메뉴 건너뛰기




Volumn 32, Issue 1, 2008, Pages 33-47

The rôle of control and system theory in systems biology

Author keywords

Biology; Computational physiology; Control systems; Estimation; Mathematical biology; System identification; Systems biology; Systems dynamics

Indexed keywords

AUTOMATION; DISEASES; IDENTIFICATION (CONTROL SYSTEMS); LIVING SYSTEMS STUDIES; MATHEMATICAL MODELS; PHYSIOLOGY;

EID: 44749086859     PISSN: 13675788     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcontrol.2008.02.001     Document Type: Article
Times cited : (40)

References (132)
  • 3
    • 32044452595 scopus 로고    scopus 로고
    • Alberghina L., and Westerhoff H.V. (Eds), Springer, Berlin
    • In: Alberghina L., and Westerhoff H.V. (Eds). Systems biology: Definitions and perspectives (2005), Springer, Berlin
    • (2005) Systems biology: Definitions and perspectives
  • 5
    • 33745075591 scopus 로고    scopus 로고
    • Tools for kinetic modeling of biochemical networks
    • Alves R., Antunes F., and Salvador A. Tools for kinetic modeling of biochemical networks. Nature Biotechnology 24 (2006) 667-672
    • (2006) Nature Biotechnology , vol.24 , pp. 667-672
    • Alves, R.1    Antunes, F.2    Salvador, A.3
  • 8
    • 0034914737 scopus 로고    scopus 로고
    • A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model
    • Asthagiri A.R., and Lauffenburger D.A. A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model. Biotechnology Progress 17 (2001) 239-277
    • (2001) Biotechnology Progress , vol.17 , pp. 239-277
    • Asthagiri, A.R.1    Lauffenburger, D.A.2
  • 10
    • 0742305866 scopus 로고    scopus 로고
    • Network biology: Understanding the cell's functional organisation
    • Barabasi A.L., and Oltvai Z.N. Network biology: Understanding the cell's functional organisation. Nature Reviews. Genetics 5 (2004) 101-113
    • (2004) Nature Reviews. Genetics , vol.5 , pp. 101-113
    • Barabasi, A.L.1    Oltvai, Z.N.2
  • 12
    • 84956739645 scopus 로고    scopus 로고
    • Beck S., and Olek A. (Eds), Wiley-VCH, Weinheim
    • In: Beck S., and Olek A. (Eds). The epigenome: Molecular hide and seek (2003), Wiley-VCH, Weinheim
    • (2003) The epigenome: Molecular hide and seek
  • 13
    • 44749083557 scopus 로고    scopus 로고
    • BioModels Database. (2006). www.biomodels.net.
    • BioModels Database. (2006). www.biomodels.net.
  • 15
    • 32544439820 scopus 로고    scopus 로고
    • On the robustness of centrality measures under conditions of imperfect data
    • Borgatti S., Carley K., and Krackhardt D. On the robustness of centrality measures under conditions of imperfect data. Social Networks 28 (2006) 124-136
    • (2006) Social Networks , vol.28 , pp. 124-136
    • Borgatti, S.1    Carley, K.2    Krackhardt, D.3
  • 17
    • 32044452595 scopus 로고    scopus 로고
    • Bringman P., Butcher E.C., Parry G., and Weiss B. (Eds), Springer
    • In: Bringman P., Butcher E.C., Parry G., and Weiss B. (Eds). Systems biology: Applications and perspectives (2007), Springer
    • (2007) Systems biology: Applications and perspectives
  • 21
  • 22
    • 44749091468 scopus 로고    scopus 로고
    • cellML Model Repository. (2006). http://www.cellml.org/models.
    • cellML Model Repository. (2006). http://www.cellml.org/models.
