-
1
-
-
0346728473
-
Systematic genome-wide screens of gene function
-
A.E. Carpenter and D.M. Sabatini. Systematic genome-wide screens of gene function, Nature Review., 2004, 5: 11-21.
-
(2004)
Nature Review
, vol.5
, pp. 11-21
-
-
Carpenter, A.E.1
Sabatini, D.M.2
-
2
-
-
0141569812
-
Interfering with disease: Opportunities and roadblocks to harnessing RNA interference
-
J. Lieberman, E. Song, S.K. Lee, and P. Shankar. Interfering with disease: opportunities and roadblocks to harnessing RNA interference, Trends Mol. Med., 2003, 9: 397-403.
-
(2003)
Trends Mol. Med.
, vol.9
, pp. 397-403
-
-
Lieberman, J.1
Song, E.2
Lee, S.K.3
Shankar, P.4
-
3
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
-
T. Holen, M. Amarzguioui, M.T. Wiiger, E. Babaie, and H. Prydz. Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor, Nucleic Acids Res., 2002, 30: 1757-1766.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 1757-1766
-
-
Holen, T.1
Amarzguioui, M.2
Wiiger, M.T.3
Babaie, E.4
Prydz, H.5
-
4
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
J. Harborth, S.M. Elbashir. K. Vandenburgh, H. Manninga, S.A. Scaringe, K. Weber, and T. Tuschl, Sequence, Chemical, and Structural Variation of Small Interfering RNAs and Short Hairpin RNAs and the Effect on Mammalian Gene Silencing, Antisense Nucleic Acid Drug Dev., 2003, 13: 83-105.
-
(2003)
Antisense Nucleic Acid Drug Dev.
, vol.13
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
Manninga, H.4
Scaringe, S.A.5
Weber, K.6
Tuschl, T.7
-
5
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl, Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells, Nature, 2001, 411: 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
6
-
-
0037470145
-
Efficient reduction of target RNAs by small interfering RNA and RNase H- Dependent antisense agents: A comparative analysis
-
T.A. Vickers, S. Koo, C.F. Bennett, S.T. Crooke, N.M. Dean, and B.F. Baker, Efficient reduction of target RNAs by small interfering RNA and RNase H- dependent antisense agents: A comparative analysis, J. Biol. Chem., 2003, 278: 7108-7118.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7108-7118
-
-
Vickers, T.A.1
Koo, S.2
Bennett, C.F.3
Crooke, S.T.4
Dean, N.M.5
Baker, B.F.6
-
7
-
-
0037327444
-
SiRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells
-
H. Kawasaki, E. Suyama, M. Iyo, and K. Taira, siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells, Nucleic Acids Res., 2003, 31: 981-987.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 981-987
-
-
Kawasaki, H.1
Suyama, E.2
Iyo, M.3
Taira, K.4
-
8
-
-
0038521255
-
The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF 1R transcript
-
E.A. Bohula,E, A.J. Salisbury, M. Sohail, M.P. Playford, J. Riedemann, E.M. Southern, and V.M. Macaulay, The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF 1R transcript. J. Biol. Chem., 2003, 278: 15991-15997.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15991-15997
-
-
Bohula, E.A.1
Salisbury, A.J.2
Sohail, M.3
Playford, M.P.4
Riedemann, J.5
Southern, E.M.6
Macaulay, V.M.7
-
9
-
-
0042161890
-
The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides
-
F.R. Kretschmer-Kazemi, and G. Sczakiel, The activity of siRNA in mammalian cells is related to structural target accessibility: a comparison with antisense oligonucleotides, Nucleic Acids Res., 2003, 31: 4417-4424.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 4417-4424
-
-
Kretschmer-Kazemi, F.R.1
Sczakiel, G.2
-
10
-
-
0035798415
-
ATP requirements and small interfering RNA structure in the RNA interference pathway
-
A. Nykanen, B. Haley, and P.D. Zamore, ATP requirements and small interfering RNA structure in the RNA interference pathway, Cell, 2001, 107: 309-321.
