Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis

PLoS Medicine

Volumn 3, Issue 2, 2006, Pages 0230-0235

  Barreiro, Luis B ^a   Neyrolles, Olivier ^a   Babb, Chantal L ^b   Tailleux, Ludovic ^a   Quach, Hélène ^a   McElreavey, Ken ^a   Van Helden, Paul D ^b   Hoal, Eileen G ^b   Gicquel, Brigitte ^a   Quintana Murci, Lluís ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CD209 ANTIGEN; GENE PRODUCT; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; DC-SPECIFIC ICAM-3 GRABBING NONINTEGRIN; LECTIN;

ADULT; AFRICA; ALLELE; ARTICLE; ASIAN; BACTERIAL VIRULENCE; COHORT ANALYSIS; CONTROLLED STUDY; EUROPE; EVOLUTIONARY ADAPTATION; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HOST PATHOGEN INTERACTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; PATHOGENESIS; PROMOTER REGION; RACE DIFFERENCE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH AFRICA; TUBERCULOSIS; CASE CONTROL STUDY; DENDRITIC CELL; GENETIC PREDISPOSITION; GENETICS; LUNG TUBERCULOSIS; MIDDLE AGED; NEGRO; PATHOGENICITY; PATHOPHYSIOLOGY; PHYLOGENY; PHYSIOLOGY; RISK FACTOR;

ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CELL ADHESION MOLECULES; DENDRITIC CELLS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LECTINS, C-TYPE; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RECEPTORS, CELL SURFACE; RISK FACTORS; SOUTH AFRICA; TUBERCULOSIS, PULMONARY;

EID: 33644836015     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.0030020     Document Type: Article

References (47)

