-
1
-
-
0034056019
-
Nutrition and dietary carcinogens
-
Sugimura T: Nutrition and dietary carcinogens. Carcinogenesis 2000;21:387-395.
-
(2000)
Carcinogenesis
, vol.21
, pp. 387-395
-
-
Sugimura, T.1
-
3
-
-
0027193044
-
Exposure to heterocyclic amines
-
Wakabayashi K, Ushijima H, Takahashi M, Nukaya H, Kim SB, Hirose M, Ochiai M, Sugimura T, Nagao M: Exposure to heterocyclic amines. Environ Health Perspect 1993;99:129-133.
-
(1993)
Environ Health Perspect
, vol.99
, pp. 129-133
-
-
Wakabayashi, K.1
Ushijima, H.2
Takahashi, M.3
Nukaya, H.4
Kim, S.B.5
Hirose, M.6
Ochiai, M.7
Sugimura, T.8
Nagao, M.9
-
4
-
-
0027215566
-
Detection of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in beer and wine
-
Manabe S, Suzuki H, Wada O, Ueki A: Detection of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in beer and wine. Carcinogenesis 1993;14:899-901.
-
(1993)
Carcinogenesis
, vol.14
, pp. 899-901
-
-
Manabe, S.1
Suzuki, H.2
Wada, O.3
Ueki, A.4
-
5
-
-
0025986958
-
Detection of a carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in cigarette smoke condensate
-
Manabe S, Tohyama K, Wada O, Aramaki T: Detection of a carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in cigarette smoke condensate. Carcinogenesis 1991;12:1945-1947.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1945-1947
-
-
Manabe, S.1
Tohyama, K.2
Wada, O.3
Aramaki, T.4
-
7
-
-
1942504286
-
Heterocyclic amines: Mutagens/ carcinogens produced during cooking of meat and fish
-
Sugimura T, Wakabayashi K, Nakagama H, Nagao M: Heterocyclic amines: mutagens/ carcinogens produced during cooking of meat and fish. Cancer Sci 2004;95:290-299.
-
(2004)
Cancer Sci
, vol.95
, pp. 290-299
-
-
Sugimura, T.1
Wakabayashi, K.2
Nakagama, H.3
Nagao, M.4
-
8
-
-
0025768966
-
A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP)
-
Ito N, Hasegawa R, Sano M, Tamano S, Esumi H, Takayama S, Sugimura T: A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis 1991;12:1503-1506.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1503-1506
-
-
Ito, N.1
Hasegawa, R.2
Sano, M.3
Tamano, S.4
Esumi, H.5
Takayama, S.6
Sugimura, T.7
-
9
-
-
0027787536
-
Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]- pyridine (PhIP) carcinogenicity in rats
-
Hasegawa R, Sano M, Tamano S, Imaida K, Shirai T, Nagao M, Sugimura T, Ito N: Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]- pyridine (PhIP) carcinogenicity in rats. Carcinogenesis 1993;14:2553-2557.
-
(1993)
Carcinogenesis
, vol.14
, pp. 2553-2557
-
-
Hasegawa, R.1
Sano, M.2
Tamano, S.3
Imaida, K.4
Shirai, T.5
Nagao, M.6
Sugimura, T.7
Ito, N.8
-
10
-
-
14444288520
-
The prostate: A target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine (PhIP) derived from cooked foods
-
Shirai T, Sano M, Tamano S, Takahashi S, Hirose M, Futakuchi M, Hasegawa R, Imaida K, Matsumoto K, Wakabayashi K, Sugimura T, Ito N: The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine (PhIP) derived from cooked foods. Cancer Res 1997;57:195-198.
-
(1997)
Cancer Res
, vol.57
, pp. 195-198
-
-
Shirai, T.1
Sano, M.2
Tamano, S.3
Takahashi, S.4
Hirose, M.5
Futakuchi, M.6
Hasegawa, R.7
Imaida, K.8
Matsumoto, K.9
Wakabayashi, K.10
Sugimura, T.11
Ito, N.12
-
11
-
-
33847065970
-
The dietary charred meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine acts as both a tumor initiator and promoter in the rat ventral prostate
-
Nakai Y, Nelson WG, DeMarzo AM: The dietary charred meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine acts as both a tumor initiator and promoter in the rat ventral prostate. Cancer Res 2007;67:1378-1384.
-
(2007)
Cancer Res
, vol.67
, pp. 1378-1384
-
-
Nakai, Y.1
Nelson, W.G.2
DeMarzo, A.M.3
-
12
-
-
0036200869
-
Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine in combination with a high fat diet
-
Ubagai T, Ochiai M, Kawamori T, Imai H, Sugimura T, Nagao M, Nakagama H: Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine in combination with a high fat diet. Carcinogenesis 2002;23:197-200.