  • 25
    • 3142617691 scopus 로고    scopus 로고
    • Mathematical and computational techniques to deduce complex biochemical reaction mechanisms
    • Crampin E.J., Schell S., and McSharry P.E. Mathematical and computational techniques to deduce complex biochemical reaction mechanisms. Progress in Biophysics and Molecular Biology 86 (2004) 77-112
    • (2004) Progress in Biophysics and Molecular Biology , vol.86 , pp. 77-112
    • Crampin, E.J.1    Schell, S.2    McSharry, P.E.3
  • 26
    • 0036500834 scopus 로고    scopus 로고
    • Reverse engineering of biological complexity
    • Csete C., and Doyle J. Reverse engineering of biological complexity. Science 295 (2006) 1664-1669
    • (2006) Science , vol.295 , pp. 1664-1669
    • Csete, C.1    Doyle, J.2
  • 29
    • 0032580202 scopus 로고    scopus 로고
    • Calcium oscillations increase the efficiency and specificity of gene expression
    • Dolmetsch R.E., Xu K., and Lewis R.S. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 392 (1998) 933-936
    • (1998) Nature , vol.392 , pp. 933-936
    • Dolmetsch, R.E.1    Xu, K.2    Lewis, R.S.3
  • 31
    • 0035859030 scopus 로고    scopus 로고
    • The ins and outs of signalling
    • Downward J. The ins and outs of signalling. Nature 411 (2001) 759-762
    • (2001) Nature , vol.411 , pp. 759-762
    • Downward, J.1
  • 32
    • 31344478575 scopus 로고    scopus 로고
    • Virtual identification of essential proteins within the protein interaction network of yeast
    • Estrada E. Virtual identification of essential proteins within the protein interaction network of yeast. Proteomics 6 (2006) 35-40
    • (2006) Proteomics , vol.6 , pp. 35-40
    • Estrada, E.1
  • 33
    • 0004207135 scopus 로고    scopus 로고
    • Fall C.P., Marland E.S., Wagner J.M., and Tyson J.J. (Eds), Springer, New York
    • In: Fall C.P., Marland E.S., Wagner J.M., and Tyson J.J. (Eds). Computational cell biology (2002), Springer, New York
    • (2002) Computational cell biology
  • 35
    • 0035108245 scopus 로고    scopus 로고
    • Biocomplexity: Adaptive behavior in complex stochastic dynamical systems
    • Freeman W.J., Kozma R., and Werbos P.J. Biocomplexity: Adaptive behavior in complex stochastic dynamical systems. Biosystems 59 (2001) 109-123
    • (2001) Biosystems , vol.59 , pp. 109-123
    • Freeman, W.J.1    Kozma, R.2    Werbos, P.J.3
  • 37
    • 0142231860 scopus 로고    scopus 로고
    • The unseen genome: Jems among the junk
    • Gibbs W.W. The unseen genome: Jems among the junk. Scientific American 289 (2003) 46-53
    • (2003) Scientific American , vol.289 , pp. 46-53
    • Gibbs, W.W.1
  • 38
    • 0035826148 scopus 로고    scopus 로고
    • Synchronization and rhythmic processes in physiology
    • Glass L. Synchronization and rhythmic processes in physiology. Nature 410 (2001) 277-284
    • (2001) Nature , vol.410 , pp. 277-284
    • Glass, L.1
  • 40
    • 0008849269 scopus 로고    scopus 로고
    • From simple to complex oscillatory behaviour in metabolic and genetic control networks
    • Goldbeter A., Gonze D., Houart G., Lepour J.-C., and Halloy J. From simple to complex oscillatory behaviour in metabolic and genetic control networks. Chaos 11 (2001) 247-260
    • (2001) Chaos , vol.11 , pp. 247-260
    • Goldbeter, A.1    Gonze, D.2    Houart, G.3    Lepour, J.-C.4    Halloy, J.5
  • 46
    • 0036285634 scopus 로고    scopus 로고
    • Mathematical models of protein kinase signal transduction
    • Heinrich R., Neel B.G., and Rappaport T.A. Mathematical models of protein kinase signal transduction. Molecular Cell 9 (2002) 957-970
    • (2002) Molecular Cell , vol.9 , pp. 957-970
    • Heinrich, R.1    Neel, B.G.2    Rappaport, T.A.3
  • 47
    • 0006841532 scopus 로고    scopus 로고
    • Henzinger T.A., and Sastry S. (Eds), Springer-Verlag, Berlin
    • In: Henzinger T.A., and Sastry S. (Eds). Hybrid systems: Computation and control (1998), Springer-Verlag, Berlin
    • (1998) Hybrid systems: Computation and control
  • 48
    • 7444253428 scopus 로고    scopus 로고
    • Systems biology and new technologies enable predictive and preventative medicine
    • Hood L., Heath J.R., Phelps M.E., and Lin B. Systems biology and new technologies enable predictive and preventative medicine. Science 306 (2004) 640-643
    • (2004) Science , vol.306 , pp. 640-643
    • Hood, L.1    Heath, J.R.2    Phelps, M.E.3    Lin, B.4
  • 49
    • 44749083625 scopus 로고    scopus 로고
    • Hunter, P. (March 2005). IUPS Physiome project roadmap. Technical report, University of Auckland. www.physiome.org.nz/roadmap/roadmap-mar05.
