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Volumn 31, Issue 2, 2008, Pages 111-121

Beneficial effects of the rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis

Author keywords

Blood pressure; Glomerulonephritis; Rho GTPases; Rho kinase

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; HYDRALAZINE; MEMBRANE PROTEIN; NEPHRIN; PROTEIN NEPH1; PUROMYCIN AMINONUCLEOSIDE; RHO KINASE;

EID: 43049142649     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000121531     Document Type: Article
Times cited : (25)

References (66)
  • 1
    • 0037223146 scopus 로고    scopus 로고
    • Signaling: Focus on Rho in renal disease
    • Sharpe CC, Hendry BM: Signaling: focus on Rho in renal disease. J Am Soc Nephrol 2003;14:261-264.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 261-264
    • Sharpe, C.C.1    Hendry, B.M.2
  • 2
    • 0344514708 scopus 로고    scopus 로고
    • Effect of fasudil on Rhokinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats
    • Kanda T, Wakino S, Hayashi K, Homma K, Ozawa Y, Saruta T: Effect of fasudil on Rhokinase and nephropathy in subtotally nephrectomized spontaneously hypertensive rats. Kidney Int 2003;64:2009-2019.
    • (2003) Kidney Int , vol.64 , pp. 2009-2019
    • Kanda, T.1    Wakino, S.2    Hayashi, K.3    Homma, K.4    Ozawa, Y.5    Saruta, T.6
  • 6
    • 31544433970 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutic strategies of chronic renal injury: Renoprotective effect of Rho-kinase inhibitor in hypertensive glomerulosclerosis
    • Nishikimi T, Matsuoka H: Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effect of Rho-kinase inhibitor in hypertensive glomerulosclerosis. J Pharmacol Sci 2006;100:22-28.
    • (2006) J Pharmacol Sci , vol.100 , pp. 22-28
    • Nishikimi, T.1    Matsuoka, H.2
  • 7
    • 8844249337 scopus 로고    scopus 로고
    • Preventive effect of Y-27632, a selective Rho-kinase inhibitor, on ischemia/reperfusion- induced acute renal failure in rats
    • Teraishi K, Kurata H, Nakajima A, Takaoka M, Matsumura Y: Preventive effect of Y-27632, a selective Rho-kinase inhibitor, on ischemia/reperfusion- induced acute renal failure in rats. Eur J Pharmacol 2004;505:205-211.
    • (2004) Eur J Pharmacol , vol.505 , pp. 205-211
    • Teraishi, K.1    Kurata, H.2    Nakajima, A.3    Takaoka, M.4    Matsumura, Y.5
  • 9
  • 11
    • 0037466840 scopus 로고    scopus 로고
    • Cardiovascular effects of Y-27632, a selective Rho-associated kinase inhibitor, assessed in the halothane-anesthetized canine model
    • Takahara A, Sugiyama A, Satoh Y, Yoneyama M, Hashimoto K: Cardiovascular effects of Y-27632, a selective Rho-associated kinase inhibitor, assessed in the halothane-anesthetized canine model. Eur J Pharmacol 2003;460:51-57.
    • (2003) Eur J Pharmacol , vol.460 , pp. 51-57
    • Takahara, A.1    Sugiyama, A.2    Satoh, Y.3    Yoneyama, M.4    Hashimoto, K.5
  • 13
    • 0033612371 scopus 로고    scopus 로고
    • Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration
    • Seasholtz TM, Majumdatr M, Kaplan DD, Brown JH: Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration. Circ Res 1999;84:1186-1193.
    • (1999) Circ Res , vol.84 , pp. 1186-1193
    • Seasholtz, T.M.1    Majumdatr, M.2    Kaplan, D.D.3    Brown, J.H.4
  • 14
    • 0034870254 scopus 로고    scopus 로고
    • Expression of connective tissue growth factor in human renal fibroblasts: Regulatory roles of RhoA and cAMP
    • Heusinger-Ribeiro J, Eberlein M, Wahab NA, Goppelt-Stuebe M: Expression of connective tissue growth factor in human renal fibroblasts: regulatory roles of RhoA and cAMP. J Am Soc Nephrol 2001;12:1853-1861.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 1853-1861
    • Heusinger-Ribeiro, J.1    Eberlein, M.2    Wahab, N.A.3    Goppelt-Stuebe, M.4
  • 16