-
(2002)
Carcinogenesis
, vol.23
, pp. 197-200
-
-
Ubagai, T.1
Ochiai, M.2
Kawamori, T.3
Imai, H.4
Sugimura, T.5
Nagao, M.6
Nakagama, H.7
-
13
-
-
0036265736
-
Mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the mammary gland of Big Blue rats on high-and low-fat diets
-
Yu M, Jones ML, Gong M, Sinha R, Schut HA, Snyderwine EG: Mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the mammary gland of Big Blue rats on high-and low-fat diets. Carcinogenesis 2002;23:877-884.
-
(2002)
Carcinogenesis
, vol.23
, pp. 877-884
-
-
Yu, M.1
Jones, M.L.2
Gong, M.3
Sinha, R.4
Schut, H.A.5
Snyderwine, E.G.6
-
14
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 1990;61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
15
-
-
0036119631
-
-
Futakuchi M, Hirose M, Imaida K, Takahashi S, Ogawa K, Asamoto M, Miki T, Shirai T: Chemoprevention of 2-amino-1-methyl-6-phenylimidazo-[4,5-b] pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5- trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats. Carcinogenesis 2002;23:283-287.
-
Futakuchi M, Hirose M, Imaida K, Takahashi S, Ogawa K, Asamoto M, Miki T, Shirai T: Chemoprevention of 2-amino-1-methyl-6-phenylimidazo-[4,5-b] pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5- trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats. Carcinogenesis 2002;23:283-287.
-
-
-
-
16
-
-
0027993261
-
Synergistic enhancement of small and large intestinal carcinogenesis by combined treatment of rats with five heterocyclic amines in a medium-term multi-organ bioassay
-
Hasegawa R, Tanaka H, Tamano S, Shirai T, Nagao M, Sugimura T, Ito N: Synergistic enhancement of small and large intestinal carcinogenesis by combined treatment of rats with five heterocyclic amines in a medium-term multi-organ bioassay. Carcinogenesis 1994;15:2567-2573.
-
(1994)
Carcinogenesis
, vol.15
, pp. 2567-2573
-
-
Hasegawa, R.1
Tanaka, H.2
Tamano, S.3
Shirai, T.4
Nagao, M.5
Sugimura, T.6
Ito, N.7
-
17
-
-
3242812054
-
Existence of a threshold for induction of aberrant crypt foci in the rat colon with low doses of 2-amino-1-methyl-6-phenolimidazo[4,5-b] pyridine
-
Fukushima S, Wanibuchi H, Morimura K, Iwai S, Nakae D, Kishida H, Tsuda H, Uehara N, Imaida K, Shirai T, Tatematsu M, Tsukamoto T, Hirose M, Furukawa F: Existence of a threshold for induction of aberrant crypt foci in the rat colon with low doses of 2-amino-1-methyl-6-phenolimidazo[4,5-b] pyridine. Toxicol Sci 2004;80:109-114.
-
(2004)
Toxicol Sci
, vol.80
, pp. 109-114
-
-
Fukushima, S.1
Wanibuchi, H.2
Morimura, K.3
Iwai, S.4
Nakae, D.5
Kishida, H.6
Tsuda, H.7
Uehara, N.8
Imaida, K.9
Shirai, T.10
Tatematsu, M.11
Tsukamoto, T.12
Hirose, M.13
Furukawa, F.14
-
18
-
-
20344388286
-
Lack of large intestinal carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine at low doses in rats initiated with azoxymethane
-
Doi K, Wanibuchi H, Salim EI, Morimura K, Kinoshita A, Kudoh S, Hirata K, Yoshikawa J, Fukushima S: Lack of large intestinal carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine at low doses in rats initiated with azoxymethane. Int J Cancer 2005;115:870-878.
-
(2005)
Int J Cancer
, vol.115
, pp. 870-878
-
-
Doi, K.1
Wanibuchi, H.2
Salim, E.I.3
Morimura, K.4
Kinoshita, A.5
Kudoh, S.6
Hirata, K.7
Yoshikawa, J.8
Fukushima, S.9
-
19
-
-
0034830884
-
Analysis of K-ras, APC, and β-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis
-
Takayama T, Ohi M, Hayashi T, Miyanishi K, Nobuoka A, Nakajima T, Satoh T, Takimoto R, Kato J, Sakamaki S, Niitsu Y: Analysis of K-ras, APC, and β-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis. Gastroenterology 2001;121:599-611.