    • Hunter, P. (March 2005). IUPS Physiome project roadmap. Technical report, University of Auckland. www.physiome.org.nz/roadmap/roadmap-mar05.
  • 50
  • 51
    • 33947406414 scopus 로고    scopus 로고
    • Multiscale modelling: Physiome project standards, tools and databases
    • Hunter P.J., Li W.W., Mc Culloch A.D., and Noble D. Multiscale modelling: Physiome project standards, tools and databases. Computer 39 (2006) 48-54
    • (2006) Computer , vol.39 , pp. 48-54
    • Hunter, P.J.1    Li, W.W.2    Mc Culloch, A.D.3    Noble, D.4
  • 52
    • 44749087306 scopus 로고    scopus 로고
    • Hucka, M., Finney, A., Sauro, H. M., Bolouri, H., Doyle, J., Kitano, H., et al. (2003). The systems biology markup language (SMBL): A medium for representation and exchange of biochemical networks. Bioinformatics, 419, 523-531.
    • Hucka, M., Finney, A., Sauro, H. M., Bolouri, H., Doyle, J., Kitano, H., et al. (2003). The systems biology markup language (SMBL): A medium for representation and exchange of biochemical networks. Bioinformatics, 419, 523-531.
  • 53
    • 44749084055 scopus 로고    scopus 로고
    • IET Systems Biology. (2006). www.ietdl.org/IP-SYB/.
    • IET Systems Biology. (2006). www.ietdl.org/IP-SYB/.
  • 54
    • 0742304058 scopus 로고    scopus 로고
    • A frequency domain approach to sensitivity analysis of biochemical systems
    • Ingalls B.P. A frequency domain approach to sensitivity analysis of biochemical systems. Journal of Physical Chemistry B 108 (2004) 1143-1152
    • (2004) Journal of Physical Chemistry B , vol.108 , pp. 1143-1152
    • Ingalls, B.P.1
  • 55
    • 0037466509 scopus 로고    scopus 로고
    • Sensitivity analysis of stoichiometric networks: An extension of metabolic control analysis to non-steady state trajectories
    • Ingalls B.P., and Sauro H.M. Sensitivity analysis of stoichiometric networks: An extension of metabolic control analysis to non-steady state trajectories. Journal of Theoretical Biology 222 (2003) 23-36
    • (2003) Journal of Theoretical Biology , vol.222 , pp. 23-36
    • Ingalls, B.P.1    Sauro, H.M.2
  • 56
    • 44749085966 scopus 로고    scopus 로고
    • Institute of Systems Biology. (2006). www.systems-biology.org/001/.
    • Institute of Systems Biology. (2006). www.systems-biology.org/001/.
