메뉴 건너뛰기




Volumn 36, Issue 4, 2008, Pages 363-368

N-acetylcysteine derivative inhibits CD40-dependent proinflammatory properties of human pancreatic duct cells

Author keywords

CAPAN 2; CD40; Islet transplantation; NF B; Pancreatic duct cells; Type 1 diabetes mellitus

Indexed keywords

ACETYLCYSTEINE DERIVATIVE; CD40 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; NACYSTELYN; TUMOR NECROSIS FACTOR ALPHA;

EID: 42549144939     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e31815c75d4     Document Type: Article
Times cited : (5)

References (50)
  • 1
    • 0031841517 scopus 로고    scopus 로고
    • Extra-insular beta cells associated with ductules are frequent in adult human pancreas
    • Bouwens L, Pipeleers DG. Extra-insular beta cells associated with ductules are frequent in adult human pancreas. Diabetologia. 1998;41:629-633.
    • (1998) Diabetologia , vol.41 , pp. 629-633
    • Bouwens, L.1    Pipeleers, D.G.2
  • 2
    • 0030762472 scopus 로고    scopus 로고
    • Effect of interferon-gamma and glucose on major histocompatibility complex class I and class II expression by pancreatic beta- and non-beta-cells
    • Pavlovic D, van de Winkel M, van der Auwera B, et al. Effect of interferon-gamma and glucose on major histocompatibility complex class I and class II expression by pancreatic beta- and non-beta-cells. J Clin Endocrinol Metab. 1997;82:2329-2336.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2329-2336
    • Pavlovic, D.1    van de Winkel, M.2    van der Auwera, B.3
  • 3
    • 0032929766 scopus 로고    scopus 로고
    • Contribution of ductal cells to cytokine responses by human pancreatic islets
    • Pavlovic D, Chen MC, Bouwens L, et al. Contribution of ductal cells to cytokine responses by human pancreatic islets. Diabetes. 1999;48:29-33.
    • (1999) Diabetes , vol.48 , pp. 29-33
    • Pavlovic, D.1    Chen, M.C.2    Bouwens, L.3
  • 4
    • 0035129049 scopus 로고    scopus 로고
    • Role of pancreatic beta-cells in the process of beta-cell death
    • Pipeleers D, Hoorens A, Marichal-Pipeleers M, et al. Role of pancreatic beta-cells in the process of beta-cell death. Diabetes. 2001;50:(suppl 1):S52-S57.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Pipeleers, D.1    Hoorens, A.2    Marichal-Pipeleers, M.3
  • 5
    • 0030467497 scopus 로고    scopus 로고
    • Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation
    • Ling Z, Pipeleers DG. Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation. J Clin Invest. 1996;98:2805-2812.
    • (1996) J Clin Invest , vol.98 , pp. 2805-2812
    • Ling, Z.1    Pipeleers, D.G.2
  • 6
    • 6844239526 scopus 로고    scopus 로고
    • Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: Graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft
    • Keymeulen B, Ling Z, Gorus FK, et al. Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft. Diabetologia. 1998;41:452-459.
    • (1998) Diabetologia , vol.41 , pp. 452-459
    • Keymeulen, B.1    Ling, Z.2    Gorus, F.K.3
  • 7
    • 3142699932 scopus 로고    scopus 로고
    • Human pancreatic duct cells can produce tumor necrosis factor-α that damages neighbouring beta cells and activates dendritic cells
    • Movahedi B, Van de Casteele M, Caluwé N, et al. Human pancreatic duct cells can produce tumor necrosis factor-α that damages neighbouring beta cells and activates dendritic cells. Diabetologia. 2004;47:998-1008.
    • (2004) Diabetologia , vol.47 , pp. 998-1008
    • Movahedi, B.1    Van de Casteele, M.2    Caluwé, N.3
  • 8
    • 2442641694 scopus 로고    scopus 로고
    • CD40 expression on human pancreatic duct cells: Role in nuclear factor-kappa B activation and production of pro-inflammatory cytokines
    • Vosters O, Beuneu C, Nagy N, et al. CD40 expression on human pancreatic duct cells: role in nuclear factor-kappa B activation and production of pro-inflammatory cytokines. Diabetologia. 2004;47:660-668.
