The effect of quercetin on pro-apoptotic activity of cisplatin in HeLa cells

Biochemical Pharmacology

Volumn 69, Issue 9, 2005, Pages 1343-1350

  Jakubowicz Gil, J ^a   Paduch, R ^a   Piersiak, T ^a   Glowniak K ^b   Gawron, A ^a   Kandefer Szerszen M ^a  

^a MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Apoptosis; Cisplatin; HeLa cells; Hsp72; MRP; Quercetin

Indexed keywords

CASPASE 3; CISPLATIN; HEAT SHOCK PROTEIN 72; MULTIDRUG RESISTANCE PROTEIN; QUERCETIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURE MEDIUM; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; HELA CELL; HUMAN; HUMAN CELL; INCUBATION TIME; PRIORITY JOURNAL; SENSITIZATION;

EID: 17044409995     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.01.022     Document Type: Article

References (66)

1. F.G. Blankenberg Recent advances in the imaging of programmed cell death Curr Pharm Des 10 2004 1457 1467
2. C.A. Guimarães, and R. Linden Programmed cell death. Apoptosis and alternative deathstyles Eur J Biochem 271 2004 1638 1650
3. E. Křepela Cysteine proteinases in tumour cell growth and apoptosis Neoplasma 48 2001 332 349
4. S.J. Martin, and D.R. Green Protease activation during apoptosis: death by a thousand cuts? Cell 82 1995 349 352
5. P. Kamarajan, N.-K. Sun, Ch.-L. Sun, and Ch.C.-K. Chao Apaf-1 overexpression partially overcomes apoptotic resistance in a cisplatin-selected HeLa cell line FEBS Lett 505 2001 206 212
6. M. Jäättelä Escaping cell death: survival proteins in cancer Exp Cell Res 248 1999 30 43
7. Z. Ding, X. Yang, A. Pater, and S.-Ch. Tang Resistance to apoptosis is correlated with the reduced caspase-3 activation and enhanced expression of antiapoptotic protein in human cervical multidrug-resistant cells Biochem Biophys Res Commun 270 2000 415 420
8. S. Akiyama, Z.S. Chen, T. Sumizawa, and T. Furukawa Resistance to cisplatin Anti-Cancer Drug Des 14 1999 143 151
9. J. Melendez-Zajgla, C. Garcia, and V. Maldonado Subcellular redistribution of hsp 72 protein during cisplatin-induced apoptosis in Hela cells Biochem Mol Biol Int 40 1996 153 261
10. G. Speelmans, R.W.H.M. Staffhrost, K. Versluis, J. Reedijk, and B. de Kruijff Cisplatin complexes with phosphatydyloserine in membranes Biochemistry 36 1997 10545 10550
11. Hettinga JVE, W. Lemstra, C. Meijer, G. Los, E.G.E. De Vries, and A.W.T. Konings Heat shock protein expression in cisplatin sensitive and resistant human tumour cells Int J Cancer 67 1996 800 807
12. M. Beissinger, and J. Buchner How chaperones fold proteins Biol Chem 379 1998 245 259
13. J.I. Clark Therapeutic applications of heat shock proteins and molecular chaperones Expert Opin Therapeut Patents 11 2001 1153 1160
14. R.J. Ellis Steric chaperones TIBS 23 1998 43 45
15. E. Schwarz, L. Hauke, and R. Rainer The effect of molecular chaperones on in vivo and in vitro folding processes Biol Chem 377 1996 411 416
16. A. Schober, E. Müller, K. Thurau, and F.X. Beck The response of heat shock proteins 25 and 72 to ischaemia in different kidney zones Eur J Physiol 434 1997 292 299
17. W.J. Welch Mammalian stress response: cell physiology, structure/function of stress proteins and implication for medicine and disease Physiol Rev 72 1992 1063 1081
18. E.M. Creagh, D. Sheehan, and T.G. Cotter Heat shock proteins-modulators of apoptosis in tumour cells Leukemia 14 2000 1161 1173
19. C. Jolly, and R.I. Morimoto Role of heat shock response and molecular chaperones in oncogenesis and cell death J Nat Cancer Inst 92 2000 1564 1572
20. C. Sarto, P.-A. Binz, and P. Mocarelli Heat shock proteins in human cancer Electrophoresis 21 2000 1218 1226
21. L. Čipák, P. Rauko, E. Miadoková, I. Čipáková, and L. Novotný Effects of flavonoids on cisplatin-induced apoptosis of HL-60 and L1210 leukemia cells Leukemia Res 27 2003 65 72
