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Volumn 319, Issue 1, 2008, Pages 10-22

Zebrafish blowout provides genetic evidence for Patched1-mediated negative regulation of Hedgehog signaling within the proximal optic vesicle of the vertebrate eye

Author keywords

Coloboma; Hedgehog; Optic vesicle; Patched1; Zebrafish

Indexed keywords

CYCLOPAMINE; PROTEIN PATCHED 1; PROTEIN PATCHED 2; SONIC HEDGEHOG PROTEIN;

EID: 44749090636     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2008.03.035     Document Type: Article
Times cited : (48)

References (74)
  • 1
    • 34247101182 scopus 로고    scopus 로고
    • Molecular mechanisms of optic vesicle development: complexities, ambiguities and controversies
    • Adler R., and Canto-Soler M.V. Molecular mechanisms of optic vesicle development: complexities, ambiguities and controversies. Dev. Biol. 305 (2007) 1-13
    • (2007) Dev. Biol. , vol.305 , pp. 1-13
    • Adler, R.1    Canto-Soler, M.V.2
  • 2
    • 33644509505 scopus 로고    scopus 로고
    • Patched1 functions as a gatekeeper by promoting cell cycle progression
    • Adolphe C., Hetherington R., Ellis T., and Wainwright B. Patched1 functions as a gatekeeper by promoting cell cycle progression. Cancer Res. 66 (2006) 2081-2088
    • (2006) Cancer Res. , vol.66 , pp. 2081-2088
    • Adolphe, C.1    Hetherington, R.2    Ellis, T.3    Wainwright, B.4
  • 3
    • 33846902382 scopus 로고    scopus 로고
    • A general role of hedgehog in the regulation of proliferation
    • Agathocleous M., Locker M., Harris W.A., and Perron M. A general role of hedgehog in the regulation of proliferation. Cell Cycle 6 (2007) 156-159
    • (2007) Cell Cycle , vol.6 , pp. 156-159
    • Agathocleous, M.1    Locker, M.2    Harris, W.A.3    Perron, M.4
  • 4
    • 2442482418 scopus 로고    scopus 로고
    • Hedgehog signaling in vertebrate eye development: a growing puzzle
    • Amato M.A., Boy S., and Perron M. Hedgehog signaling in vertebrate eye development: a growing puzzle. Cell Mol. Life Sci. 61 (2004) 899-910
    • (2004) Cell Mol. Life Sci. , vol.61 , pp. 899-910
    • Amato, M.A.1    Boy, S.2    Perron, M.3
  • 8
    • 0034081860 scopus 로고    scopus 로고
    • The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity
    • Barresi M.J., Stickney H.L., and Devoto S.H. The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity. Development 127 (2000) 2189-2199
    • (2000) Development , vol.127 , pp. 2189-2199
    • Barresi, M.J.1    Stickney, H.L.2    Devoto, S.H.3
  • 9
    • 0029075802 scopus 로고
    • Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain
    • Barth K.A., and Wilson S.W. Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. Development 121 (1995) 1755-1768
    • (1995) Development , vol.121 , pp. 1755-1768
    • Barth, K.A.1    Wilson, S.W.2
  • 11
    • 0033386714 scopus 로고    scopus 로고
    • The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain
    • Bertuzzi S., Hindges R., Mui S.H., O'Leary D.D., and Lemke G. The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Genes Dev. 13 (1999) 3092-3105
    • (1999) Genes Dev. , vol.13 , pp. 3092-3105
    • Bertuzzi, S.1    Hindges, R.2    Mui, S.H.3    O'Leary, D.D.4    Lemke, G.5
  • 14
    • 0030297553 scopus 로고    scopus 로고
    • Dual roles for patched in sequestering and transducing Hedgehog
    • Chen Y., and Struhl G. Dual roles for patched in sequestering and transducing Hedgehog. Cell 87 (1996) 553-563
