메뉴 건너뛰기




Volumn 658, Issue 3, 2008, Pages 172-183

Nuclear architecture, chromosome domains and genetic damage

Author keywords

Chromatin dynamics; Chromosomal aberrations; Chromosome domains; Genetic damage; Nuclear architecture

Indexed keywords

CLASTOGEN; DEOXYRIBONUCLEASE I; DNA; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; DSBA PROTEIN; HISTONE H2A; HISTONE H2AX; HISTONE H2AZ; HISTONE H4; HYDROXYUREA; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MESSENGER RNA; RIBOSOME RNA; RNA POLYMERASE;

EID: 43149091457     PISSN: 13835742     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrrev.2007.08.005     Document Type: Review
Times cited : (36)

References (65)
  • 1
    • 0042767995 scopus 로고    scopus 로고
    • The dynamics of chromosome organization and gene regulation
    • Spector D.L. The dynamics of chromosome organization and gene regulation. Annu. Rev. Biochem. 72 (2003) 573-608
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 573-608
    • Spector, D.L.1
  • 2
    • 0035839002 scopus 로고    scopus 로고
    • Coupled transcription and translation within nuclei of mammalian cells
    • Iborra F.J., Jackson D.A., and Cook P.R. Coupled transcription and translation within nuclei of mammalian cells. Science 293 (2001) 1139-1142
    • (2001) Science , vol.293 , pp. 1139-1142
    • Iborra, F.J.1    Jackson, D.A.2    Cook, P.R.3
  • 5
    • 0033553877 scopus 로고    scopus 로고
    • Differences in the localization and morphology of chromosomes in the human nucleus
    • Croft J.A., Bridger J.M., Boyle S., Perry P., Teague P., and Bickmore W.A. Differences in the localization and morphology of chromosomes in the human nucleus. J. Cell Biol. 145 (1999) 1119-1131
    • (1999) J. Cell Biol. , vol.145 , pp. 1119-1131
    • Croft, J.A.1    Bridger, J.M.2    Boyle, S.3    Perry, P.4    Teague, P.5    Bickmore, W.A.6
  • 6
    • 0037173418 scopus 로고    scopus 로고
    • Non-random radial arrangements of interphase chromosome territories: evolutionary considerations and functional implications
    • Tanabe H., Habermann F.A., Solovei I., Cremer M., and Cremer T. Non-random radial arrangements of interphase chromosome territories: evolutionary considerations and functional implications. Mutat. Res. 504 (2002) 37-45
    • (2002) Mutat. Res. , vol.504 , pp. 37-45
    • Tanabe, H.1    Habermann, F.A.2    Solovei, I.3    Cremer, M.4    Cremer, T.5
  • 8
    • 0033588973 scopus 로고    scopus 로고
    • Nuclear organization of mammalian genomes: polar chromosome territories build up functionally distinct higher order compartments
    • Sadoni N., Langer S., Fauth C., Bernardi G., Cremer T., Turner B.M., and Zink D. Nuclear organization of mammalian genomes: polar chromosome territories build up functionally distinct higher order compartments. J. Cell Biol. 146 (1999) 1211-1226
    • (1999) J. Cell Biol. , vol.146 , pp. 1211-1226
    • Sadoni, N.1    Langer, S.2    Fauth, C.3    Bernardi, G.4    Cremer, T.5    Turner, B.M.6    Zink, D.7
  • 9
    • 33845986339 scopus 로고    scopus 로고
    • Spatial genome organization in the formation of chromosomal translocations
    • Meaburn K.J., Misteli T., and Soutoglou E. Spatial genome organization in the formation of chromosomal translocations. Semin. Cancer Biol. 17 (2007) 80-90
    • (2007) Semin. Cancer Biol. , vol.17 , pp. 80-90
    • Meaburn, K.J.1    Misteli, T.2    Soutoglou, E.3
  • 11
    • 0035316574 scopus 로고    scopus 로고
