메뉴 건너뛰기




Volumn 615, Issue , 2008, Pages 251-260

Targeting proteasomes as therapy in multiple myeloma

Author keywords

Apoptosis; Drug resistance; Myeloma; Proteasomes

Indexed keywords

2 CYANO 3,12 DIOXOOLEANA 1,9 DIEN 28 OIC ACID; 6 CHLORO 8 NICOTINAMIDO BETA CARBOLINE; BORTEZOMIB; DEXAMETHASONE; DOXORUBICIN; HEAT SHOCK PROTEIN 90 INHIBITOR; HISTONE DEACETYLASE INHIBITOR; IMIDAZOLE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LENALIDOMIDE; MELPHALAN; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; MITOXANTRONE; PROTEASOME; SALINOSPORAMIDE A; TANESPIMYCIN; TUBACIN; UBIQUITIN; UNCLASSIFIED DRUG; PROTEINASE INHIBITOR;

EID: 43249127114     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4020-6554-5_12     Document Type: Review
Times cited : (45)

References (30)
  • 1
    • 0036680037 scopus 로고    scopus 로고
    • Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer
    • Adams, J. (2002). Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer. Curr Opin Chem Biol 6, 493-500.
    • (2002) Curr Opin Chem Biol , vol.6 , pp. 493-500
    • Adams, J.1
  • 2
    • 2342613652 scopus 로고    scopus 로고
    • The proteasome: A suitable antineoplastic target
    • Adams, J. (2004). The proteasome: a suitable antineoplastic target. Nat Rev Cancer 4, 349-360.
    • (2004) Nat Rev Cancer , vol.4 , pp. 349-360
    • Adams, J.1
  • 4
    • 0042167462 scopus 로고    scopus 로고
    • Mechanisms of cell death and survival in multiple myeloma (MM): Therapeutic implications
    • Chauhan, D. and Anderson, K. C. (2003). Mechanisms of cell death and survival in multiple myeloma (MM): Therapeutic implications. Apoptosis 8, 337-343.
    • (2003) Apoptosis , vol.8 , pp. 337-343
    • Chauhan, D.1    Anderson, K.C.2
  • 5
    • 0141953292 scopus 로고    scopus 로고
    • Blockade of Hsp27 overcomes Bortezomib/proteasome inhibitor PS-341 resistance in lymphoma cells
    • Chauhan, D., Li, G., Shringarpure, R., Podar, K., Ohtake, Y., Hideshima, T. and Anderson, K. C. (2003). Blockade of Hsp27 overcomes Bortezomib/proteasome inhibitor PS-341 resistance in lymphoma cells. Cancer Res 63, 6174-6177.
    • (2003) Cancer Res , vol.63 , pp. 6174-6177
    • Chauhan, D.1    Li, G.2    Shringarpure, R.3    Podar, K.4    Ohtake, Y.5    Hideshima, T.6    Anderson, K.C.7
  • 6
    • 27644562277 scopus 로고    scopus 로고
    • A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib
    • Chauhan, D., Catley, L., Li, G., Podar, K., Hideshima, T., Velankar, M., Mitsiades, C., Mitsiades, N., Yasui, H., Letai, A., et al. (2005a). A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib. Cancer Cell 8, 407-419.
    • (2005) Cancer Cell , vol.8 , pp. 407-419
    • Chauhan, D.1    Catley, L.2    Li, G.3    Podar, K.4    Hideshima, T.5    Velankar, M.6    Mitsiades, C.7    Mitsiades, N.8    Yasui, H.9    Letai, A.10
  • 7
    • 13844320703 scopus 로고    scopus 로고
    • Proteasome inhibition in multiple myeloma: Therapeutic implication
    • Chauhan, D., Hideshima, T., and Anderson, K. C. (2005b). Proteasome inhibition in multiple myeloma: therapeutic implication. Annu Rev Pharmacol Toxicol 45, 465-476.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 465-476
    • Chauhan, D.1    Hideshima, T.2    Anderson, K.C.3
  • 8
    • 33745728140 scopus 로고    scopus 로고
    • Comparative selectivity and specificity of the proteasome inhibitor BzLLLCOCHO, PS-341, and MG-132
    • Crawford, L., Walker, B., Ovaa, H., Chauhan, D., Anderson, K., Morris, T., and Irvine, T. (2006). Comparative selectivity and specificity of the proteasome inhibitor BzLLLCOCHO, PS-341, and MG-132. Cancer Res 66, 6379-6386.
