisms in xenobiotic metabolism
    • Smith CA, Smith G, Wolf CR: Genetic polymorphisms in xenobiotic metabolism. Eur. J. Cancer 30A(13), 1921-1935 (1994).
    • (1994) Eur. J. Cancer , vol.30 A , Issue.13 , pp. 1921-1935
    • Smith, C.A.1    Smith, G.2    Wolf, C.R.3
  • 42
    • 0028231093 scopus 로고
    • Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism
    • Pemble S, Schroeder KR, Spencer SR et al.: Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem. J. 300(Part 1), 271-276 (1994).
    • (1994) Biochem. J. , vol.300 , Issue.PART 1 , pp. 271-276
    • Pemble, S.1    Schroeder, K.R.2    Spencer, S.R.3
  • 43
    • 0035476887 scopus 로고    scopus 로고
    • Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer
    • Ambrosone CB, Sweeney C, Coles BF et al.: Polymorphisms in glutathione S-transferases (GSTM1 and GSTT1) and survival after treatment for breast cancer. Cancer Res. 61(19), 7130-7135 (2001).
    • (2001) Cancer Res. , vol.61 , Issue.19 , pp. 7130-7135
    • Ambrosone, C.B.1    Sweeney, C.2    Coles, B.F.3
  • 44
    • 0026505943 scopus 로고
    • NAD(P)H: Quinone oxidoreductase gene expression in human colon carcinoma cells: Characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity
    • Traver RD, Horikoshi T, Danenberg KD et al.: NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity. Cancer Res. 52(4), 797-802 (1992).
    • (1992) Cancer Res. , vol.52 , Issue.4 , pp. 797-802
    • Traver, R.D.1    Horikoshi, T.2    Danenberg, K.D.3
  • 45
    • 0032171046 scopus 로고    scopus 로고
    • Role of a DT-diaphorase mutation in the response of anal canal carcinoma to radiation, 5-fluorouracil, and mitomycin C
    • Goldberg ZI, Cummings BJ, Chapman WB, Klamut HJ, Rauth AM: Role of a DT-diaphorase mutation in the response of anal canal carcinoma to radiation, 5-fluorouracil, and mitomycin C. Int. J. Radiat. Oncol. Biol. Phys. 42(2), 331-334 (1998).
    • (1998) Int. J. Radiat. Oncol. Biol. Phys. , vol.42 , Issue.2 , pp. 331-334
    • Goldberg, Z.I.1    Cummings, B.J.2    Chapman, W.B.3    Klamut, H.J.4    Rauth, A.M.5
  • 46
    • 0035892352 scopus 로고    scopus 로고
    • Genotyping of NAD(P)H: Quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: Relationship between genotype status, NQO1 activity and the response of xenografts to mitomycin C chemotherapy in vivo(1)
    • Phillips RM, Burger AM, Fiebig HH, Double JA: Genotyping of NAD(P)H:quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to mitomycin C chemotherapy in vivo(1). Biochem. Pharmacol. 62(10), 1371-1377 (2001).
    • (2001) Biochem. Pharmacol. , vol.62 , Issue.10 , pp. 1371-1377
    • Phillips, R.M.1    Burger, A.M.2    Fiebig, H.H.3    Double, J.A.4
  • 47
    • 0036158312 scopus 로고    scopus 로고
    • Clinical significance of a NAD(P)H: Quinone oxidoreductase 1 polymorphism in patients with disseminated peritoneal cancer receiving intraperitoneal hyperthermic chemotherapy with mitomycin C
    • Fleming RA, Drees J, Loggie BW et al.: Clinical significance of a NAD(P)H: quinone oxidoreductase 1 polymorphism in patients with disseminated peritoneal cancer receiving intraperitoneal hyperthermic chemotherapy with mitomycin C. Pharmacogenetics 12(1), 31-37 (2002).
    • (2002) Pharmacogenetics , vol.12 , Issue.1 , pp. 31-37
    • Fleming, R.A.1    Drees, J.2    Loggie, B.W.3
  • 48
    • 0036928840 scopus 로고    scopus 로고
    • Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukaemia patients intolerant to methotrexate
    • Chiusolo P, Reddiconto G, Casorelli I et al.: Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukaemia patients intolerant to methotrexate. Ann. Oncol. 13(12), 1915-1918 (2002).
