The catalytic mechanism of endoplasmic reticulum signal peptidase appears to be distinct from most eubacterial signal peptidases

Journal of Biological Chemistry

Volumn 274, Issue 17, 1999, Pages 11519-11525

  VanValkenburgh, Clint ^a   Chen, Xuemin ^a   Mullins, Chris ^a,b   Fang, Hong ^a   Green, Neil ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SIGNAL PEPTIDASE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; EUBACTERIUM; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIA; BASE SEQUENCE; CATALYSIS; DNA PRIMERS; ENDOPLASMIC RETICULUM; FUNGAL PROTEINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES;

EID: 0033597137     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.17.11519     Document Type: Article

References (39)

1. von Heijne, G. (1983) Eur. J. Biochem. 133, 17-21
2. Dalbey, R. E., Lively, M. O., Bron, S., and van Dijl, J. M. (1997) Protein Sci. 6, 1129-1138
3. Talmadge, K., Kaufman, J., and Gilbert, W. (1980) Proc. Natl. Acad. Sci. U. S. A. 77, 3988-3992
4. Lingappa, V. R., Chaidez, J., Yost, C. S., and Hedgpeth, J. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 456-460
5. Black, M. T. (1993) J. Bacteriol. 175, 4957-4961
6. Paetzel, M., Strynadka, N. C. J., Tschantz, W. R., Casareno, R., Bullinger, P. R., and Dalbey, R. E. (1997) J. Biol. Chem. 272, 9994-10003
7. Sung, M., and Dalbey, R. E. (1992) J. Biol. Chem. 267, 13154-13159
8. Tschantz, W. R, Sung, M., Delgado-Partin, V. M., and Dalbey, R. E. (1993) J. Biol. Chem. 268, 27349-27354
9. van Dijl, J. M., de Jong, A., Venema, G., and Bron, S. (1995) J. Biol. Chem. 270, 3611-3618
10. Peat, T. S., Frank, E. G., McDonald, J. P., Levine, A. S., Woodgate, R., and Hendrickson, W. A. (1996) Nature 380, 727-730
11. Slilaty, S. N., and Little, J. W. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 3987-3991
12. Nunnari, J., Fox, T. D., and Walter, P. (1993) Science 262, 1997-2004
13. Paetzel, M., Dalbey, R. E., and Strynadka, N. C. J. (1998) Nature 396, 186-190
14. Tjalsma, H., Bolhuis, A., van Roosmalen, M. L., Wiegert, T., Schumann, W., Broekhuizen, C. P., Quax, W. J., Venema, G., Bron, S., and van Dijl, J. M. (1998) Genes Dev. 12, 2318-2331
15. Tjalsma, H., Noback, M. A., Bron, S., Venema, G., Yamane, K., and van Dijl, J. M. (1997) J. Biol. Chem. 272, 25983-25992
16. Dalbey, R. E., and von Heijne, G. (1992) Trends Biochem. Sci. 17, 474-478
17. van Dijl, J. M., de Jong, A., Vehmaanpera, J., Venema, G., and Bron, S. (1992) EMBO J. 11, 2819-2828
18. Bohni, P. C., Deshaies, R. J., and Schekman, R. W. (1988) J. Cell Biol. 106, 1035-1042
19. Fang, H., Mullins, C., and Green, N. (1997) J. Biol. Chem. 272, 13152-13158
20. Fang, H., Panzner, S., Mullins, C., Hartmann, E., and Green, N. (1996) J. Biol. Chem. 271, 16460-16465
21. Meyer, H-A., and Hartmann, E. (1997) J. Biol. Chem. 272, 13159-13164
22. Mullins, C., Meyer, H-A., Hartmann, E., Green, N., and Fang, H. (1996) J. Biol. Chem. 271, 29094-29099
23. Mullins, C., Lu, Y., Campbell, A., Fang, H., and Green, N. (1995) J. Biol. Chem. 270, 17139-17147
24. Berben, G., Dumont, J., Gilliquet, V., Bolle, P.-A., and Hilger, F. (1991) Yeast 7, 475-477
25. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Scidman, J. G., Smith, J. A., and Strahl, K. (eds) (1987) in Current Protocols in Molecular Biology, Vol. 2, pp. 13.0.1-13.14.17, John Wiley & Sons, Inc., New York
26. Green, N., and Walter, P. (1992) Mol. Cell. Biol. 12, 276-282
27. Hansen, W., Garcia, P. D., and Walter, P. (1986) Cell 46, 397-406
28. Sanderson, C. M., and Meyer, D. I. (1991) J. Biol. Chem. 266, 13423-13430
29. Wilson, I. A., Niman, H. L., Houghten, R. A., Cherenson, A. R., Connolly, M. L., and Lerner, R. A. (1984) Cell 37, 767-778
30. Sikorski, R. S., and Hieter, P. (1989) Genetics 122, 19-27
31. Bennetzen, J. L., and Hall, B. D. (1982) J. Biol. Chem. 257, 3018-3025
32. Christianson, T. W., Sikorski, R. S., Dante, M., Shero, J. H., and Hieter, P. (1992) Gene (Amst.) 110, 119-122
33. Hopp, T. P., Prickett, K. S., Price, V. L., Libby, R. T., March, C. J., Cerretti, D. P., Urdal, D. L., and Conlon, P. J. (1988) Biotechnology 6, 1204-1210
34. Shelness, G. S., and Blobel, G. (1990) J. Biol. Chem. 265, 9512-9519
35. Sikorski, R. S., and Boeke, J. D. (1991) Methods Enzymol. 194, 302-318
36. Boeke, J. D., Trueheart, J., Natsoulis, G., and Fink, G. R. (1987) Methods Enzymol. 154, 164-175
37. Rose, M. D., Misra, L. M., and Vogel, J. P. (1989) Cell 57, 1211-1221
38. Carter, P., and Wells, J. A. (1988) Nature 332, 564-568
39. Wei, Y., Schottel, J. L., Derewenda, U., Swenson, L., Patkar, S., and Derewenda, Z. S. (1995) Nat. Struct. Biol. 2, 218-223