    • Chromosome territories, nuclear architecture, and gene regulation in mammalian cells
    • Cremer T., and Cremer C. Chromosome territories, nuclear architecture, and gene regulation in mammalian cells. Nat. Rev. Genet. 2 (2001) 292-301
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 292-301
    • Cremer, T.1    Cremer, C.2
  • 12
    • 0033523776 scopus 로고    scopus 로고
    • Spatial relationships between transcription sites and chromosome territories
    • Verschure P.J., van der Kraan I., Manders E.M., and van Driel R. Spatial relationships between transcription sites and chromosome territories. J. Cell Biol. 147 (1999) 13-24
    • (1999) J. Cell Biol. , vol.147 , pp. 13-24
    • Verschure, P.J.1    van der Kraan, I.2    Manders, E.M.3    van Driel, R.4
  • 13
    • 34250777112 scopus 로고    scopus 로고
    • The nuclear envelope and transcriptional control
    • Akhtar A., and Gasser S.M. The nuclear envelope and transcriptional control. Nat. Rev. 8 (2007) 507-517
    • (2007) Nat. Rev. , vol.8 , pp. 507-517
    • Akhtar, A.1    Gasser, S.M.2
  • 14
    • 33847077659 scopus 로고    scopus 로고
    • Beyond the sequence: cellular organization of genome function
    • Misteli T. Beyond the sequence: cellular organization of genome function. Cell 128 (2007) 787-800
    • (2007) Cell , vol.128 , pp. 787-800
    • Misteli, T.1
  • 15
    • 33748088991 scopus 로고    scopus 로고
    • Chromosome organization and gene control: it is difficult to see the picture when you are inside the frame
    • Verschure P.J. Chromosome organization and gene control: it is difficult to see the picture when you are inside the frame. J. Cell. Biochem. 99 (2006) 24-35
    • (2006) J. Cell. Biochem. , vol.99 , pp. 24-35
    • Verschure, P.J.1
  • 16
    • 10444232746 scopus 로고    scopus 로고
    • Chromatin organization in the mammalian nucleus
    • Gilbert N., Gilchrist S., and Bickmore W.A. Chromatin organization in the mammalian nucleus. Int. Rev. Cytol. 242 (2005) 283-336
    • (2005) Int. Rev. Cytol. , vol.242 , pp. 283-336
    • Gilbert, N.1    Gilchrist, S.2    Bickmore, W.A.3
  • 19
    • 33646729244 scopus 로고    scopus 로고
    • Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations
    • Branco M.R., and Pombo A. Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations. PLoS Biol. 4 (2006) 780-788
    • (2006) PLoS Biol. , vol.4 , pp. 780-788
    • Branco, M.R.1    Pombo, A.2
  • 20
    • 33847386173 scopus 로고    scopus 로고
    • Chromosome organization: new facts, new models
    • Branco M.R., and Pombo A. Chromosome organization: new facts, new models. Trends Cell Biol. 17 (2007) 127-134
    • (2007) Trends Cell Biol. , vol.17 , pp. 127-134
    • Branco, M.R.1    Pombo, A.2
  • 21
    • 0025649160 scopus 로고
    • A view of interphase chromosomes
    • Manuelidis L. A view of interphase chromosomes. Science 250 (1990) 1533-1540
    • (1990) Science , vol.250 , pp. 1533-1540
    • Manuelidis, L.1
  • 22
    • 0038505671 scopus 로고    scopus 로고
    • Epigenomic replication: linking epigenetics to DNA replication
    • McNairn A.J., and Gilbert D.M. Epigenomic replication: linking epigenetics to DNA replication. Bioessays 25 (2003) 647-656
    • (2003) Bioessays , vol.25 , pp. 647-656
    • McNairn, A.J.1    Gilbert, D.M.2
  • 23
    • 0033883260 scopus 로고    scopus 로고
    • MBD2-MBD3 complex binds to hemimethylated DNA and forms a complex containing DNMT1 at the replication foci in late S-phase