1. Frieden TR, Sterling TR, Munsiff SS, Watt CJ, Dye C (2003) Tuberculosis. Lancet 362: 887-899.
2. Enarson DA, Rouillon A (1994) The epidemiological basis of tuberculosis control. In: Davies PD, editor. Clinical tuberculosis. London: Chapman and Hall. pp 19-32.
3. Lienhardt C (2001) From exposure to disease: The role of environmental factors in susceptibility to and development of tuberculosis. Epidemiol Rev 23: 288-301.
4. Bellamy R (2003) Susceptibility to mycobacterial infections: The importance of host genetics. Genes Immun 4: 4-11.
5. Blackwell JM (2001) Genetics and genomics in infectious disease susceptibility. Trends Mol Med 7: 521-526.
6. Cooke GS, Hill AV (2001) Genetics of susceptibility to human infectious disease. Nat Rev Genet 2: 967-977.
7. Casanova JL, Abel L (2002) Genetic dissection of immunity to mycobacteria: The human model. Annu Rev Immunol 20: 581-620.
8. Janeway CA Jr., Medzhitov R (2002) Innate immune recognition. Annu Rev Immunol 20: 197-216.
9. Kimbrell DA, Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-267.
10. Taylor PR, Martinez-Pomares L, Stacey M, Lin HH, Brown GD, et al. (2005) Macrophage receptors and immune recognition. Annu Rev Immunol 23: 901-944.
11. Medzhitov R (2001) Toll-like receptors and innate immunity. Nat Rev Immunol 1: 135-145.
12. Fujita T (2002) Evolution of the lectin-complement pathway and its role in innate immunity. Nat Rev Immunol 2: 346-353.
13. McGreal EP, Miller JL, Gordon S (2005) Ligand recognition by antigen-presenting cell C-type lectin receptors. Curr Opin Immunol 17: 18-24.
14. Tailleux L, Schwartz O, Herrmann J, Pivert E, Jackson M, et al. (2003) DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells. J Exp Med 197: 121-127.
15. Soilleux EJ, Morris LS, Leslie G, Chehimi J, Luo Q, et al. (2002) Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro. J Leukoc Biol 71: 445-457.
16. Geijtenbeek TB, Torensma R, van Vliet SJ, van Duijnhoven GC, Adema GJ, et al. (2000) Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 100: 575-585.
17. Geijtenbeek TB, Krooshoop DJ, Bleijs DA, van Vliet SJ, van Duijnhoven GC, et al. (2000) DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking. Nat Immunol 1: 353-357.
18. Geijtenbeek TB, van Vliet SJ, Engering A, 't Hart BA, van Kooyk Y (2004) Self- and nonself-recognition by C-type lectins on dendritic cells. Annu Rev Immunol 22: 33-54.
19. Geijtenbeek TB, Kwon DS, Torensma R, van Vliet SJ, van Duijnhoven GC, et al. (2000) DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 100: 587-597.
20. Alvarez CP, Lasala F, Carrillo J, Muniz O, Corbi AL, et al. (2002) C-type lectins DC-SIGN and L-SIGN mediate cellular entry by Ebola virus in cis and in trans. J Virol 76: 6841-6844.
21. Halary F, Amara A, Lortat-Jacob H, Messerle M, Delaunay T, et al. (2002) Human cytomegalovirus binding to DC-SIGN is required for dendritic cell infection and target cell trans-infection. Immunity 17: 653-664.
22. Lozach PY, Lortat-Jacob H, de Lacroix de Lavalette A, Staropoli I, Foung S, et al. (2003) DC-SIGN and L-SIGN are high-affinity binding receptors for hepatitis C virus glycoprotein E2. J Biol Chem 278: 20358-20366.
23. Tassaneetrithep B, Burgess TH, Granelli-Piperno A, Trumpfheller C, Finke J, et al. (2003) DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J Exp Med 197: 823-829.
24. Marzi A, Gramberg T, Simmons G, Moller P, Rennekamp AJ, et al. (2004) DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus. J Virol 78: 12090-12095.
25. Bergman MP, Engering A, Smits HH, van Vliet SJ, van Bodegraven AA, et al. (2004) Helicobacter pylori modulates the T helper cell 1/T helper cell 2 balance through phase-variable interaction between lipopolysaccharide and DC-SIGN. J Exp Med 200: 979-990.
26. Appelmelk BJ, van Die I, van Vliet SJ, Vandenbroucke-Grauls CM, Geijtenbeek TB, et al. (2003) Carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific ICAM-3-grabbing nonintegrin on dendritic cells. J Immunol 170: 1635-1639.
27. Colmenares M, Puig-Kroger A, Pello OM, Corbi AL, Rivas L (2002) Dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN, CD209), a C-type surface lectin in human DCs, is a receptor for Leishmania amastigotes. J Biol Chem 277: 36766-36769.
28. Geijtenbeek T, van Vliet S, Koppel E, Sanchez-Hernandez M, Vandenbroucke-Grauls C, et al. (2003) Mycobacteria target DC-SIGN to suppress dendritic cell function. J Exp Med 197: 7-17.
29. Tailleux L, Maeda N, Nigou J, Gicquel B, Neyrolles O (2003) How is the phagocyte lectin keyboard played? Master class lesson by Mycobacterium tuberculosis. Trends Microbiol 11: 259-263.
30. Beyers N, Gie RP, Zietsman HL, Kunneke M, Hauman J, et al. (1996) The use of a geographical information system (GIS) to evaluate the distribution of tuberculosis in a high-incidence community. S Afr Med J 86: 40-41, 44.
31. van der Ross RE (1993) 100 questions about Coloured South Africans. Cape Town (South Africa): UWC Printing Department. 36 p.
32. Nurse GT, Weiner JS, Jenkins T (1985) The peoples of Southern Africa and their affinities. Oxford (United Kingdom): Clarendon Press. 410 p.
33. Munch Z, Van Lill SW, Booysen CN, Zietsman HL, Enarson DA, et al. (2003) Tuberculosis transmission patterns in a high-incidence area: A spatial analysis. Int J Tuberc Lung Dis 7: 271-277.
34. Beyers N, Michaelis I, Gie R, Schaaf HS, Richardson M, et al. (2001) Transmission of tuberculosis (TB) to children in a high incidence area. Int J Tuberc Lung Dis 5: S185.
35. Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265.
36. Stephens M, Donnelly P (2003) A comparison of Bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73: 1162-1169.
37. Sebastiani P, Lazarus R, Weiss ST, Kunkel LM, Kohane IS, et al. (2003) Minimal haplotype tagging. Proc Natl Acad Sci U S A 100: 9900-9905.
38. Pritchard JK, Rosenberg NA (1999) Use of unlinked genetic markers to detect population stratification in association studies. Am J Hum Genet 65: 220-228.
39. Reich DE, Goldstein DB (2001) Detecting association in a case-control study while correcting for population stratification. Genet Epidemiol 20: 4-16.
40. O'Brien SJ (1991) Ghetto legacy. Curr Biol 1: 209-211.
41. Stead WW, Senner JW, Reddick WT, Lofgren JP (1990) Racial differences in susceptibility to infection by Mycobacterium tuberculosis. N Engl J Med 322: 422-427.
42. Stead WW (1992) Genetics and resistance to tuberculosis. Could resistance be enhanced by genetic engineering? Ann Intern Med 116: 937-941.
43. Daniel TM, Bates JH, Downes KA (1994) History of tuberculosis. In: Bloom BR, editor. Tuberculosis: Pathogenesis, protection, control. Washington, DC: ASM Press. pp 13-24.
44. Lipsitch M, Sousa AO (2002) Historical intensity of natural selection for resistance to tuberculosis. Genetics 161: 1599-1607.
45. Martin MP, Lederman MM, Hutcheson HB, Goedert JJ, Nelson GW, et al. (2004) Association of DC-SIGN promoter polymorphism with increased risk for parenteral, but not mucosal, acquisition of human immunodeficiency virus type 1 infection. J Virol 78: 14053-14056.
46. Sakuntabhai A, Turbpaiboon C, Casademont I, Chuansumrit A, Lowhnoo T, et al. (2005) A variant in the CD209 promoter is associated with severity of dengue disease. Nat Genet 37: 507-513.
47. Tailleux L, Pham-Thi N, Bergeron-Lafaurie N, Herrmann JL, Charles P, et al. (2005) DC-SIGN induction in alveolar macrophages defines a privileged target host cell population for mycobacteria in patients with tuberculosis. PLoS Med (2)12: e381.