Diabetes increases p53-mediated apoptosis following ischemia

Plastic and Reconstructive Surgery

Volumn 121, Issue 4, 2008, Pages 1135-1143

  Jazayeri, Leila ^a   Callaghan, Matthew J ^a   Grogan, Raymon H ^a   Hamou, Cynthia D ^a   Thanik, Vishal ^a   Ingraham, Christopher R ^a   Capell, Brian C ^a   Pelo, Catherine R ^a   Gurtner, Geoffrey C ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; SMALL INTERFERING RNA; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE MODEL; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; ISCHEMIA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; SKIN FIBROBLAST; SOFT TISSUE; STREPTOZOCIN DIABETES; WILD TYPE; ANIMAL; CELL CULTURE; EXPERIMENTAL DIABETES MELLITUS; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; ISCHEMIA; MICE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 42949093136     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000302499.18738.c2     Document Type: Article

References (43)

1. Lee, S. C., and Pervaiz, S. Apoptosis in the pathophysiology of diabetes mellitus. Int. J. Biochem. Cell Biol. 39: 497, 2007.
2. Sheu, J. J., Chang, L. T., Chiang, C. H., et al. Impact of diabetes on cardiomyocyte apoptosis and connexin43 gap junction integrity. Int. Heart J. 48: 233, 2007.
3. Vincent, A. M., McLean, L. L., Backus, C., et al. Short-term hyperglycemia produces oxidative damage and apoptosis in neurons. F.A.S.E.B. J. 19: 638, 2005.
4. Yang, R., Liu, H., and Chaqour, B. Matrix metalloproteinase-2 (MMP-2) expression and apoptogenic activity in retinal pericytes: Implications in diabetic retinopathy. Ann. N. Y. Acad. Sci. 1103: 196, 2007.
5. Baumgartner-Parzer, S. M., Wagner, L., Pettermann, M., et al. High-glucose-triggered apoptosis in cultured endothelial cells. Diabetes 44: 1323, 1995.
6. Quagliaro, L., Piconi, L., Assaloni, R., et al. Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: The role of protein kinase C and NAD(P)H-oxidase activation. Diabetes 52: 2795, 2003.
7. Kerr, J. F., Wyllie, A. H., and Currie, A. R. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26: 239, 1972.
8. McClintock, D. S., Santore, M. T., Lee, V. Y., et al. Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death. Mol. Cell. Biol. 22: 94, 2002.
9. Wyllie, A. H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555, 1980.
10. van de Schepop, H. A., de Jong, J. S., van Diest, P. J., et al. Counting of apoptotic cells: A methodological study in invasive breast cancer. Clin. Mol. Pathol. 49: M214, 1996.
11. Gross, A., Yin, X. M., Wang, K., et al. Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J. Biol. Chem. 274: 1156, 1999.
12. Wei, M. C., Zong, W. X., Cheng, E. H., et al. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 292: 727, 2001.
13. Fiordaliso, F., Leri, A., Cesselli, D., et al. Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death. Diabetes 50: 2363, 2001.
14. Centers for Disease Control and Prevention (CDC). Diabetes-related amputations of lower extremities in the Medicare population: Minnesota, 1993-1995. M.M.W.R. Morb. Mortal. Wkly. Rep. 47: 649, 1998.
15. Martin, A., Komada, M. R., and Sane, D. C. Abnormal angiogenesis in diabetes mellitus. Med. Res. Rev. 23: 117, 2003.
16. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N. Engl. J. Med. 329: 977, 1993.
17. Abaci, A., Oguzhan, A., Kahraman, S., et al. Effect of diabetes mellitus on formation of coronary collateral vessels. Circulation 99: 2239, 1999.
18. Aragones, J., Jones, D. R., Martin, S., et al. Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension. J. Biol. Chem. 276: 10548, 2001.
19. Basu, S., and Kolesnick, R. Stress signals for apoptosis: Ceramide and c-Jun kinase. Oncogene 17: 3277, 1998.
20. Harris, A. L. Hypoxia: A key regulatory factor in tumour growth. Nat. Rev. 2: 38, 2002.
