Environment and endocrinology: The case of thyroidology

Annales d'Endocrinologie

Volumn 69, Issue 2, 2008, Pages 116-122

  Kohrle J ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Cancer; Deficiency; Deiodinase; Endocrine disrupter; Flavonoid; Goiter; Hormone; Iodine; Isoflavonoid; Phytosteroid; Thyroid; Thyroperoxidase; Transthyretin

Indexed keywords

COSMETIC; ENDOCRINE DISRUPTOR; PESTICIDE; PLASTICIZER; PREALBUMIN; SODIUM IODIDE SYMPORTER; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROID PEROXIDASE;

ARTICLE; DEVELOPMENTAL DISORDER; DIET; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; GROWTH DISORDER; HUMAN; HYPOTHYROIDISM; IODINE DEFICIENCY; THYROID DISEASE; THYROID PAPILLARY CARCINOMA;

ANIMALS; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; HUMANS; THYROID DISEASES; THYROID GLAND; THYROID HORMONES;

EID: 42749087028     PISSN: 00034266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ando.2008.02.008     Document Type: Article

References (81)

1. Zimmermann M.B. The adverse effects of mild-to-moderate iodine deficiency during pregnancy and childhood: a review. Thyroid 17 (2007) 829-835
2. Coindet, J. F. (1820) Découverte d'un nouveau remède contre le goître. Ann. Chim. Phys. 15(Ser. 2):49-59.
3. Kendall E.C. The isolation in crystalline form of the compound containing iodine which occurs in the thyroid: its chemical nature and physiological activity. Trans Assoc Am Physicians 30 (1915) 420-449
4. Harington C.R. Chemistry of thyroxine. Isolation of thyroxine from the thyroid gland. Biochem J 20 (1926) 293-299
5. Magnus-Levy A. Ueber den respiratorischen Gaswechsel unter dem Einfluss der Thyreoidea sowie unter verschiedenen pathologischen Zustaenden. Berliner Klinische Wochenschrift 30 (1895) 650-652
6. Schmutzler C., Gotthardt I., Hofmann P.J., Radovic B., Kovacs G., Stemmler L., et al. Endocrine disruptors and the thyroid gland-a combined in vitro and in vivo analysis of potential new biomarkers. Environ Health Perspect 115 Suppl. 1 (2007) 77-83
7. Richardson S.J., Lemkine G.F., Alfama G., Hassani Z., and Demeneix B.A. Cell division and apoptosis in the adult neural stem cell niche are differentially affected in transthyretin null mice. Neurosci Lett 421 (2007) 234-238
8. Reed H.L., D'Alesandro M.M., Kowalski K.R., and Homer L.D. Multiple cold air exposures change oral triiodothyronine kinetics in normal men. Am J Physiol 263 (1992) E85-E93
9. Silva J.E. Thermogenic mechanisms and their hormonal regulation. Physiol Rev 86 (2006) 435-464
10. Burdock G.A., Soni M.G., and Carabin I.G. Evaluation of health aspects of kojic acid in food. Regul Toxicol Pharmacol 33 (2001) 80-101
11. Tamura T., Mitsumori K., Totsuka Y., Wakabayashi K., Kido R., Kasai H., et al. Absence of in vivo genotoxic potential and tumor initiation activity of kojic acid in the rat thyroid. Toxicology 222 (2006) 213-224
12. Tan S.W., and Zoeller R.T. Integrating basic research on thyroid hormone action into screening and testing programs for thyroid disruptors. Crit Rev Toxicol 37 (2007) 5-10
13. Zoeller R.T. Environmental chemicals impacting the thyroid: targets and consequences. Thyroid 17 (2007) 811-817
14. Allaerts W., and Vankelecom H. History and perspectives of pituitary folliculo-stellate cell research. Eur J Endocrinol 153 (2005) 1-12