    • Tatematsu K.I., Yamazaki T., and Ishikawa F. MBD2-MBD3 complex binds to hemimethylated DNA and forms a complex containing DNMT1 at the replication foci in late S-phase. Genes Cells 5 (2000) 677-688
    • (2000) Genes Cells , vol.5 , pp. 677-688
    • Tatematsu, K.I.1    Yamazaki, T.2    Ishikawa, F.3
  • 24
    • 0033945861 scopus 로고    scopus 로고
    • DNMT1 binds HDAC2 and a new corepressor, DMAP1, to form a complex at replication foci
    • Rountree M.R., Bachman K.E., and Baylin S.B. DNMT1 binds HDAC2 and a new corepressor, DMAP1, to form a complex at replication foci. Nat. Genet. 25 (2000) 269-277
    • (2000) Nat. Genet. , vol.25 , pp. 269-277
    • Rountree, M.R.1    Bachman, K.E.2    Baylin, S.B.3
  • 26
    • 0034659231 scopus 로고    scopus 로고
    • De novo nucleosome assembly: new pieces in an old puzzle
    • Verreault A. De novo nucleosome assembly: new pieces in an old puzzle. Genes Dev. 14 (2000) 1430-1438
    • (2000) Genes Dev. , vol.14 , pp. 1430-1438
    • Verreault, A.1
  • 27
    • 2442660397 scopus 로고    scopus 로고
    • The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae
    • Aparicio J.G., Viggiani C.J., Gibson D.G., and Aparicio O.M. The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae. Mol. Cell. Biol. 24 (2004) 4769-4780
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4769-4780
    • Aparicio, J.G.1    Viggiani, C.J.2    Gibson, D.G.3    Aparicio, O.M.4
  • 28
    • 0036863542 scopus 로고    scopus 로고
    • Histone acetylation regulates the time of replication origin firing
    • Vogelauer M., Rubbi L., Lucas I., Brewer B.J., and Grunstein M. Histone acetylation regulates the time of replication origin firing. Mol. Cell 10 (2002) 1223-1233
    • (2002) Mol. Cell , vol.10 , pp. 1223-1233
    • Vogelauer, M.1    Rubbi, L.2    Lucas, I.3    Brewer, B.J.4    Grunstein, M.5
  • 29
    • 0037019025 scopus 로고    scopus 로고
    • Control of replication timing by a transcriptional silencer
    • Zapulla D.C., Sternglanz R., and Leatherwood J. Control of replication timing by a transcriptional silencer. Curr. Biol. 12 (2002) 869-875
    • (2002) Curr. Biol. , vol.12 , pp. 869-875
    • Zapulla, D.C.1    Sternglanz, R.2    Leatherwood, J.3
  • 30
    • 4344685735 scopus 로고    scopus 로고
    • Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly
    • Sarraf S.A., and Stancheva I. Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol. Cell 15 (2004) 595-605
    • (2004) Mol. Cell , vol.15 , pp. 595-605
    • Sarraf, S.A.1    Stancheva, I.2
  • 31
    • 13244277994 scopus 로고    scopus 로고
    • The chromatin remodeling complex NoRC controls replication timing of rRNA genes
    • Li J., Santoro R., Koberna K., and Grummt I. The chromatin remodeling complex NoRC controls replication timing of rRNA genes. EMBO J. 24 (2005) 120-127
    • (2005) EMBO J. , vol.24 , pp. 120-127
    • Li, J.1    Santoro, R.2    Koberna, K.3    Grummt, I.4
  • 32
    • 0033529791 scopus 로고    scopus 로고
    • Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication
    • Aparicio O.M., Stout A.M., and Bell S.P. Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 9130-9135
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 9130-9135
    • Aparicio, O.M.1    Stout, A.M.2    Bell, S.P.3
  • 33
    • 1642565844 scopus 로고    scopus 로고
    • Mechanisms involved in regulating DNA replication origins during the cell cycle and in response to DNA damage