    • (2002) Ann. Oncol. , vol.13 , Issue.12 , pp. 1915-1918
    • Chiusolo, P.1    Reddiconto, G.2    Casorelli, I.3
  • 49
    • 0742286981 scopus 로고    scopus 로고
    • High-level multiplex genotyping of polymorphisms involved in folate or homocysteine metabolism by matrix-assisted laser desorption/ionization mass spectrometry
    • Meyer K, Fredriksen A, Ueland PM: High-level multiplex genotyping of polymorphisms involved in folate or homocysteine metabolism by matrix-assisted laser desorption/ionization mass spectrometry. Clin. Chem. 50(2), 391-402 (2004).
    • (2004) Clin. Chem. , vol.50 , Issue.2 , pp. 391-402
    • Meyer, K.1    Fredriksen, A.2    Ueland, P.M.3
  • 50
    • 0036765747 scopus 로고    scopus 로고
    • Thymidylate synthase: A novel genetic determinant of plasma homocysteine and folate levels
    • Trinh BN, Ong CN, Coetzee GA, Yu MC, Laird PW: Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels. Hum. Genet. 111(3), 299-302 (2002).
    • (2002) Hum. Genet. , vol.111 , Issue.3 , pp. 299-302
    • Trinh, B.N.1    Ong, C.N.2    Coetzee, G.A.3    Yu, M.C.4    Laird, P.W.5
  • 51
    • 0037454801 scopus 로고    scopus 로고
    • Effect of methylenetetrahydrofolate reductase 677C-> T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients
    • Toffoli G, Russo A, Innocenti F et al.: Effect of methylenetetrahydrofolate reductase 677C-> T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer patients. Int. J. Cancer 103(3), 294-299 (2003).
    • (2003) Int. J. Cancer , vol.103 , Issue.3 , pp. 294-299
    • Toffoli, G.1    Russo, A.2    Innocenti, F.3
  • 52
    • 0036263469 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses
    • Urano W, Taniguchi A, Yamanaka H et al.: Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses. Pharmacogenetics 12(3), 183-190 (2002).
    • (2002) Pharmacogenetics , vol.12 , Issue.3 , pp. 183-190
    • Urano, W.1    Taniguchi, A.2    Yamanaka, H.3
  • 53
    • 0035412398 scopus 로고    scopus 로고
    • Pharmacogenetics of methotrexate: Toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism
    • Ulrich CM, Yasui Y, Storb R et al.: Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism. Blood 98(1), 231-234 (2001).
    • (2001) Blood , vol.98 , Issue.1 , pp. 231-234
    • Ulrich, C.M.1    Yasui, Y.2    Storb, R.3
  • 54
    • 2142820811 scopus 로고    scopus 로고
    • Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukaemia
    • Robien K, Schubert MM, Bruemmer B, Lloid ME, Potter JD, Ulrich CM: Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukaemia. J. Clin. Oncol. 22(7), 1268-1275 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , Issue.7 , pp. 1268-1275
    • Robien, K.1    Schubert, M.M.2    Bruemmer, B.3    Lloid, M.E.4    Potter, J.D.5    Ulrich, C.M.6
  • 55
    • 0036844903 scopus 로고    scopus 로고
    • Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines
    • Rothem L, Ifergan I, Kaufman Y, Priest DG, Jansen G, Assaraf YG: Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines. Biochem. J. 367(Part 3), 741-750 (2002).
    • (2002) Biochem. J. , vol.367 , Issue.PART 3 , pp. 741-750
    • Rothem, L.1    Ifergan, I.2    Kaufman, Y.3    Priest, D.G.4    Jansen, G.5    Assaraf, Y.G.6
  • 56
    • 0033805360 scopus 로고    scopus 로고
    • A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia
    • Chango A, Emery-Fillon N, de Courcy GP et al.: A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. Mol. Genet. Metab. 70(4), 310-315 (2000).
    • (2000) Mol. Genet. Metab. , vol.70 , Issue.4 , pp. 310-315
    • Chango, A.1    Emery-Fillon, N.2    de Courcy, G.P.3
  • 57
    • 0042914711 scopus 로고    scopus 로고
    • Homocysteine, pharmacogenetics, and neurotoxicity in children with leukaemia
    • Kishi S, Griener J, Cheng C et al.: Homocysteine, pharmacogenetics, and neurotoxicity in children with leukaemia. J. Clin. Oncol. 21(16), 3084-3091 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , Issue.16 , pp. 3084-3091
    • Kishi, S.1    Griener, J.2    Cheng, C.3
  • 58
    • 0034257076 scopus 로고    scopus 로고
    • Glutathione S-transferase-pi gene expression and platinum drug exposure in human lung cancer
    • Oguri T, Fujiwara Y, Katoh O et al.: Glutathione S-transferase-pi gene expression and platinum drug exposure in human lung cancer. Cancer Lett. 156(1), 93-99 (2000).