  • 57
    • 5644285261 scopus 로고    scopus 로고
    • Real-time neural activity and connectivity in healthy individuals and schizophrenia patients
    • Ioannides A.A., Poghosyan V., Dammers J., and Streit M. Real-time neural activity and connectivity in healthy individuals and schizophrenia patients. NeuroImage 23 (2004) 473-482
    • (2004) NeuroImage , vol.23 , pp. 473-482
    • Ioannides, A.A.1    Poghosyan, V.2    Dammers, J.3    Streit, M.4
  • 58
    • 0035799707 scopus 로고    scopus 로고
    • Lethality and centrality in protein networks
    • Jeong H., Mason S., Barabasi A., and Oltvai Z. Lethality and centrality in protein networks. Nature 411 (2001) 41-42
    • (2001) Nature , vol.411 , pp. 41-42
    • Jeong, H.1    Mason, S.2    Barabasi, A.3    Oltvai, Z.4
  • 59
    • 44749092826 scopus 로고    scopus 로고
    • JWS Online. (2006). jjj.biochem.sun.ac.za.
    • JWS Online. (2006). jjj.biochem.sun.ac.za.
  • 64
    • 0004243729 scopus 로고    scopus 로고
    • Kitano H. (Ed), MIT Press, Boston
    • In: Kitano H. (Ed). Foundations of systems biology (2001), MIT Press, Boston
    • (2001) Foundations of systems biology
  • 67
    • 0034667593 scopus 로고    scopus 로고
    • Meaningful relationships: The regulation of the RAS/RAF/MEK/ERK pathway by protein interactions
    • Kolch W. Meaningful relationships: The regulation of the RAS/RAF/MEK/ERK pathway by protein interactions. The Biochemical Journal 351 (2000) 289-305
    • (2000) The Biochemical Journal , vol.351 , pp. 289-305
    • Kolch, W.1
  • 68
    • 0346725930 scopus 로고    scopus 로고
    • Unraveling protein interaction networks with near-optimal efficiency
    • Lappe M., and Holm L. Unraveling protein interaction networks with near-optimal efficiency. Nature Biotechnology 22 1 (2004) 98-103
    • (2004) Nature Biotechnology , vol.22 , Issue.1 , pp. 98-103
    • Lappe, M.1    Holm, L.2
  • 69
    • 0036729047 scopus 로고    scopus 로고
    • Can a biologist fix a radio?
    • Lazebnik Y. Can a biologist fix a radio?. Cancer Cell 2 (2002) 179-182
    • (2002) Cancer Cell , vol.2 , pp. 179-182
    • Lazebnik, Y.1
  • 72
    • 44749089343 scopus 로고    scopus 로고
    • MacFarlane, A. G. J. (2006). Private communication.
    • MacFarlane, A. G. J. (2006). Private communication.
  • 73
    • 0142027814 scopus 로고    scopus 로고
    • Structure and function of the feed-forward loop network motif
    • Mangan S., and Alon U. Structure and function of the feed-forward loop network motif. Proceedings of the National Academy of Sciences 100 21 (2003) 11980-11985
    • (2003) Proceedings of the National Academy of Sciences , vol.100 , Issue.21 , pp. 11980-11985
    • Mangan, S.1    Alon, U.2
  • 74
    • 24044508608 scopus 로고    scopus 로고
    • Logical analysis of biological systems
    • Mardare R., and Priami C. Logical analysis of biological systems. Fundamenta Informaticae 64 (2005) 271-285
    • (2005) Fundamenta Informaticae , vol.64 , pp. 271-285
    • Mardare, R.1    Priami, C.2
  • 75
    • 33947619951 scopus 로고    scopus 로고
    • Graph theory and networks in biology
    • Mason O., and Verwoerd M. Graph theory and networks in biology. IET Systems Biology 1 (2007) 89-119
    • (2007) IET Systems Biology , vol.1 , pp. 89-119
    • Mason, O.1    Verwoerd, M.2
  • 79
    • 44749093647 scopus 로고    scopus 로고
    • Middleton, R., & Wellstead, P. E. (February 2006). On intervention in feedback loops with integral control: Implications for feedback medicine. Technical report, Hamilton Institute.
    • Middleton, R., & Wellstead, P. E. (February 2006). On intervention in feedback loops with integral control: Implications for feedback medicine. Technical report, Hamilton Institute.
  • 81
    • 33747830489 scopus 로고    scopus 로고
    • Quantitative modelling in cell biology: What is it good for?