    • Early A., Drury L.S., and Diffley J.F.X. Mechanisms involved in regulating DNA replication origins during the cell cycle and in response to DNA damage. Philos. Trans. R. Soc. Lond. 359 (2003) 31-38
    • (2003) Philos. Trans. R. Soc. Lond. , vol.359 , pp. 31-38
    • Early, A.1    Drury, L.S.2    Diffley, J.F.X.3
  • 34
    • 0035797444 scopus 로고    scopus 로고
    • Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint
    • Tercero J.A., and Diffley J.F.X. Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. Nature 412 (2001) 553-557
    • (2001) Nature , vol.412 , pp. 553-557
    • Tercero, J.A.1    Diffley, J.F.X.2
  • 35
    • 0038730929 scopus 로고    scopus 로고
    • A central role for DNA replication forks in checkpoint activation and response
    • Tercero J.A., Longhese M.P., and Diffley J.F.X. A central role for DNA replication forks in checkpoint activation and response. Mol. Cell 11 (2003) 1323-1336
    • (2003) Mol. Cell , vol.11 , pp. 1323-1336
    • Tercero, J.A.1    Longhese, M.P.2    Diffley, J.F.X.3
  • 37
    • 0027183088 scopus 로고
    • The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression
    • Jeppesen P., and Turner B.M. The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression. Cell 74 (1993) 281-289
    • (1993) Cell , vol.74 , pp. 281-289
    • Jeppesen, P.1    Turner, B.M.2
  • 38
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • Martin C., and Zhang Y. The diverse functions of histone lysine methylation. Mol. Cell. Biol. (2005) 838-849
    • (2005) Mol. Cell. Biol. , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 39
    • 0037078986 scopus 로고    scopus 로고
    • Establishment of transcriptional competence in early and late S-phase
    • Zhang J., Xu F., Hashimshony T., Keshet I., and Cedar H. Establishment of transcriptional competence in early and late S-phase. Nature 420 (2002) 198-202
    • (2002) Nature , vol.420 , pp. 198-202
    • Zhang, J.1    Xu, F.2    Hashimshony, T.3    Keshet, I.4    Cedar, H.5
  • 40
    • 0020041622 scopus 로고
    • Rabl's model of the interphase chromosome arrangement tested in Chinese hamster cells by premature chromosome condensation and laser-UV-microbeam experiments
    • Cremer T., Cremer C., Baumann H., Luedtke E.K., Sperling K., Teuber V., and Zorn C. Rabl's model of the interphase chromosome arrangement tested in Chinese hamster cells by premature chromosome condensation and laser-UV-microbeam experiments. Hum. Genet. 60 (1982) 46-56
    • (1982) Hum. Genet. , vol.60 , pp. 46-56
    • Cremer, T.1    Cremer, C.2    Baumann, H.3    Luedtke, E.K.4    Sperling, K.5    Teuber, V.6    Zorn, C.7
  • 41
    • 0032480023 scopus 로고    scopus 로고
    • Localization of chromosome breakpoints: implications of the chromatin structure and nuclear architecture
    • Folle G.A., Martínez-López W., Boccardo E., and Obe G. Localization of chromosome breakpoints: implications of the chromatin structure and nuclear architecture. Mutat. Res. 404 (1998) 17-26
    • (1998) Mutat. Res. , vol.404 , pp. 17-26
    • Folle, G.A.1    Martínez-López, W.2    Boccardo, E.3    Obe, G.4
  • 42
    • 0022395294 scopus 로고
    • Localization of DNAase I-sensitive sequences to specific regions in interphase nuclei
    • Hutchison N., and Weintraub H. Localization of DNAase I-sensitive sequences to specific regions in interphase nuclei. Cell 43 (1985) 471-482