    • (2000) Cancer Lett. , vol.156 , Issue.1 , pp. 93-99
    • Oguri, T.1    Fujiwara, Y.2    Katoh, O.3
  • 59
    • 0028088048 scopus 로고
    • Naturally-occurring human glutathione S-transferase GSTP1-1 isoforms with isoleucine and valine in position 104 differ in enzymic properties
    • Zimniak P, Nanduri B, Pikula S et al.: Naturally-occurring human glutathione S-transferase GSTP1-1 isoforms with isoleucine and valine in position 104 differ in enzymic properties. Eur. J. Biochem. 224(3), 893-899 (1994).
    • (1994) Eur. J. Biochem. , vol.224 , Issue.3 , pp. 893-899
    • Zimniak, P.1    Nanduri, B.2    Pikula, S.3
  • 60
    • 0037134707 scopus 로고    scopus 로고
    • Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer
    • Stoehlmacher J, Park DJ, Zhang W et al.: Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J. Natl. Cancer Inst. 94(12), 936-942 (2002).
    • (2002) J. Natl. Cancer Inst. , vol.94 , Issue.12 , pp. 936-942
    • Stoehlmacher, J.1    Park, D.J.2    Zhang, W.3
  • 61
    • 0042305238 scopus 로고    scopus 로고
    • Platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma: Glutathione S-transferase genetic polymorphisms as predictive biomarkers of disease outcome
    • Medeiros R, Pereira D, Afonso N et al.: Platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma: glutathione S-transferase genetic polymorphisms as predictive biomarkers of disease outcome. Int. J. Clin. Oncol. 8(3), 156-161 (2003).
    • (2003) Int. J. Clin. Oncol. , vol.8 , Issue.3 , pp. 156-161
    • Medeiros, R.1    Pereira, D.2    Afonso, N.3
  • 62
    • 0034665169 scopus 로고    scopus 로고
    • Pleiotropic resistance to DNA-interactive drugs is associated with increased expression of genes involved in DNA replication, repair, and stress response
    • Levenson VV, Davidovich IA, Roninson IB: Pleiotropic resistance to DNA-interactive drugs is associated with increased expression of genes involved in DNA replication, repair, and stress response. Cancer Res. 60(18), 5027-5030 (2000).
    • (2000) Cancer Res. , vol.60 , Issue.18 , pp. 5027-5030
    • Levenson, V.V.1    Davidovich, I.A.2    Roninson, I.B.3
  • 63
    • 0036907407 scopus 로고    scopus 로고
    • Polymorphisms in DNA repair genes and associations with cancer risk
    • Goode EL, Ulrich CM, Potter JD: Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol Biomarkers Prev. 11(12), 1513-1530 (2002).
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , Issue.12 , pp. 1513-1530
    • Goode, E.L.1    Ulrich, C.M.2    Potter, J.D.3
  • 64
    • 0036490461 scopus 로고    scopus 로고
    • Nucleotide excision repair protein levels vis-a-vis anticancer drug resistance in 60 human tumor cell lines
    • Chen ZP, Malapetsa A, Monks A et al.: Nucleotide excision repair protein levels vis-a-vis anticancer drug resistance in 60 human tumor cell lines. Ai Zheng 21(3), 233-239 (2002).
    • (2002) Ai Zheng , vol.21 , Issue.3 , pp. 233-239
    • Chen, Z.P.1    Malapetsa, A.2    Monks, A.3
  • 65
    • 0032519766 scopus 로고    scopus 로고
    • Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans
    • Shen MR, Jones IM, Mohrenweiser H: Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. Cancer Res. 58(4), 604-608 (1998).
    • (1998) Cancer Res. , vol.58 , Issue.4 , pp. 604-608
    • Shen, M.R.1    Jones, I.M.2    Mohrenweiser, H.3
  • 66
    • 0036247508 scopus 로고    scopus 로고
    • The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk
    • Hou SM, Falt S, Angelini S et al.: The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk. Carcinogenesis 23(4), 599-603 (2002).