    • 0037062481 scopus 로고    scopus 로고
    • 3-hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathways: Implications for diabetic nephropathy
    • Danesh FR, Sadeghi MM, Amro N, Philips C, Zeng L, Lin S, Sahai A, Kanwar YS: 3-hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/p21 signaling pathways: implications for diabetic nephropathy. Proc Natl Acad Sci USA 2002;99:8301-8305.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8301-8305
    • Danesh, F.R.1    Sadeghi, M.M.2    Amro, N.3    Philips, C.4    Zeng, L.5    Lin, S.6    Sahai, A.7    Kanwar, Y.S.8
  • 17
    • 33947393625 scopus 로고    scopus 로고
    • Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro
    • Gao S, Li C, Shimokawa T, Terashita T, Matsuda S, Yaoita E, Kobayashi N: Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro. Cell Tissue Res 2007;328:391-400.
    • (2007) Cell Tissue Res , vol.328 , pp. 391-400
    • Gao, S.1    Li, C.2    Shimokawa, T.3    Terashita, T.4    Matsuda, S.5    Yaoita, E.6    Kobayashi, N.7
  • 19
    • 33645455275 scopus 로고    scopus 로고
    • Fluvastatin ameliorate podocyte injury in proteinuric rats via modulation of excessive Rho signaling
    • Shibata S, Nagase M, Fujita T: Fluvastatin ameliorate podocyte injury in proteinuric rats via modulation of excessive Rho signaling. J Am Soc Nephrol 2006;17:754-764.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 754-764
    • Shibata, S.1    Nagase, M.2    Fujita, T.3
  • 24
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 26
    • 33745444308 scopus 로고    scopus 로고
    • Angiotensin II (ANG2)-dependent activation of extracellular signal-regulated kinase (ERK) is mediated by epidermal growth factor receptor (EGFR) transactivation in glomerular podocytes
    • Flannery PJ, Spurney RF: Angiotensin II (ANG2)-dependent activation of extracellular signal-regulated kinase (ERK) is mediated by epidermal growth factor receptor (EGFR) transactivation in glomerular podocytes. Nephron 2006;103:109-118.
    • (2006) Nephron , vol.103 , pp. 109-118
    • Flannery, P.J.1    Spurney, R.F.2
  • 27
    • 0029889591 scopus 로고    scopus 로고
    • Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the Rho-binding domain
    • Reid T, Furuyashiki T, Ishizaki T, Watanabe G, Watanabe N, Fujisawa K, Morii N, Madaule P, Narumiya S: Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the Rho-binding domain. J Biol Chem 1996;271:13556-13560.
    • (1996) J Biol Chem , vol.271 , pp. 13556-13560
    • Reid, T.1    Furuyashiki, T.2    Ishizaki, T.3    Watanabe, G.4    Watanabe, N.5    Fujisawa, K.6    Morii, N.7    Madaule, P.8    Narumiya, S.9
  • 29
  • 31
    • 0036285276 scopus 로고    scopus 로고
    • Podocyte-associated molecules in puromycin aminonucleoside nephrosis of the rat
    • Luimula P, Sandstrom N, Novikov D, Hothofer H: Podocyte-associated molecules in puromycin aminonucleoside nephrosis of the rat. Lab Invest 2002;82:713-718.
    • (2002) Lab Invest , vol.82 , pp. 713-718
    • Luimula, P.1    Sandstrom, N.2    Novikov, D.3    Hothofer, H.4
  • 34
    • 0036209849 scopus 로고    scopus 로고
    • Nephrin dissociates from actin, and its expression is reduced in early experimental membranous nephropathy
    • Yuan H, Takeuchi E, Taylor GA, McLaughlin M, Brown D, Salant DJ: Nephrin dissociates from actin, and its expression is reduced in early experimental membranous nephropathy. J Am Soc Nephrol 2002;13:946-956.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 946-956
    • Yuan, H.1    Takeuchi, E.2    Taylor, G.A.3    McLaughlin, M.4    Brown, D.5    Salant, D.J.6
  • 36
    • 33748709227 scopus 로고    scopus 로고
    • Expression profile of nephrin, podocin, and CD2AP in Chinese children with MCNS and IgA nephropathy
