The essence of total synthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 33, 2004, Pages 11929-11936

  Nicolaou, K C ^a   Snyder, Scott A ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

NATURAL PRODUCT; PENICILLIN G; PROGESTERONE; PROSTAGLANDIN F2 ALPHA; QUININE;

CHEMICAL STRUCTURE; DIELS ALDER REACTION; EXPERIMENT; ORGANIC CHEMISTRY; PRIORITY JOURNAL; REVIEW; SYNTHESIS;

BIOLOGICAL PRODUCTS; CHEMISTRY, ORGANIC; CHEMISTRY, PHARMACEUTICAL; HISTORY, 20TH CENTURY; MOLECULAR STRUCTURE;

BETULACEAE; CINCHONA PUBESCENS;

EID: 4344703950     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0403799101     Document Type: Review

References (57)

1. Nicolaou, K. C. & Sorensen, E. J. (1996) Classics in Total Synthesis: Targets, Strategies, Methods (VCH, Weinheim, Germany), p. 799.
2. Nicolaou, K. C. & Snyder, S. A. (2003) Classics in Total Synthesis II: More Targets, Strategies, Methods (Wiley-VCH, Weinheim, Germany), p. 639.
3. Nicolaou, K. C., Vourloumis, D., Winssinger, N. & Baran, P. S. (2000) Angew. Chem. Int. Ed. 39, 44-122.
4. Garfield, S. (2000) Mauve (Faber & Faber, London), p. 224.
5. Djerassi, C. (1990) Steroids Made It Possible (American Chemical Society, Washington. D.C.), p. 205.
6. Sheehan, J. C. (1984) The Enchanted Ring: The Untold Story of Penicillin (MIT Press, Cambridge), p. 224.
7. Corey, E. J. & Chen, X.-M. (1989) The Logic of Chemical Synthesis (Wiley, New York), p. 436.
8. Götschi, E., Hunkeler, W., Wild, H.-J., Schneider, P., Fuhrer, W., Gleason, J. & Eschenmosher, A. (1973) Angew. Chem. Int. Ed. 12, 910-912.
9. Benfey, O. T. & Morris, P. J. T. (2001) Robert Burns Woodward: Artist and Architect in the World of Molecules (Chemical Heritage Foundation, Philadelphia), p. 470.
10. Nicolaou, K. C., Montagnon, T. & Snyder, S. A. (2003) Chem. Commun., 551-564.
11. Nicolaou, K. C., Vassilikogiannakis, G., Simonsen, K. B., Baran, P. S., Zhong, Y.-L., Vidali, V. P., Pitsinos, E. N. & Couladouros, E. A. (2000) J. Am. Chem. Soc. 122, 3071-3079.
12. Barnes-Seeman, D. & Corey, E. J. (1999) Org. Lett. 1, 1503-1504.
13. Nicolaou, K. C. (1996) Angew. Chem. Int. Ed. 35, 589-607.
14. Nicolaou, K. C., Hwang, C.-K., Duggan, M. E., Nugiel, D. A., Abe, Y., Bal Reddy, K., DeFrees, S. A., Reddy, D. R., Awartani, R. A., Conley, S. R., et al. (1995) J. Am. Chem. Soc. 117, 10227-10238.
15. Nicolaou, K. C., Theodorakis, E. A., Rutjes, F. P. J. T., Sato, M., Tiebes, J., Xiao, X.-Y., Hwang, C.-K., Duggan, M. E., Yang, Z., Couladouros, E. A., et al. (1995) J. Am. Chem. Soc. 117, 10239-10251.
16. Nicolaou, K. C., Rutjes, F. P. J. T., Theodorakis, E. A., Tiebes, J., Sato, M. & Untersteller, E. (1995) J. Am. Chem. Soc. 117, 10252-10263.