    • (2002) Carcinogenesis , vol.23 , Issue.4 , pp. 599-603
    • Hou, S.M.1    Falt, S.2    Angelini, S.3
  • 67
    • 0035893755 scopus 로고    scopus 로고
    • A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer
    • Park DJ, Stoehlmacher J, Zhang W, Tsao-Wei DD, Groshen S, Lenz HJ: A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer. Cancer Res. 61(24), 8654-8658 (2001).
    • (2001) Cancer Res. , vol.61 , Issue.24 , pp. 8654-8658
    • Park, D.J.1    Stoehlmacher, J.2    Zhang, W.3    Tsao-Wei, D.D.4    Groshen, S.5    Lenz, H.J.6
  • 68
    • 0034773290 scopus 로고    scopus 로고
    • Combination of oxaliplatin and irinotecan on human colon cancer cell lines: Activity in vitro and in vivo
    • Guichard S, Arnould S, Hennebelle I, Bugat R, Canal P: Combination of oxaliplatin and irinotecan on human colon cancer cell lines: activity in vitro and in vivo. Anticancer Drugs 12(9), 741-751 (2001).
    • (2001) Anticancer Drugs , vol.12 , Issue.9 , pp. 741-751
    • Guichard, S.1    Arnould, S.2    Hennebelle, I.3    Bugat, R.4    Canal, P.5
  • 69
    • 0031224917 scopus 로고    scopus 로고
    • A nucleotide polymorphism in ERCC1 in human ovarian cancer cell lines and tumor tissues
    • Yu JJ, Mu C, Lee KB et al.: A nucleotide polymorphism in ERCC1 in human ovarian cancer cell lines and tumor tissues. Mutat. Res. 382(1-2), 13-20 (1997).
    • (1997) Mutat. Res. , vol.382 , Issue.1-2 , pp. 13-20
    • Yu, J.J.1    Mu, C.2    Lee, K.B.3
  • 70
    • 0034981858 scopus 로고    scopus 로고
    • Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity
    • Hu JJ, Smith TR, Miller MS, Mohrenweiser HW, Golden A, Case LD: Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity. Carcinogenesis 22(6), 917-922 (2001).
    • (2001) Carcinogenesis , vol.22 , Issue.6 , pp. 917-922
    • Hu, J.J.1    Smith, T.R.2    Miller, M.S.3    Mohrenweiser, H.W.4    Golden, A.5    Case, L.D.6
  • 71
    • 0142124401 scopus 로고    scopus 로고
    • From genotype to phenotype: Correlating XRCC1 polymorphisms with mutagen sensitivity
    • Wang Y, Spitz MR, Zhu Y, Dong Q, Shete S, Wu X: From genotype to phenotype: correlating XRCC1 polymorphisms with mutagen sensitivity. DNA Repair (Amst.) 2(8), 901-908 (2003).
    • (2003) DNA Repair (Amst.) , vol.2 , Issue.8 , pp. 901-908
    • Wang, Y.1    Spitz, M.R.2    Zhu, Y.3    Dong, Q.4    Shete, S.5    Wu, X.6
  • 72
    • 0037455960 scopus 로고    scopus 로고
    • Polymorphisms of XRCC1 and XRCC3 genes and susceptibility to breast cancer
    • Smith TR, Miller MS, Lohman K et al.: Polymorphisms of XRCC1 and XRCC3 genes and susceptibility to breast cancer. Cancer Lett. 190(2), 183-190 (2003).
    • (2003) Cancer Lett. , vol.190 , Issue.2 , pp. 183-190
    • Smith, T.R.1    Miller, M.S.2    Lohman, K.3
  • 73
    • 0035174375 scopus 로고    scopus 로고
    • A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer
    • Stoehlmacher J, Ghaderi V, Iobal S et al.: A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer. Anticancer Res. 21(4B), 3075-3079 (2001).
