Gastroprotective action of orexin-A against stress-induced gastric damage is mediated by endogenous prostaglandins, sensory afferent neuropeptides and nitric oxide

Regulatory Peptides

Volumn 148, Issue 1-3, 2008, Pages 6-20

  Brzozowski, Tomasz ^a   Konturek, Peter C ^b   Sliwowski, Zbigniew ^a   Drozdowicz, Danuta ^a   Burnat, Grzegorz ^b   Pajdo, Robert ^a   Pawlik, Michal ^a   Bielanski, Wladyslaw ^a   Kato, Ikuo ^c   Kuwahara, Atsuzakau ^c   Konturek, Stanislaw J ^a   Pawlik, Wieslaw W ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c Yanaihara Institute Inc   (Japan)

Author keywords

Calcitonin gene related peptide; Gastric blood flow; Gastroprotection; Nitric oxide; Orexin A; Prostaglandins; Sensory nerves; Stress; Vagal nerves

Indexed keywords

ALCOHOL; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CAPSAZEPINE; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ B RECEPTOR ANTAGONIST; CYCLOOXYGENASE 2; GASTRIN; GASTRIN RECEPTOR; MESSENGER RNA; NEUROPEPTIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OREXIN A; PEPSIN A; PROSTAGLANDIN; PROSTAGLANDIN E2; RPR 102681;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GASTRIN RELEASE; HISTOLOGY; MALE; NONHUMAN; PEPSIN SECRETION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE; STATISTICAL ANALYSIS; STOMACH BLOOD FLOW; STOMACH PROTECTION; STOMACH SECRETION; STRESS ULCER; VAGOTOMY; VAGUS NERVE;

ANIMALS; BLOTTING, WESTERN; CALCITONIN GENE-RELATED PEPTIDE; CYCLOOXYGENASE 2; GASTRIC ACID; GASTRIC MUCOSA; GASTRINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NEUROPEPTIDES; NITRIC OXIDE; PROSTAGLANDINS; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH DISEASES; STRESS;

RATTUS;

EID: 44349090953     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2008.02.003     Document Type: Article

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