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Volumn 2, Issue 3, 1996, Pages 507-510

Link between dihydropyrimidine dehydrogenase activity in peripheral blood mononuclear cells and liver

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL;

EID: 0030005786     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (107)

References (20)
  • 1
    • 0024472695 scopus 로고
    • Purification and characterization of dihydropyrimidine dehydrogenase from pig liver
    • Podschun, B., Wahler, G., and Schnackerz, K. D. Purification and characterization of dihydropyrimidine dehydrogenase from pig liver. Eur. J. Biochem., 185: 219-224, 1989.
    • (1989) Eur. J. Biochem. , vol.185 , pp. 219-224
    • Podschun, B.1    Wahler, G.2    Schnackerz, K.D.3
  • 2
    • 0022400840 scopus 로고
    • Enzymes of uracil catabolism in normal and neoplastic human tissues
    • Naguib, F. N M., El Kouni, M. H., and Cha, S. Enzymes of uracil catabolism in normal and neoplastic human tissues. Cancer Res., 45: 5402-5412, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 5402-5412
    • Naguib, F.N.M.1    El Kouni, M.H.2    Cha, S.3
  • 4
    • 0023902287 scopus 로고
    • Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil induced toxicity
    • Diasio, R. B., Beavers, T. L., and Carpenter, J. T. Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil induced toxicity. J. Clin. Invest., 81: 47-51, 1988.
    • (1988) J. Clin. Invest. , vol.81 , pp. 47-51
    • Diasio, R.B.1    Beavers, T.L.2    Carpenter, J.T.3
  • 5
    • 0025990479 scopus 로고
    • Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome
    • Phila.
    • Harris, B. E., Carpenter, J. T., and Diasio, R. B. Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome. Cancer (Phila.), 68: 499-501, 1991.
    • (1991) Cancer , vol.68 , pp. 499-501
    • Harris, B.E.1    Carpenter, J.T.2    Diasio, R.B.3
  • 6
    • 0027496582 scopus 로고
    • Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency
    • Houyau, P., Gay, C., Chatelut, E., Canal, P., Roché, H., and Milano, G. Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency. J. Natl. Cancer Inst , 85: 1602-1603, 1993.
    • (1993) J. Natl. Cancer Inst , vol.85 , pp. 1602-1603
    • Houyau, P.1    Gay, C.2    Chatelut, E.3    Canal, P.4    Roché, H.5    Milano, G.6
  • 8
    • 0027426408 scopus 로고
    • Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients and clinical implication in 5-fluorouracil chemotherapy
    • Lu, Z., Zhang, R., and Diasio, R. B. Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients and clinical implication in 5-fluorouracil chemotherapy. Cancer Res., 53. 5433-5438, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 5433-5438
    • Lu, Z.1    Zhang, R.2    Diasio, R.B.3
  • 10
    • 0025058867 scopus 로고
    • Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protacted continuous infusion
    • Harris, B. E., Song, R., Soong, S., and Diasio, R. B. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protacted continuous infusion. Cancer Res., 50: 197-201, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 197-201
    • Harris, B.E.1    Song, R.2    Soong, S.3    Diasio, R.B.4
  • 11
    • 0026753035 scopus 로고
    • Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients
    • Fleming, R. A., Milano, G., Thyss, A., Etienne, M. C., Renée, N., Schneider, M., and Demard, F. Correlation between dihydropyrimidine dehydrogenase activity in peripheral mononuclear cells and systemic clearance of fluorouracil in cancer patients. Cancer Res., 52: 2899-2902, 1992
    • (1992) Cancer Res. , vol.52 , pp. 2899-2902
    • Fleming, R.A.1    Milano, G.2    Thyss, A.3    Etienne, M.C.4    Renée, N.5    Schneider, M.6    Demard, F.7
  • 12
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio, R. B., and Harris, B E Clinical pharmacology of 5-fluorouracil. Clin. Pharmacokinet., 16: 215-237, 1989.
    • (1989) Clin. Pharmacokinet. , vol.16 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 13
    • 0028559551 scopus 로고
    • Potential importance of dihydropyrimidine dehydrogenase in cancer chemotherapy
    • Milano, G., and Etienne, M. C. Potential importance of dihydropyrimidine dehydrogenase in cancer chemotherapy. Pharmacogenetics, 4: 301-306, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 301-306
    • Milano, G.1    Etienne, M.C.2
  • 14
    • 0027945196 scopus 로고
    • Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy
    • Diasio, R. B., and Lu, Z. Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy. J. Clin. Oncol., 12: 2239-2242, 1994.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 2239-2242
    • Diasio, R.B.1    Lu, Z.2
  • 15
    • 0024512054 scopus 로고
    • 5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer
    • Santini, J , Milano, G., Thyss, A., Renée, N., Viens, P. Ayela, P., Schneider, M., and Demard, F. 5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer. Br. J. Cancer, 59: 287-290, 1989.
    • (1989) Br. J. Cancer , vol.59 , pp. 287-290
    • Santini, J.1    Milano, G.2    Thyss, A.3    Renée, N.4    Viens, P.5    Ayela, P.6    Schneider, M.7    Demard, F.8
  • 16
    • 0026079516 scopus 로고
    • Pharmacokinetic and pharmacodynamic analysis of 5-fluorouracil during 72 hour continuous infusion with and without dipyridamole
    • Trump, D. L., Egorin, M J., Forrest, A , Willson, J. K., Remick, S., and Tutsch, K. Pharmacokinetic and pharmacodynamic analysis of 5-fluorouracil during 72 hour continuous infusion with and without dipyridamole. J. Clin. Oncol., 9: 2027-2037, 1991.
    • (1991) J. Clin. Oncol. , vol.9 , pp. 2027-2037
    • Trump, D.L.1    Egorin, M.J.2    Forrest, A.3    Willson, J.K.4    Remick, S.5    Tutsch, K.6
  • 17
  • 18
    • 9044234514 scopus 로고
    • Initial molecular characterization of human dihydropyrimidine dehydrogenase deficiency a pharmacogenetic syndrome predisposing to severe 5-fluorouracil toxicity
    • Albin, N., Johnson, M. R., Shahinian, H., Wang, K., and Diasio, R. B. Initial molecular characterization of human dihydropyrimidine dehydrogenase deficiency a pharmacogenetic syndrome predisposing to severe 5-fluorouracil toxicity. Proc. ASCO, 14: 420, 1995.
    • (1995) Proc. ASCO , vol.14 , pp. 420
    • Albin, N.1    Johnson, M.R.2    Shahinian, H.3    Wang, K.4    Diasio, R.B.5
  • 19
    • 9044221470 scopus 로고    scopus 로고
    • Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities
    • in press
    • Stephan, F., Etienne, M. C., Wallays, C., Milano, G., and Clergue, F. Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities. Am. J. Med., in press, 1996.
    • (1996) Am. J. Med.
    • Stephan, F.1    Etienne, M.C.2    Wallays, C.3    Milano, G.4    Clergue, F.5
  • 20
    • 0027297227 scopus 로고
    • Comparison of dihydropyrimidine dehydrogenase from human, rat, pig and cow liver. Biochemical and immunological properties
    • Lu, Z. H., Zhang, R , and Diasio, R. B. Comparison of dihydropyrimidine dehydrogenase from human, rat, pig and cow liver. Biochemical and immunological properties Biochem. Pharmacol., 46: 945-952, 1993.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 945-952
    • Lu, Z.H.1    Zhang, R.2    Diasio, R.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.