    • (2006) Cancer Res , vol.66 , pp. 6379-6386
    • Crawford, L.1    Walker, B.2    Ovaa, H.3    Chauhan, D.4    Anderson, K.5    Morris, T.6    Irvine, T.7
  • 9
    • 0035328584 scopus 로고    scopus 로고
    • Cusack, J. C., Jr., Liu, R., Houston, M., Abendroth, K., Elliott, P. J., Adams, J., and Baldwin, A. S., Jr. (2001). Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. Cancer Res 61, 3535-3540.
    • Cusack, J. C., Jr., Liu, R., Houston, M., Abendroth, K., Elliott, P. J., Adams, J., and Baldwin, A. S., Jr. (2001). Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. Cancer Res 61, 3535-3540.
  • 10
    • 0037455147 scopus 로고    scopus 로고
    • Salinosporamide A: A highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora
    • Feling, R. H., Buchanan, G. O., Mincer, T. J., Kauffman, C. A., Jensen, P. R., and Fenical, W. (2003). Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora. Angew Chem Int Ed Engl 42, 355-357.
    • (2003) Angew Chem Int Ed Engl , vol.42 , pp. 355-357
    • Feling, R.H.1    Buchanan, G.O.2    Mincer, T.J.3    Kauffman, C.A.4    Jensen, P.R.5    Fenical, W.6
  • 11
    • 7644242953 scopus 로고    scopus 로고
    • Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells
    • Fribley, A., Zeng, Q., and Wang, C. Y. (2004). Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Mol Cell Biol 24, 9695-9704.
    • (2004) Mol Cell Biol , vol.24 , pp. 9695-9704
    • Fribley, A.1    Zeng, Q.2    Wang, C.Y.3
  • 12
    • 0036104603 scopus 로고    scopus 로고
    • Not just research tools - proteasome inhibitors offer therapeutic promise
    • Goldberg, A. L. and Rock, K. (2002). Not just research tools - proteasome inhibitors offer therapeutic promise. Nat Med 8, 338-340.
    • (2002) Nat Med , vol.8 , pp. 338-340
    • Goldberg, A.L.1    Rock, K.2
  • 13
    • 33646137808 scopus 로고    scopus 로고
    • Crystal structures of salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of betalactone ring opening and a mechanism for irreversible binding
    • Groll, M., Huber, R., and Potts, B. C. (2006). Crystal structures of salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of betalactone ring opening and a mechanism for irreversible binding. J Am Chem Soc 128, 5136-5141.
    • (2006) J Am Chem Soc , vol.128 , pp. 5136-5141
    • Groll, M.1    Huber, R.2    Potts, B.C.3
  • 14
    • 0037096221 scopus 로고    scopus 로고
    • NF-kappa B: Arresting a major culprit in cancer
    • Haefner, B. (2002). NF-kappa B: arresting a major culprit in cancer. Drug Discov Today 7, 653-663.
    • (2002) Drug Discov Today , vol.7 , pp. 653-663
    • Haefner, B.1
  • 15
    • 24944514626 scopus 로고    scopus 로고
    • Proteasome inhibition with bortezomib (PS-341): A phase I study with pharmacodynamic end points using a day 1 and day 4 schedule in a 14-day cycle
    • Hamilton, A. L., Eder, J. P., Pavlick, A. C., Clark, J. W., Liebes, L., Garcia-Carbonero, R., Chachoua, A., Ryan, D. P., Soma, V., Farrell, K., et al. (2005). Proteasome inhibition with bortezomib (PS-341): a phase I study with pharmacodynamic end points using a day 1 and day 4 schedule in a 14-day cycle. J Clin Oncol 23, 6107-6116.
    • (2005) J Clin Oncol , vol.23 , pp. 6107-6116
    • Hamilton, A.L.1    Eder, J.P.2    Pavlick, A.C.3    Clark, J.W.4    Liebes, L.5    Garcia-Carbonero, R.6    Chachoua, A.7    Ryan, D.P.8    Soma, V.9    Farrell, K.10
  • 18
    • 20844435806 scopus 로고    scopus 로고
    • Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma
    • Hideshima, T., Bradner, J. E., Wong, J., Chauhan, D., Richardson, P., Schreiber, S. L. and Anderson, K. C. (2005). Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma. Proc Natl Acad Sci USA 102, 8567-8572.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8567-8572