    • (2004) Diabetologia , vol.47 , pp. 660-668
    • Vosters, O.1    Beuneu, C.2    Nagy, N.3
  • 9
    • 0033765333 scopus 로고    scopus 로고
    • Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells
    • Woltman AM, de Haij S, Boonstra JG, et al. Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells. J Am Soc Nephrol. 2000;11:2044-2055.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 2044-2055
    • Woltman, A.M.1    de Haij, S.2    Boonstra, J.G.3
  • 10
    • 0034663954 scopus 로고    scopus 로고
    • Proinflammatory and Th2-derived cytokines modulate CD40-mediated expression of inflammatory mediators in airway epithelia: Implications for the role of epithelial CD40 in airway inflammation
    • Propst SM, Denson R, Rothstein E, et al. Proinflammatory and Th2-derived cytokines modulate CD40-mediated expression of inflammatory mediators in airway epithelia: implications for the role of epithelial CD40 in airway inflammation. J Immunol. 2000;165:2214-2221.
    • (2000) J Immunol , vol.165 , pp. 2214-2221
    • Propst, S.M.1    Denson, R.2    Rothstein, E.3
  • 11
    • 17944381918 scopus 로고    scopus 로고
    • CD40 activation-induced, Fas-dependent apoptosis and NF-kappaB/AP-1 signaling in human intrahepatic biliary epithelial cells
    • Afford SC, Ahmed-Choudhury J, Randhawa S et al. CD40 activation-induced, Fas-dependent apoptosis and NF-kappaB/AP-1 signaling in human intrahepatic biliary epithelial cells. FASEB J. 2001;15:2345-2354.
    • (2001) FASEB J , vol.15 , pp. 2345-2354
    • Afford, S.C.1    Ahmed-Choudhury, J.2    Randhawa, S.3
  • 12
    • 0037020065 scopus 로고    scopus 로고
    • CD40-mediated activation of NF-kappa B in airway epithelial cells
    • Propst SM, Estell K, Schwiebert LM. CD40-mediated activation of NF-kappa B in airway epithelial cells. J Biol Chem. 2002;277:37054-37063.
    • (2002) J Biol Chem , vol.277 , pp. 37054-37063
    • Propst, S.M.1    Estell, K.2    Schwiebert, L.M.3
  • 13
    • 0036740392 scopus 로고    scopus 로고
    • Production of inflammatory mediators by renal epithelial cells is insensitive to glucocorticoids
    • de Haij S, Woltman AM, Bakker AC, et al. Production of inflammatory mediators by renal epithelial cells is insensitive to glucocorticoids. Br J Pharmacol. 2002;137:197-204.
    • (2002) Br J Pharmacol , vol.137 , pp. 197-204
    • de Haij, S.1    Woltman, A.M.2    Bakker, A.C.3
  • 14
    • 0036553560 scopus 로고    scopus 로고
    • In vitro expression of fas and CD40 and induction of apoptosis in human cystic fibrosis airway epithelial cells
    • Amsellem C, Dirieu I, Chambe MT, et al. In vitro expression of fas and CD40 and induction of apoptosis in human cystic fibrosis airway epithelial cells. Respir Med. 2002;96:244-249.
    • (2002) Respir Med , vol.96 , pp. 244-249
    • Amsellem, C.1    Dirieu, I.2    Chambe, M.T.3
  • 15
    • 0028152658 scopus 로고
    • Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B
    • Berberich I, Shu GL, Clark EA. Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B. J Immunol. 1994;153:4357-4366.
    • (1994) J Immunol , vol.153 , pp. 4357-4366
    • Berberich, I.1    Shu, G.L.2    Clark, E.A.3
  • 16
    • 0030744132 scopus 로고    scopus 로고
    • Functions of CD40 on B cells, dendritic cells and other cells
    • van Kooten C, Banchereau J. Functions of CD40 on B cells, dendritic cells and other cells. Curr Opin Immunol. 1997;9:330-337.
    • (1997) Curr Opin Immunol , vol.9 , pp. 330-337
    • van Kooten, C.1    Banchereau, J.2
  • 18
    • 0032484987 scopus 로고    scopus 로고
    • CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
    • Henn V, Slupsky JR, Grafe M, et al. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature. 1998;391:591-594.
    • (1998) Nature , vol.391 , pp. 591-594
    • Henn, V.1    Slupsky, J.R.2    Grafe, M.3
  • 19
    • 0037456735 scopus 로고    scopus 로고
    • CD40 ligand-assessing risk instead of damage?
    • Freedman JE. CD40 ligand-assessing risk instead of damage? N Engl J Med. 2003;348:1163-1165.