    • Mogliner A., Wollman R., and Marshall W.F. Quantitative modelling in cell biology: What is it good for?. Developmental Cell 11 (2006) 279-287
    • (2006) Developmental Cell , vol.11 , pp. 279-287
    • Mogliner, A.1    Wollman, R.2    Marshall, W.F.3
  • 83
    • 0036901518 scopus 로고    scopus 로고
    • Modelling of signalling networks
    • Neves S.R., and Iyengar R. Modelling of signalling networks. BioEssays 24 (2002) 1110-1117
    • (2002) BioEssays , vol.24 , pp. 1110-1117
    • Neves, S.R.1    Iyengar, R.2
  • 84
    • 7444254365 scopus 로고    scopus 로고
    • Nelson, D. E., Ihekwaba, A. E. C., Elliott, M., Johnson, J. R., Gibney, C. A., Foreman B. E., et al. (2004). Oscillations in NF- κ B signalling control the dynamics of gene expression. Science, 306, 704-708.
    • Nelson, D. E., Ihekwaba, A. E. C., Elliott, M., Johnson, J. R., Gibney, C. A., Foreman B. E., et al. (2004). Oscillations in NF- κ B signalling control the dynamics of gene expression. Science, 306, 704-708.
  • 85
    • 73849164199 scopus 로고
    • A modification of the Hodgkin-Huxley equations applicable to Purkinje fibre action and pacemaker potentials
    • Noble D. A modification of the Hodgkin-Huxley equations applicable to Purkinje fibre action and pacemaker potentials. Journal of Physiology 160 (1962) 317-352
    • (1962) Journal of Physiology , vol.160 , pp. 317-352
    • Noble, D.1
  • 86
    • 0036499997 scopus 로고    scopus 로고
    • Modelling the heart: From genes to cells to the whole organ
    • Noble D. Modelling the heart: From genes to cells to the whole organ. Science 295 (2002) 1678-1682
    • (2002) Science , vol.295 , pp. 1678-1682
    • Noble, D.1
  • 90
    • 33745463739 scopus 로고    scopus 로고
    • A comprehensive map of the toll-like receptor signalling network
    • Oda K., and Kitano H. A comprehensive map of the toll-like receptor signalling network. Molecular Systems Biology (2006) 2
    • (2006) Molecular Systems Biology , pp. 2
    • Oda, K.1    Kitano, H.2
  • 93
    • 44749091330 scopus 로고    scopus 로고
    • Physiome Project. (2006). www.physiomeproject.org.
    • Physiome Project. (2006). www.physiomeproject.org.
  • 95
    • 0023709196 scopus 로고
    • Metabolic control analysis: A structural approach
    • Reder C. Metabolic control analysis: A structural approach. Journal of Theoretical Biology 135 (1988) 175-201
    • (1988) Journal of Theoretical Biology , vol.135 , pp. 175-201
    • Reder, C.1
  • 97
    • 44749083998 scopus 로고    scopus 로고
    • Systems Biology Markup Language (SBML). (2006). www.sbml.org.
    • Systems Biology Markup Language (SBML). (2006). www.sbml.org.
  • 98
    • 44749086656 scopus 로고    scopus 로고
    • Schmidt, H. (2006). Systems biology toolbox for MATLAB. www.sbtoolbox.org/.
    • Schmidt, H. (2006). Systems biology toolbox for MATLAB. www.sbtoolbox.org/.
