Defining the steps that lead to cancer: Replicative telomere erosion, aneuploidy and an epigenetic maturation arrest of tissue stem cells

Medical Hypotheses

Volumn 71, Issue 1, 2008, Pages 126-140

  Stindl, Reinhard ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Alpharm GesmbH ^*  (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CHROMOSOMAL INSTABILITY; CYTOGENETICS; DNA METHYLATION; DNA REPLICATION; EPIGENETICS; GENE AMPLIFICATION; GENE MUTATION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; LIVER CELL CARCINOMA; METASTASIS; PRIORITY JOURNAL; STEM CELL; TELOMERE;

ADULT STEM CELLS; AGING; ANEUPLOIDY; CELL DIFFERENTIATION; DRUG RESISTANCE, NEOPLASM; EPIGENESIS, GENETIC; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; MALE; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NEOPLASMS; NEOPLASTIC STEM CELLS; ONCOGENES; TELOMERE;

EID: 43949118802     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2008.01.010     Document Type: Article

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