    • (2003) N Engl J Med , vol.348 , pp. 1163-1165
    • Freedman, J.E.1
  • 20
    • 0037456769 scopus 로고    scopus 로고
    • Soluble CD40 ligand in acute coronary syndromes
    • Heeschen C, Dimmeler S, Hamm CW, et al. Soluble CD40 ligand in acute coronary syndromes. N Engl J Med. 2003;348:1104-1111.
    • (2003) N Engl J Med , vol.348 , pp. 1104-1111
    • Heeschen, C.1    Dimmeler, S.2    Hamm, C.W.3
  • 21
    • 0028033310 scopus 로고
    • Activation of human dendritic cells through CD40 cross-linking
    • Caux C, Massacrier C, Vanbervliet B, et al. Activation of human dendritic cells through CD40 cross-linking. J Exp Med. 1994;180:1263-1272.
    • (1994) J Exp Med , vol.180 , pp. 1263-1272
    • Caux, C.1    Massacrier, C.2    Vanbervliet, B.3
  • 22
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • Grewal IS, Flavell RA. CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol. 1998;16:111-135.
    • (1998) Annu Rev Immunol , vol.16 , pp. 111-135
    • Grewal, I.S.1    Flavell, R.A.2
  • 23
    • 0036604277 scopus 로고    scopus 로고
    • CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB
    • O'Sullivan BJ, Thomas R. CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB. J Immunol. 2002;168:5491-5498.
    • (2002) J Immunol , vol.168 , pp. 5491-5498
    • O'Sullivan, B.J.1    Thomas, R.2
  • 24
    • 0036201121 scopus 로고    scopus 로고
    • CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells
    • Homann D, Jahreis A, Wolfe T, et al. CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells. Immunity. 2002;16:403-415.
    • (2002) Immunity , vol.16 , pp. 403-415
    • Homann, D.1    Jahreis, A.2    Wolfe, T.3
  • 25
    • 0036850826 scopus 로고    scopus 로고
    • Prevention of autoimmune diabetes in the DRBB rat by CD40/154 blockade
    • Moore WV, Chu W, Tong PY, et al. Prevention of autoimmune diabetes in the DRBB rat by CD40/154 blockade. J Autoimmun. 2002;19:139-145.
    • (2002) J Autoimmun , vol.19 , pp. 139-145
    • Moore, W.V.1    Chu, W.2    Tong, P.Y.3
  • 26
    • 0034956878 scopus 로고    scopus 로고
    • CD40 ligand-deficient mice are protected against cerulein-induced acute pancreatitis and pancreatitis- associated lung injury
    • Frossard JL, Kwak B, Chanson M, et al. CD40 ligand-deficient mice are protected against cerulein-induced acute pancreatitis and pancreatitis- associated lung injury. Gastroenterology. 2001;121:184-194.
    • (2001) Gastroenterology , vol.121 , pp. 184-194
    • Frossard, J.L.1    Kwak, B.2    Chanson, M.3
  • 27
    • 0031260625 scopus 로고    scopus 로고
    • Effect of the mucoactive drug nacystelyn on the respiratory burst of human blood polymorphonuclear neutrophils
    • Nagy AM, Vanderbist F, Parij N, et al. Effect of the mucoactive drug nacystelyn on the respiratory burst of human blood polymorphonuclear neutrophils. Pulm Pharmacol Ther. 1997;10:287-292.
    • (1997) Pulm Pharmacol Ther , vol.10 , pp. 287-292
    • Nagy, A.M.1    Vanderbist, F.2    Parij, N.3
  • 28
    • 0037166140 scopus 로고    scopus 로고
    • Inhibitory effects of thiol-containing drugs on erythrocyte oxidative damages investigated with an improved assay system
    • Vosters O, Nève J. Inhibitory effects of thiol-containing drugs on erythrocyte oxidative damages investigated with an improved assay system. Talanta. 2002;595-600.
    • (2002) Talanta , pp. 595-600
    • Vosters, O.1    Nève, J.2
  • 29
    • 0037087145 scopus 로고    scopus 로고
    • Nacystelyn inhibits oxidant-mediated interleukine-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells
    • Antonicelli F, Parmentier M, Drost EM, et al. Nacystelyn inhibits oxidant-mediated interleukine-8 expression and NF-kappaB nuclear binding in alveolar epithelial cells. Free Radic Biol Med. 2002;32:492-502.
    • (2002) Free Radic Biol Med , vol.32 , pp. 492-502
    • Antonicelli, F.1    Parmentier, M.2    Drost, E.M.3
  • 30
    • 0037442168 scopus 로고    scopus 로고
    • Dendritic cells exposed to nacystelyn are refractory to maturation and promote the emergence of alloreactive regulatory T cells
    • Vosters O, Nève J, De Wit D, et al. Dendritic cells exposed to nacystelyn are refractory to maturation and promote the emergence of alloreactive regulatory T cells. Transplantation. 2003;75:383-389.