22. M.K. Kuhlmann, E. Horsch, G. Burkhardt, M. Wagner, and Köhler Reduction of cisplatin toxicity in cultured renal tubular cells by the bioflavonoid quercetin Arch Toxicol 72 1998 536 540
23. D.F. Birt, S. Hendrich, and W. Wang Dietary agents in cancer prevention: flavonoids and isoflavonoids Pharmacol Therapeut 90 2001 157 177
24. G.G. Duthie, S.J. Duthie, and J.A.M. Kyle Plant polyphenols in cancer and heart disease: implications as nutritional antioxidants Nutr Res Rev 13 2000 79 106
25. L.L. Marchand Cancer preventive effects of flavonoids - a review Biomed Pharmacother 56 2002 296 301
26. S. Balabhadrapathruni, T.J. Thomas, E.J. Yurkow, P.S. Amenta, and T. Thomas Effects of genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells Oncol Rep 7 2000 3 12
27. B. Csokay, N. Prajda, G. Weber, and E. Olah Molecular mechanisms in the antiproliferative action of quercetin Life Sci 60 1997 2157 2163
28. G. Ferrandina, G. Almadori, N. Maggiano, P. Lanza, C. Ferlini, and P. Cattani Growth-inhibitory effect of tamoxifen and quercetin and presence of type II estrogen binding sites in human laryngeal cancer cell lines and primary laryngeal tumors Int J Cancer 7 1998 747 754
29. W. Li, F. Shen, and G. Weber Ribavidin and quercetin synergistically downregulate signal transduction and are cytotoxic in human ovarian carcinoma cells Oncol Res 11 1999 243 247
30. M.D. Losiewicz, B.A. Carlson, G. Kaur, E.A. Sausville, and P.J. Worland Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275 Biochem Biophys Res Commun 201 1994 589 595
31. F.O. Ranelletti, N. Maggiano, F.G. Serra, R. Ricci, L.M. Larocca, and P. Lanza Quercetin inhibits p21-RAS expression in human colon cancer cell lines and in primary colorectal tumors Int J Cancer 85 2000 438 445
32. E.H. Walker, M.E. Pacold, O. Perisic, L. Stephens, P.T. Hawkins, and M.P. Wymann Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine Mol Cell 6 2000 909 919
33. G. Weber, F. Shen, N. Prajda, H. Yang, W. Li, and A. Yeh Regulation of the signal transduction program by drugs Adv Enzyme Regul 37 1997 35 55
34. M. Yoshida, T. Sakai, N. Hosokawa, N. Marui, K. Matsumoto, and A. Fujioka The effect of quercetin on cell cycle progression and growth of human gastric cancer cells FEBS Lett 260 1990 10 13
35. 1 phase of the cell cycle Cancer Res 52 1992 6676 6681
36. M. Russo, R. Palumbo, I. Tedesco, G. Mazzarella, P. Russo, and G. Iacomino Quercetin and anti-CD95 (FAS/Apo1) enhance apoptosis in HPB-ALL cell line FEBS Lett 462 1999 322 328
37. J. Jakubowicz-Gil, R. Paduch, A. Gawron, and M. Kandefer-Szerszeń The effect of heat shock, cisplatin, etoposide and quercetin on Hsp27 expression in human normal and tumour cells Folia Histochem Cytobiol 40 2002 31 35
38. J. Jakubowicz-Gil, R. Paduch, A. Gawron, and M. Kandefer-Szerszeń The effect of cisplatin, etoposide and quercetin on Hsp72 expression Pol J Pathol 53 2002 133 137
39. J. Jakubowicz-Gil, J. Rzymowska, and A. Gawron Quercetin apoptosis, heat shock Biochem Pharmacol 64 2002 1591 1595
40. W. Hu, W. Wu, C.F. Verschraegen, L. Chen, L. Mao, and S.C. Yeung Proteomic identification of heat shock protein 70 as a candidate target for enhancing apoptosis induced by farnesyl transferase inhibitor Proteomics 3 2003 1904 1911
41. T. Sasada, H. Nakamura, S. Ueda, N. Sato, Y. Kitaoka, and Y. Gon Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II) Free Rad Biol Med 27 1999 504 514
42. V. Maldonado, J. Melendez, H. Gonzalez, and A. Ortega Internucleosomal DNA cleavage in HeLa cells exposed to cisplatin Biochem Mol Biol Int 37 1995 691 696
43. M.M. Bradford A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 1976 248 254
44. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
