Fibronectin expression modulates mammary epithelial cell proliferation during acinar differentiation

Cancer Research

Volumn 68, Issue 9, 2008, Pages 3185-3192

  Williams, Courtney M ^a   Engler, Adam J ^a   Slone, R Daniel ^a   Galante, Leontine L ^a   Schwarzbauer, Jean E ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN;

ACINAR CELL; ARTICLE; BREAST EPITHELIUM; CARCINOGENESIS; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DOWN REGULATION; GROWTH DISORDER; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; BIOLOGICAL MODEL; CELL CULTURE; CELL SIZE; CELL TRANSFORMATION; CYTOLOGY; GENETICS; MAMMARY GLAND; METABOLISM; MORPHOGENESIS; MULTICELLULAR SPHEROID; PHYSIOLOGY; ULTRASTRUCTURE;

CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SIZE; CELL TRANSFORMATION, NEOPLASTIC; DOWN-REGULATION; FIBRONECTINS; HUMANS; MAMMARY GLANDS, HUMAN; MODELS, BIOLOGICAL; MORPHOGENESIS; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 44849142138     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-2673     Document Type: Article

References (42)

1. Nelson CM, Bissell MJ. Of extracellular matrix, scaffolds, and signaling: Tissue architecture regulates development, homeostasis, and cancer. Annu Rev Cell Dev Biol 2006;22:287-309.
2. Stoker AW, Hatier C, Bissell MJ. The embryonic environment strongly attenuates v-src oncogenesis in mesenchymal and epithelial tissues, but not in endothelia. J Cell Biol 1990;111:217-28.
3. van Roozendaal KE, Klijn JG, van Ooijen B, et al. Differential regulation of breast tumor cell proliferation by stromal fibroblasts of various breast tissue sources. Int J Cancer 1996;65:120-5.
4. Deng G, Lu Y, Zlotnikov G, Thor AD, Smith HS. Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science 1996;274:2057-9.
5. Forsti A, Louhelainen J, Soderberg M, Wijkstrom H, Hemminki K. Loss of heterozygosity in tumour-adjacent normal tissue of breast and bladder cancer. Eur J Cancer 2001;37:1372-80.
6. Engbring JA, Kleinman HK. The basement membrane matrix in malignancy. J Pathol 2003;200:465-70.
7. Aszodi A, Legate KR, Nakchbandi I, Fassler R. What mouse mutants teach us about extracellular matrix function. Annu Rev Cell Dev Biol 2006;22:591-621.
8. Woodward TL, Mienaltowski AS, Modi RR, Bennett JM, Haslam SZ. Fibronectin and the α(5)β(1) integrin are under developmental and ovarian steroid regulation in the normal mouse mammary gland. Endocrinology 2001;142:3214-22.
9. Ronnov-Jessen L, Petersen OW, Bissell MJ. Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiol Rev 1996;76:69-125.
10. Sakakura T. New aspects of stroma-parenchyma relations in mammary gland differentiation. Int Rev Cytol 1991;125:165-202.
11. Kadar A, Tokes AM, Kulka J, Robert L. Extracellular matrix components in breast carcinomas. Semin Cancer Biol 2002;12:243-57.
12. Vasaturo F, Sallusti E, Gradilone A, et al. Comparison of extracellular matrix and apoptotic markers between benign lesions and carcinomas in human breast. Int J Oncol 2005;27:1005-11.
13. Christensen L. The distribution of fibronectin, laminin and tetranectin in human breast cancer with special attention to the extracellular matrix. APMIS Suppl 1992;26:1-39.
14. Koukoulis GK, Howeedy AA, Korhonen M, Virtanen I, Gould VE. Distribution of tenascin, cellular fibronectins and integrins in the normal, hyperplastic and neoplastic breast. J Submicrosc Cytol Pathol 1993;25:285-95.
15. Paszek MJ, Weaver VM. The tension mounts: mechanics meets morphogenesis and malignancy. J Mammary Gland Biol Neoplasia 2004;9:325-42.
16. Boyd NF, Jensen HM, Cooke G, Han HL. Relationship between mammographic and histological risk factors for breast cancer. J Natl Cancer Inst 1992;84:1170-9.