15. Brokken L.J., Bakker O., Wiersinga W.M., and Prummel M.F. Functional thyrotropin receptor expression in the pituitary folliculo-stellate cell line TtT/GF. Exp Clin Endocrinol Diabetes 113 (2005) 13-20
16. Herkenham M. Folliculo-Stellate (FS) cells of the anterior aituitary mediate interactions between the endocrine and immune systems. Endocrinology 146 (2005) 33-34
17. Radovic B., Mentrup B., and Kohrle J. Genistein and other soya isoflavones are potent ligands for transthyretin in serum and cerebrospinal fluid. Br J Nutr 95 (2006) 1171-1176
18. Bruce B., Messina M., and Spiller G.A. Isoflavone supplements do not affect thyroid function in iodine-replete postmenopausal women. J Med Food 6 (2003) 309-316
19. Dillingham B.L., McVeigh B.L., Lampe J.W., and Duncan A.M. Soy protein isolates of varied isoflavone content do not influence serum thyroid hormones in healthy young men. Thyroid 17 (2007) 131-137
20. Doerge D.R., and Sheehan D.M. Goitrogenic and estrogenic activity of soy isoflavones. Environ Health Perspect 110 Suppl. 3 (2002) 349-353
21. Middlesworth L.V. Thyroxine excretion, a possible cause of goiter. Endocrinology 61 (1957) 570-573
22. Ripp J.A. Soybean-induced goiter. Am J Dis Child 102 (1961) 106-109
23. Shepard T.H., Pyne G.E., Kirschvink J.F., and McLean C.M. Soybean goiter. N Engl J Med 262 (1960) 1099-1103
24. Suwa J., Koyanagi T., and Kimura S. Studies on soybean factors which produced goiter in rats. J Nutr Sci Vitaminol 25 (1979) 309-315 [Tokyo]
25. Köhrle J. Low dose competition of flavonoids with endogenous thyroid transport proteins: potential relevance to the thyroid hormone axis. Functional food: safety aspects, symposium Forschungsberichte (DFG) Deutsche Forschungsgemeinschaft. Senate Commission on Food Safety SKLM (2004), Wiley-VCH Verlag 112-137
26. Fujimoto N., Watanabe H., Nakatani T., Roy G., and Ito A. Induction of thyroid tumours in (C57BL/6N × C3H/N)F1 mice by oral administration of kojic acid. Food Chem Toxicol 36 (1998) 697-703
27. Higa Y., Ohkubo A., Kitajima S., Hatori A., and Kariya K. Studies on thyroid function in rats subjected to repeated oral administration with kojic acid. J Toxicol Sci 25 (2000) 167-175
28. Köhrle J., Fang S.L., Yang Y., Irmscher K., Hesch R.D., Pino S., et al. Rapid effects of the flavonoid EMD 21388 on serum thyroid hormone binding and thyrotropin regulation in the rat. Endocrinology 125 (1989) 532-537
29. Abend S.L., Fang S.L., Alex S., Braverman L.E., and Leonard J.L. Rapid alteration in circulating free thyroxine modulates pituitary type II 5′deiodinase and basal thyrotropin secretion in the rat. J Clin Invest 88 (1991) 898-903
30. Pedraza P., Calvo R., Obregón M.J., Asunción M., del Rey F.E., and de Escobar G.M. Displacement of T4 from transthyretin by the synthetic flavonoid EMD 21388 results in increased production of T3 from T4 in rat dams and fetuses. Endocrinology 137 (1996) 4902-4914
31. Schröder-van der Elst J., Van der Heide D., and Köhrle J. In vivo effects of flavonoid EMD 21388 on thyroid hormone secretion and metabolism in the rat. Am J Physiol 261 (1991) E227-E232
32. Schröder van der Elst J.P., Van der Heide D., Rokos H., Köhrle J., and Morreale de Escobar G. Different tissue distribution, elimination, and kinetics of thyroxine and its conformational analog, the synthetic flavonoid EMD 49209 in the rat. Endocrinology 138 (1997) 79-84
