Retinoic acid signaling in the nervous system of adult vertebrates

Neuroscientist

Volumn 10, Issue 5, 2004, Pages 409-421

  Mey, Jörg ^a   McCaffery, Peter ^b,c  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Depression; Learning; Parkinson's disease; Plasticity; Regeneration; Retinoic acid

Indexed keywords

CYTOKINE; RETINOIC ACID;

BEHAVIOR; BIRD; CELL DIFFERENTIATION; COGNITION; CORPUS STRIATUM; DEPRESSION; FOREBRAIN; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLIA CELL; HIPPOCAMPUS; HUNTINGTON CHOREA; LEARNING; LONG TERM MEMORY; LONG TERM POTENTIATION; MENTAL DISEASE; MOTOR NEURON DISEASE; NERVE CELL; NERVE CELL PLASTICITY; NERVE FIBER REGENERATION; NERVE INJURY; NERVE REGENERATION; NERVOUS SYSTEM; NERVOUS SYSTEM DEVELOPMENT; NEUROBIOLOGY; NONHUMAN; PARKINSON DISEASE; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REVIEW; SCHIZOPHRENIA; SCIATIC NERVE; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD INJURY; TASK PERFORMANCE; TRAINING; VERTEBRATE; ZEBRA FISH;

ANIMALS; LEARNING; NERVE REGENERATION; NERVOUS SYSTEM; NEURONAL PLASTICITY; SIGNAL TRANSDUCTION; TRETINOIN;

EID: 4544263420     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/1073858404263520     Document Type: Review

References (107)