    • (2003) Transplantation , vol.75 , pp. 383-389
    • Vosters, O.1    Nève, J.2    De Wit, D.3
  • 31
    • 0033106338 scopus 로고    scopus 로고
    • N-acetyl- L-cysteine inhibits primary human T cell responses at the dendritic cell level: Association with NF-κB inhibition
    • Verhasselt V, Vanden Berghe W, Vanderheyde N, et al. N-acetyl- L-cysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-κB inhibition. J Immunol. 1999;162:2569-2574.
    • (1999) J Immunol , vol.162 , pp. 2569-2574
    • Verhasselt, V.1    Vanden Berghe, W.2    Vanderheyde, N.3
  • 32
    • 34247216064 scopus 로고    scopus 로고
    • N-acetylcysteine derivative inhibits procoagulant activity of human islet cells
    • Beuneu C, Vosters O, Ling Z, et al. N-acetylcysteine derivative inhibits procoagulant activity of human islet cells. Diabetologia. 2007;50:343-347.
    • (2007) Diabetologia , vol.50 , pp. 343-347
    • Beuneu, C.1    Vosters, O.2    Ling, Z.3
  • 33
    • 0042572491 scopus 로고    scopus 로고
    • Netrin-1 expression in fetal and regenerating rat pancreas and its effect on the migration of human pancreatic duct and porcine islet precursor cells
    • De Breuck S, Lardon J, Rooman I, et al. Netrin-1 expression in fetal and regenerating rat pancreas and its effect on the migration of human pancreatic duct and porcine islet precursor cells. Diabetologia. 2003;46:926-933.
    • (2003) Diabetologia , vol.46 , pp. 926-933
    • De Breuck, S.1    Lardon, J.2    Rooman, I.3
  • 34
    • 0342742310 scopus 로고
    • Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B
    • Osborn L, Kunkel S, Nabel GJ. Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. Proc Natl Acad Sci U S A. 1989;86:2336-2340.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 2336-2340
    • Osborn, L.1    Kunkel, S.2    Nabel, G.J.3
  • 35
    • 0036499102 scopus 로고    scopus 로고
    • Analysis of spontaneous mRNA cytokine production in peripheral blood
    • Stordeur P, Zhou L, Goldman M. Analysis of spontaneous mRNA cytokine production in peripheral blood. J Immunol Methods. 2002;261:195-197.
    • (2002) J Immunol Methods , vol.261 , pp. 195-197
    • Stordeur, P.1    Zhou, L.2    Goldman, M.3
  • 36
    • 0037406607 scopus 로고    scopus 로고
    • Immune monitoring in whole blood using real-time PCR
    • Stordeur P, Zhou L, Byl B, et al. Immune monitoring in whole blood using real-time PCR. J Immunol Methods. 2003;276:69-77.
    • (2003) J Immunol Methods , vol.276 , pp. 69-77
    • Stordeur, P.1    Zhou, L.2    Byl, B.3
  • 37
    • 0028908832 scopus 로고
    • Posttranscriptional regulation of macrophage tissue factor expression by antioxidants
    • Brisseau G, Dackwin A, Cheung P, et al. Posttranscriptional regulation of macrophage tissue factor expression by antioxidants. Blood. 1995;85:1025-1035.
    • (1995) Blood , vol.85 , pp. 1025-1035
    • Brisseau, G.1    Dackwin, A.2    Cheung, P.3
  • 38
    • 0033625664 scopus 로고    scopus 로고
    • Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis
    • Ling Z, Van de Casteele M, Eizirik DL, et al. Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis. Diabetes. 2000;49:340-345.
    • (2000) Diabetes , vol.49 , pp. 340-345
    • Ling, Z.1    Van de Casteele, M.2    Eizirik, D.L.3
  • 39
    • 0036068246 scopus 로고    scopus 로고
    • Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production
    • Thomas HE, Darwiche R, Corbett JA, et al. Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production. Diabetes. 2002;51:311-316.
    • (2002) Diabetes , vol.51 , pp. 311-316
    • Thomas, H.E.1    Darwiche, R.2    Corbett, J.A.3
  • 40
    • 0041765716 scopus 로고    scopus 로고
    • Free radicals and the pathogenesis of type 1 diabetes: Beta-cell cytokine-mediated free radical generation via cyclooxygenase-2
    • Tabatabaie T, Vasquez-Weldon A, Moore DR, et al. Free radicals and the pathogenesis of type 1 diabetes: beta-cell cytokine-mediated free radical generation via cyclooxygenase-2. Diabetes. 2003;52:1994-1999.