    • (1996) Cell , vol.87 , pp. 553-563
    • Chen, Y.1    Struhl, G.2
  • 15
  • 16
  • 17
    • 0029791854 scopus 로고    scopus 로고
    • Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning
    • Concordet J.P., Lewis K.E., Moore J.W., Goodrich L.V., Johnson R.L., Scott M.P., and Ingham P.W. Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development 122 (1996) 2835-2846
    • (1996) Development , vol.122 , pp. 2835-2846
    • Concordet, J.P.1    Lewis, K.E.2    Moore, J.W.3    Goodrich, L.V.4    Johnson, R.L.5    Scott, M.P.6    Ingham, P.W.7
  • 18
    • 0032486433 scopus 로고    scopus 로고
    • Teratogen-mediated inhibition of target tissue response to Shh signaling
    • Cooper M.K., Porter J.A., Young K.E., and Beachy P.A. Teratogen-mediated inhibition of target tissue response to Shh signaling. Science 280 (1998) 1603-1607
    • (1998) Science , vol.280 , pp. 1603-1607
    • Cooper, M.K.1    Porter, J.A.2    Young, K.E.3    Beachy, P.A.4
  • 19
    • 0038444653 scopus 로고    scopus 로고
    • Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development
    • Dakubo G.D., Wang Y.P., Mazerolle C., Campsall K., McMahon A.P., and Wallace V.A. Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development 130 (2003) 2967-2980
    • (2003) Development , vol.130 , pp. 2967-2980
    • Dakubo, G.D.1    Wang, Y.P.2    Mazerolle, C.3    Campsall, K.4    McMahon, A.P.5    Wallace, V.A.6
  • 23
    • 32344435631 scopus 로고    scopus 로고
    • Secreted inducers in vertebrate eye development: more functions for old morphogens
    • Esteve P., and Bovolenta P. Secreted inducers in vertebrate eye development: more functions for old morphogens. Curr. Opin. Neurobiol. 16 (2006) 13-19
    • (2006) Curr. Opin. Neurobiol. , vol.16 , pp. 13-19
    • Esteve, P.1    Bovolenta, P.2
  • 25
    • 0037326951 scopus 로고    scopus 로고
    • The zebrafish as a tool for understanding the biology of visual disorders
    • Goldsmith P., and Harris W.A. The zebrafish as a tool for understanding the biology of visual disorders. Semin. Cell Dev. Biol. 14 (2003) 11-18
    • (2003) Semin. Cell Dev. Biol. , vol.14 , pp. 11-18
    • Goldsmith, P.1    Harris, W.A.2
  • 27
    • 15444372039 scopus 로고    scopus 로고
    • Tbx2b is essential for neuronal differentiation along the dorsal/ventral axis of the zebrafish retina
    • Gross J.M., and Dowling J.E. Tbx2b is essential for neuronal differentiation along the dorsal/ventral axis of the zebrafish retina. Proc. Natl Acad. Sci. USA 102 (2005) 4371-4376
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 4371-4376
    • Gross, J.M.1    Dowling, J.E.2
  • 28
    • 38949180529 scopus 로고    scopus 로고
    • Zebrafish mutants as models for congenital ocular disorders in humans
    • Gross J.M., and Perkins B.D. Zebrafish mutants as models for congenital ocular disorders in humans. Mol. Reprod. Dev. 75 (2008) 547-555
    • (2008) Mol. Reprod. Dev. , vol.75 , pp. 547-555
    • Gross, J.M.1    Perkins, B.D.2
  • 31
    • 0031827413 scopus 로고    scopus 로고
    • Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain
    • Hallonet M., Hollemann T., Wehr R., Jenkins N.A., Copeland N.G., Pieler T., and Gruss P. Vax1 is a novel homeobox-containing gene expressed in the developing anterior ventral forebrain. Development 125 (1998) 2599-2610