    • Mao J, Zhang Y, Du L, Dai Y, Yang C, Liang L: Expression profile of nephrin, podocin, and CD2AP in Chinese children with MCNS and IgA nephropathy. Pediatr Nephrol 2006;21:1666-1675.
    • (2006) Pediatr Nephrol , vol.21 , pp. 1666-1675
    • Mao, J.1    Zhang, Y.2    Du, L.3    Dai, Y.4    Yang, C.5    Liang, L.6
  • 37
    • 0142213897 scopus 로고    scopus 로고
    • Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric diseases
    • Schmid H, Henger A, Cohen CD, Frach K, Grone, H, Schlondorff D, Kretzler M: Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric diseases. J Am Soc Nephrol 2003;14:2958-2966.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2958-2966
    • Schmid, H.1    Henger, A.2    Cohen, C.D.3    Frach, K.4    Grone, H.5    Schlondorff, D.6    Kretzler, M.7
  • 38
    • 32844469380 scopus 로고    scopus 로고
    • Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization
    • Ransom RF, Lam NG, Hallett MA, Atkinson SJ, Smoyer WE: Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization. Kidney Int 2005;68:2473-2483.
    • (2005) Kidney Int , vol.68 , pp. 2473-2483
    • Ransom, R.F.1    Lam, N.G.2    Hallett, M.A.3    Atkinson, S.J.4    Smoyer, W.E.5
  • 40
    • 0035164681 scopus 로고    scopus 로고
    • The murine nephrin gene is specifically expressed in kidney, brain and pancreas: Inactivation of the gene leads to massive proteinuria and neonatal death
    • Putaala H, Soininen R, Kelpelainen P, Wartiovaara J, Tryggvason K: The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death. Hum Mol Genet 2001;10:1-8.
    • (2001) Hum Mol Genet , vol.10 , pp. 1-8
    • Putaala, H.1    Soininen, R.2    Kelpelainen, P.3    Wartiovaara, J.4    Tryggvason, K.5
  • 43
    • 0042242818 scopus 로고    scopus 로고
    • Neph 1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability
    • Liu G, Kaw B, Kurfis J, Rahmanuddin S, Kanwar YS, Chugh SS: Neph 1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability. J Clin Invest 2003;112:209-221.
    • (2003) J Clin Invest , vol.112 , pp. 209-221
    • Liu, G.1    Kaw, B.2    Kurfis, J.3    Rahmanuddin, S.4    Kanwar, Y.S.5    Chugh, S.S.6
  • 46
    • 33646401549 scopus 로고    scopus 로고
    • Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
    • Verma R, Kovari I, Soofi A, Nihalani D, Patrie K, Holzman LB: Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest 2006;116:1346-1359.
    • (2006) J Clin Invest , vol.116 , pp. 1346-1359
    • Verma, R.1    Kovari, I.2    Soofi, A.3    Nihalani, D.4    Patrie, K.5    Holzman, L.B.6
  • 51
    • 0037805606 scopus 로고    scopus 로고
    • Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis-heterooligomers
    • Barletta GM, Kovari IA, Verma RK, Kerjaschki D, Holzman LB: Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis-heterooligomers. J Biol Chem 2003;278:19266-19271.
    • (2003) J Biol Chem , vol.278 , pp. 19266-19271
    • Barletta, G.M.1    Kovari, I.A.2    Verma, R.K.3    Kerjaschki, D.4    Holzman, L.B.5
  • 52
    • 0037379340 scopus 로고    scopus 로고
    • Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and Neph1
    • Gerke P, Huber TB, Sellin L, Benzing T, Walz G: Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and Neph1. J Am Soc Nephrol 2003;14:918-926.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 918-926
    • Gerke, P.1    Huber, T.B.2    Sellin, L.3    Benzing, T.4    Walz, G.5
  • 53
    • 0036226356 scopus 로고    scopus 로고
    • Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats
    • Kobayashi N, Nakano S, Mita SI, Kobayashi T, Honda T, Tsubokou Y, Matsuoka H: Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats. J Pharmacol Exp Ther 2002;301:459-466.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 459-466
    • Kobayashi, N.1    Nakano, S.2    Mita, S.I.3    Kobayashi, T.4    Honda, T.5    Tsubokou, Y.6    Matsuoka, H.7
  • 54
    • 0027269906 scopus 로고
