A polymorphism in toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis

Journal of Infectious Diseases

Volumn 194, Issue 8, 2006, Pages 1127-1134

  Hawn, Thomas R ^a,b   Dunstan, Sarah J ^f,i   Thwaites, Guy E ^f   Simmons, Cameron P ^f,i   Thuong Thuong, Nguyen ^f,g   Lan, Nguyen Thi Ngoc ^e   Quy, Hoang Thi ^e   Chau, Tran Thi Hong ^g   Hieu, Nguyen T ^h   Rodrigues, Stephanie ^b   Janer, Marta ^b   Zhao, Lue Ping ^c,d   Hien, Tran Tinh ^g   Farrar, Jeremy J ^f,i,j   Aderem, Alan ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

^d Enodar Biologic Corporation   (United States)

^e OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^f Hospital for Tropical Diseases

^g Pham Ngoc Thach Hospital   (Viet Nam)

^h Hung Vuong Hospital   (Viet Nam)

ⁱ UNIVERSITY OF OXFORD   (United Kingdom)

^j LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROTEIN TIRAP; TOLL LIKE RECEPTOR 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; CRANIAL NERVE PARALYSIS; CYTOKINE PRODUCTION; FEMALE; GENE FREQUENCY; GENOTYPE; HEMIPLEGIA; HOST SUSCEPTIBILITY; HUMAN; HUMAN TISSUE; IMMUNOPATHOGENESIS; INFECTION SENSITIVITY; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN DOMAIN; SINGLE NUCLEOTIDE POLYMORPHISM; TUBERCULOUS MENINGITIS; UMBILICAL CORD BLOOD; VIET NAM;

EID: 33749586453     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/507907     Document Type: Article

References (49)