-
(2001)
Gastroenterology
, vol.121
, pp. 599-611
-
-
Takayama, T.1
Ohi, M.2
Hayashi, T.3
Miyanishi, K.4
Nobuoka, A.5
Nakajima, T.6
Satoh, T.7
Takimoto, R.8
Kato, J.9
Sakamaki, S.10
Niitsu, Y.11
-
20
-
-
1642527133
-
Rapid analysis of gene expression changes caused by liver carcinogens and chemopreventive agents using a newly developed three-dimensional microarray system
-
Hokaiwado N, Asamoto M, Tsujimura K, Hirota T, Ichihara T, Satoh T, Shirai T: Rapid analysis of gene expression changes caused by liver carcinogens and chemopreventive agents using a newly developed three-dimensional microarray system. Cancer Sci 2004;95:123-130.
-
(2004)
Cancer Sci
, vol.95
, pp. 123-130
-
-
Hokaiwado, N.1
Asamoto, M.2
Tsujimura, K.3
Hirota, T.4
Ichihara, T.5
Satoh, T.6
Shirai, T.7
-
21
-
-
31644436475
-
Lack of modification of 2-amino-3,8-dimethylimidazo[ 4,5-f]quinoxaline (MeIQx) rat hepatocarcinogenesis by caffeine, a CYP1A2 inducer, points to complex counteracting influences
-
Kuribayashi M, Asamoto M, Suzuki S, Hokaiwado N, Ogawa K, Shirai T: Lack of modification of 2-amino-3,8-dimethylimidazo[ 4,5-f]quinoxaline (MeIQx) rat hepatocarcinogenesis by caffeine, a CYP1A2 inducer, points to complex counteracting influences. Cancer Lett 2006;232:289-299.
-
(2006)
Cancer Lett
, vol.232
, pp. 289-299
-
-
Kuribayashi, M.1
Asamoto, M.2
Suzuki, S.3
Hokaiwado, N.4
Ogawa, K.5
Shirai, T.6
-
22
-
-
0034469444
-
Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development
-
Bromberg J: Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development. Breast Cancer Res 2000;2:86-90.
-
(2000)
Breast Cancer Res
, vol.2
, pp. 86-90
-
-
Bromberg, J.1
-
23
-
-
0032125574
-
IFN-γ induces cell growth inhibition by Fas-mediated apoptosis: Requirement of STAT1 protein for up-regulation of Fas and FasL expression
-
Xu X, Fu X-Y, Plate J, Chong A: IFN-γ induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression. Cancer Res 1998;58:2832-2837.
-
(1998)
Cancer Res
, vol.58
, pp. 2832-2837
-
-
Xu, X.1
Fu, X.-Y.2
Plate, J.3
Chong, A.4
-
24
-
-
25444481030
-
Effect of p53 status and STAT1 on chemotherapy-induced, Fas-mediated apoptosis in colorectal cancer
-
McDermott U, Longley DB, Galligan L, Allen W, Wilson T, Johnston PG: Effect of p53 status and STAT1 on chemotherapy-induced, Fas-mediated apoptosis in colorectal cancer. Cancer Res 2005;65:8951-8960.
-
(2005)
Cancer Res
, vol.65
, pp. 8951-8960
-
-
McDermott, U.1
Longley, D.B.2
Galligan, L.3
Allen, W.4
Wilson, T.5
Johnston, P.G.6
-
25
-
-
32144445912
-
Decreased STAT1 expression by promoter methylation in squamous cell carcinogenesis
-
Xi S, Dyer KF, Kimak M, Zhang Q, Gooding WE, Chaillet JR, Chai RL, Ferrell RE, Zamboni B, Hunt J, Grandis JR: Decreased STAT1 expression by promoter methylation in squamous cell carcinogenesis. J Natl Cancer Inst 2006;98:181-189.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 181-189
-
-
Xi, S.1
Dyer, K.F.2
Kimak, M.3
Zhang, Q.4
Gooding, W.E.5
Chaillet, J.R.6
Chai, R.L.7
Ferrell, R.E.8
Zamboni, B.9
Hunt, J.10
Grandis, J.R.11
-
26
-
-
33745025705
-
IFNγ-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice
-
Hanada T, Kobayashi T, Chinen T, Saeki K, Takaki H, Koga K, Minoda Y, Sanada T, Yoshioka T, Mimata H, Kato S, Yoshimura A: IFNγ-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice. J Exp Med 2006;203:1391-1397.