    • (1998) Development , vol.125 , pp. 2599-2610
    • Hallonet, M.1    Hollemann, T.2    Wehr, R.3    Jenkins, N.A.4    Copeland, N.G.5    Pieler, T.6    Gruss, P.7
  • 32
    • 0033386715 scopus 로고    scopus 로고
    • Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system
    • Hallonet M., Hollemann T., Pieler T., and Gruss P. Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system. Genes Dev. 13 (1999) 3106-3114
    • (1999) Genes Dev. , vol.13 , pp. 3106-3114
    • Hallonet, M.1    Hollemann, T.2    Pieler, T.3    Gruss, P.4
  • 33
    • 0033048579 scopus 로고    scopus 로고
    • Zebrafish aussicht mutant embryos exhibit widespread overexpression of ace (fgf8) and coincident defects in CNS development
    • Heisenberg C.P., Brennan C., and Wilson S.W. Zebrafish aussicht mutant embryos exhibit widespread overexpression of ace (fgf8) and coincident defects in CNS development. Development 126 (1999) 2129-2140
    • (1999) Development , vol.126 , pp. 2129-2140
    • Heisenberg, C.P.1    Brennan, C.2    Wilson, S.W.3
  • 35
    • 0025941910 scopus 로고
    • The prenatal development of the optic fissure in colobomatous microphthalmia
    • Hero I., Farjah M., and Scholtz C.L. The prenatal development of the optic fissure in colobomatous microphthalmia. Invest. Ophthalmol. Vis. Sci. 32 (1991) 2622-2635
    • (1991) Invest. Ophthalmol. Vis. Sci. , vol.32 , pp. 2622-2635
    • Hero, I.1    Farjah, M.2    Scholtz, C.L.3
  • 37
    • 0028350952 scopus 로고
    • Whole-mount in situ hybridizations on zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes
    • Jowett T., and Lettice L. Whole-mount in situ hybridizations on zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes. Trends Genet. 10 (1994) 73-74
    • (1994) Trends Genet. , vol.10 , pp. 73-74
    • Jowett, T.1    Lettice, L.2
  • 39
    • 0033558211 scopus 로고    scopus 로고
    • Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning
    • Karlstrom R.O., Talbot W.S., and Schier A.F. Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning. Genes Dev. 13 (1999) 388-393
    • (1999) Genes Dev. , vol.13 , pp. 388-393
    • Karlstrom, R.O.1    Talbot, W.S.2    Schier, A.F.3
  • 40
    • 34347232361 scopus 로고    scopus 로고
    • Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression
    • Kim T.H., Goodman J., Anderson K.V., and Niswander L. Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression. Dev. Cell 13 (2007) 87-102
    • (2007) Dev. Cell , vol.13 , pp. 87-102
    • Kim, T.H.1    Goodman, J.2    Anderson, K.V.3    Niswander, L.4
  • 41
    • 17144364930 scopus 로고    scopus 로고
    • Repression of cell-cell fusion by components of the C. elegans vacuolar ATPase complex
    • Kontani K., Moskowitz I.P., and Rothman J.H. Repression of cell-cell fusion by components of the C. elegans vacuolar ATPase complex. Dev. Cell 8 (2005) 787-794
    • (2005) Dev. Cell , vol.8 , pp. 787-794
    • Kontani, K.1    Moskowitz, I.P.2    Rothman, J.H.3
  • 43
    • 43149104980 scopus 로고    scopus 로고
    • Genetic analysis of two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway
    • Koudijs M.J., den Broeder M.J., Groot E., and van Eeden F.J. Genetic analysis of two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway. BMC Dev. Biol. 8 (2008) 15
    • (2008) BMC Dev. Biol. , vol.8 , pp. 15
    • Koudijs, M.J.1    den Broeder, M.J.2    Groot, E.3    van Eeden, F.J.4
  • 44