1. Abu-Abed S, Dollé P, Metzger D, Beckett B, Chambon P, Petkovich M. 2001. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes Dev 15:226-40.
2. Abu-Abed S, MacLean G, Fraulob V, Chambon P, Petkovich M, Dollé P. 2002. Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis. Mech Dev 110:173-7.
3. Alfos S, Boucheron C, Pallet V, Higueret D, Enderlin V, Béracochéa D, and others. 2001. A retinoic acid receptor antagonist suppresses brain retinoic acid receptor overexpression and reverses a working memory deficit induced by chronic ethanol consumption in mice. Alcohol Clin Exp Res 25:1506-14.
4. Alvarez-Buylla A, Kirn JR. 1997. Birth, migration, incorporation, and death of vocal control neurons in adult songbirds. J Neurobiol 33:585-601.
5. Andrews PW, Nudelman E, Hakomori S, Fenderson BA. 1990. Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid, hexamethylene bisacetamide (HMBA) or bromodeoxyuridine (BUdR). Differentiation 43:131-8.
6. Bain G, Kitchens D, Yao M, Huettner JE, Gottlieb DI. 1995. Embryonic stem cells express neuronal properties in vitro. Dev Biol 168:342-57.
7. Bouillet P, Oulad-Abdelghani M, Vicaire S, Garnier J-M, Schuhbaur B, Dolfi P, and others. 1995. Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Epg12). Dev Biol 170:420-33.
8. Boylan JF, Gudas L. 1992. The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 teratocarcinoma stem cells. J Biol Chem 267:21486-91.
9. Brewer C. 1993. Recent developments in disulfiram treatment. Alcohol 28:383-95.
10. Budhu AS, Noy N. 2002. Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest. Mol Cell Biol 22:2632-41.
11. Cameron HA, Tanapat P, Gould E. 1998. Adrenal steroids and N-methyl-D-aspartate receptor activation regulate neurogenesis in the dentate gyrus of adult rats through a common pathway. Neuroscience 82:349-54.
12. Chambon P. 1996. A decade of molecular biology of retinoic acid receptors. FASEBJ 10:940-54.
13. Chandrasekaran V, Zhai Y, Wagner M, Kaplan PL, Napoli JL, Higgins D. 2000. Retinoic acid regulates the morphological development of sympathetic neurons. J Neurobiol 42:383-93.
14. Chen Y, Sharma RP, Costa RH, Grayson DR. 2002. On the epigenetic regulation of the human reelin promoter. Nucleic Acids Res 30:2930-9.
15. Cheung WM, Chu AH, Ip NY. 2000. Identification of candidate genes induced by retinoic acid in embryonal carcinoma cells. J Neurochem 68:1882-8.
16. Cheung WMW, Ip NY. 2000. Interaction of neurotrophins and retinoic acid in neural differentiation. Mol Cells 8:496-502.
17. Chiang M-Y, Misner D, Kempermann G, Schikorski T, Giguère V, Sucov HM, and others. 1998. An essential role for retinoid receptors RARβ and RXRγ in long-term potentiation and depression. Neuron 21:1353-61.
18. Cocco S, Diaz G, Stancampiano R, Diana A, Carta M, Curreli R, and others. 2002. Vitamin A deficiency produces spatial learning and memory impairment in rats. Neuroscience 115:475-82.
19. Corcoran J, Maden M. 1999. Nerve growth factor acts via retinoic acid synthesis to stimulate neurite outgrowth. Nat Neurosci 2:307-8.
20. Corcoran J, Shroot B, Pizzey J, Maden M. 2000. The role of retinoic acid receptors in neurite outgrowth from different populations of embryonic mouse dorsal root ganglia. J Cell Sci 113:2567-74.
21. Corcoran J, So PL, Barber RD, Vincent KJ, Mazarakis ND, Mitrophanous KA, and others. 2002. Retinoic acid receptor beta2 and neurite outgrowth in the adult mouse spinal cord in vitro. J Cell Sci 115:3779-86.
22. Corcoran J, So PL, Maden M. 2002. Absence of retinoids can induces motoneuron disease in the adult rat and a retinoid defect is present in motoneuron disease patients. J Cell Sci 115:4735-41.
23. Crandall J, Sakai Y, Zhang J, Koul O, Mineur Y, Crusio WE, and others. 2004. 13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependant learning in mice. Proc Natl Acad Sci USA 100:5111-16.
24. Delva L, Bastie J-N, Rochette-Egly C, Kraiba R, Balitrand G, Despouy G, and others. 1999. Physical and functional interactions between cellular retinoic acid binding proteins II and the retinoic acid-dependent nuclear complex. Mol Cell Biol 19:7158-67.
25. Denisenko-Nehrbass NI, Jarvis E, Scharff C, Nottebohm F, Mello CV. 2000. Site-specific retinoic acid production in the brain of adult songbirds. Neuron 27:359-70.
26. Denisenko-Nehrbass NI, Mello CV. 2001. Molecular targets of disulfiram action on song maturation in zebra finches. Mol Brain Res 87:246-50.
27. DiProspero NA, Meiners S, Geller HM. 1997. Inflammatory cytokines interact to modulate extracellular matrix and astrocytic support of neurite outgrowth. Exp Neurol 148:628-39.