    • Hideshima, T.1    Bradner, J.E.2    Wong, J.3    Chauhan, D.4    Richardson, P.5    Schreiber, S.L.6    Anderson, K.C.7
  • 19
    • 33646841837 scopus 로고    scopus 로고
    • Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate
    • Kisselev, A. F., Callard, A., and Goldberg, A. L. (2006). Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate. J Biol Chem 281, 8582-8590.
    • (2006) J Biol Chem , vol.281 , pp. 8582-8590
    • Kisselev, A.F.1    Callard, A.2    Goldberg, A.L.3
  • 20
    • 18144431710 scopus 로고    scopus 로고
    • Mitochondrial-mediated disregulation of Ca2+ is a critical determinant of Velcade (PS-341/ bortezomib) cytotoxicity in myeloma cell lines
    • Landowski, T. H., Megli, C. J., Nullmeyer, K. D., Lynch, R. M., and Dorr, R. T. (2005). Mitochondrial-mediated disregulation of Ca2+ is a critical determinant of Velcade (PS-341/ bortezomib) cytotoxicity in myeloma cell lines. Cancer Res 65, 3828-3836.
    • (2005) Cancer Res , vol.65 , pp. 3828-3836
    • Landowski, T.H.1    Megli, C.J.2    Nullmeyer, K.D.3    Lynch, R.M.4    Dorr, R.T.5
  • 24
    • 0037443551 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
    • Mitsiades, N., Mitsiades, C. S., Richardson, P. G., Poulaki, V., Tai, Y. T., Chauhan, D., Fanourakis, G., Gu, X., Bailey, C., Joseph, M., et al. (2003). The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101, 2377-2380.
    • (2003) Blood , vol.101 , pp. 2377-2380
    • Mitsiades, N.1    Mitsiades, C.S.2    Richardson, P.G.3    Poulaki, V.4    Tai, Y.T.5    Chauhan, D.6    Fanourakis, G.7    Gu, X.8    Bailey, C.9    Joseph, M.10
  • 25
    • 23844481790 scopus 로고    scopus 로고
    • Caspase-12 and caspase-4 are not required for caspasedependent endoplasmic reticulum stress-induced apoptosis
    • Obeng, E. A. and Boise, L. H. (2005). Caspase-12 and caspase-4 are not required for caspasedependent endoplasmic reticulum stress-induced apoptosis. J Biol Chem 280, 29578-29587.
    • (2005) J Biol Chem , vol.280 , pp. 29578-29587
    • Obeng, E.A.1    Boise, L.H.2
  • 26
    • 0035818445 scopus 로고    scopus 로고
    • Redundancy of mammalian proteasome beta subunit function during endoplasmic reticulum associated degradation
    • Oberdorf, J., Carlson, E. J., and Skach, W. R. (2001). Redundancy of mammalian proteasome beta subunit function during endoplasmic reticulum associated degradation. Biochemistry 40, 13397-13405.
    • (2001) Biochemistry , vol.40 , pp. 13397-13405
    • Oberdorf, J.1    Carlson, E.J.2    Skach, W.R.3
  • 27
    • 0842303313 scopus 로고    scopus 로고
    • Back to the future with ubiquitin
    • Pickart, C. M. (2004). Back to the future with ubiquitin. Cell 116, 181-190.
    • (2004) Cell , vol.116 , pp. 181-190
    • Pickart, C.M.1
  • 28
    • 3142570867 scopus 로고    scopus 로고
    • A review of the proteasome inhibitor bortezomib in multiple myeloma
    • Richardson, P. G. (2004). A review of the proteasome inhibitor bortezomib in multiple myeloma. Expert Opin Pharmacother 5, 1321-1331.
    • (2004) Expert Opin Pharmacother , vol.5 , pp. 1321-1331
    • Richardson, P.G.1
  • 30
    • 33144469102 scopus 로고    scopus 로고
    • The proteasome and proteasome inhibitors in cancer therapy
    • Voorhees, P. M. and Orlowski, R. Z. (2006). The proteasome and proteasome inhibitors in cancer therapy. Annu Rev Pharmacol Toxicol 46, 189-213.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 189-213
    • Voorhees, P.M.1    Orlowski, R.Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.