    • 34347235154 scopus 로고    scopus 로고
    • Laminin {beta}1 and {gamma}1 containing laminins are essential for basement membrane integrity in the zebrafish eye
    • Lee J., and Gross J.M. Laminin {beta}1 and {gamma}1 containing laminins are essential for basement membrane integrity in the zebrafish eye. Invest. Ophthalmol. Vis. Sci. 48 (2007) 2483-2490
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 2483-2490
    • Lee, J.1    Gross, J.M.2
  • 45
    • 34249063755 scopus 로고    scopus 로고
    • Direct non-cell autonomous Pax6 activity regulates eye development in the zebrafish
    • Lesaffre B., Joliot A., Prochiantz A., and Volovitch M. Direct non-cell autonomous Pax6 activity regulates eye development in the zebrafish. Neural. Develop. 2 (2007) 2
    • (2007) Neural. Develop. , vol.2 , pp. 2
    • Lesaffre, B.1    Joliot, A.2    Prochiantz, A.3    Volovitch, M.4
  • 46
    • 0033121076 scopus 로고    scopus 로고
    • Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to Hedgehog signalling
    • Lewis K.E., Concordet J.P., and Ingham P.W. Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to Hedgehog signalling. Dev. Biol. 208 (1999) 14-29
    • (1999) Dev. Biol. , vol.208 , pp. 14-29
    • Lewis, K.E.1    Concordet, J.P.2    Ingham, P.W.3
  • 47
    • 33745280126 scopus 로고    scopus 로고
    • The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans
    • Liegeois S., Benedetto A., Garnier J.M., Schwab Y., and Labouesse M. The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans. J. Cell Biol. 173 (2006) 949-961
    • (2006) J. Cell Biol. , vol.173 , pp. 949-961
    • Liegeois, S.1    Benedetto, A.2    Garnier, J.M.3    Schwab, Y.4    Labouesse, M.5
  • 48
    • 33751085162 scopus 로고    scopus 로고
    • Hedgehog signaling and the retina: insights into the mechanisms controlling the proliferative properties of neural precursors
    • Locker M., Agathocleous M., Amato M.A., Parain K., Harris W.A., and Perron M. Hedgehog signaling and the retina: insights into the mechanisms controlling the proliferative properties of neural precursors. Genes Dev. 20 (2006) 3036-3048
    • (2006) Genes Dev. , vol.20 , pp. 3036-3048
    • Locker, M.1    Agathocleous, M.2    Amato, M.A.3    Parain, K.4    Harris, W.A.5    Perron, M.6
  • 49
    • 0028864430 scopus 로고
    • Midline signalling is required for Pax gene regulation and patterning of the eyes
    • Macdonald R., Barth K.A., Xu Q., Holder N., Mikkola I., and Wilson S.W. Midline signalling is required for Pax gene regulation and patterning of the eyes. Development 121 (1995) 3267-3278
    • (1995) Development , vol.121 , pp. 3267-3278
    • Macdonald, R.1    Barth, K.A.2    Xu, Q.3    Holder, N.4    Mikkola, I.5    Wilson, S.W.6
  • 50
    • 0030762576 scopus 로고    scopus 로고
    • The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain
    • Macdonald R., Scholes J., Strahle U., Brennan C., Holder N., Brand M., and Wilson S.W. The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain. Development 124 (1997) 2397-2408
    • (1997) Development , vol.124 , pp. 2397-2408
    • Macdonald, R.1    Scholes, J.2    Strahle, U.3    Brennan, C.4    Holder, N.5    Brand, M.6    Wilson, S.W.7
  • 53
    • 0036333371 scopus 로고    scopus 로고
    • The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye
    • Mui S.H., Hindges R., O'Leary D.D., Lemke G., and Bertuzzi S. The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development 129 (2002) 797-804
    • (2002) Development , vol.129 , pp. 797-804
    • Mui, S.H.1    Hindges, R.2    O'Leary, D.D.3    Lemke, G.4    Bertuzzi, S.5
  • 54
    • 18844396117 scopus 로고    scopus 로고
    • Vax genes ventralize the embryonic eye
    • Mui S.H., Kim J.W., Lemke G., and Bertuzzi S. Vax genes ventralize the embryonic eye. Genes Dev. 19 (2005) 1249-1259
    • (2005) Genes Dev. , vol.19 , pp. 1249-1259
    • Mui, S.H.1    Kim, J.W.2    Lemke, G.3    Bertuzzi, S.4
  • 56
    • 0032946360 scopus 로고    scopus 로고
    • Vacuolar and plasma membrane proton-adenosinetriphosphatases
    • Nelson N., and Harvey W.R. Vacuolar and plasma membrane proton-adenosinetriphosphatases. Physiol. Rev. 79 (1999) 361-385
    • (1999) Physiol. Rev. , vol.79 , pp. 361-385
    • Nelson, N.1    Harvey, W.R.2
  • 58
    • 0036481562 scopus 로고    scopus 로고
    • The vacuolar (H +)-ATPases-nature's most versatile proton pumps
    • Nishi T., and Forgac M. The vacuolar (H +)-ATPases-nature's most versatile proton pumps. Nat. Rev. Mol. Cell Biol. 3 (2002) 94-103
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 94-103
    • Nishi, T.1    Forgac, M.2
  • 59
    • 0033061653 scopus 로고    scopus 로고
    • Expression of the Vax family homeobox genes suggests multiple roles in eye development
    • Ohsaki K., Morimitsu T., Ishida Y., Kominami R., and Takahashi N. Expression of the Vax family homeobox genes suggests multiple roles in eye development. Genes Cells 4 (1999) 267-276
    • (1999) Genes Cells , vol.4 , pp. 267-276
    • Ohsaki, K.1    Morimitsu, T.2    Ishida, Y.3    Kominami, R.4    Takahashi, N.5
  • 60
    • 0032518299 scopus 로고    scopus 로고
    • Pax2 expression and retinal morphogenesis in the normal and Krd mouse
    • Otteson D.C., Shelden E., Jones J.M., Kameoka J., and Hitchcock P.F. Pax2 expression and retinal morphogenesis in the normal and Krd mouse. Dev. Biol. 193 (1998) 209-224
    • (1998) Dev. Biol. , vol.193 , pp. 209-224
    • Otteson, D.C.1    Shelden, E.2    Jones, J.M.3    Kameoka, J.4    Hitchcock, P.F.5
  • 61
    • 0037730213 scopus 로고    scopus 로고
    • A novel function for Hedgehog signalling in retinal pigment epithelium differentiation
    • Perron M., Boy S., Amato M.A., Viczian A., Koebernick K., Pieler T., and Harris W.A. A novel function for Hedgehog signalling in retinal pigment epithelium differentiation. Development 130 (2003) 1565-1577
    • (2003) Development , vol.130 , pp. 1565-1577
    • Perron, M.1    Boy, S.2    Amato, M.A.3    Viczian, A.4    Koebernick, K.5    Pieler, T.6    Harris, W.A.7
  • 64
    • 0036076390 scopus 로고    scopus 로고
    • Axes establishment during eye morphogenesis in Xenopus by coordinate and antagonistic actions of BMP4, Shh, and RA
    • Sasagawa S., Takabatake T., Takabatake Y., Muramatsu T., and Takeshima K. Axes establishment during eye morphogenesis in Xenopus by coordinate and antagonistic actions of BMP4, Shh, and RA. Genesis 33 (2002) 86-96
    • (2002) Genesis , vol.33 , pp. 86-96
    • Sasagawa, S.1    Takabatake, T.2    Takabatake, Y.3    Muramatsu, T.4    Takeshima, K.5
  • 65
    • 0031716102 scopus 로고    scopus 로고
    • Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish
    • Schauerte H.E., van Eeden F.J., Fricke C., Odenthal J., Strahle U., and Haffter P. Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish. Development 125 (1998) 2983-2993