28. Duester G. 2003. Alcohol dehydrogenase as a critical mediator of retinoic acid synthesis from vitamin A in the mouse embryo. J Nutr 128:459S-62S.
29. Eichele G. 1997. Retinoids: from hindbrain patterning to Parkinson disease. Trends Genet 13:343-5.
30. Etchamendy N, Enderlin V, Marighetto A, Pallet V, Higueret P, Jaffard R. 2003. Vitamin A deficiency and relational memory deficit in adult mice: relationships with changes in brain retinoid signalling. Behav Brain Res 145:37-49.
31. Etchamendy N, Enderlin V, Marighetto A, Vouimba R-M, Pallet V, Jaffard R, and others. 2002. Alleviation of a selective age-related relational memory deficit in mice by pharmacologically induced normalization of brain retinoid signaling. J Neurosci 21:6423-9.
32. Fisher CM. 1998. 'Catalonia' due to disulfiram toxicity. Arch Neurol 46:789-804.
33. Ghyselinck NB, Bavik C, Sapin V, Mark M, Bonnier D, Hindelang C, and others. 1999. Cellular retinol-binding protein I is essential for vitamin A homeostasis. EMBO J 18:4903-14.
34. Gillen C, Korfhage C, Müller HW. 1997. Gene expression in nerve regeneration. Neuroscientist 3:112-22.
35. Goodman AB. 1998. Three independent lines of evidence suggest retinoids as causal to schizophrenia. Proc Natl Acad Sci USA 95:7240-44.
36. Gottesman ME, Quadra L, Blaner WS. 2001. Studies of vitamin A metabolism in mouse model systems. Bioessays 23:419.
37. Grondona JM, Kastner P, Gansmuller A, Décimo D, Chambon P. 1996. Retinal dysplasia and degeneration in RARbeta2/RARgamma2 compound mutant mice. Development 122:2173-88.
38. Gudas LJ, Sporn MB, Roberts AB. 1994. Cellular biology and biochemistry of the retinoids. In: Sporn MB, Roberts AB, Goodman DS, editors. The retinoids: biology, chemistry, and medicine. New York: Raven.
39. Haskell BE, Stach RW, Werrbach-Perez K, Perez-Polo JR. 1987. Effect of retinoic acid on nerve growth factor receptors. Cell Tissue Res 247:67-73.
40. Hazen PG, Carney JF, Walker AE, Stewart JJ. 1983. Depression: a side effect of 13-cis-retinoic acid therapy. J Am Acad Dermatol 9:278-9.
41. Henion PS, Weston JA. 1994. Retinoic acid selectively promotes the survival and proliferation of neurogenic precursors in cultured neural crest cell populations. Dev Biol 161:243-50.
42. Hill DP, Robertson KA. 1998. Differentiation of LA-N-5 neuroblastoma cells into cholinergic neurons: methods for differentiation, immunohistochemistry and reporter gene introduction. Brain Res Brain Res Protoc 2:183-90.
43. Hoist AV, Lefcort F, Rohrer H. 1997. TrkA expression levels of sympathetic neurons correlate with NGF-dependent survival during development and after treatment with retinoic acid. Eur J Neurosci 9:2169-77.
44. Hoist Av, Rodriguez-Tébar A, Michaille J-J, Dhouailly D, Bäckström A, Ebendal T, and others. 1995. Retinoic acid-mediated increase in TrkA expression is sufficient to elicit NGF-dependent survival of sympathetic neurons. Mol Cell Neurosci 6:185-98.
45. Hull PR, D'Arcy C. 2003. Isotretinoin use and subsequent depression and suicide: presenting the evidence. Am J Clin Dermatol 4:493-505.
46. Hunter K, Maden M, Summerbell D, Eriksson U, Holder N. 1991. Retinoic acid stimulates neurite outgrowth in the amphibian spinal cord. Proc Natl Acad Sci U S A 88:3666-70.
47. Hwa V, Oh Y, Rosenfeld RG. 1997. Insulin-like growth factor binding protein-3 and -5 are regulated by transforming growth factor-beta and retinoid acid in the human prostate adenocarcinoma cell line PC-3. Endocrine 6:235-42.
48. Impagnatiello F, Guidotti AR, Pesold C, Dwivedi Y, Caruncho H, Pisu MG, and others. 1998. A decrease of reelin expression as a putative vulnerability factor in schizophrenia. Proc Natl Acad Sci USA 95:1571823.
49. Ingraham CA, Maness PF. 1990. Tyrosine phosphorylated proteins decrease during differentiation of neuronal and glial cells. Dev Neurosci 12:273-85.
50. Jick SS, Kremers HM, Vasilakis-Scaramozza C. 2003. Isotretinoin use and risk of depression, psychotic symptoms, suicide, and attempted suicide. Arch Dermatol 136:1231-6.
51. Johann V. Jeliaznik N, Schrage K, Mey J. 2003. Retinoic acid down-regulates the expression of ciliary neurotrophic factor (CNTF) in rat Schwann cells. Neurosci Lett 339:13-6.
52. Jonk LJ, de Jonge ME, Vervaart JM, Wissink S, Kruijer W. 1994. Isolation and developmental expression of retinoic-acid-induced genes. Dev Biol 161:604-14.
53. Kobayashi M, Fujii M, Kurihara K, Matsuoka I. 1998. Bone morphogenetic protein-2 and retinoic acid induce neurotrophin-3 responsiveness in developing rat sympathetic neurons. Mol Brain Res 53:206-17.
