CDK9 a potential target for drug development

Medicinal Chemistry

Volumn 4, Issue 3, 2008, Pages 210-218

  Canduri, Fernanda ^a   Peres, Patrícia Cardoso ^b   Caceres, Rafael Andrade ^b   de Azevedo Jr , Walter Filgueira ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

CDK9; Drug design; Molecular modeling

Indexed keywords

6 O CYCLOHEXYLMETHYLGUANINE; 7 HYDROXYSTAUROSPORINE; CAN 508; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLIN DEPENDENT KINASE 9; CYCLIN DEPENDENT KINASE 9 INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; CYCLIN T1; FLAVOPIRIDOL; HYMENIALDISINE; INDIRUBIN; INDISULAM; N [5 (5 TERT BUTYL 2 OXAZOLYLMETHYLTHIO) 2 THIAZOLYL]ISONIPECOTAMIDE; OLOMOUCINE; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROTEIN P53; PROTEIN SERINE THREONINE KINASE INHIBITOR; PURVALANOL; RNA POLYMERASE II; ROSCOVITINE; STAUROSPORINE; TRANSACTIVATOR PROTEIN;

ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL; CANCER CELL CULTURE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME STRUCTURE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; NEUROBLASTOMA; NEUROECTODERM TUMOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TISSUE DIFFERENTIATION; TRANSCRIPTION REGULATION; TUMOR DIFFERENTIATION;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CLONING, MOLECULAR; CYCLIN-DEPENDENT KINASE 9; FLAVONES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PURINES; PYRAZOLES; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT;

EID: 45149133302     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340608784325205     Document Type: Article

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