    • Dup753 prevents the development of puromycin aminonucleoside-induced nephrosis
    • Yayama K, Kawao M, Tujii H, Itoh N, Okamoto H: Dup753 prevents the development of puromycin aminonucleoside-induced nephrosis. Eur J Pharmacol 1993;236:337-348.
    • (1993) Eur J Pharmacol , vol.236 , pp. 337-348
    • Yayama, K.1    Kawao, M.2    Tujii, H.3    Itoh, N.4    Okamoto, H.5
  • 56
    • 2942701994 scopus 로고    scopus 로고
    • Pressor responses to platelet-activating factor and thromboxane are mediated by Rho kinase
    • Martin C, Goggel R, Ressmeyer AR, Uhlig S: Pressor responses to platelet-activating factor and thromboxane are mediated by Rho kinase. Am J Physiol 2004;287:L250-L257.
    • (2004) Am J Physiol , vol.287
    • Martin, C.1    Goggel, R.2    Ressmeyer, A.R.3    Uhlig, S.4
  • 57
    • 0035895524 scopus 로고    scopus 로고
    • Leukotriene D4-induced Rho-mediated actin reorganization in human bronchial smooth muscle cells
    • Saeguse S, Tsubone H, Kuwahara M: Leukotriene D4-induced Rho-mediated actin reorganization in human bronchial smooth muscle cells. Eur J Pharmacol 2001;413:163-171.
    • (2001) Eur J Pharmacol , vol.413 , pp. 163-171
    • Saeguse, S.1    Tsubone, H.2    Kuwahara, M.3
  • 58
    • 0022596677 scopus 로고
    • Eicosanoids in experimental human renal disease
    • Stork JE, Rahman MA, Dunn MJ: Eicosanoids in experimental human renal disease. Am J Med 1986;80:34-45.
    • (1986) Am J Med , vol.80 , pp. 34-45
    • Stork, J.E.1    Rahman, M.A.2    Dunn, M.J.3
  • 59
    • 0032893545 scopus 로고    scopus 로고
    • Potential role of platelet activating factor in acute renal failure
    • Lopez-Novoa J: Potential role of platelet activating factor in acute renal failure. Kidney Int 1999;55:1672-1682.
    • (1999) Kidney Int , vol.55 , pp. 1672-1682
    • Lopez-Novoa, J.1
  • 60
    • 0031727290 scopus 로고    scopus 로고
    • Leukotrienes and lipoxins: Lipoxygenase-derived modulators of leukocyte recruitment and vascular tone in glomerulonephritis
    • Clarkson MR, McGinty A, Godson C, Brady HR: Leukotrienes and lipoxins: lipoxygenase-derived modulators of leukocyte recruitment and vascular tone in glomerulonephritis. Nephol Dial Transplant 1998;13:3043-3051.
    • (1998) Nephol Dial Transplant , vol.13 , pp. 3043-3051
    • Clarkson, M.R.1    McGinty, A.2    Godson, C.3    Brady, H.R.4
  • 61
    • 0033812037 scopus 로고    scopus 로고
    • Kidney angiotensin receptors and their role in renal pathophysiology
    • Sanderberg KJH: Kidney angiotensin receptors and their role in renal pathophysiology. Semin Nephrol 2000;20:402-416.
    • (2000) Semin Nephrol , vol.20 , pp. 402-416
    • Sanderberg, K.J.H.1
  • 62
    • 0027526959 scopus 로고
    • Endothelins in the kidney: Physiology and pathophysiology
    • Kohan DE: Endothelins in the kidney: physiology and pathophysiology. Am J Kidney Dis 1993;22:493-510.
    • (1993) Am J Kidney Dis , vol.22 , pp. 493-510
    • Kohan, D.E.1
  • 64
    • 33750693942 scopus 로고    scopus 로고
    • Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice
    • Fu P, Liu F, Su S, Wang W, Huang XR, Entman ML, Schwartz RJ, Wei L, Lan HY: Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice. J Am Soc Nephrol 2006;17:3105-3114.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3105-3114
    • Fu, P.1    Liu, F.2    Su, S.3    Wang, W.4    Huang, X.R.5    Entman, M.L.6    Schwartz, R.J.7    Wei, L.8    Lan, H.Y.9
  • 65
    • 0030733851 scopus 로고    scopus 로고
    • Induction of differentiation in cultured rat and human podocytes
    • Mundel P, Reiser J, Kriz W: Induction of differentiation in cultured rat and human podocytes. J Am Soc Nephrol 1997;8:697-705.
    • (1997) J Am Soc Nephrol , vol.8 , pp. 697-705
    • Mundel, P.1    Reiser, J.2    Kriz, W.3


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