54. Krezel W, Ghyselinck NB, Samad TA, Dupé V, Kastner P, Borelli E, and others. 1998. Impaired locomotion and dopamine signaling in retinoid receptor mutant mice. Science 279:864-7.
55. Krezel W, Kastner P, Chambon P. 1999. Differential expression of retinoid receptors in the adult mouse central nervous system. Neuroscience 89:1291-300.
56. LaMantia AS. 1999. Forebrain induction, retinoic acid, and vulnerability to schizophrenia: insights from molecular and generic analysis in developing mice. Biol Psychiat 46:19-30.
57. Lamberg L. 1998. Acne drug depression warnings highlight need for expert care. JAMA 279:1057.
58. Laplane D, Altal N, Sauron B, de Billy A, Dubois B. 1992. Lesions of basal ganglia due to disulfiram neurotoxicity. J Neurol Neurosurg Psychiatry 55:925-9.
59. Leypoldt F, Lewerenz J, Methner A. 2001. Identification of genes upregulated by retinoic-acid-induced differentiation of the human neuronal precursor cell line NTERA-2 cl.Dl. J Neurochem 76:806-14.
60. Luthi-Carter R, Strand A, Peters NL, Solano SM, Hollingsworth ZR, Menon AS, and others. 2000. Decreased expression of striatal signaling genes in a mouse model of Huntington's disease. Hum Mol Genet 9:1259-71.
61. Maden M. 2003. Role and distribution of retinoic acid during CNS development. Int Rev Cytol 209:1-77.
62. Maden M, Keen G, Jones G. 1998. Retinoic acid as a chemotactic molecule in neuronal development. Int J Dev Neurosci 16:317-22.
63. Malberg JE, Eisch AJ, Nestler EJ, Duman RS. 2000. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20:9104-10.
64. Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schütz G, Umesono K, and others. 1995. The nuclear receptor superfamily: the second decade. Cell 83:835-9.
65. Matsuoka I, Mizuno N, Kurihara K. 1989. Cholinergic differentiation of clonal rat pheochromocytoma cells (PC12) induced by retinoic acid: increase of choline acetyltransferase activity and decrease of tyrosine hydroxylase activity. Brain Res 502:53-60.
66. McBurney MW. 1993. P19 embryonal carcinoma cells. Int J Dev Biol 37:135-40.
67. McCaffery P, Andreola F, Giandomenico V, De Luca LM. 2001. Vitamin A and gene expression. In: Moustaid Moussa N, Berdanier C, editors. Nutrient-gene interaction in health and disease. Boca Raton (FL): CRC Press, p 283-320.
68. McCaffery P, Dräger UC. 1994. High levels of retinoic acid-generating dehydrogenases in the meso-telencephalic dopamine system. Proc Natl Acad Sci U S A 91:7772-6.
69. McCaffery P, Dräger UC. 2000. Regulation of retinoic acid signaling in the embryonic nervous system: a master differentiation factor. Cytokine Growth Factor Rev 11:233-49.
70. McCaffery P, Lee M-O, Wagner MA, Sladek NE, Dräger UC. 1992. Asymmetrical retinoic acid synthesis in the dorsoventral axis of the retina. Development 115:371-82.
71. McCaffery P, Wagner E, O'Neil J, Petkovic M, Dräger UC. 1999. Dorsal and ventral retinal territories defined by retinoic acid synthesis, break-down and nuclear receptor expression. Mech Dev 82:119-30.
72. McEwen BS. 1999. Stress and hippocampal plasticity. Ann Rev Neurosci 22:105-22.
73. Medhora MM. 2000. Retinoic acid upregulates beta(1)-integrin in vascular smooth muscle cells and alters adhesion to fibronectin. Am J Physiol Heart Circ Physiol 279:382-7.
74. Mey J. 2001. Retinoic acid as a regulator of cytokine signaling after nerve injury. Z Naturforsch C 56c:163-76.
75. Mey J, McCaffery P, Dräger UC. 1997. Retinoid acid synthesis in the developing chick retina. J Neurosci 17:7441-9.
76. Mey J, Rombach N. 1999. Retinoic acid increases BDNF-dependent regeneration of chick retinal ganglion cells in vitro. Neuroreport 10:3573-7.
77. Misner DL, Jacobs S, Shimizu Y, de Urquiza AM, Solomin L, Perlmann T, and others. 2001. Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity. Proc Natl Acad Sci U S A 98:11714-9.
78. Napoli JL. 1993. Biosynthesis and metabolism of retinoic acid: roles of CRBP and CRABP in retinoic acid-roles of CRBP and CRABP in retinoic acid homeostasis. J Nutr 123:362-6.
79. Napoli JL. 1999. Retinoic acid: its biosynthesis and metabolism. Nucl Acid Res Mol Biol 63:139-88.
80. Niederreither K, Subbarayan V, Dollé P, Chambon P. 1999. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet 21:444-8.
81. Noll E, Miller RH. 1994. Regulation of oligodendrocyte differentiation: a role for retinoic acid in the spinal cord. Development 120:649-60.
