Secreted form of amyloid precursor protein enhances basal glucose and glutamate transport and protects against oxidative impairment of glucose and glutamate transport in synaptosomes by a cyclic GMP-mediated mechanism

Journal of Neurochemistry

Volumn 73, Issue 2, 1999, Pages 532-537

  Mattson, Mark P ^a,b,d   Guo, Zhi Hong ^a   Geiger, Jonathan D ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF MANITOBA   (Canada)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer's disease; Amyloid peptide; Apoptosis; Excitotoxicity; Lipid peroxidation; Synapse

Indexed keywords

8 BROMO CYCLIC GMP; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; FERROUS ION; GLUCOSE; GLUTAMIC ACID;

ALZHEIMER DISEASE; AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; GLUCOSE TRANSPORT; NERVE CELL; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ALKALOIDS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT; CARBAZOLES; CEREBRAL CORTEX; CYCLIC GMP; ENZYME INHIBITORS; FEMALE; FERROUS COMPOUNDS; GLUCOSE; GLUTAMIC ACID; INDOLES; LIPID PEROXIDATION; NEURONS; NEUROTOXINS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SYNAPSES; SYNAPTOSOMES; TRITIUM;

ANIMALIA;

EID: 0344483869     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0730532.x     Document Type: Article

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