1. Small PM, Fujiwara PI. Management of tuberculosis in the United States. N Engl J Med 2001; 345:189-200.
2. Thwaites G, Chau TT, Mai NT, Drobniewski F, McAdam K, Farrar J. Tuberculous meningitis. J Neurol Neurosurg Psychiatry 2000; 68:289-99.
3. Cooke GS, Hill AV. Genetics of susceptibility to human infectious disease. Nat Rev Genet 2001; 2:967-77.
4. Casanova JL, Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol 2002; 20:581-620.
5. Bellamy R, Ruwende C, Corrah T, et al. Tuberculosis and chronic hepatitis B virus infection in Africans and variation in the vitamin D receptor gene. J Infect Dis 1999; 179:721-4.
6. Wilkinson R, Llewelyn M, Toossi Z, et al. Influence of vitamin D receptor and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study. Lancet 2000; 355:618-21.
7. Comstock GW. Tuberculosis in twins: a re-analysis of the Prophit survey. Am Rev Respir Dis 1978; 117:621-4.
8. Malik S, Schurr E. Genetic susceptibility to tuberculosis. Clin Chem Lab Med 2002; 40:863-8.
9. Newport MJ, Nejentsev S. Genetics of susceptibility to tuberculosis in humans. Monaldi Arch Chest Dis 2004; 61:102-11.
10. Blackwell JM, Goswami T, Evans CA, et al. SLC11AI (formerly NRAMP1) and disease resistance. Cell Microbiol 2001; 3:773-84.
11. Bellamy R. Genetic susceptibility to tuberculosis. Clin Chest Med 2005; 26:233-46.
12. Cook DN, Pisetsky DS, Schwartz DA. Toll-like receptors in the pathogenesis of human disease. Nat Immunol 2004; 5:975-9.
13. Picard C, Puel A, Bonnet M, et al. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 2003; 299:2076-9.
14. Hawn TR, Verbon A, Lettinga KD, et al. A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J Exp Med 2003; 198:1563-72.
15. Hawn TR, Verbon A, Janer M, Zhao LP, Beutler B, Aderem A. Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc Natl Acad Sci USA 2005; 102:2487-9.
16. Aderem A, Ulevitch RJ. Toll-like receptors in the induction of the innate immune response. Nature 2000; 406:782-7.
17. Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4:499-511.
18. Janeway CA Jr, Medzhitov R. Innate immune recognition. Annu Rev Immunol 2002; 20:197-216.
19. Heldwein KA, Fenton MJ. The role of Toll-like receptors in immunity against mycobacterial infection. Microbes Infect 2002; 4:937-44.
20. Underbill DM, Ozinsky A, Smith KD, Aderem A. Toll-like receptor-2 mediates mycobacteria-induced pro-inflammatory signaling in macrophages. Proc Nat Acad Sci USA 1999; 96:14459-63.
21. Brightbill HD, Libraty DH, Krutzik SR, et al. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 1999; 285:732-6.
22. Means TK, Wang S, Lien E, Yoshimura A, Golenbock DT, Fenton MJ. Human Toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. J Immunol 1999; 163:3920-7.
23. Bochud PY, Hawn TR, Aderem A. Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling. J Immunol 2003; 170:3451-4.
24. Krutzik SR, Ochoa MT, Sieling PA, et al. Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nat Med 2003; 9:525-32.
25. Stenger S, Modlin RL. Control of Mycobacterium tuberculosis through mammalian Toll-like receptors. Curr Opin Immunol 2002; 14:452-7.
26. Fitzgerald KA, Palsson-McDermott EM, Bowie AG, et al. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 2001; 413:78-83.
27. Horng T, Barton GM, Flaveli RA, Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 2002; 420:329-33.
28. McGettrick AF, O'Neill LA. The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. Mol Immunol 2004; 41:577-82.
29. Yamamoto M, Sato S, Hemmi H, et al. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 2002; 420:324-9.
30. Thwaites GE, Nguyen DB, Nguyen HD, et al. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med 2004; 351:1741-51.
31. Thwaites GE, Simmons CP, Than Ha Quyen N, et al. Pathophysiology and prognosis in Vietnamese adults with tuberculous meningitis. J Infect Dis 2003; 188:1105-15.
32. Gordon D, Abajian C, Green P. CONSED: a graphical tool for sequence finishing. Genome Res 1998; 8:195-202.
33. Storm N, Darnhofer-Patel B, van den Boom D, Rodi CP. MALDI-TOF mass spectrometry-based SNP genotyping. Methods Mol Biol 2003; 212:241-62.
34. Hawn TR, Wu H, Grossman JM, Hahn BH, Tsao BP, Aderem A. A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus. Proc Natl Acad Sci USA 2005; 102:10593-7.
35. Hawn TR, Ozinsky A, Williams LM, et al. Hyper-IgE syndrome is not associated with defects in several candidate toll-like receptor pathway genes. Hum Immunol 2005; 66:842-7.
36. Mander AP. Haplotype analysis in population-based association studies. Stata J 2001; 1:58-75.
37. Simmons CP, Thwaites GE, Quyen NT, et al. Pretreatment intracerebral and peripheral blood immune responses in Vietnamese adults with tuberculous meningitis: diagnostic value and relationship to disease severity and outcome. J Immunol 2006; 176:2007-14.
38. Bellamy R, Ruwende C, Corrah T, McAdam K, Whittle H, Hill A. Variations in the NRAMP1 gene and susceptibility to tuberculosis in West Africans. N Engl J Med 1998; 338:640-4.
39. de March-Ayuela P. Trend in tuberculous meningitis in Barcelona in children aged 0-4 years: correlation with the annual risk of tuberculous infection. Tuber Lung Dis 1994; 75:423-8.
40. Styblo K, Meijer J, Sutherland I. Tuberculosis Surveillance Research Unit report no. 1: the transmission of tubercle bacilli; its trend in a human population. Bull Int Union Tuberc 1969; 42:5-104.
41. United Nations Children's Fund (UNICEF). The state of the world's children 2006. New York: UNICEF, 2005.
42. Ackerman H, Usen S, Jallow M, Sisay-Joof F, Finder M, Kwiatkowski DP. A comparison of case-control and family-based association methods: the example of sickle-cell and malaria. Ann Hum Genet 2005; 69:559-65.
43. Koch O, Awomoyi A, Usen S, et al. IFNGR1 gene promoter polymorphisms and susceptibility to cerebral malaria. J Infect Dis 2002; 185:1684-7.
44. Roy S, Knox K, Segal S, et al. MBL genotype and risk of invasive pneumococcal disease: a case-control study. Lancet 2002; 359:1569-73.
45. Takeda K, Kaisho T, Akira S. Toll-like receptors. Annu Rev Immunol 2003; 21:335-76.
46. Quesniaux V, Fremond C, Jacobs M, et al. Toll-like receptor pathways in the immune responses to mycobacteria. Microbes Infect 2004; 6:946-59.
47. Ogus AC, Yoldas B, Ozdemir T, et al. The Arg753GLn polymorphism of the human Toll-like receptor 2 gene in tuberculosis disease. Eur Respir J 2004; 23:219-23.
48. Rossouw M, Nel HJ, Cooke GS, van Helden PD, Hoal EG. Association between tuberculosis and a polymorphic NFkappaB binding site in the interferon gamma gene. Lancet 2003; 361:1871-2.
49. Hoal-Van Helden EG, Epstein J, Victor TC, et al. Mannose-binding protein B allele confers protection against tuberculous meningitis. Pediatr Res 1999; 45:459-64.