    • (1998) Development , vol.125 , pp. 2983-2993
    • Schauerte, H.E.1    van Eeden, F.J.2    Fricke, C.3    Odenthal, J.4    Strahle, U.5    Haffter, P.6
  • 66
    • 0033738874 scopus 로고    scopus 로고
    • Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6
    • Schwarz M., Cecconi F., Bernier G., Andrejewski N., Kammandel B., Wagner M., and Gruss P. Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6. Development 127 (2000) 4325-4334
    • (2000) Development , vol.127 , pp. 4325-4334
    • Schwarz, M.1    Cecconi, F.2    Bernier, G.3    Andrejewski, N.4    Kammandel, B.5    Wagner, M.6    Gruss, P.7
  • 67
    • 0037158748 scopus 로고    scopus 로고
    • Patched acts catalytically to suppress the activity of Smoothened
    • Taipale J., Cooper M.K., Maiti T., and Beachy P.A. Patched acts catalytically to suppress the activity of Smoothened. Nature 418 (2002) 892-897
    • (2002) Nature , vol.418 , pp. 892-897
    • Taipale, J.1    Cooper, M.K.2    Maiti, T.3    Beachy, P.A.4
  • 68
    • 0037348570 scopus 로고    scopus 로고
    • Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity
    • Take-uchi M., Clarke J.D., and Wilson S.W. Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development 130 (2003) 955-968
    • (2003) Development , vol.130 , pp. 955-968
    • Take-uchi, M.1    Clarke, J.D.2    Wilson, S.W.3
  • 69
    • 0029953417 scopus 로고    scopus 로고
    • Pax2 contributes to inner ear patterning and optic nerve trajectory
    • Torres M., Gomez-Pardo E., and Gruss P. Pax2 contributes to inner ear patterning and optic nerve trajectory. Development 122 (1996) 3381-3391
    • (1996) Development , vol.122 , pp. 3381-3391
    • Torres, M.1    Gomez-Pardo, E.2    Gruss, P.3
  • 71
    • 25444508919 scopus 로고    scopus 로고
    • Analysis of the Zebrafish perplexed mutation reveals tissue-specific roles for de novo pyrimidine synthesis during development
    • Willer G.B., Lee V.M., Gregg R.G., and Link B.A. Analysis of the Zebrafish perplexed mutation reveals tissue-specific roles for de novo pyrimidine synthesis during development. Genetics 170 (2005) 1827-1837
    • (2005) Genetics , vol.170 , pp. 1827-1837
    • Willer, G.B.1    Lee, V.M.2    Gregg, R.G.3    Link, B.A.4
  • 72
    • 0038376480 scopus 로고    scopus 로고
    • Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo
    • Wolff C., Roy S., and Ingham P.W. Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo. Curr. Biol. 13 (2003) 1169-1181
    • (2003) Curr. Biol. , vol.13 , pp. 1169-1181
    • Wolff, C.1    Roy, S.2    Ingham, P.W.3
  • 73
    • 7244255752 scopus 로고    scopus 로고
    • Hedgehog signalling controls eye degeneration in blind cavefish
    • Yamamoto Y., Stock D.W., and Jeffery W.R. Hedgehog signalling controls eye degeneration in blind cavefish. Nature 431 (2004) 844-847
    • (2004) Nature , vol.431 , pp. 844-847
    • Yamamoto, Y.1    Stock, D.W.2    Jeffery, W.R.3
  • 74
    • 0035872915 scopus 로고    scopus 로고
    • Temporal and spatial effects of Sonic hedgehog signaling in chick eye morphogenesis
    • Zhang X.M., and Yang X.J. Temporal and spatial effects of Sonic hedgehog signaling in chick eye morphogenesis. Dev. Biol. 233 (2001) 271-290
    • (2001) Dev. Biol. , vol.233 , pp. 271-290
    • Zhang, X.M.1    Yang, X.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.