Nephrin in experimental glomerular disease

Kidney International

Volumn 58, Issue 4, 2000, Pages 1461-1468

  Luimula, Pauliina ^a,b   Ahola, Heikki ^a,b   Wang, Shi Xuan ^a,b   Solin, Marja Liisa ^a,b   Aaltonen, Petri ^a,b   Tikkanen, Ilkka ^a,b   Kerjaschki, Dontscho ^a,b   Holthöfer, Harry ^a,b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Experimental models; Glomerulonephritis; Lipid peroxidation; Proteinuria; Slit diaphragm

Indexed keywords

GENE PRODUCT; MERCURIC CHLORIDE; MESSENGER RNA; NEPHRIN; PUROMYCIN AMINONUCLEOSIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONGENITAL NEPHROTIC SYNDROME; CONTROLLED STUDY; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; KIDNEY CORTEX; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; PROTEINURIA; RAT;

EID: 0033807362     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00308.x     Document Type: Article

References (31)

1. Positionally cloned gene for a novel glomerular protein-nephrin is mutated in congenital nephrotic syndrome
2. Structure of the gene for congenital nephrotic syndrome of the Finnish type (NPHS1) and characterization of mutations
3. Nephrin localizes at the podocyte filtration area and is characteristically spliced in the human kidney
4. Nephrin is specifically located at the slit diaphragm of glomerular podocytes
5. Alterations of the glomerular epithelium in acute aminonucleoside nephrosis: Evidence for formation of occluding junctions and epithelial cell detachment
6. Aminonucleoside nephrosis. I. Electronmicroscopic study of renal lesions in rats
7. Current status of the structural and functional basis of glomerular filtration and proteinuria
8. Dysfunctions of cell biological mechanisms of visceral epithelial cell (podocytes) in glomerular diseases
9. Production of nephrotic syndrome in rats by Freund's adjuvant and rat kidney suspension
10. Cloning and expression of the rat nephrin homolog
11. Chronic inhibition of nitric oxide synthase in Heymann nephritis
12. Altered gene expression and functions of mitochondria in human nephrotic syndrome
13. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
14. Rapid isolation of both double-stranded RNA and PCR-suitable DNA from the obligate biotrophic phytopathogenic fungus Uncinula necator using a commercially available reagent
15. Novel mouse embryonic renal marker gene products differentially expressed during kidney development
16. Nephron segment and cell-type specific expression of gangliosides in the developing and adult kidney
17. Pathogenic antibodies inhibit the binding of apolipoproteins to megalin/gp 330 in passive Heymann nephritis
18. Massive proteinuria induced in rats by a single intravenous injection of a monoclonal antibody
19. Nephritogenic mAb 5-1- 6 is directed at the extracellular domain of nephrin
20. Alternative splicing of the mRNA coding for the human endothelial angiotensin converting enzyme: A new mechanism for solubilization
21. Development of the metanephric kidney
22. Genetic susceptibility to systemic lupus erythematosus
23. Glomerular expression of nephrin is decreased in acquired human nephrotic syndrome
24. A role for oxygen free radicals in aminonucleoside nephrosis
25. Roles of active oxygen species in glomerular epithelial cell injury in vitro caused by puromycin aminonucleoside
26. Reactive oxygen species in puromycin aminonucleoside nephrosis: In vitro studies
27. Molecular mechanisms of glomerular injury in rat experimental membranous nephropathy (Heymann nephritis)
28. Mercury accumulation in kidney lysosomes or proteinuric rats
29. Mitochondrial bioenergetics during the initiation of mercuric chloride-induced renal injury. II. Functional alterations of renal cortical mitochondria isolated after mercuric chloride treatment
30. The tight junction protein ZO- 1 is concentrated along slit diaphragms of the glomerular epithelium
31. Protein interactions at the tight junction. Actin has a multiple binding partners, and zo-1 forms independent complexes with zo-2 and zo- 3