    • (1985) Cell , vol.43 , pp. 471-482
    • Hutchison, N.1    Weintraub, H.2
  • 43
    • 0030806585 scopus 로고    scopus 로고
    • Localization of chromosome breakpoints induced by DNase I in Chinese hamster ovary (CHO) cells
    • Folle G.A., Boccardo E., and Obe G. Localization of chromosome breakpoints induced by DNase I in Chinese hamster ovary (CHO) cells. Chromosoma 106 (1997) 391-399
    • (1997) Chromosoma , vol.106 , pp. 391-399
    • Folle, G.A.1    Boccardo, E.2    Obe, G.3
  • 44
    • 0035142893 scopus 로고    scopus 로고
    • Chromosome regions enriched in hyperacetylated histone H4 are preferred sites for endonuclease- and radiation-induced breakpoints
    • Martínez-López W., Folle G.A., Obe G., and Jeppesen P. Chromosome regions enriched in hyperacetylated histone H4 are preferred sites for endonuclease- and radiation-induced breakpoints. Chromosome Res. 9 (2001) 69-75
    • (2001) Chromosome Res. , vol.9 , pp. 69-75
    • Martínez-López, W.1    Folle, G.A.2    Obe, G.3    Jeppesen, P.4
  • 46
    • 0026602333 scopus 로고
    • DNA double-strand breaks induced by sparsely ionizing radiation and endonucleases as critical lesions for cell death, chromosomal aberrations, mutations and oncogenic transformation
    • Obe G., Johannes C., and Schulte-Frohlinde D. DNA double-strand breaks induced by sparsely ionizing radiation and endonucleases as critical lesions for cell death, chromosomal aberrations, mutations and oncogenic transformation. Mutagenesis 7 (1992) 3-12
    • (1992) Mutagenesis , vol.7 , pp. 3-12
    • Obe, G.1    Johannes, C.2    Schulte-Frohlinde, D.3
  • 47
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou E.P., Boon C., Redon C., and Bonner W.M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146 (1999) 905-915
    • (1999) J. Cell Biol. , vol.146 , pp. 905-915
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 49
    • 84891834321 scopus 로고    scopus 로고
    • Analysis of DNA double-strand breaks by means of γ-H2AX foci
    • Obe G., and Vijayalaxmi (Eds), Springer-Verlag, Berlin, Heidelberg
    • Szumiel I. Analysis of DNA double-strand breaks by means of γ-H2AX foci. In: Obe G., and Vijayalaxmi (Eds). Chromosomal Alterations: Methods, Results and Importance in Human Health (2007), Springer-Verlag, Berlin, Heidelberg 143-158
    • (2007) Chromosomal Alterations: Methods, Results and Importance in Human Health , pp. 143-158
    • Szumiel, I.1
  • 51
    • 0016704081 scopus 로고
    • A possible function of constitutive hetrochromatin: the bodyguard hypothesis
    • Hsu T.C. A possible function of constitutive hetrochromatin: the bodyguard hypothesis. Genetics 79 (1975) 137-150
    • (1975) Genetics , vol.79 , pp. 137-150
    • Hsu, T.C.1
  • 52
    • 0347988236 scopus 로고    scopus 로고
    • Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains
    • Aten J.A., Stap J., Krawczyk P.M., van Oven C.H., Hoebe R.A., Essers J., and Kanaar K. Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. Science 303 (2004) 92-95
    • (2004) Science , vol.303 , pp. 92-95
    • Aten, J.A.1    Stap, J.2    Krawczyk, P.M.3    van Oven, C.H.4    Hoebe, R.A.5    Essers, J.6    Kanaar, K.7
  • 53
    • 0032562595 scopus 로고    scopus 로고
    • In situ visualization of DNA double-strand break repair in human fibroblasts
    • Nelms B.E., Maser R.S., Mackay J.F., Lagally M.G., and Petrini J.H. In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280 (1998) 590-592