17. Paszek MJ, Zahir N, Johnson KR, et al. Tensional homeostasis and the malignant phenotype. Cancer Cell 2005;8:241-54.
18. Hao X, Sun B, Hu L, et al. Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis. Cancer 2004;100:1110-22.
19. Yao ES, Zhang H, Chen YY, et al. Increased β1 integrin is associated with decreased survival in invasive breast cancer. Cancer Res 2007;67:659-64.
20. Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003;30:256-68.
21. Howlett AR, Bailey N, Damsky C, Petersen OW, Bissell MJ. Cellular growth and survival are mediated by β1 integrins in normal human breast epithelium but not in breast carcinoma. J Cell Sci 1995;108:1945-57.
22. Muthuswamy SK, Li D, Lelievre S, Bissell MJ, Brugge JS. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nat Cell Biol 2001;3:785-92.
23. Debnath J, Walker SJ, Brugge JS. Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner. J Cell Biol 2003;163:315-26.
24. Gudjonsson T, Ronnov-Jessen L, Villadsen R, Rank F, Bissell MJ, Petersen OW. Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. J Cell Sci 2002;115:39-50.
25. Park CC, Zhang H, Pallavicini M, et al. β1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res 2006;66:1526-35.
26. Engvall E, Ruoslahti E. Binding of soluble form of fibroblast surface protein, fibronectin, to collagen. Int J Cancer 1977;20:1-5.
27. Mao Y, Schwarzbauer JE. Stimulatory effects of a three-dimensional microenvironment on cell-mediated fibronectin fibrillogenesis. J Cell Sci 2005;118:4427-36.
28. Wierzbicka-Patynowski I, Mao Y, Schwarzbauer JE. Continuous requirement for pp60-Src and phosphopaxillin during fibronectin matrix assembly by transformed cells. J Cell Physiol 2007;210:750-6.
29. Engler AJ, Griffin MA, Sen S, Bonnemann CG, Sweeney HL, Discher DE. Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J Cell Biol 2004;166:877-87.
30. Pelham RJ, Jr., Wang Y. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci U S A 1997;94:13661-5.
31. Galante LL, Schwarzbauer JE. Requirements for sulfate transport and the diastrophic dysplasia sulfate transporter in fibronectin matrix assembly. J Cell Biol 2007;179:999-1009.
32. Vandesompele J, De Preter K, Pattyn F, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002;3:1-12.
33. Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell 2002;111:29-40.
34. Weaver VM, Petersen OW, Wang F, et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 1997;137:231-45.
35. Boudreau N, Werb Z, Bissell MJ. Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proc Natl Acad Sci U S A 1996;93:3509-13.
36. Zicha D, Genot E, Dunn GA, Kramer IM. TGFβ1 induces a cell-cycle-dependent increase in motility of epithelial cells. J Cell Sci 1999;112:447-54.
37. Faraldo MM, Deugnier MA, Lukashev M, Thiery JP, Glukhova MA. Perturbation of β1-integrin function alters the development of murine mammary gland. EMBO J 1998;17:2139-47.
38. Haslam SZ, Woodward TL. Reciprocal regulation of extracellular matrix proteins and ovarian steroid activity in the mammary gland. Breast Cancer Res 2001;3:365-72.
39. Sakai T, Larsen M, Yamada KM. Fibronectin requirement in branching morphogenesis. Nature 2003;423:876-81.
40. Roman J, McDonald JA. Expression of fibronectin, the integrin α5, and α-smooth muscle actin in heart and lung development. Am J Respir Cell Mol Biol 1992;6:472-80.
41. Alowami S, Troup S, Al-Haddad S, Kirkpatrick I, Watson PH. Mammographic density is related to stroma and stromal proteoglycan expression. Breast Cancer Res 2003;5:R129-35.
42. Walker RA. The complexities of breast cancer desmoplasia. Breast Cancer Res 2001;3:143-5.