    • (2001) Anticancer Res. , vol.21 , Issue.4 B , pp. 3075-3079
    • Stoehlmacher, J.1    Ghaderi, V.2    Iobal, S.3
  • 74
    • 0042196122 scopus 로고    scopus 로고
    • Irinotecan pathway genotype analysis to predict pharmacokinetics
    • Mathijssen RH, Marsh S, Karlsson MO et al.: Irinotecan pathway genotype analysis to predict pharmacokinetics. Clin. Cancer Res. 9(9), 3246-3253 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , Issue.9 , pp. 3246-3253
    • Mathijssen, R.H.1    Marsh, S.2    Karlsson, M.O.3
  • 75
    • 0036327586 scopus 로고    scopus 로고
    • Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary
    • Itamochi H, Kigawa J, Sultana H et al.: Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary. Jpn. J. Cancer Res. 93(6), 723-728 (2002).
    • (2002) Jpn. J. Cancer Res. , vol.93 , Issue.6 , pp. 723-728
    • Itamochi, H.1    Kigawa, J.2    Sultana, H.3
  • 76
    • 0033386787 scopus 로고    scopus 로고
    • Significance of multi-drug resistant proteins in predicting chemotherapy response and prognosis in epithelial ovarian cancer
    • Yokoyama Y, Sato S, Fukushi Y, Sakamoto T, Futagami M, Saito Y: Significance of multi-drug resistant proteins in predicting chemotherapy response and prognosis in epithelial ovarian cancer. J. Obstet. Gynaecol. Res. 25(6), 387-394 (1999).
    • (1999) J. Obstet. Gynaecol. Res. , vol.25 , Issue.6 , pp. 387-394
    • Yokoyama, Y.1    Sato, S.2    Fukushi, Y.3    Sakamoto, T.4    Futagami, M.5    Saito, Y.6
  • 77
    • 0032740801 scopus 로고    scopus 로고
    • Drug resistance-associated markers P-glycoprotein, multi-drug resistance-associated protein 1, multi-drug resistance-associated protein 2, and lung resistance protein as prognostic factors in ovarian carcinoma
    • Arts HJ, Katsaros D, de Vries EG et al.: Drug resistance-associated markers P-glycoprotein, multi-drug resistance-associated protein 1, multi-drug resistance-associated protein 2, and lung resistance protein as prognostic factors in ovarian carcinoma. Clin. Cancer Res. 5(10), 2798-2805 (1999).
    • (1999) Clin. Cancer Res. , vol.5 , Issue.10 , pp. 2798-2805
    • Arts, H.J.1    Katsaros, D.2    de Vries, E.G.3
  • 78
    • 0034802132 scopus 로고    scopus 로고
    • Glutathione transferase P1 polymorphism in neuroblastoma studied by endonuclease restriction mapping
    • Bellincampi L, Ballerini S, Bernardini S et al.: Glutathione transferase P1 polymorphism in neuroblastoma studied by endonuclease restriction mapping. Clin. Chem. Lab Med. 39(9), 830-835 (2001).
    • (2001) Clin. Chem. Lab. Med. , vol.39 , Issue.9 , pp. 830-835
    • Bellincampi, L.1    Ballerini, S.2    Bernardini, S.3
  • 79
    • 0030580064 scopus 로고    scopus 로고
    • Conversion of irinotecan (CPT-11) to its active metabolite, Tethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase
    • Rivory LP, Bowles MR, Robert J, Pond SM: Conversion of irinotecan (CPT-11) to its active metabolite, Tethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase. Biochem. Pharmacol. 52(7), 1103-1111 (1996).
    • (1996) Biochem. Pharmacol. , vol.52 , Issue.7 , pp. 1103-1111
    • Rivory, L.P.1    Bowles, M.R.2    Robert, J.3    Pond, S.M.4
  • 80
    • 0025885058 scopus 로고
    • Polymorphisms of human liver carboxylesterases
    • Ketterman AJ: Polymorphisms of human liver carboxylesterases. Biochem. Soc. Trans. 19(1), 306S (1991).
    • (1991) Biochem. Soc. Trans. , vol.19 , Issue.1
    • Ketterman, A.J.1
  • 81
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • Kuehl P, Zhang J, Lin Y et al.: Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat. Genet. 27(4), 383-391 (2001).
    • (2001) Nat. Genet. , vol.27 , Issue.4 , pp. 383-391
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3
  • 82
    • 0032519431 scopus 로고    scopus 로고
    • Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes
    • Iyer L, King CD, Whitington PF et al.: Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J. Clin. Invest. 101(4), 847-854 (1998).
    • (1998) J. Clin. Invest. , vol.101 , Issue.4 , pp. 847-854
    • Iyer, L.1    King, C.D.2    Whitington, P.F.3
  • 83
    • 0033600191 scopus 로고    scopus 로고
    • Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus
    • Ciotti M, Basu N, Brangi M, Owens IS: Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus. Biochem. Biophys. Res. Commun 260(1), 199-202 (1999).