    • (1998) Science , vol.280 , pp. 590-592
    • Nelms, B.E.1    Maser, R.S.2    Mackay, J.F.3    Lagally, M.G.4    Petrini, J.H.5
  • 55
    • 0035930537 scopus 로고    scopus 로고
    • Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
    • Ward I.M., and Chen J. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J. Biol. Chem. 276 (2001) 47759-47762
    • (2001) J. Biol. Chem. , vol.276 , pp. 47759-47762
    • Ward, I.M.1    Chen, J.2
  • 56
    • 34249937178 scopus 로고    scopus 로고
    • The ATR pathway: fine tuning the fork
    • Paulsen D.R., and Cimprich K.A. The ATR pathway: fine tuning the fork. DNA Repair 6 (2007) 953-966
    • (2007) DNA Repair , vol.6 , pp. 953-966
    • Paulsen, D.R.1    Cimprich, K.A.2
  • 57
    • 34249946978 scopus 로고    scopus 로고
    • Interplay of replication checkpoints and repair proteins at stalled replication forks
    • Branzei D., and Foiani M. Interplay of replication checkpoints and repair proteins at stalled replication forks. DNA Repair 6 (2007) 994-1003
    • (2007) DNA Repair , vol.6 , pp. 994-1003
    • Branzei, D.1    Foiani, M.2
  • 58
    • 0037810297 scopus 로고    scopus 로고
    • Effects of higher order nuclear structure and Rad 51 over expression on radiation-induced chromosome rearrangements
    • Grandy I., Hardt T., Schmid M., and Haaf T. Effects of higher order nuclear structure and Rad 51 over expression on radiation-induced chromosome rearrangements. Cytogenet. Genome Res. 98 (2002) 265-269
    • (2002) Cytogenet. Genome Res. , vol.98 , pp. 265-269
    • Grandy, I.1    Hardt, T.2    Schmid, M.3    Haaf, T.4
  • 59
  • 61
    • 2642513911 scopus 로고    scopus 로고
    • Repair rates of R-band, G-band and C-band DNA in murine and human cultured cells
    • Sanders M.H., Bates S.E., Wilbur B.S., and Holmquist G.P. Repair rates of R-band, G-band and C-band DNA in murine and human cultured cells. Cytogenet. Genome Res. 104 (2004) 35-45
    • (2004) Cytogenet. Genome Res. , vol.104 , pp. 35-45
    • Sanders, M.H.1    Bates, S.E.2    Wilbur, B.S.3    Holmquist, G.P.4
  • 62
    • 33947432388 scopus 로고    scopus 로고
    • Replication fork stalling at natural impediments
    • Mirkin E.V., and Mirkin S.M. Replication fork stalling at natural impediments. Microbiol. Mol. Biol. Rev. 71 (2007) 13-35
    • (2007) Microbiol. Mol. Biol. Rev. , vol.71 , pp. 13-35
    • Mirkin, E.V.1    Mirkin, S.M.2
  • 63
    • 10944262340 scopus 로고    scopus 로고
    • Mechanisms leading to chromosomal instability
    • Gollin S.M. Mechanisms leading to chromosomal instability. Semin. Cancer Biol. 15 (2005) 33-42
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 33-42
    • Gollin, S.M.1
  • 64
    • 0036469913 scopus 로고    scopus 로고
    • The connection between transcription and genomic instability
    • Aguilera A. The connection between transcription and genomic instability. EMBO J. 21 (2002) 195-201
    • (2002) EMBO J. , vol.21 , pp. 195-201
    • Aguilera, A.1
  • 65
    • 0024591981 scopus 로고
    • The non-random participation of human acrocentric chromosomes in Robertsonian translocations
    • Therman E., Susman B., and Denniston C. The non-random participation of human acrocentric chromosomes in Robertsonian translocations. Annu. Hum. Genet. 53 (1989) 49-65
    • (1989) Annu. Hum. Genet. , vol.53 , pp. 49-65
    • Therman, E.1    Susman, B.2    Denniston, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.