82. Oulad-Abdelghani M, Chazaud C, Bouillet P, Mattel M-G, Dollé P, Chambon P. 1998. Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-β superfamily. Int J Dev Biol 42:23-32.
83. Quinn SDP, De Boni U. 1991. Enhanced neuronal regeneration by retinoic acid of murine dorsal root ganglia and of fetal murine and human spinal cord in vitro. In Vitro Cell Dev Biol 27A:55-62.
84. Raivich G, Bohatschek M, Kloss CUA, Werner A, Jones LL, Kreutzberg GW. 1999. Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res Rev 30:77-105.
85. Rodríguez-Tebar A, Rohrer H. 1991. Retinoic acid induces NGF-dependent survival response and high-affinity binding NGF receptors in immature chick sympathetic neurons. Development 112:813-20.
86. Ross S, Ahrens RA, De Luca LM. 1994. Retinoic acid enhances adhesivenes, laminin and integrin gamma1 synthesis and retinoic acid receptor expression in F9 teratocarcinoma cells. J Cell Physiol 159:263-73.
87. Saga Y, Kobayashi M, Ohta H, Murai N, Nakai N, Oshima M, and others. 1999. Impaired extrapyramidal function caused by the targeted disruption of retinoid X receptor RXRgamma1 isoform. Genes Cells 4:219-28.
88. Sakai Y, Meno C, Fujii H, Nishino J, Shiratori H, Saijoh Y, and others. 2001. The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo. Genes Dev 15:213-25.
89. Samad TA, Krezel W, Chambon P, Borelli E. 1997. Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family. Proc Natl Acad Sci U S A 94:14349-54.
90. Sheline YI. 2003. Neuroimaging studies of mood disorder effects on the brain. Biol Psychiat 54:338-52.
91. Sheline YI, Wang PW, Gado MH, Csernansky JG, Vamier MW. 1996. Hippocampal atrophy in recurrent major depression. Proc Natl Acad Sci U S A 93:3908-13.
92. Staines WA, Craig J, Reuhl K, McBurney MW. 1996. Retinoic acid treated P19 embryonal carcinoma cells differentiate into oligodendrocytes capable of myelination. Neuroscience 71:845-53.
93. Swindell EC, Thaller C, Sockanathan S, Petkovic M, Jessell TM, Eichele G. 1999. Complementary domains of retinoic acid production and degradation in the early chick embryo. Dev Biol 216:282-96.
94. Takahashi J, Palmer TD, Gage FH. 1999. Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures. J Neurobiol 38:65-81.
95. Thang SH, Kobayashi M, Matsuoka I. 2000. Regulation of glial cell line-derived neurotrophic factor responsiveness in developing rat sympathetic neurons by retinoic acid and bone morphogenetic protein-2. J Neurosci 20:2917-25.
96. Vogel G. 2000. Neuroscience: new brain cells prompt new theory of depression. Science 290:258-9.
97. Warkany L, Schraffenberger E. 1946. Congenital malformations induced in rats by maternal vitamin A deficiency: 1. Defects of the eye. Arch Ophthalmol 35:150-69.
98. Whitesides J, Hall M, Anchan R, LaMantia A-S. 1998. Retinoid signaling distinguishes a subpopulation of olfactory receptor neurons in the developing and adult mouse. J Comp Neurol 394:445-61.
99. Wilson JG, Roth CB, Warkany J. 1953. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency: effects of restoration of vitamin A at various times during gestation. Am J Anat 92:189-217.
100. Wuarin L, Sidell N. 1991. Differential susceptibilities of spinal cord neurons to retinoic acid-induced survival and differentiation. Dev Biol 144:429-35.
101. Wuarin L, Sidell N, De Vellis J. 1990. Retinoids increase perinatal spinal cord neuronal survival and astroglial differentiation. Int J Dev Neurosci 8:317-26.
102. Wyatt S, Andres R, Rohrer H, Davies AM. 1999. Regulation of neurotrophin receptor expression by retinoic acid in mouse sympathetic neuroblasts. J Neurosci 19:1062-71.
103. Yamagata T, Momoi MY, Yanagisawa M, Kumagai H, Yamakado M, Momoi T. 1994. Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Dev Brain Res 77:163-76.
104. Yamamoto M, McCaffery P, Dräger UC. 1996. Influence of the choroid plexus on cerebellar development: analysis of retinoic acid synthesis. Dev Brain Res 93:182-90.
105. Zetterström RH, Lindquist E, Mata de Urquiza A, Tomac A, Eriksson U, Perlmann T, and others. 1999. Role of retinoids in the CNS: differential expression of retinoid binding proteins and receptors and evidence for presence of retinoic acid. Eur J Neurosci 11:407-16.
106. Zetterström RH, Simon A, Giacobini MM, Eriksson U, Olson L. 1994. Localization of cellular retinoid-binding proteins suggests specific roles for retinoids in the adult central nervous system. Neuroscience 62:899-918.
107. Zhelyaznik N, Schrage K, McCaffery P, Mey J. 2003. Activation of retinoic acid signaling after sciatic nerve injury: upregulation of cellular retinoid binding proteins. Eur J Neurosci 18:1033-40.