-
(2001)
Cell
, vol.107
, pp. 309-321
-
-
Nykanen, A.1
Haley, B.2
Zamore, P.D.3
-
11
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
J. Martinez, A. Patkaniowska, H. Urlaub, R. Luhrmann, and T. Tuschl, Single-stranded antisense siRNAs guide target RNA cleavage in RNAi, Cell, 2002, 110: 563-574.
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
12
-
-
0036752955
-
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
-
D.S. Schwarz, G. Hutvagner, B. Haley, and P.D. Zamore, Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways, Mol. Cell., 2002, 10: 537-548.
-
(2002)
Mol. Cell.
, vol.10
, pp. 537-548
-
-
Schwarz, D.S.1
Hutvagner, G.2
Haley, B.3
Zamore, P.D.4
-
13
-
-
0037144546
-
A micro RNA in a multiple-turnover RNAi enzyme complex
-
G. Hutvagner, and P.D. Zamore, A micro RNA in a multiple-turnover RNAi enzyme complex, Science, 2002, 297: 2056-2060.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
14
-
-
0035900651
-
(2001) on the role of RNA amplification in dsRNA-triggered gene silencing
-
T. Sijen, J. Fleenor, F. Simmer, K.L. Thijssen, S. Parrish, L. Timmons, R.H. Plasterk, and A. Fire, (2001) On the role of RNA amplification in dsRNA-triggered gene silencing. Cell, 2001, 107: 465-476.
-
(2001)
Cell
, vol.107
, pp. 465-476
-
-
Sijen, T.1
Fleenor, J.2
Simmer, F.3
Thijssen, K.L.4
Parrish, S.5
Timmons, L.6
Plasterk, R.H.7
Fire, A.8
-
15
-
-
0037169034
-
RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs
-
M. Tijsterman, R.F. Ketting, K.L. Okihara, T. Sijen, and R.H. Plasterk, RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs. Science, 2002, 295: 694-697.
-
(2002)
Science
, vol.295
, pp. 694-697
-
-
Tijsterman, M.1
Ketting, R.F.2
Okihara, K.L.3
Sijen, T.4
Plasterk, R.H.5
-
16
-
-
0034673638
-
An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells
-
S.M., Hammond, E. Bernstein, D. Beach, and G.J. Hannon, An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells. Nature, 2000, 404: 293-296.
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
17
-
-
0035182648
-
Concepts to automate the theoretical design of effective antisense oligonucleotides
-
R.K. Far, W. Nedbal, and G. Sczakiel, Concepts to automate the theoretical design of effective antisense oligonucleotides, Bioinformatics, 2001, 17: 1058-1061.
-
(2001)
Bioinformatics
, vol.17
, pp. 1058-1061
-
-
Far, R.K.1
Nedbal, W.2
Sczakiel, G.3
-
18
-
-
0034653783
-
(2000) Effects of RNA secondary structure on cellular antisense activity
-
T.A. Vickers, J.R. Wyatt, and S.M. Freier, (2000) Effects of RNA secondary structure on cellular antisense activity, Nucleic Acids Res., 2000, 28: 1340-1347.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 1340-1347
-
-
Vickers, T.A.1
Wyatt, J.R.2
Freier, S.M.3
-
19
-
-
0035283171
-
Statistical prediction of single-stranded regions in RNA secondary structure and application to predicting effective antisense target sites and beyond
-
Y. Ding, and C.E. Lawrence, Statistical prediction of single-stranded regions in RNA secondary structure and application to predicting effective antisense target sites and beyond, Nucleic Acids Res., 2001, 29: 1034-1046.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 1034-1046
-
-
Ding, Y.1
Lawrence, C.E.2
-
20
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
M. Zuker, Mfold web server for nucleic acid folding and hybridization prediction, Nucleic Acids Res., 2003, 31: 3406-3415.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
-
21
-
-
0003576417
-
-
Springer- Verlag, New York Inc, New York, NY
-
Burnham,K.P and Anderson,D.R., Model selection and interference: A Practical Information - Theoretic Approach. Springer- Verlag, New York Inc, New York, NY, 1998.
