Identification and Functional Analysis of Two Novel Mutations in the Multidrug Resistance Protein 2 Gene in Israeli Patients with Dubin-Johnson Syndrome

Journal of Biological Chemistry

Volumn 276, Issue 40, 2001, Pages 36923-36930

  Mor Cohen, Ronit ^a,b   Zivelin, Ariella ^a   Rosenberg, Nurit ^a   Shani, Mordechai ^a   Muallem, Shmuel ^b   Seligsohn, Uri ^a,c  

^a TEL AVIV UNIVERSITY   (Israel)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c SHEBA MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; DNA SEQUENCES; DRUG DOSAGE; ENZYME KINETICS; GENES; IMMUNOLOGY; PROTEINS;

IMMUNOBLOT ANALYSIS; IMMUNOCYTOCHEMISTRY;

MUTAGENESIS;

ADENINE; CARBOXYFLUORESCEIN; MULTIDRUG RESISTANCE PROTEIN 2; PROBENECID; THYMINE; 6 CARBOXYFLUORESCEIN; 6-CARBOXYFLUORESCEIN; CARRIER PROTEIN; FLUORESCEIN DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2;

APICAL MEMBRANE; ARTICLE; CELL STRAIN HEK 293; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; DUBIN JOHNSON SYNDROME; ENDOPLASMIC RETICULUM; EXON; EXPRESSION VECTOR; FLUORESCENCE ANALYSIS; FLUORESCENCE TRANSPORT ASSAY; FOUNDER EFFECT; GENE EXPRESSION; GENE MUTATION; GENETIC DISORDER; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; HAPLOTYPE; HOMOZYGOSITY; HUMAN; HUMAN CELL; HYPERBILIRUBINEMIA; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IRAN; ISRAEL; JEW; LIVER CELL; MOROCCO; MULTIDRUG RESISTANCE PROTEIN 2 GENE; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; SITE DIRECTED MUTAGENESIS; CELL CULTURE; CELL FRACTIONATION; ETHNOLOGY; GENETICS; JAUNDICE; METABOLISM; MUTATION; PEDIGREE; TRANSPORT AT THE CELLULAR LEVEL;

IRANIA; VECTORS;

BIOLOGICAL TRANSPORT; CELLS, CULTURED; FLUORESCEINS; HUMANS; IRAN; ISRAEL; JAUNDICE, CHRONIC IDIOPATHIC; JEWS; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; PEDIGREE; POLYMORPHISM, GENETIC; SUBCELLULAR FRACTIONS;

EID: 0035813178     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105047200     Document Type: Article

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