33. Schmutzler C., Hamann I., Hofmann P.J., Kovacs G., Stemmler L., Mentrup B., et al. Endocrine active compounds affect thyrotropin and thyroid hormone levels in serum as well as endpoints of thyroid hormone action in liver, heart and kidney. Toxicology 205 (2004) 95-102
34. Schmutzler C., Bacinski A., Gotthardt I., Huhne K., Ambrugger P., Klammer H., et al. The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase. Endocrinology 148 (2007) 2835-2844
35. Hamann I., Seidlova-Wuttke D., Wuttke W., and Kohrle J. Effects of isoflavonoids and other plant-derived compounds on the hypothalamus-pituitary-thyroid hormone axis. Maturitas 55S (2006) S14-S25
36. Jarry H., Christoffel J., Rimoldi G., Koch L., and Wuttke W. Multi-organic endocrine disrupting activity of the UV screen benzophenone 2 (BP2) in ovariectomized adult rats after 5 days treatment. Toxicology 205 (2004) 87-93
37. Klammer H., Schlecht C., Wuttke W., Schmutzler C., Gotthardt I., Kohrle J., et al. Effects of a 5-day treatment with the UV-filter octyl-methoxycinnamate (OMC) on the function of the hypothalamo-pituitary-thyroid function in rats. Toxicology 238 (2007) 192-199
38. Seidlova-Wuttke D., Jarry H., Christoffel J., Rimoldi G., and Wuttke W. Effects of bisphenol-A (BPA), dibutylphtalate (DBP), benzophenone-2 (BP2), procymidone (Proc), and linurone (Lin) on fat tissue, a variety of hormones and metabolic parameters: A 3 months comparison with effects of estradiol (E2) in ovariectomized (ovx) rats. Toxicology 213 (2005) 13-24
39. Wuttke W., Jarry H., and Seidlova-Wuttke D. Isoflavones - safe food additives or dangerous drugs?. Ageing Res Rev 6 (2007) 150-188
40. Hagmar L. Polychlorinated biphenyls and thyroid status in humans: a review. Thyroid 13 (2003) 1021-1028
41. Vansell N.R., Muppidi J.R., Habeebu S.M., and Klaassen C.D. Promotion of thyroid tumors in rats by Pregnenolone-16{alpha}-Carbonitrile (PCN) and polychlorinated biphenyl (PCB). Toxicol Sci 81 (2004) 50-59
42. Takagi H, Mitsumori K, Onodera H, Nasu M, Tamura T, Yasuhara K, et al. Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats. Cancer Lett. 2002;178 (1):1-9.
43. Dohan O., Portulano C., Basquin C., Reyna-Neyra A., Amzel L.M., and Carrasco N. The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate. Proc Natl Acad Sci U S A 104 (2007) 20250-20255
44. Braverman L.E. Clinical studies of exposure to perchlorate in the United States. Thyroid 17 (2007) 819-822
45. Braverman L.E., Pearce E.N., He X., Pino S., Seeley M., Beck B., et al. Effects of six months of daily low-dose perchlorate exposure on thyroid function in healthy volunteers. J Clin Endocrinol Metab 91 (2006) 2721-2724
46. De Groef B., Decallonne B.R., Van der Geyten S., Darras V.M., and Bouillon R. Perchlorate versus other environmental sodium/iodide symporter inhibitors: potential thyroid-related health effects. Eur J Endocrinol 155 (2006) 17-25
47. Murray CW, Egan SK, Kim H, Beru N & Bolger PM. US Food and drug administration's total diet study: dietary intake of perchlorate and iodine. J Expo Sci Environ Epidemiol. [In press] 2008 Jan 2 [Epub ahead of print].
48. Auf'mkolk M., Ingbar J.C., Amir S.M., Winterhoff H., Sourgens H., Hesch R.D., et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology 115 (1984) 527-534