45. A. Jankowska, D. Skonieczna, Rommerts FFC, and J.B. Warchoł Investigations on apoptosis in Leydig cells cultured in vitro Folia Histochem Cytobiol 33 1997 99 110
46. N.C. Cook, and S. Samman Flavonoids-chemistry, metabolism, cardioprotective effects and dietary sources Nutr Biochem 7 1996 66 76
47. P.C. Hollman, and M.B. Katan Dietary flavonoids: intake, health effects and bioavailability Food Chem Toxicol 37 1999 937 942
48. I. Morel, G. Lescoat, P. Cogrel, O. Sergent, N. Pasdeloup, and P. Brissot Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures Biochem Pharmacol 45 1993 13 19
49. L. Čipák, L. Novotný, I. Čipá ková, and P. Rauko Differential modulation of cisplatin and doxorubicin efficacies in leukemia cells by flavonoids Nutr Res 23 2003 1045 1057
50. I.-K. Wang, S.-Y. Lin-Shiau, and J.-K. Lin Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells Eur J Cancer 15 1999 1517 1525
51. N. Hosokawa, K. Hirayoshi, H. Kudo, H. Takechi, A. Aoike, and K. Kawai Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids Mol Cell Biol 12 1992 3490 3498
52. R.K. Hansen, S. Oesterreich, P. Lemieux, K.D. Sarge, and S.A.W. Fuqua Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells Biochem Biophym Res Commun 239 1997 851 856
53. Y. Nagasaka, and K. Nakamura Modulation of the heat-induced activation of mitogen-activated protein (MAP) kinase by quercetin Biochem Pharmacol 56 1998 1151 1155
54. S. Ellis, M. Killender, and R.L. Anderson Heat-induced alterations in the localization of Hsp72 and Hsp73 as measured by indirect immunohistochemistry and immunogold electron microscopy J Histochem Cytochem 48 2000 321 331
55. K. Milarski, W.J. Welch, and R.I. Morimoto Cell cycle-dependent association of Hsp72 with specific cellular proteins J Cell Biol 108 1989 413 423
56. W.J. Welch, and J.R. Ferasmico Nuclear and nucleolar localization of the 72 000-Dalton heat shock protein in heat shocked mammalian cells J Biol Chem 259 1984 4501 4513
57. W.J. Welch, and J.P. Suhan Cellular and biochemical events in mammalian cells during and after recovery from physiological stress J Cell Biol 103 1986 2035 2052
58. B. Pawlikowska-Pawlȩga, W.I. Gruszecki, L.E. Misiak, and A. Gawron The study of the quercetin action on human erythrocyte membrane Biochem Pharmacol 66 2003 605 612
59. M.J. Laughton, B. Halliwell, P.J. Evans, and J.R. Hoult Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin. Effects on lipid peroxidation, hydroxyl radical generation and bleomycin-dependent damage to DNA Biochem Pharmacol 38 1989 2859 2865
60. N. Sugihara, T. Arakawa, M. Ohnishi, and K. Furuno Anti- and pro-oxidative effects of flavonoids on metal-induced lipid hydroperoxide- dependent lipid peroxidation in cultured hepatocytes loaded with alpha-linolenic acid Free Rad Biol Med 27 1999 1313 1323
61. R.P. Perez Cellular and molecular determinants of cisplatin resistance Eur J Cancer 34 1998 1535 1542
62. K. Zhang, M. Chew, E.B. Yang, L.P. Wong, and P. Mack Modulation of cisplatin cytotoxicity and cisplatin-induced DNA cross-links in HepG2 cells by regulation of glutathione-related mechanisms Mol Pharmacol 59 2001 837 843
63. T. Ishikawa The ATP-dependent glutathione S-conjugate export pump Trends Biochem Sci 17 1992 463 468
64. T. Ishikawa, C.D. Wright, and H. Ishizuka GS-X pump is functionally overexpressed in cis-diamminedichloroplatinum (II)-resistant human leukemia HL-60 cells and down-regulated by cell differentiation J Biol Chem 269 1994 29085 29093
65. D.W. Nicholson Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis Nature 376 1995 37 43
66. R. Ran, G. Zhou, A. Lu, L. Zhang, Y. Tang, and A.C. Rigby Hsp70 mutant proteins modulate additional apoptotic pathways and improve cell survival Cell Stress Chaperones 9 2004 229 242