    • (1999) Biochem. Biophys. Res. Commun , vol.260 , Issue.1 , pp. 199-202
    • Ciotti, M.1    Basu, N.2    Brangi, M.3    Owens, I.S.4
  • 84
    • 0030030762 scopus 로고    scopus 로고
    • Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome
    • Monaghan G, Ryan M, Seddon R, Hume R, Burchell B: Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome. Lancet 347(9001), 578-581 (1996).
    • (1996) Lancet , vol.347 , Issue.9001 , pp. 578-581
    • Monaghan, G.1    Ryan, M.2    Seddon, R.3    Hume, R.4    Burchell, B.5
  • 85
    • 0034671387 scopus 로고    scopus 로고
    • Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
    • Ando Y, Saka H, Ando M et al.: Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res. 60(24), 6921-6926 (2000).
    • (2000) Cancer Res. , vol.60 , Issue.24 , pp. 6921-6926
    • Ando, Y.1    Saka, H.2    Ando, M.3
  • 86
  • 87
    • 0036025450 scopus 로고    scopus 로고
    • UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity
    • Iyer L, Das S, Janisch L et al.: UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. Pharmacogenomics J. 2(1), 43-47 (2002).
    • (2002) Pharmacogenomics J. , vol.2 , Issue.1 , pp. 43-47
    • Iyer, L.1    Das, S.2    Janisch, L.3
  • 88
    • 2942527225 scopus 로고    scopus 로고
    • UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer
    • Sai K, Saeki M, Saito Y et al.: UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer. Clin. Pharmacol. Ther. 75(6), 501-515 (2004).
    • (2004) Clin. Pharmacol. Ther. , vol.75 , Issue.6 , pp. 501-515
    • Sai, K.1    Saeki, M.2    Saito, Y.3
  • 89
    • 2342459714 scopus 로고    scopus 로고
    • Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
    • Innocenti F, Undevia SD, Iyer L et al.: Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J. Clin. Oncol. 22(8), 1382-1388 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , Issue.8 , pp. 1382-1388
    • Innocenti, F.1    Undevia, S.D.2    Iyer, L.3
  • 90
    • 0036765309 scopus 로고    scopus 로고
    • Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38)
    • Gagne JF, Montminy V, Belanger P, Journault K, Gaucher G, Guillemette C: Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38). Mol. Pharmacol. 62(3), 608-617 (2002).
    • (2002) Mol. Pharmacol. , vol.62 , Issue.3 , pp. 608-617
    • Gagne, J.F.1    Montminy, V.2    Belanger, P.3    Journault, K.4    Gaucher, G.5    Guillemette, C.6
  • 91
    • 0036207164 scopus 로고    scopus 로고
    • Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice
    • Iyer L, Ramirez J, Shepard DR et al.: Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice. Cancer Chemother. Pharmacol. 49(4), 336-341 (2002).
    • (2002) Cancer Chemother. Pharmacol. , vol.49 , Issue.4 , pp. 336-341
    • Iyer, L.1    Ramirez, J.2    Shepard, D.R.3
  • 92
    • 0028201724 scopus 로고
    • Cytochrome P450 3A-mediated human liver microsomal taxol 6 α-hydroxylation
    • Kumar GN, Walle UK, Walle T: Cytochrome P450 3A-mediated human liver microsomal taxol 6 α-hydroxylation. J. Pharmacol. Exp. Ther. 268(3), 1160-1165 (1994).
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , Issue.3 , pp. 1160-1165
    • Kumar, G.N.1    Walle, U.K.2    Walle, T.3
  • 93
    • 0034791777 scopus 로고    scopus 로고
    • Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid
    • Dai D, Zeldin DC, Blaisdell JA et al.: Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid. Pharmacogenetics 11(7), 597-607 (2001).
    • (2001) Pharmacogenetics , vol.11 , Issue.7 , pp. 597-607
    • Dai, D.1    Zeldin, D.C.2    Blaisdell, J.A.3
  • 94
    • 0036731724 scopus 로고    scopus 로고
    • Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies
    • Goh BC, Lee SC, Wang LZ et al.: Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies. J. Clin. Oncol. 20(17), 3683-3690 (2002).
