Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics

European Journal of Cancer

Volumn 44, Issue 9, 2008, Pages 1290-1301

  Deng, Guoren ^a,b   Kakar, Sanjay ^a,b   Tanaka, Hirofumi ^c   Matsuzaki, Koji ^c   Miura, Soichiro ^c   Sleisenger, Marvin H ^a,b   Kim, Young S ^a,b  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Colorectal cancer; DNA methylation; Gene mutations; Loss of heterozygosity; Microsatellite instability

Indexed keywords

ADENINE; GUANINE;

ADULT; AGED; ARTICLE; BRAF GENE; CANCER SURVIVAL; COLORECTAL CANCER; CPG ISLAND; DNA METHYLATION; EPIGENETICS; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC MARKER; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MALIGNANT TRANSFORMATION; ONCOGENE; ONCOGENE K RAS; P53 GENE; PRIORITY JOURNAL;

AGED; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; FEMALE; GENE DELETION; GENES, NEOPLASM; GENETIC MARKERS; HUMANS; LOSS OF HETEROZYGOSITY; MALE; NEOPLASM PROTEINS; PHENOTYPE;

EID: 44449146998     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2008.03.014     Document Type: Article

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