메뉴 건너뛰기




Volumn 14, Issue 5, 1996, Pages

A functional screen in yeast for regulators and antagonizers of heterologous protein tyrosine kinases

Author keywords

Heterologous tyrosine kinases; Including receptor type tyrosine kinases; Which impair growth of s. Pombe. Tyrosine kinase, tyrosine phosphatase, src, csk, schizosaccharomyces pombe

Indexed keywords

EUKARYOTA; SCHIZOSACCHAROMYCES POMBE; FUNGI; SACCHAROMYCES; SACCHAROMYCES POMBE;

EID: 0029917331     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0596-600     Document Type: Article
Times cited : (28)

References (49)
  • 1
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Levitzki, A. and Gazit, A. 1995. Tyrosine kinase inhibition: an approach to drug development. Science 267:1782-1788.
    • (1995) Science , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 3
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks, S.J., Quinn, A.M., and Hunter, T. 1988. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241:42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.J.1    Quinn, A.M.2    Hunter, T.3
  • 4
    • 0028492201 scopus 로고
    • Protein tyrosine kinases, with emphasis on the Src family
    • Courtneidge, S.A. 1994. Protein tyrosine kinases, with emphasis on the Src family. Sem. in Cancer Biol. 5:239-246.
    • (1994) Sem. in Cancer Biol. , vol.5 , pp. 239-246
    • Courtneidge, S.A.1
  • 5
    • 0027267532 scopus 로고
    • Nonreceptor tyrosine protein kinases
    • Bolen, J.B. 1993. Nonreceptor tyrosine protein kinases. Oncogene 8:2025-2031.
    • (1993) Oncogene , vol.8 , pp. 2025-2031
    • Bolen, J.B.1
  • 6
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich, A. and Schlessinger. 1990. Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger2
  • 8
    • 0028170817 scopus 로고
    • Receptor protein-tyrosine kinases and their signal transduction pathways
    • van der Geer, P., Hunter, T., and Lindberg, R.A. 1994. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 10:251-337.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 251-337
    • Van der Geer, P.1    Hunter, T.2    Lindberg, R.A.3
  • 9
    • 0028958025 scopus 로고
    • Src family protein kinases and cellular signal transduction pathways
    • Erpel, T. and Courtneidge, S.A. 1995. Src family protein kinases and cellular signal transduction pathways. Curr. Biology 7:176-182.
    • (1995) Curr. Biology , vol.7 , pp. 176-182
    • Erpel, T.1    Courtneidge, S.A.2
  • 10
    • 0029278886 scopus 로고
    • Structure-function relationships in Src family and related protein tyrosine kinases
    • Superti-Furga, G. and Courtneidge, S.A. 1995. Structure-function relationships in Src family and related protein tyrosine kinases. Bioessays 17:321-330.
    • (1995) Bioessays , vol.17 , pp. 321-330
    • Superti-Furga, G.1    Courtneidge, S.A.2
  • 11
    • 0027300619 scopus 로고
    • The when and how of Src regulation
    • Cooper, J.A. and Howell, B. 1993. The when and how of Src regulation. Cell 73:1051-1054.
    • (1993) Cell , vol.73 , pp. 1051-1054
    • Cooper, J.A.1    Howell, B.2
  • 12
    • 0028983318 scopus 로고
    • Regulation of the Src protein tyrosine kinase
    • Superti-Furga, G. 1995. Regulation of the Src protein tyrosine kinase. FEBS Letters 369:62-66.
    • (1995) FEBS Letters , vol.369 , pp. 62-66
    • Superti-Furga, G.1
  • 13
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields, S. and Song, O. 1989. A novel genetic system to detect protein-protein interactions. Nature 340:245-246.
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.2
  • 14
    • 0028181873 scopus 로고
    • Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites
    • Ren, R., Ye, Z.-S., and Baltimore, D. 1994. Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites. Genes 8 Dev. 8:783-795.
    • (1994) Genes 8 Dev. , vol.8 , pp. 783-795
    • Ren, R.1    Ye, Z.-S.2    Baltimore, D.3
  • 15
    • 11944275667 scopus 로고
    • Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity
    • Dai, Z. and Pendergast, A.M. 1995. Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. Genes & Dev. 9:2596-2582.
    • (1995) Genes & Dev. , vol.9 , pp. 2596-12582
    • Dai, Z.1    Pendergast, A.M.2
  • 16
    • 0028844631 scopus 로고
    • Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity
    • Shi, Y, Ålin, K., and Goff, S.R 1995. Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity. Genes & Dev. 9:2583-2597.
    • (1995) Genes & Dev. , vol.9 , pp. 2583-2597
    • Shi, Y.1    Ålin, K.2    Goff, S.R.3
  • 17
    • 0028802599 scopus 로고
    • The yeast tribrid system: Genetic detection of trans-phosphorylated ITAM-SH2-interactions
    • Osborne, M.A., Dalton, S., and Kochan, J.P. 1995. The yeast tribrid system: genetic detection of trans-phosphorylated ITAM-SH2-interactions. Bio/Technology 13:1474-1478.
    • (1995) Bio/Technology , vol.13 , pp. 1474-1478
    • Osborne, M.A.1    Dalton, S.2    Kochan, J.P.3
  • 18
    • 0028848299 scopus 로고
    • The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development
    • Kinoshita, N., Minshull, J., and Kirschner, M.W. 1995. The identification of two novel ligands of the FGF receptor by a yeast screening method and their activity in Xenopus development. Cell 83:621-630.
    • (1995) Cell , vol.83 , pp. 621-630
    • Kinoshita, N.1    Minshull, J.2    Kirschner, M.W.3
  • 19
    • 0027182279 scopus 로고
    • Csk inhibition of Src activity requires both the SH2 and SH3 domains of Src
    • Superti-Furga, G., Fumagalli, S., Koegl, M., Courtneidge, S.A., and Draetta, G. 1993. Csk inhibition of Src activity requires both the SH2 and SH3 domains of Src. EMBO J. 12:2625-2634.
    • (1993) EMBO J. , vol.12 , pp. 2625-2634
    • Superti-Furga, G.1    Fumagalli, S.2    Koegl, M.3    Courtneidge, S.A.4    Draetta, G.5
  • 20
    • 0020663608 scopus 로고
    • The primary structure of the alcohol dehydrogenase gene from the fission yeast Schizsaccharomyces pombe
    • Russell, P.R. and Hall, B.D. 1983. The primary structure of the alcohol dehydrogenase gene from the fission yeast Schizsaccharomyces pombe. J. Biol. Chem. 258:143-149.
    • (1983) J. Biol. Chem. , vol.258 , pp. 143-149
    • Russell, P.R.1    Hall, B.D.2
  • 21
    • 0025298571 scopus 로고
    • nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine
    • Maundrell, K. 1990. nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine. J. Biol. Chem. 265:10857-10864.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10857-10864
    • Maundrell, K.1
  • 22
    • 0025861228 scopus 로고
    • Uptake of thiamine by Schizosaccharomyces pombe and its effects as a transcriptional regulator of thiamine sensitive genes
    • Tommasino, M. and Maundrell, K. 1991. Uptake of thiamine by Schizosaccharomyces pombe and its effects as a transcriptional regulator of thiamine sensitive genes. Curr. Genet. 20:63-66.
    • (1991) Curr. Genet. , vol.20 , pp. 63-66
    • Tommasino, M.1    Maundrell, K.2
  • 24
    • 0025940264 scopus 로고
    • Cyl encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src)
    • Partanen, J., Armstrong, E., Bergman, M., Mäkelä, T.P., Hirvonen, H., Huebner, K. et al. 1991. Cyl encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src). Oncogene 6:2013-2018.
    • (1991) Oncogene , vol.6 , pp. 2013-2018
    • Partanen, J.1    Armstrong, E.2    Bergman, M.3    Mäkelä, T.P.4    Hirvonen, H.5    Huebner, K.6
  • 25
    • 0029563574 scopus 로고
    • Structural requirements for the efficient regulation of the Src protein tyrosine kinase by Csk
    • Koegl, M., Courtneidge, S.A., and Superti-Furga, G. 1995. Structural requirements for the efficient regulation of the Src protein tyrosine kinase by Csk. Oncogene 11:2317-2329.
    • (1995) Oncogene , vol.11 , pp. 2317-2329
    • Koegl, M.1    Courtneidge, S.A.2    Superti-Furga, G.3
  • 26
    • 0026664593 scopus 로고
    • Differential expression of a novel murine nonreceptor protein tyrosine phosphatase during differentiation of p19 embryonal carcinoma cells
    • den Hertog, J., Pals, C.E.G.M., Jonk, L.J.C., and Kruijer, W. 1992. Differential expression of a novel murine nonreceptor protein tyrosine phosphatase during differentiation of p19 embryonal carcinoma cells. Biochem. Biophys. Res. Comm. 184:1241-1249.
    • (1992) Biochem. Biophys. Res. Comm. , vol.184 , pp. 1241-1249
    • Den Hertog, J.1    Pals, C.E.G.M.2    Jonk, L.J.C.3    Kruijer, W.4
  • 27
    • 0027102599 scopus 로고