-
(2006)
J Exp Med
, vol.203
, pp. 1391-1397
-
-
Hanada, T.1
Kobayashi, T.2
Chinen, T.3
Saeki, K.4
Takaki, H.5
Koga, K.6
Minoda, Y.7
Sanada, T.8
Yoshioka, T.9
Mimata, H.10
Kato, S.11
Yoshimura, A.12
-
27
-
-
84970070220
-
Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer
-
Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM: Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 1995;55:3964-3968.
-
(1995)
Cancer Res
, vol.55
, pp. 3964-3968
-
-
Takahashi, Y.1
Kitadai, Y.2
Bucana, C.D.3
Cleary, K.R.4
Ellis, L.M.5
-
28
-
-
0030869787
-
Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element
-
Mazure NM, Chen EY, Laderoute KR, Giaccia AJ: Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 1997;90:3322-3331.
-
(1997)
Blood
, vol.90
, pp. 3322-3331
-
-
Mazure, N.M.1
Chen, E.Y.2
Laderoute, K.R.3
Giaccia, A.J.4
-
29
-
-
0033215389
-
Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cells
-
Jung YD, Nakano K, Liu W, Gallick GE, Ellis LM: Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cells. Cancer Res 1999;59:4804-4807.
-
(1999)
Cancer Res
, vol.59
, pp. 4804-4807
-
-
Jung, Y.D.1
Nakano, K.2
Liu, W.3
Gallick, G.E.4
Ellis, L.M.5
-
30
-
-
0035882030
-
Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia
-
Zhang X, Gaspard JP, Chung DC: Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia. Cancer Res 2001;61:6050-6054.
-
(2001)
Cancer Res
, vol.61
, pp. 6050-6054
-
-
Zhang, X.1
Gaspard, J.P.2
Chung, D.C.3
-
31
-
-
0036793827
-
Blockade of insulin-like growth factor I receptor function inhibits growth and angiogenesis of colon cancer
-
Reinmuth N, Liu W, Fan F, Jung YD, Ahmad SA, Stoeltzing O, Bucana CD, Radinsky R, Ellis LM: Blockade of insulin-like growth factor I receptor function inhibits growth and angiogenesis of colon cancer. Clin Cancer Res 2002;8:3259-3269.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3259-3269
-
-
Reinmuth, N.1
Liu, W.2
Fan, F.3
Jung, Y.D.4
Ahmad, S.A.5
Stoeltzing, O.6
Bucana, C.D.7
Radinsky, R.8
Ellis, L.M.9
-
32
-
-
10344222094
-
The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is a potent oestrogen: A mechanistic basis for its tissue-specific carcinogenicity
-
Lauber SN, Ali S, Gooderham NJ: The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity. Carcinogenesis 2004;25:2509-2517.
-
(2004)
Carcinogenesis
, vol.25
, pp. 2509-2517
-
-
Lauber, S.N.1
Ali, S.2
Gooderham, N.J.3
-
33
-
-
0141484615
-
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
-
Kamal A, Thao L, Sensintaffar J, Zhang L, Boehm MF, Fritz LC, Burrows FJ: A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 2003;425:407-410.
-
(2003)
Nature
, vol.425
, pp. 407-410
-
-
Kamal, A.1
Thao, L.2
Sensintaffar, J.3
Zhang, L.4
Boehm, M.F.5
Fritz, L.C.6
Burrows, F.J.7
-
34
-
-
4344607005
-
Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine
-
Fujiwara K, Ochiai M, Ohta T, Ohki M, Aburatani H, Nagao M, Sugimura T, Nakagama H: Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[ 4,5-b]pyridine. Carcinogenesis 2004;25:1495-1505.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1495-1505
-
-
Fujiwara, K.1
Ochiai, M.2
Ohta, T.3
Ohki, M.4
Aburatani, H.5
Nagao, M.6
Sugimura, T.7
Nakagama, H.8
-
35
-
-
28444478039
-
Modeling human colon cancer in rodents using a food-borne carcinogen, PhIP
-
Nakagama H, Nakanishi M, Ochiai M: Modeling human colon cancer in rodents using a food-borne carcinogen, PhIP. Cancer Sci 2005;96:627-636.
-
(2005)
Cancer Sci
, vol.96
, pp. 627-636
-
-
Nakagama, H.1
Nakanishi, M.2
Ochiai, M.3
-
36
-
-
0036798690
-
cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthra cene
-
Shan L, He M, Yu M, Qiu C, Lee NH, Liu ET, Snyderwine EG: cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthra cene. Carcinogenesis 2002;23:1561-1568.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1561-1568
-
-
Shan, L.1
He, M.2
Yu, M.3
Qiu, C.4
Lee, N.H.5
Liu, E.T.6
Snyderwine, E.G.7
|