17. Nicolaou, K. C., Bunnage, M. E., McGarry, D. G., Shi, S., Somers, P. K., Wallace, P. A., Chu, X.-J., Agrios, K. A., Gunzner, J. L. & Yang, Z. (1999) Chem. Eur. J. 5, 599-617.
18. Nicolaou, K. C., Wallace, P. A., Shi, S., Ouellette, M. A., Bunnage, M. E., Gunzner, J. L., Argrios, K. A., Shi, G.-Q. & Yang, Z. (1999) Chem. Eur. J. 5, 618-627.
19. Nicolaou, K. C., Shi, G.-Q., Gunzner, J. L., Gärtner, P., Wallace, P. A., Ouellette, M. A., Shi, S., Bunnage, M. E., Agrios, K. A., Veale, C. A., et al. (1999) Chem. Eur. J. 5, 628-645.
20. Nicolaou, K. C., Gunzner, J. L., Shi, G.-Q., Agrios, K. A., Gärtner, P. & Yang, Z. (1999) Chem. Eur. J. 5, 646-658.
21. Nicolaou, K. C. & Baran, P. S. (2002) Angew. Chem. Int. Ed. 41, 2678-2720.
22. Nicolaou, K. C., Jung, J., Yoon, W. H., Fong, K. C., Choi, H.-S., He, Y., Zhong, Y.-L. & Baran, P. S. (2002) J. Am. Chem. Soc. 124, 2183-2189.
23. Nicolaou, K. C., Baran, P. S., Zhong, Y.-L., Fong, K. C. & Choi, H.-S. (2002) J. Am. Chem. Soc. 124, 2190-2201.
24. Nicolaou, K. C., Zhong, Y.-L., Baran, P. S., Jung, J., Choi, H.-S. & Yoon, W. H. (2002) J. Am. Chem. Soc. 124, 2202-2211.
25. Nicolaou, K. C., Mathison, C. J. N. & Montagnon, T. (2004) J. Am. Chem. Soc. 126, 5192-5201.
26. Li, J., Burgett, A. W. G., Esser, L., Amerzcua, C. & Harran, P. G. (2001) Angew. Chem. Int. Ed. 40, 4770-4773.
27. Nicolaou, K. C., Snyder, S. A., Simonsen, K. B. & Koumbis, A. E. (2000) Angew. Chem. Int. Ed. 39, 3473-3478.
28. Nicolaou, K. C., Snyder, S. A., Bigot, A. & Pfefferkorn, J. A. (2000) Angew. Chem. Int. Ed. 39, 1093-1096.
29. Li, J., Jeong, S., Esser, L. & Harran, P. G. (2001) Angew. Chem. Int. Ed. 40, 4765-4770.
30. Nicolaou, K. C., Bella, M., Chen, D. Y.-K., Huang, X., Ling, T. & Snyder, S. A. (2002) Angew. Chem. Int. Ed. 41, 3495-3499.
31. Nicolaou, K. C., Bheema Rao, P., Hao, J., Reddy, M. V., Rassias, G., Huang, X., Chen, D. Y.-K. & Snyder, S. A. (2003) Angew. Chem. Int. Ed. 42, 1753-1758.
32. Nicolaou, K. C. (1993)Angew. Chem. Int. Ed. 32, 1377-1385.
33. Groneberg, R. D., Miyazaki, T., Stylianides, N. A., Schulze, T. J., Stahl, W., Schreiner, E. P., Suzuki, T., Iwabuchi, Y., Smith, A. L. & Nicolaou, K. C. (1993) J. Am. Chem. Soc. 115, 7593-7611.
34. Smith, A. L., Pitsinos, E., Hwang, C.-K., Mizuno, Y., Saimoto, H., Scarlato, G. R., Suzuki, T. & Nicolaou, K. C. (1993) J. Am. Chem. Soc. 115, 7612-7624.
35. Nicolaou, K. C., Hummel, C. W., Nakada, M., Shibayama, K., Pitsinos, E. N., Saimoto, H., Mizuno, Y., Baldenius, K.-U. & Smith, A. L. (1993) J. Am. Chem. Soc. 115, 7625-7635.
36. Nicolaou, K. C. & Smith, A. L. (1992) Acc. Chem. Res. 25, 497-503.