    • Cloning and characterization of a human cDNA encoding a novel putative cytoplasmic protein tyrosine phosphatase
    • Takekawa, M., Itoh, F., Hinoda, Y., Arimura, Y., Totota, M., Sekiya, M. et al. 1992. Cloning and characterization of a human cDNA encoding a novel putative cytoplasmic protein tyrosine phosphatase. Biochem. Biophys. Res. Comm. 189:1223-1230.
    • (1992) Biochem. Biophys. Res. Comm. , vol.189 , pp. 1223-1230
    • Takekawa, M.1    Itoh, F.2    Hinoda, Y.3    Arimura, Y.4    Totota, M.5    Sekiya, M.6
  • 29
    • 0028040007 scopus 로고
    • Molecular cloning of a novel protein-tyrosine phosphatase containing a membrane-binding domain and GLGF repeats
    • Maekawa, K., Imagawa, N., Nagamatsu, M., and Harada, S. 1994. Molecular cloning of a novel protein-tyrosine phosphatase containing a membrane-binding domain and GLGF repeats. FEBS Letters 337:200-206.
    • (1994) FEBS Letters , vol.337 , pp. 200-206
    • Maekawa, K.1    Imagawa, N.2    Nagamatsu, M.3    Harada, S.4
  • 30
    • 0028003644 scopus 로고
    • Cloning and characterization of PTPL1, a protein tyrosine phosphatase with similarities to cytoskeletal-associated proteins
    • Saras, J., Claesson-Welsh, L., Heldin, C.-H., and Gonez, L.J. 1994. Cloning and characterization of PTPL1, a protein tyrosine phosphatase with similarities to cytoskeletal-associated proteins. J. Biol. Chem. 269:24082-24089.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24082-24089
    • Saras, J.1    Claesson-Welsh, L.2    Heldin, C.-H.3    Gonez, L.J.4
  • 31
    • 0028026907 scopus 로고
    • A novel protein-tyrosine phosphatase with homology to both the cytoskeletal proteins of the band 4.1 family and junction-associated guanylate kinases
    • Banville, D., Ahmad, S., Stocco, R., and Shen, S.H. 1994. A novel protein-tyrosine phosphatase with homology to both the cytoskeletal proteins of the band 4.1 family and junction-associated guanylate kinases. J. Biol. Chem. 269:22320-22327.
    • (1994) J. Biol. Chem. , vol.269 , pp. 22320-22327
    • Banville, D.1    Ahmad, S.2    Stocco, R.3    Shen, S.H.4
  • 33
    • 0023377484 scopus 로고
    • Characterization of avian and viral p60src proteins expressed in yeast
    • Kornbluth, S., Jove, R., and Hanafusa, H. 1987. Characterization of avian and viral p60src proteins expressed in yeast. Proc. Natl. Acad. Sci. USA 84:4455-4459.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 4455-4459
    • Kornbluth, S.1    Jove, R.2    Hanafusa, H.3
  • 34
    • 0027261372 scopus 로고
    • Suppression of c-Src activity by C-terminal Src kinase involves the c-Src SH2 and SH3 domains: Analysis with Saccharomyces cerevisiae
    • Murphy, S.M., Bergman, M., and Morgan, D.O. 1993. Suppression of c-Src activity by C-terminal Src kinase involves the c-Src SH2 and SH3 domains: analysis with Saccharomyces cerevisiae. Mol. Cell. Biol. 13:5290-5300.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5290-5300
    • Murphy, S.M.1    Bergman, M.2    Morgan, D.O.3
  • 35
    • 0027441494 scopus 로고
    • TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility
    • Basi, G., Schmid, E., and Maundrell, K. 1993. TATA box mutations in the Schizosaccharomyces pombe nmt1 promoter affect transcription efficiency but not the transcription start point or thiamine repressibility. Gene 123:131-136.
    • (1993) Gene , vol.123 , pp. 131-136
    • Basi, G.1    Schmid, E.2    Maundrell, K.3
  • 36
    • 0027185274 scopus 로고
    • Comparison of Schizosaccharomyces pombe expression systems
    • Forsburg, S.L. 1993. Comparison of Schizosaccharomyces pombe expression systems. Nucleic Acids Res. 21:2955-2956.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 2955-2956
    • Forsburg, S.L.1
  • 38
    • 0026355723 scopus 로고
    • CSK: A protein-tyrosine kinase involved in regulation of src family kinases
    • Okada, M., Nada, S., Yamanashi, Y., Yamamoto, T., and Nakagawa, H. 1991. CSK: a protein-tyrosine kinase involved in regulation of src family kinases. J. Biol. Chem. 266:24249-24252.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24249-24252
    • Okada, M.1    Nada, S.2    Yamanashi, Y.3    Yamamoto, T.4    Nakagawa, H.5
  • 39
    • 0026043267 scopus 로고
    • Identification of novel tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification
    • Yi, T., Cleveland, J.L., and Ihle, J.N. 1991. Identification of novel tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification. Blood 78:2222-2228.
    • (1991) Blood , vol.78 , pp. 2222-2228
    • Yi, T.1    Cleveland, J.L.2    Ihle, J.N.3
  • 40
    • 0028327357 scopus 로고
    • Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60 v-src expressed in the yeast Saccharomyces cerevisiae
    • Florio, M., Wilson, L.K., Trager, J.B., Thorner, J., and Martin, G.S. 1994. Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60 v-src expressed in the yeast Saccharomyces cerevisiae. Molec. Biol. Cell. 5:283-296.
    • (1994) Molec. Biol. Cell. , vol.5 , pp. 283-296
    • Florio, M.1    Wilson, L.K.2    Trager, J.B.3    Thorner, J.4    Martin, G.S.5
  • 41
    • 0029670421 scopus 로고    scopus 로고
    • Analysis of human c-Abl tyrosine kinase activity and regulation in S. pombe
    • In press
    • Walkenhorst, J., Goga, A., Witte, O.N., and Superti-Furga, G. 1996. Analysis of human c-Abl tyrosine kinase activity and regulation in S. pombe. Oncogene. In press.
    • (1996) Oncogene
    • Walkenhorst, J.1    Goga, A.2    Witte, O.N.3    Superti-Furga, G.4
  • 42
    • 0023722245 scopus 로고
    • c-src and a novel protein tyrosine kinase
    • c-src and a novel protein tyrosine kinase. J. Biochem. 104:297-305.
    • (1988) J. Biochem. , vol.104 , pp. 297-305
    • Okada, M.1    Nakagawa, H.2
  • 43
    • 0027534781 scopus 로고
    • Phosphorylation of Src mutants at Tyr 527 in fibroblasts does not correlate with in vitro phosphorylation by CSK
    • MacAuley, A., Okada, M., Nada, S., Nakagawa, H., and Cooper, J.A. 1993. Phosphorylation of Src mutants at Tyr 527 in fibroblasts does not correlate with in vitro phosphorylation by CSK. Oncogene 8;117-124.
    • (1993) Oncogene , vol.8 , pp. 117-124
    • MacAuley, A.1    Okada, M.2    Nada, S.3    Nakagawa, H.4    Cooper, J.A.5
  • 44
    • 0027390036 scopus 로고
    • Thiamine-repressible expression vectors pREP and pRIP for fission yeast
    • Maundrell, K. 1993. Thiamine-repressible expression vectors pREP and pRIP for fission yeast. Gene 123:127-130.
    • (1993) Gene , vol.123 , pp. 127-130
    • Maundrell, K.1
  • 45
    • 0023637186 scopus 로고
    • An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2
    • Seed, B. 1987. An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2. Nature 329:840-842.
    • (1987) Nature , vol.329 , pp. 840-842
    • Seed, B.1
  • 46
    • 0021016329 scopus 로고
    • A simple and very efficient method for generating cDNA libraries
    • Gubler, U. and Hoffmann, B.J. 1983. A simple and very efficient method for generating cDNA libraries. Gene 25:263-269.
    • (1983) Gene , vol.25 , pp. 263-269
    • Gubler, U.1    Hoffmann, B.J.2
  • 47
    • 0026698147 scopus 로고
    • Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CMS, and adult testis
    • Adams, B., Dörfler, P., Aguzzi, A., Kozmik, Z., Urbanek, R, Maurer-Fogy, I. et al. 1992. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CMS, and adult testis. Genes S Dev. 6:1589-1607.
    • (1992) Genes S Dev. , vol.6 , pp. 1589-1607
    • Adams, B.1    Dörfler, P.2    Aguzzi, A.3    Kozmik, Z.4    Urbanek, R.5    Maurer-Fogy, I.6
  • 48
    • 0026025891 scopus 로고
    • Molecular Genetic Analysis of Fission Yeast Schizosaccharomyces pombe
    • Guthrie, C. and Fink, G. (eds.)
    • Moreno, S., Klar, A., and Nurse, P. 1991. Molecular Genetic Analysis of Fission Yeast Schizosaccharomyces pombe, pp. 795-826 in Guide to Yeast Genetics and Molecular Biology, vol. 194. Guthrie, C. and Fink, G. (eds.).
    • (1991) Guide to Yeast Genetics and Molecular Biology , vol.194 , pp. 795-826
    • Moreno, S.1    Klar, A.2    Nurse, P.3
  • 49
    • 0025172811 scopus 로고
    • Association between the PDGF receptor and members of the src family of tyrosine kinases
    • Kypta, R.M., Goldberg, Y., Ulug, E.T., and Courtneidge, S.A. 1990. Association between the PDGF receptor and members of the src family of tyrosine kinases. Cell 62:481-492.
    • (1990) Cell , vol.62 , pp. 481-492
    • Kypta, R.M.1    Goldberg, Y.2    Ulug, E.T.3    Courtneidge, S.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.