21. Saikumar, P., Dong, Z., Patel, Y., et al. Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury. Oncogene 17: 3401, 1998.
22. Slee, E. A., O'Connor, D. J., and Lu, X. To die or not to die: How does p53 decide? Oncogene 23: 2809, 2004.
23. Ortega-Camarillo, C., Guzman-Grenfell, A. M., Garcia-Macedo, R., et al. Hyperglycemia induces apoptosis and p53 mobilization to mitochondria in RINm5F cells. Mol. Cell. Biochem. 281: 163, 2006.
24. Keim, A. L., Chi, M. M., and Moley, K. H. Hyperglycemia-induced apoptotic cell death in the mouse blastocyst is dependent on expression of p53. Mol. Reprod. Dev. 60: 214, 2001.
25. Suh, K. S., Nam, Y. H., Ahn, Y. M., et al. Effect of Scutellariae radix extract on the high glucose-induced apoptosis in cultured vascular endothelial cells. Biol. Pharm. Bull. 26: 1629, 2003.
26. Giaccia, A. J., Simon, M. C., and Johnson, R. The biology of hypoxia: The role of oxygen sensing in development, normal function, and disease. Genes Dev. 18: 2183, 2004.
27. McEvoy, R. C., Andersson, J., Sandler, S., et al. Multiple low-dose streptozotocin-induced diabetes in the mouse: Evidence for stimulation of a cytotoxic cellular immune response against an insulin-producing beta cell line. J. Clin. Invest. 74: 715, 1984.
28. Ceradini, D. J., Kulkarni, A. R., Callaghan, M. J., et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat. Med. 10: 858, 2004.
29. Peiro, C., Lafuente, N., Matesanz, N., et al. High glucose induces cell death of cultured human aortic smooth muscle cells through the formation of hydrogen peroxide. Br. J. Pharmacol. 133: 967, 2001.
30. Hammond, E. M., and Giaccia, A. J. The role of p53 in hypoxia-induced apoptosis. Biochem. Biophys. Res. Commun. 331: 718, 2005.
31. Drake, C. J., LaRue, A., Ferrara, N., et al. VEGF regulates cell behavior during vasculogenesis. Dev. Biol. 224: 178, 2000.
32. Chou, E., Suzuma, I., Way, K. J., et al. Decreased cardiac expression of vascular endothelial growth factor and its receptors in insulin-resistant and diabetic states: A possible explanation for impaired collateral formation in cardiac tissue. Circulation 105: 373, 2002.
33. Forsythe, J. A., Jiang, B. H., Iyer, N. V., et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 16: 4604, 1996.
34. Frank, S., Hubner, G., Breier, G., et al. Regulation of vascular endothelial growth factor expression in cultured keratinocytes: Implications for normal and impaired wound healing. J. Biol. Chem. 270: 12607, 1995.
35. Goova, M. T., Li, J., Kislinger, T., et al. Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice. Am. J. Pathol. 159: 513, 2001.
36. Lerman, O. Z., Galiano, R. D., Armour, M., et al. Cellular dysfunction in the diabetic fibroblast: Impairment in migration, vascular endothelial growth factor production, and response to hypoxia. Am. J. Pathol. 162: 303, 2003.
37. Rivard, A., Silver, M., Chen, D., et al. Rescue of diabetes-related impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. Am. J. Pathol. 154: 355, 1999.
38. Hehenberger, K., Heilborn, J. D., Brismar, K., et al. Inhibited proliferation of fibroblasts derived from chronic diabetic wounds and normal dermal fibroblasts treated with high glucose is associated with increased formation of l-lactate. Wound Repair Regen. 6: 135, 1998.
39. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. N. Engl. J. Med. 342: 381, 2000.
40. Engerman, R. L., and Kern, T. S. Progression of incipient diabetic retinopathy during good glycemic control. Diabetes 36: 808, 1987.
41. Brownlee, M. Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813, 2001.
42. Liu, G., Wong-Staal, F., and Li, Q. X. Development of new RNAi therapeutics. Histol. Histopathol. 22: 211, 2007.
43. Chao, C., Saito, S., Anderson, C. W., et al. Phosphorylation of murine p53 at ser-18 regulates the p53 responses to DNA damage. Proc. Natl. Acad. Sci. U.S.A. 97: 11936, 2000.