49. Auf'mkolk M., Amir S.M., Kubota K., and Ingbar S.H. The active principles of plant extracts with antithyrotropic activity: oxidation products of derivatives of 3,4-dihydroxycinnamic acid. Endocrinology 116 (1985) 1677-1686
50. Auf'mkolk M., Ingbar J.C., Kubota K., Amir S.M., and Ingbar S.H. Extracts and auto-oxidized constituents of certain plants inhibit the receptor-binding and the biological activity of Graves' immunoglobulins. Endocrinology 116 (1985) 1687-1693
51. Gaitan E. Flavonoids and the thyroid. Nutrition 12 (1996) 127-129
52. Giuliani C., Noguchi Y., Harii N., Napolitano G., Tatone D., Bucci I., et al. The flavonoid quercetin regulates growth and gene expression in rat FRTL-5 thyroid cells. Endocrinology 149 (2008) 84-92
53. Cunha G.C., and van Ravenzwaay B. Evaluation of mechanisms inducing thyroid toxicity and the ability of the enhanced OECD Test Guideline 407 to detect these changes. Arch Toxicol 79 (2005) 390-405
54. Schuur A.G., Brouwer A., Bergman A., Coughtrie M.W.H., and Visser T.J. Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls. Chem Biol Interact 109 (1998) 293-297
55. Brouwer A., Morse D.C., Lans M.C., Schuur A.G., Murk A.J., Klasson-Wehler E., et al. Interactions of persistent environmental organohalogens with the thyroid hormone system: mechanisms and possible consequences for animal and human health. Toxicology and Industrial Health 14 (1998) 59-84
56. Morse D.C., Groen D., Veerman M., Vanamerongen C.J., Koeter H.B.W.M., Vanprooije A.E.S., et al. Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats. Toxicology and Applied Pharmacology 122 (1993) 27-33
57. Hood A., and Klaassen C.D. Differential effects of microsomal enzyme inducers on in vitro thyroxine (T4) and triiodothyronine (T3) glucuronidation. Toxicol Sci 55 (2000) 78-84
58. Hallgren S., and Darnerud P.O. Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats-testing interactions and mechanisms for thyroid hormone effects. Toxicology 177 (2002) 227-243
59. Kato Y., Haraguchi K., Yamazaki T., Ito Y., Miyajima S., Nemoto K., et al. Effects of polychlorinated biphenyls, Kanechlor-500, on serum thyroid hormone levels in rats and mice. Toxicol Sci 72 (2003) 235-241
60. Qatanani M., Zhang J., and Moore D.D. Role of the constitutive androstane receptor in xenobiotic-induced thyroid hormone metabolism. Endocrinology 146 (2005) 995-1002
61. Cody V, Köhrle J, Auf'mkolk M, Hesch RD. Structure-activity relationships of flavonoid deiodinase inhibitors and enzyme active site models. Prog Clin Biol Res 1986;213:373-82.
62. Köhrle J. Flavonoids as a risk factor for goiter and hypothyroidism. in: The thyroid and environment. Peter F, Wiersinga W, Hostalek U (eds). 2000, Schattauer, Stuttgart; Proceedings of the Merck European Thyroid Symposium Budapest 2000, June 22-25, 2000, 41-63.
63. Spanka M., Hesch R.-D., Irmscher K., and Köhrle J. 5′-Deiodination in rat hepatocytes: effects of specific flavonoid inhibitors. Endocrinology 126 (1990) 1660-1667
64. Schröder-Van der Elst J.P., Van der Heide D., and Versloot P.M. Effects of EMD 21388 on the kinetics of T4 and T3 (TH) in the female rat. J Endocrinol Invest 17 (1994) 19
65. Fini J.B., Le Mevel S., Turque N., Palmier K., Zalko D., Cravedi J.P., et al. An in vivo multiwell-based fluorescent screen for monitoring vertebrate thyroid hormone disruption. Environ Sci Technol 41 (2007) 5908-5914