-
(1998)
Model Selection and Interference: A Practical Information - Theoretic Approach
-
-
Burnham, K.P.1
Anderson, D.R.2
-
22
-
-
0037132736
-
Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells
-
B. Spankuch-Schmitt, J. Bereiter-Hahn, M. Kaufmann, and K. Strebhardt, Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells, J. Natl. Cancer Inst., 2002, 94: 1863-1877.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 1863-1877
-
-
Spankuch-Schmitt, B.1
Bereiter-Hahn, J.2
Kaufmann, M.3
Strebhardt, K.4
-
23
-
-
0036727416
-
Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
-
D.L. Lewis, J.E. Hagstrom, A.G. Loomis, J.A. Wolff, and H. Herweijer, Efficient delivery of siRNA for inhibition of gene expression in postnatal mice, Nat. Genet., 2002, 32: 107-108.
-
(2002)
Nat. Genet.
, vol.32
, pp. 107-108
-
-
Lewis, D.L.1
Hagstrom, J.E.2
Loomis, A.G.3
Wolff, J.A.4
Herweijer, H.5
-
24
-
-
0037019339
-
RNA interference in adult mice
-
A.P. McCaffrey, L. Meuse.L, T.T. Pham, D.S. Conklin, G.H. Hannon, and M.A. Kay, RNA interference in adult mice, Nature, 2002, 418: 38-39.
-
(2002)
Nature
, vol.418
, pp. 38-39
-
-
McCaffrey, A.P.1
Meuse, L.2
Pham, T.T.3
Conklin, D.S.4
Hannon, G.H.5
Kay, M.A.6
-
25
-
-
0036787671
-
SiRNA-mediated gene silencing in vitro and in vivo
-
H. Xia, Q, Mao, H.L. Paulson, and B.L. Davidson, siRNA-mediated gene silencing in vitro and in vivo, Nat. Biotechnol., 2002, 20: 1006-1010.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1006-1010
-
-
Xia, H.1
Mao, Q.2
Paulson, H.L.3
Davidson, B.L.4
-
26
-
-
0346888665
-
A statistical sampling algorithm for RNA secondary structure prediction
-
Y. Ding, and C.E. Lawrence, A statistical sampling algorithm for RNA secondary structure prediction, Nucleic Acids Res., 2003, 31: 7280-7301
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 7280-7301
-
-
Ding, Y.1
Lawrence, C.E.2
-
27
-
-
4544332803
-
Rational design of siRNA with Sfold software
-
ed. Krishnarao Appasani, Cambridge University Press (PDF available from Sfold Web site)
-
Y. Ding, and C.E. Lawrence, Rational design of siRNA with Sfold software. In RNA Interference: from Basic Science to Drug Development, ed. Krishnarao Appasani, Cambridge University Press (PDF available from Sfold Web site), 2004.
-
(2004)
RNA Interference: From Basic Science to Drug Development
-
-
Ding, Y.1
Lawrence, C.E.2
-
28
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
S.M. Elbashir, J. Harborth, K. Weber, and T. Tuschl, Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods, 2002, 26: 199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
29
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
D.S. Schwarz, G. Hutvagner, T. Du, Z. Xu, N. Aronin, P.D. Zamore, Asymmetry in the assembly of the RNAi enzyme complex. Cell, 2003, 17:199-208.
-
(2003)
Cell
, vol.17
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
30
-
-
0344012459
-
Thermodynamic criteria for high hit rate antisense oligonucleotide design
-
O.V. Matveeva, D.H. Mathews, A.D. Tsodikov, S.A. Shabalina, R.F. Gesteland, J.F. Atkins, and S.M. Freier, Thermodynamic criteria for high hit rate antisense oligonucleotide design. Nucleic Acids Res., 2003, 31: 4989-4994.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 4989-4994
-
-
Matveeva, O.V.1
Mathews, D.H.2
Tsodikov, A.D.3
Shabalina, S.A.4
Gesteland, R.F.5
Atkins, J.F.6
Freier, S.M.7
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