-
1
-
-
0024472695
-
Purification and characterization of dihydropyrimidine dehydrogenase from pig liver
-
Podschun, B., Wahler, G., and Schnackerz, K. D. Purification and characterization of dihydropyrimidine dehydrogenase from pig liver. Eur. J. Biochem., 185: 219-224, 1989.
-
(1989)
Eur. J. Biochem.
, vol.185
, pp. 219-224
-
-
Podschun, B.1
Wahler, G.2
Schnackerz, K.D.3
-
2
-
-
0022400840
-
Enzymes of uracil catabolism in normal and neoplastic human tissues
-
Naguib, F. N M., El Kouni, M. H., and Cha, S. Enzymes of uracil catabolism in normal and neoplastic human tissues. Cancer Res., 45: 5402-5412, 1985.
-
(1985)
Cancer Res.
, vol.45
, pp. 5402-5412
-
-
Naguib, F.N.M.1
El Kouni, M.H.2
Cha, S.3
-
3
-
-
0022263834
-
Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity
-
Tuchman, M., Stoekeler, J. S., Klang, D. T., O'Dea, R., Ramnaraine, M. L., and Mirkin, B. L. Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity. N. Engl. J. Med., 313: 245-249, 1985.
-
(1985)
N. Engl. J. Med.
, vol.313
, pp. 245-249
-
-
Tuchman, M.1
Stoekeler, J.S.2
Klang, D.T.3
O'Dea, R.4
Ramnaraine, M.L.5
Mirkin, B.L.6
-
4
-
-
0023902287
-
Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil induced toxicity
-
Diasio, R. B., Beavers, T. L., and Carpenter, J. T. Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil induced toxicity. J. Clin. Invest., 81: 47-51, 1988.
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 47-51
-
-
Diasio, R.B.1
Beavers, T.L.2
Carpenter, J.T.3
-
5
-
-
0025990479
-
Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome
-
Phila.
-
Harris, B. E., Carpenter, J. T., and Diasio, R. B. Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome. Cancer (Phila.), 68: 499-501, 1991.
-
(1991)
Cancer
, vol.68
, pp. 499-501
-
-
Harris, B.E.1
Carpenter, J.T.2
Diasio, R.B.3
-
6
-
-
0027496582
-
Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency
-
Houyau, P., Gay, C., Chatelut, E., Canal, P., Roché, H., and Milano, G. Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency. J. Natl. Cancer Inst , 85: 1602-1603, 1993.
-
(1993)
J. Natl. Cancer Inst
, vol.85
, pp. 1602-1603
-
-
Houyau, P.1
Gay, C.2
Chatelut, E.3
Canal, P.4
Roché, H.5
Milano, G.6
-
7
-
-
0027534425
-
Dihydropyrimidine dehydrogenase activity in cancer patients
-
Fleming, R. A , Milano, G., Gaspard, M. H , Bargnoux, P. J., Thyss, A., Plagne, R., Renée, N., Schneider, M., and Demard, F. Dihydropyrimidine dehydrogenase activity in cancer patients. Eur. J. Cancer, 29: 740-744, 1993.
-
(1993)
Eur. J. Cancer
, vol.29
, pp. 740-744
-
-
Fleming, R.A.1
Milano, G.2
Gaspard, M.H.3
Bargnoux, P.J.4
Thyss, A.5
Plagne, R.6
Renée, N.7
Schneider, M.8
Demard, F.9
-
8
-
-
0027426408
-
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients and clinical implication in 5-fluorouracil chemotherapy
-
Lu, Z., Zhang, R., and Diasio, R. B. Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients and clinical implication in 5-fluorouracil chemotherapy. Cancer Res., 53. 5433-5438, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 5433-5438
-
-
Lu, Z.1
Zhang, R.2
Diasio, R.B.3
-
9
-
-
0028006858
-
Population study of dihydropyrimidine dehydrogenase in cancer patients
-
Etienne, M. C., Lagrange, J. L., Dassonville, O., Fleming, R., Thyss, A., Renée, N., Schneider, M., Demard, F., and Milano, G. Population study of dihydropyrimidine dehydrogenase in cancer patients. J. Clin. Oncol., 12: 2248-2253, 1994.
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 2248-2253
-
-
Etienne, M.C.1
Lagrange, J.L.2
Dassonville, O.3
Fleming, R.4
Thyss, A.5
Renée, N.6
Schneider, M.7
Demard, F.8
Milano, G.9
-
10
-
-
0025058867
-
Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protacted continuous infusion
-
Harris, B. E., Song, R., Soong, S., and Diasio, R. B. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protacted continuous infusion. Cancer Res., 50: 197-201, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 197-201
-
-
Harris, B.E.1
Song, R.2
Soong, S.3
Diasio, R.B.4
-
11
-
-
0026753035
-
Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients
-
Fleming, R. A., Milano, G., Thyss, A., Etienne, M. C., Renée, N., Schneider, M., and Demard, F. Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients. Cancer Res., 52: 2899-2902, 1992
-
(1992)
Cancer Res.
