메뉴 건너뛰기




Volumn 282, Issue 1, 2001, Pages 341-350

Polycystin-2 is a novel cation channel implicated in defective intracellular Ca2+ homeostasis in polycystic kidney disease

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CATION CHANNEL; CHAPERONE; INOSITOL TRISPHOSPHATE; POLYCYSTIN; PROTEASOME; RYANODINE;

EID: 0034810681     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4554     Document Type: Article
Times cited : (208)

References (43)
  • 1
    • 15844385078 scopus 로고    scopus 로고
    • PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein
    • (1996) Science , vol.272 , pp. 1339-1342
    • Mochizuki, T.1
  • 2
    • 0030588650 scopus 로고    scopus 로고
    • A gene similar to PKD1 maps to chromosome 4q22: A candidate gene for PKD2
    • (1996) Genomics , vol.38 , pp. 1-4
    • Schneider, M.C.1
  • 3
    • 12644290270 scopus 로고    scopus 로고
    • Identification and localization of polycystin, the PKD1 gene product
    • (1996) J. Clin. Invest , vol.98 , pp. 2674-2682
    • Geng, L.1
  • 4
    • 16944364699 scopus 로고    scopus 로고
    • Distribution and developmentally regulated expression of murine polycystin
    • (1997) Am. J. Physiol , vol.272 , pp. F451-F459
    • Geng, L.1
  • 5
    • 0029928062 scopus 로고    scopus 로고
    • Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1524-1528
    • Ward, C.J.1
  • 6
    • 0033021438 scopus 로고    scopus 로고
    • Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue
    • (1999) Am. J. Pathol , vol.154 , pp. 1721-1729
    • Ong, A.C.1
  • 8
    • 0030909957 scopus 로고    scopus 로고
    • PKD1 interacts with PKD2 through a probable coiled-coil domain
    • (1997) Nat. Genet , vol.16 , pp. 179-183
    • Qian, F.1
  • 10
    • 0031252295 scopus 로고    scopus 로고
    • Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation
    • (1997) Nat. Genet , vol.17 , pp. 179-181
    • Lu, W.1
  • 11
    • 0032540226 scopus 로고    scopus 로고
    • Somatic inactivation of Pkd2 results in polycystic kidney disease
    • (1998) Cell , vol.93 , pp. 177-188
    • Wu, G.1
  • 12
    • 0033989173 scopus 로고    scopus 로고
    • Cardiac defects and renal failure in mice with targeted mutations in Pkd2
    • (2000) Nat. Genet , vol.24 , pp. 75-78
    • Wu, G.1
  • 13
    • 0033214702 scopus 로고    scopus 로고
    • Identification and characterization of polycystin-2, the PKD2 gene product
    • (1999) J. Biol. Chem , vol.274 , pp. 28557-28565
    • Cai, Y.1
  • 14
    • 0028030252 scopus 로고
    • Single-channel inositol 1, 4, 5-trisphosphate receptor currents revealed by patch clamp of isolated Xenopus oocyte nuclei
    • (1994) J. Biol. Chem , vol.269 , pp. 29375-29378
    • Mak, D.O.1    Foskett, J.K.2
  • 16
    • 0028858161 scopus 로고
    • Multiple proteolytic systems, including the proteasome, contribute to CFTR processing
    • (1995) Cell , vol.83 , pp. 129-135
    • Jensen, T.J.1
  • 20
    • 0026781952 scopus 로고
    • Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
    • (1992) Nature , vol.358 , pp. 761-764
    • Denning, G.M.1
  • 21
    • 0028229572 scopus 로고
    • Characterization of the potassium channel from frog skeletal muscle sarcoplasmic reticulum membrane
    • (1994) J. Physiol , vol.477 , pp. 279-290
    • Wang, J.1    Best, P.M.2
  • 23
    • 0033598347 scopus 로고    scopus 로고
    • Polycystin-L is a calcium-regulated cation channel permeable to calcium ions
    • (1999) Nature , vol.401 , pp. 383-386
    • Chen, X.Z.1
  • 24
    • 0033399409 scopus 로고    scopus 로고
    • The rat pkd2 protein assumes distinct subcellular distributions in different organs
    • (1999) Am. J. Physiol , vol.277 , pp. F914-F925
    • Obermuller, N.1
  • 25
    • 0026033046 scopus 로고
    • Structural and functional characterization of inositol 1, 4, 5-trisphosphate receptor channel from mouse cerebellum
    • (1991) J. Biol. Chem , vol.266 , pp. 1109-1116
    • Maeda, N.1
  • 26
    • 0027946230 scopus 로고
    • Inositol (1, 4, 5)-trisphosphate (InsP3)-gated Ca channels from cerebellum: Conduction properties for divalent cations and regulation by intraluminal calcium
    • (1994) J. Gen. Physiol , vol.104 , pp. 821-856
    • Bezprozvanny, I.1    Ehrlich, B.E.2
  • 32
    • 0030794278 scopus 로고    scopus 로고
    • Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen
    • (1997) Mol. Cell Biol , vol.17 , pp. 4979-4990
    • Stubdal, H.1
  • 34
    • 0027946089 scopus 로고
    • Liddle’s syndrome: Heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel
    • (1994) Cell , vol.79 , pp. 407-414
    • Shimkets, R.A.1
  • 36
    • 0027232194 scopus 로고
    • Polycystic kidney disease: Primary extracellular matrix abnormality or defective cellular differentiation?
    • (1993) Kidney Int , vol.43 , pp. 101-108
    • Calvet, J.P.1
  • 37
    • 0029035757 scopus 로고
    • Apoptosis and loss of renal tissue in polycystic kidney diseases
    • (1995) N. Engl. J. Med , vol.333 , pp. 18-25
    • Woo, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.