  • 99
    • 3442889087 scopus 로고    scopus 로고
    • Identifying feedback mechanisms behind complex cell behaviors
    • Schmidt H., and Jacobsen E.W. Identifying feedback mechanisms behind complex cell behaviors. IEEE Control Systems Magazine 24 (2004) 91-102
    • (2004) IEEE Control Systems Magazine , vol.24 , pp. 91-102
    • Schmidt, H.1    Jacobsen, E.W.2
  • 100
    • 32544443964 scopus 로고    scopus 로고
    • Systems biology toolbox for MATLAB: A computational platform for research in systems biology
    • Schmidt H., and Jirstrand M. Systems biology toolbox for MATLAB: A computational platform for research in systems biology. Bioinformatics 22 (2006) 514-515
    • (2006) Bioinformatics , vol.22 , pp. 514-515
    • Schmidt, H.1    Jirstrand, M.2
  • 104
    • 33645379893 scopus 로고    scopus 로고
    • Molecular systems biology and control
    • Sontag E.D. Molecular systems biology and control. European Journal of Control 11 (2005) 1-40
    • (2005) European Journal of Control , vol.11 , pp. 1-40
    • Sontag, E.D.1
  • 106
    • 4544346660 scopus 로고    scopus 로고
    • Robustness of cellular function
    • Stelling J., Sauer U., Doyle F.J., and Doyle J. Robustness of cellular function. Cell 118 (2004) 675-685
    • (2004) Cell , vol.118 , pp. 675-685
    • Stelling, J.1    Sauer, U.2    Doyle, F.J.3    Doyle, J.4
  • 107
    • 33748339322 scopus 로고    scopus 로고
    • Principles of allostasis: Optimal design, predictive regulation, pathophysiology and rational therapeutics
    • Schulkin J. (Ed), Cambridge University Press
    • Sterling P. Principles of allostasis: Optimal design, predictive regulation, pathophysiology and rational therapeutics. In: Schulkin J. (Ed). Allostasis, homeostasis, and the costs of adaptation (2004), Cambridge University Press
    • (2004) Allostasis, homeostasis, and the costs of adaptation
    • Sterling, P.1
  • 108
    • 17644365470 scopus 로고    scopus 로고
    • The end of naive reductionism: The rise of systems biology or renaissance of physiology
    • Strange K. The end of naive reductionism: The rise of systems biology or renaissance of physiology. American Journal of Physiology. Cell Physiology 288 (2005) 968-974
    • (2005) American Journal of Physiology. Cell Physiology , vol.288 , pp. 968-974
    • Strange, K.1
  • 109
    • 15444372528 scopus 로고    scopus 로고
    • Subnets of scale-free networks are not scale-free: Sampling properties of networks
    • Stumpf M., Wiuf C., and May R. Subnets of scale-free networks are not scale-free: Sampling properties of networks. Proceedings of the National Academy of Sciences 102 12 (2005) 4221-4224
    • (2005) Proceedings of the National Academy of Sciences , vol.102 , Issue.12 , pp. 4221-4224
    • Stumpf, M.1    Wiuf, C.2    May, R.3
  • 110
    • 33947407698 scopus 로고    scopus 로고
    • Analysis of interconnected oscillators by dissipativity theory
    • Stan G.-B., and Sepulchre R. Analysis of interconnected oscillators by dissipativity theory. IEEE Transactions on Automatic Control 52 (2007) 256-270
    • (2007) IEEE Transactions on Automatic Control , vol.52 , pp. 256-270
    • Stan, G.-B.1    Sepulchre, R.2
  • 111
    • 0004279345 scopus 로고
    • Sutherland S. (Ed), Pinter and Martin
    • In: Sutherland S. (Ed). Irrationality (1992), Pinter and Martin
    • (1992) Irrationality
  • 112
    • 44749092388 scopus 로고    scopus 로고
    • The Mathworks. (in press). Simbiology 2.2. www.mathworks.com/products/simbiology.
    • The Mathworks. (in press). Simbiology 2.2. www.mathworks.com/products/simbiology.
  • 113
    • 44749083690 scopus 로고    scopus 로고
    • The Royal Society. (September 2005). Personalised medicine: Hopes and realities. Technical report, The Royal Society.
    • The Royal Society. (September 2005). Personalised medicine: Hopes and realities. Technical report, The Royal Society.
  • 116
    • 0037376655 scopus 로고    scopus 로고
    • Sniffers, buzzers, toggles and blinkers: Dynamics of regulatory and signaling pathways in the cell
    • Tyson J.J., Chen K.C., and Novak B. Sniffers, buzzers, toggles and blinkers: Dynamics of regulatory and signaling pathways in the cell. Current Opinion in Cell Biology 15 (2003) 221-231
    • (2003) Current Opinion in Cell Biology , vol.15 , pp. 221-231
    • Tyson, J.J.1    Chen, K.C.2    Novak, B.3
  • 117
    • 0036601150 scopus 로고    scopus 로고
    • Computational methods for the prediction of protein interactions
    • Valencia A., and Pazos F. Computational methods for the prediction of protein interactions. Current Opinion in Structural Biology 12 (2002) 368-373
    • (2002) Current Opinion in Structural Biology , vol.12 , pp. 368-373
    • Valencia, A.1    Pazos, F.2
  • 119
    • 0028108519 scopus 로고
    • Metabolic flux balancing
    • Varma A., and Palsson B.O. Metabolic flux balancing. Biotechnology 12 (1994) 994-998
    • (1994) Biotechnology , vol.12 , pp. 994-998
    • Varma, A.1    Palsson, B.O.2
  • 120
    • 44749090141 scopus 로고    scopus 로고
    • Vera, J., Balsa-Canto, E., Wellstead, P., Banga, J. R., & Wolkenhauer, O. (in press). Power-law models of signal transduction pathways. Cellular Signalling.
    • Vera, J., Balsa-Canto, E., Wellstead, P., Banga, J. R., & Wolkenhauer, O. (in press). Power-law models of signal transduction pathways. Cellular Signalling.
  • 121
    • 44749084220 scopus 로고    scopus 로고
    • Vidyasagar, M., Khammash, M., & Tomlin, C. (Eds.). (January 2008). Joint special issue on systems biology. IEEE Transactions on Automatic Control & IEEE Transactions on Circuits and Systems.
    • Vidyasagar, M., Khammash, M., & Tomlin, C. (Eds.). (January 2008). Joint special issue on systems biology. IEEE Transactions on Automatic Control & IEEE Transactions on Circuits and Systems.
  • 122
    • 17444387728 scopus 로고    scopus 로고
    • Voigt, C. A., Wolf, D. M., Arkin, A. P. (2006). The Bacillus subtilis sin operon: An evolvable network motif. Genetics, 169, 1187-1202.
    • Voigt, C. A., Wolf, D. M., Arkin, A. P. (2006). The Bacillus subtilis sin operon: An evolvable network motif. Genetics, 169, 1187-1202.
  • 125
    • 4644335402 scopus 로고    scopus 로고
    • Systems biology, proteomics, and the future of healthcare: Towards predictive, preventative and personalised medicine
    • Weston A.D., and Hood L. Systems biology, proteomics, and the future of healthcare: Towards predictive, preventative and personalised medicine. Journal of Proteome Research 3 (2004) 179-196
    • (2004) Journal of Proteome Research , vol.3 , pp. 179-196
    • Weston, A.D.1    Hood, L.2
  • 128
    • 44749085634 scopus 로고    scopus 로고
    • Wolkenhauer, O., & Hofmeyr, J.-H. S. (in press). An abstract cell model that describes the self-organisation of cell function in living systems. Journal of Theoretical Biology.
    • Wolkenhauer, O., & Hofmeyr, J.-H. S. (in press). An abstract cell model that describes the self-organisation of cell function in living systems. Journal of Theoretical Biology.
  • 129
    • 44749091055 scopus 로고    scopus 로고
    • Wolkenhauer, O., Mesarović, M., Sreenath, S., Wellstead, P., & Rolfs, A. (2006). Regulation. Chapter from regulation, control and adaptation to the coordination of cell function. Vienna series of theoretical biology. Boston: MIT Press.
    • Wolkenhauer, O., Mesarović, M., Sreenath, S., Wellstead, P., & Rolfs, A. (2006). Regulation. Chapter from regulation, control and adaptation to the coordination of cell function. Vienna series of theoretical biology. Boston: MIT Press.
  • 132
    • 33847051248 scopus 로고    scopus 로고
    • Zhang, L. V., King, O. D., Wong, S. L., Goldberg, D. S., Tong, A. H. Y., Lesage, G., et al. (2005). Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network. Journal of Biology, 4, 6.
    • Zhang, L. V., King, O. D., Wong, S. L., Goldberg, D. S., Tong, A. H. Y., Lesage, G., et al. (2005). Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network. Journal of Biology, 4, 6.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.