    • (2002) J. Clin. Oncol. , vol.20 , Issue.17 , pp. 3683-3690
    • Goh, B.C.1    Lee, S.C.2    Wang, L.Z.3
  • 95
    • 0036351238 scopus 로고    scopus 로고
    • Multi-drug resistance gene-1 is a useful predictor of paclitaxel-based chemotherapy for patients with ovarian cancer
    • Kamazawa S, Kigawa J, Kanamori Y et al.: Multi-drug resistance gene-1 is a useful predictor of paclitaxel-based chemotherapy for patients with ovarian cancer. Gynecol. Oncol. 86(2), 171-176 (2002).
    • (2002) Gynecol. Oncol. , vol.86 , Issue.2 , pp. 171-176
    • Kamazawa, S.1    Kigawa, J.2    Kanamori, Y.3
  • 96
    • 0037282898 scopus 로고    scopus 로고
    • Predicting chemotherapy response to paclitaxel-based therapy in advanced non-small-cell lung cancer with P-glycoprotein expression
    • Yeh JJ, Hsu WH, Wang JJ, Ho ST, Kao A: Predicting chemotherapy response to paclitaxel-based therapy in advanced non-small-cell lung cancer with P-glycoprotein expression. Respiration 70(1), 32-35 (2003).
    • (2003) Respiration , vol.70 , Issue.1 , pp. 32-35
    • Yeh, J.J.1    Hsu, W.H.2    Wang, J.J.3    Ho, S.T.4    Kao, A.5
  • 97
    • 0842286886 scopus 로고    scopus 로고
    • Cancer pharmacogenetics
    • Marsh S, McLeod HL: Cancer pharmacogenetics. Br. J. Cancer 90(1), 8-11 (2004).
    • (2004) Br. J. Cancer , vol.90 , Issue.1 , pp. 8-11
    • Marsh, S.1    McLeod, H.L.2
  • 98
    • 0034808681 scopus 로고    scopus 로고
    • Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls
    • Raida M, Schwabe W, Hausler P et al.: Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5′-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls. Clin. Cancer Res. 7(9), 2832-2839 (2001).
    • (2001) Clin. Cancer Res. , vol.7 , Issue.9 , pp. 2832-2839
    • Raida, M.1    Schwabe, W.2    Hausler, P.3
  • 99
    • 0008175035 scopus 로고    scopus 로고
    • Analysis of negatively 'charge tagged' DNA by MALDI-TOF MS
    • Berlin K, Gut IG: Analysis of negatively 'charge tagged' DNA by MALDI-TOF MS. Rapid Commun. Mass Spectrom. 13, 1339-1343. 1999.
    • (1999) Rapid Commun. Mass Spectrom. , vol.13 , pp. 1339-1343
    • Berlin, K.1    Gut, I.G.2
  • 100
    • 0141891812 scopus 로고    scopus 로고
    • Evaluation of a microarray for genotyping polymorphisms related to xenobiotic metabolism and DNA repair
    • Landi S, Gemignani F, Gioia-Patricola L, Chabrier A, Canzian F: Evaluation of a microarray for genotyping polymorphisms related to xenobiotic metabolism and DNA repair. Biotechniques 35(4), 816-817 (2003).
    • (2003) Biotechniques , vol.35 , Issue.4 , pp. 816-817
    • Landi, S.1    Gemignani, F.2    Gioia-Patricola, L.3    Chabrier, A.4    Canzian, F.5
  • 101
    • 0036162826 scopus 로고    scopus 로고
    • Angiogenesis as a target for gastric cancer
    • Kakeji Y, Maehara Y, Sumiyoshi Y, Oda S, Emi Y: Angiogenesis as a target for gastric cancer. Surgery 131(Suppl. 1), S48-S54 (2002).
    • (2002) Surgery , vol.131 , Issue.SUPPL. 1
    • Kakeji, Y.1    Maehara, Y.2    Sumiyoshi, Y.3    Oda, S.4    Emi, Y.5
  • 102
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R et al.: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 350(21), 2129-2139 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , Issue.21 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 103
    • 0038349954 scopus 로고    scopus 로고
    • Biologists take tentative steps towards bespoke cancer drugs
    • Cyranoski D: Biologists take tentative steps towards bespoke cancer drugs. Nature 423(6937), 209 (2003).
    • (2003) Nature , vol.423 , Issue.6937 , pp. 209
    • Cyranoski, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.