66. Iwamuro S., Yamada M., Kato M., and Kikuyama S. Effects of bisphenol A on thyroid hormone-dependent up-regulation of thyroid hormone receptor [alpha] and [beta] and down-regulation of retinoid X receptor [gamma] in Xenopus tail culture. Life Sciences 79 (2006) 2165-2171
67. Moriyama K., Tagami T., Akamizu T., Usui T., Saijo M., Kanamoto N., et al. Thyroid hormone action is disrupted by bisphenol A as an antagonist. J Clin Endocrinol Metab 87 (2002) 5185-5190
68. Seiwa C., Nakahara J., Komiyama T., Katsu Y., Iguchi T., and Asou H. Bisphenol A exerts thyroid-hormone-like effects on mouse oligodendrocyte precursor cells. Neuroendocrinology 80 (2004) 21-30
69. Zoeller R.T., Bansal R., and Parris C. Bisphenol-A, an environmental contaminant that acts as a thyroid hormone receptor antagonist in vitro, increases serum thyroxine, and alters RC3/Neurogranin expression in the developing rat brain. Endocrinology 146 (2005) 607-612
70. Zoeller R.T. Environmental chemicals as thyroid hormone analogues: new studies indicate that thyroid hormone receptors are targets of industrial chemicals?. Mol Cell Endocrinol 242 (2005) 10-15
71. Schlumpf M, Durrer S, Faass O, Ehnes C, Fuetsch M, Gaille C, et al. Developmental toxicity of UV filters and environmental exposure: a review. Int J Androl., in press.
72. Radovic B., Schmutzler C., and Kohrle J. Xanthohumol stimulates iodide uptake in rat thyroid-derived FRTL-5 cells. Mol Nutr Food Res 49 (2005) 832-836
73. Wolff J. Perchlorate and the thyroid gland. Pharmacol Rev 50 (1998) 89-118
74. Arulmozhiraja S., Shiraishi F., Okumura T., Iida M., Takigami H., Edmonds J.S., et al. Structural requirements for the interaction of 91 hydroxylated polychlorinated biphenyls with estrogen and thyroid hormone receptors. Toxicol Sci 84 (2005) 49-62
75. Bogazzi F., Raggi F., Ultimieri F., Russo D., Campomori A., McKinney J.D., et al. Effects of a mixture of polychlorinated biphenyls (Aroclor 1254) on the transcriptional activity of thyroid hormone receptor. J Endocrinol Invest 26 (2003) 972-978
76. Chauhan K.R., Kodavanti P.R., and McKinney J.D. Assessing the role of ortho-substitution on polychlorinated biphenyl binding to transthyretin, a thyroxine transport protein. Toxicol Appl Pharmacol 162 (2000) 10-21
77. Chevrier J., Eskenazi B., Bradman A., Fenster L., and Barr D.B. Associations between prenatal exposure to polychlorinated biphenyls and neonatal thyroid-stimulating hormone levels in a Mexican-American population, Salinas Valley, California. Environ Health Perspect 115 (2007) 1490-1496
78. Zhou T., Taylor M.M., DeVito M.J., and Crofton K.M. Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption. Toxicol Sci 66 (2002) 105-116
79. Kuriyama S.N., Wanner A., Fidalgo-Neto A.A., Talsness C.E., Koerner W., and Chahoud I. Developmental exposure to low-dose PBDE-99: tissue distribution and thyroid hormone levels. Toxicology 242 (2007) 80-90
80. Tabb M.M., and Blumberg B. New modes of action for endocrine-disrupting chemicals. Mol Endocrinol 20 (2006) 475-482
81. Langer P., Tajtakova M., Kocan A., Petrik J., Koska J., Ksinantova L., et al. Thyroid ultrasound volume, structure and function after long-term high exposure of large population to polychlorinated biphenyls, pesticides and dioxin. Chemosphere 69 (2007) 118-127