, vol.52
, pp. 2899-2902
-
-
Fleming, R.A.1
Milano, G.2
Thyss, A.3
Etienne, M.C.4
Renée, N.5
Schneider, M.6
Demard, F.7
-
12
-
-
0024595925
-
Clinical pharmacology of 5-fluorouracil
-
Diasio, R. B., and Harris, B E Clinical pharmacology of 5-fluorouracil. Clin. Pharmacokinet., 16: 215-237, 1989.
-
(1989)
Clin. Pharmacokinet.
, vol.16
, pp. 215-237
-
-
Diasio, R.B.1
Harris, B.E.2
-
13
-
-
0028559551
-
Potential importance of dihydropyrimidine dehydrogenase in cancer chemotherapy
-
Milano, G., and Etienne, M. C. Potential importance of dihydropyrimidine dehydrogenase in cancer chemotherapy. Pharmacogenetics, 4: 301-306, 1994.
-
(1994)
Pharmacogenetics
, vol.4
, pp. 301-306
-
-
Milano, G.1
Etienne, M.C.2
-
14
-
-
0027945196
-
Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy
-
Diasio, R. B., and Lu, Z. Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy. J. Clin. Oncol., 12: 2239-2242, 1994.
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 2239-2242
-
-
Diasio, R.B.1
Lu, Z.2
-
15
-
-
0024512054
-
5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer
-
Santini, J , Milano, G., Thyss, A., Renée, N., Viens, P. Ayela, P., Schneider, M., and Demard, F. 5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer. Br. J. Cancer, 59: 287-290, 1989.
-
(1989)
Br. J. Cancer
, vol.59
, pp. 287-290
-
-
Santini, J.1
Milano, G.2
Thyss, A.3
Renée, N.4
Viens, P.5
Ayela, P.6
Schneider, M.7
Demard, F.8
-
16
-
-
0026079516
-
Pharmacokinetic and pharmacodynamic analysis of 5-fluorouracil during 72 hour continuous infusion with and without dipyridamole
-
Trump, D. L., Egorin, M J., Forrest, A , Willson, J. K., Remick, S., and Tutsch, K. Pharmacokinetic and pharmacodynamic analysis of 5-fluorouracil during 72 hour continuous infusion with and without dipyridamole. J. Clin. Oncol., 9: 2027-2037, 1991.
-
(1991)
J. Clin. Oncol.
, vol.9
, pp. 2027-2037
-
-
Trump, D.L.1
Egorin, M.J.2
Forrest, A.3
Willson, J.K.4
Remick, S.5
Tutsch, K.6
-
17
-
-
0028357629
-
Relationship between fluorouracil systemic exposure and tumor response and patient survival
-
Milano, G., Etienne, M. C , Renée, N., Thyss, A., Schneider, M., Ramaioli, A., and Demard, F. Relationship between fluorouracil systemic exposure and tumor response and patient survival. J. Clin. Oncol., 12: 1291-1295, 1994.
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 1291-1295
-
-
Milano, G.1
Etienne, M.C.2
Renée, N.3
Thyss, A.4
Schneider, M.5
Ramaioli, A.6
Demard, F.7
-
18
-
-
9044234514
-
Initial molecular characterization of human dihydropyrimidine dehydrogenase deficiency a pharmacogenetic syndrome predisposing to severe 5-fluorouracil toxicity
-
Albin, N., Johnson, M. R., Shahinian, H., Wang, K., and Diasio, R. B. Initial molecular characterization of human dihydropyrimidine dehydrogenase deficiency a pharmacogenetic syndrome predisposing to severe 5-fluorouracil toxicity. Proc. ASCO, 14: 420, 1995.
-
(1995)
Proc. ASCO
, vol.14
, pp. 420
-
-
Albin, N.1
Johnson, M.R.2
Shahinian, H.3
Wang, K.4
Diasio, R.B.5
-
19
-
-
9044221470
-
Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities
-
in press
-
Stephan, F., Etienne, M. C., Wallays, C., Milano, G., and Clergue, F. Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities. Am. J. Med., in press, 1996.
-
(1996)
Am. J. Med.
-
-
Stephan, F.1
Etienne, M.C.2
Wallays, C.3
Milano, G.4
Clergue, F.5
-
20
-
-
0027297227
-
Comparison of dihydropyrimidine dehydrogenase from human, rat, pig and cow liver. Biochemical and immunological properties
-
Lu, Z. H., Zhang, R , and Diasio, R. B. Comparison of dihydropyrimidine dehydrogenase from human, rat, pig and cow liver. Biochemical and immunological properties Biochem. Pharmacol., 46: 945-952, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 945-952
-
-
Lu, Z.H.1
Zhang, R.2
Diasio, R.B.3
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