37. Nicolaou, K. C., Dai, W.-M. & Guy, R. K. (1994) Angew. Chem. Int. Ed. 33, 15-44.
38. Nicolaou, K. C., Snyder, S. A., Montagnon, T. & Vassilikogiannakis, G. E. (2002) Angew. Chem. Int. Ed. 41, 1668-1698.
39. Nicolaou, K. C., Nantermet, P. G., Ueno, H., Guy, R. K., Couladouros, E. A. & Sorensen, E. J. (1995) J. Am. Chem. Soc. 117, 624-633.
40. Nicolaou, K. C., Liu, J.-J., Yang, Z., Ueno, H. Sorensen, E. J., Claiborne, C. F., Guy, R. K., Hwang, C.-K., Nakada, M. & Nantermet, P. G. (1995) J. Am. Chem. Soc. 117, 634-644.
41. Nicolaou, K. C., Yang, Z., Liu, J.-J., Nantermet, P. G., Claiborne, C. F., Renaud, J., Guy, R. K. & Shibayama, K. (1995) J. Am. Chem. Soc. 117, 645-652.
42. Nicolaou, K. C., Ueno, H., Liu, J.-J., Nantermet, P. G., Yang, Z., Renaud, J., Paulvannan, K. & Chadha, R. (1995) J. Am. Chem. Soc. 117, 653-659.
43. Nicolaou, K. C., Guy, R. K., Pitsinos, E. N. & Wrasidlo, W. (1994) Angew. Chem. Int. Ed. 33, 1583-1587.
44. Nicolaou, K. C., Boddy, C. N. C., Bräse, S. & Winssinger, N. (1999) Angew. Chem. Int. Ed. 38, 2096-2152.
45. Nicolaou, K. C., Boddy, C. N. C., Natarajan, S., Yue, T.-Y., Li, H., Bräse, S. & Ramanjulu, J. M. (1997) J. Am. Chem. Soc. 119, 3421-3422.
46. Nicolaou, K. C., Li, H., Boddy, C. N. C., Ramanjulu, J. M., Yue, T.-Y., Natarajan, S., Chu, X.-J., Bräse, S. & Rübsam, F. (1999) Chem. Eur. J. 5, 2584-2601.
47. Nicolaou, K. C., Boddy, C. N. C., Li, H., Koumbis, A. E., Hughes, R., Natarajan, S., Jain, N. F., Ramanjulu, J. M. & Bräse, S. (1999) Chem. Eur. J. 5, 2602-2621.
48. Nicolaou, K. C., Koumbis, A. E., Takayanagi, M., Natarajan, S., Jain, N. F., Bando, T., Li, H. & Hughes, R. (1999) Chem. Eur. J. 5, 2622-2647.
49. Nicolaou, K. C., Mitchell, H. J., Jain, N. F., Hughes, R., Winssinger, N., Natarajan, S. & Koumbis, A. E. (1999) Chem. Eur. J. 5, 2648-2667.
50. Trnka, T. M. & Grubbs, R. H. (2001) Acc. Chem. Res. 34, 18-29.
51. Nicolaou, K. C., Hughes, R., Cho, S. Y., Winssinger, N., Labischinski, H. & Endermann, R. (2001) Chem. Eur. J. 7, 3824-3843.
52. Nicolaou, K. C., Roschanger, F. & Vourloumis, D. (1998) Angew. Chem. Int. Ed. 37, 2014-2045.
53. Nicolaou, K. C., Ritzén, A. & Namoto, K. (2001) Chem. Commun. 1523-1535.
54. Nicolaou, K. C., Winssinger, N., Pastor, J., Ninkovic, S., Sarabia, F., Vourloumis, D., Yang, Z., Li, T., Giannakakou, P. & Hamel, E. (1997) Nature 387, 268-272.
55. Boger, D. L., Desharnais, J. & Capps, K. (2003) Angew. Chem. Int. Ed. 42, 4138-4176.
56. Nicolaou, K. C., Xiao, X.-Y., Parandoosh, Z., Senyei, A. & Nova, M. P. (1995) Angew. Chem. Int. Ed. 34, 2289-2291.
57. Nicolaou, K. C. (2003) Tetrahedron 59, 6683-6738.