Effects of intercellular adhesion molecule 1 (ICAM-1) null mutation on radiation-induced pulmonary fibrosis and respiratory insufficiency in mice

Journal of the National Cancer Institute

Volumn 94, Issue 10, 2002, Pages 733-741

  Hallahan, Dennis E ^a,b   Geng, Ling ^a   Shyr, Yu ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; COLLAGEN TYPE 3; HYDROXYPROLINE; INTERCELLULAR ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RADIOTHERAPY; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; GENE MUTATION; HOMOZYGOSITY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; LUNG ALVEOLUS WALL; LUNG CANCER; LUNG COMPLIANCE; LUNG FIBROSIS; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIATION DOSE; RADIATION INJURY; RESPIRATORY FAILURE; WILD TYPE;

EID: 0037094284     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/94.10.733     Document Type: Article

References (29)

1. The expression of early and late damage after thoracic irradiation: A comparison between CBA and C57B1 mice
2. Evidence for two patterns of inheritance of sensitivity to induction of lung fibrosis in mice by radiation, one of which involves two genes
3. The genetic basis of strain-dependent differences in the early phase of radiation injury in mouse lung
4. Radiation-induced pulmonary endothelial dysfunction and hydroxyproline accumulation in four strains of mice
5. The sequence of histological changes in mouse lungs after single doses of x-rays
6. Specific early fine structural changes in the lung following irradiation
7. Microvasculature and radiation damage
8. Lung effects after TBI of mice and bone marrow transplant patients: Comparison of experimental and clinical data
9. The pulmonary response to sublethal thoracic irradiation in the rat
10. The sequence of histological changes in mouse lungs after single doses of x-rays
11. Pharmacological alteration of the lung vascular response to radiation
12. Immunohistochemical localization of TGF-B and TNF in the lungs after irradiation
13. E-selectin gene induction by ionizing radiation is independent of cytokine induction
14. Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium
15. Mimetics attenuate E-selectin-mediated leukocyte adhesion to irradiated human endothelial cells
16. ICAM-1 null mutation abrogates the inflammatory response to ionizing radiation
17. Ionizing radiation mediates expression of cell adhesion molecules in distinct histological patterns within the lung
18. CTLA41g inhibits airway eosinophilia and hyperresponsiveness by regulating the development of Th1/Th2 subsets in a murine model of asthma
19. Structural and functional abnormalities of the airways of hyperoxia-exposed immature rats
20. Fibroblast radiosensitivity in vitro and lung fibrosis in vivo: Comparison between a fibrosis-prone and fibrosis-resistant mouse strain
21. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid
22. Long-term morphologic and biochemical features of experimentally induced lung fibrosis in the mouse
23. The effects of steroids on radiation-induced lung disease in the rat
24. Radiation pneumonitis in mice. Some effects of corticosteroids on mortality and pulmonary physiology
25. Radiation pneumonitis and fibrosis in mouse lung assayed by respiratory frequency and histology
26. A plethysmographic method for measuring function in locally irradiated mouse lung
27. Intercellular adhesion molecule-1 deficiency prolongs survival and protects against the development of pulmonary inflammation during murine lupus
28. The role of P-selectin and ICAM-1 in acute lung injury as determined using blocking antibodies and mutant mice
29. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice