Inhibition of a membrane complement regulatory protein by a monoclonal antibody induces acute lethal shock in rats primed with lipopolysaccharide

Journal of Immunology

Volumn 162, Issue 9, 1999, Pages 5477-5482

  Mizuno, Masashi ^a   Nishikawa, Kazuhiro ^a   Okada, Noriko ^b   Matsuo, Seiichi ^a   Ito, Kenichi ^a   Okada, Hidechika ^b  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C5A RECEPTOR; HEXAPEPTIDE; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; SNAKE VENOM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; LETHALITY; LEUKOCYTE COUNT; LEUKOPENIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTIC SHOCK;

ACUTE DISEASE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, SURFACE; BLOOD PRESSURE; COBRA VENOMS; COMPLEMENT C5A; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT SYSTEM PROTEINS; CYCLOPHOSPHAMIDE; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; LEUKOPENIA; LIPOPOLYSACCHARIDES; MALE; RATS; RATS, WISTAR; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, CELL SURFACE; RECEPTORS, COMPLEMENT; SHOCK, SEPTIC;

EID: 0033136296     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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