    • (2003) Diabetes , vol.52 , pp. 1994-1999
    • Tabatabaie, T.1    Vasquez-Weldon, A.2    Moore, D.R.3
  • 41
    • 0027717934 scopus 로고
    • Inflammatory mediators and cytokines - new aspects of the pathophysiology and assessment of severity of acute pancreatitis?
    • Gross V, Leser HG, Heinisch A, et al. Inflammatory mediators and cytokines - new aspects of the pathophysiology and assessment of severity of acute pancreatitis? Hepatogastroenterology. 1993;40:522-530.
    • (1993) Hepatogastroenterology , vol.40 , pp. 522-530
    • Gross, V.1    Leser, H.G.2    Heinisch, A.3
  • 42
    • 0033623366 scopus 로고    scopus 로고
    • Suppression of NF-JB activation and cytokine production by N-acetylcysteine in pancreatic acinar cells
    • Kim H, Seo JY, Roh KH, et al. Suppression of NF-JB activation and cytokine production by N-acetylcysteine in pancreatic acinar cells. Free Radic Biol Med. 2000;29:674-683.
    • (2000) Free Radic Biol Med , vol.29 , pp. 674-683
    • Kim, H.1    Seo, J.Y.2    Roh, K.H.3
  • 43
    • 27944447238 scopus 로고    scopus 로고
    • Pro- and anti-inflammatory response of acinar cells during acute pancreatitis. Effect of N-acetyl cysteine
    • Ramudo L, Manso MA, Vicente S, et al. Pro- and anti-inflammatory response of acinar cells during acute pancreatitis. Effect of N-acetyl cysteine. Cytokine. 2005;32:125-131.
    • (2005) Cytokine , vol.32 , pp. 125-131
    • Ramudo, L.1    Manso, M.A.2    Vicente, S.3
  • 44
    • 0034101816 scopus 로고    scopus 로고
    • + T cells play an important role in acute experimental pancreatitis in mice
    • + T cells play an important role in acute experimental pancreatitis in mice. Gastroenterology. 2000;118:582-590.
    • (2000) Gastroenterology , vol.118 , pp. 582-590
    • Demols, A.1    Le Moine, O.2    Desalle, F.3
  • 45
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro AM, Lakey JRT, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000;343:230-238.
    • (2000) N Engl J Med , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.T.2    Ryan, E.A.3
  • 46
    • 33644649772 scopus 로고    scopus 로고
    • Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154
    • Xu H, Zhang X, Mannon RB, et al. Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154. J Clin Invest. 2006;116:769-774.
    • (2006) J Clin Invest , vol.116 , pp. 769-774
    • Xu, H.1    Zhang, X.2    Mannon, R.B.3
  • 47
    • 0033810263 scopus 로고    scopus 로고
    • Anti-CD154 (CD40L) prevents recurrence of diabetes in islet isografts in the DR-BB rat
    • Kover KL, Geng Z, Hess DM, et al. Anti-CD154 (CD40L) prevents recurrence of diabetes in islet isografts in the DR-BB rat. Diabetes. 2000;49:1666-1670.
    • (2000) Diabetes , vol.49 , pp. 1666-1670
    • Kover, K.L.1    Geng, Z.2    Hess, D.M.3
  • 48
    • 0037443412 scopus 로고    scopus 로고
    • Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance
    • Phillips NE, Markees TG, Mordes JP, et al. Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance. J Immunol. 2003;170:3015-3023.
    • (2003) J Immunol , vol.170 , pp. 3015-3023
    • Phillips, N.E.1    Markees, T.G.2    Mordes, J.P.3
  • 49
    • 33644829825 scopus 로고    scopus 로고
    • Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways
    • Cardona K, Korbutt GS, Milas Z, et al. Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways. Nat Med. 2006;12:304-306.
    • (2006) Nat Med , vol.12 , pp. 304-306
    • Cardona, K.1    Korbutt, G.S.2    Milas, Z.3
  • 50
    • 0037080947 scopus 로고    scopus 로고
    • The CD154-CD40 costimulatory pathway in transplantation
    • Yamada A, Sayegh MH. The CD154-CD40 costimulatory pathway in transplantation. Transplantation. 2002;73:S36-S39.
    • (2002) Transplantation , vol.73
    • Yamada, A.1    Sayegh, M.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.