Simvastatin reduces Chlamydophila pneumoniae-mediated histone modifications and gene expression in cultured human endothelial cells

Circulation Research

Volumn 102, Issue 8, 2008, Pages 888-895

  Schmeck, Bernd ^a   Beermann, Wiebke ^a   Dje N'Guessan, Philippe ^a   Hocke, Andreas C ^a   Opitz, Bastian ^a   Eitel, Julia ^a   Dinh, Quoc Thai ^a   Witzenrath, Martin ^a   Krüll, Matthias ^a   Suttorp, Norbert ^a   Hippenstiel, Stefan ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Chlamydophila pneumoniae; Cytokines; Endothelial cells; Histones; Statins

Indexed keywords

COLONY STIMULATING FACTOR 1; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTONE H3; HISTONE H4; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RNA POLYMERASE II; SIMVASTATIN; TRICHOSTATIN A; VORINOSTAT;

ACETYLATION; ARTICLE; BACTERIAL INFECTION; CELL CULTURE; CELL LINE; CELL VIABILITY; CHLAMYDOPHILA PNEUMONIAE; CHROMATIN IMMUNOPRECIPITATION; CYTOKINE RELEASE; ENDOTHELIUM CELL; GENE EXPRESSION; HEAT TREATMENT; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROMOTER REGION;

CELLS, CULTURED; CHLAMYDOPHILA PNEUMONIAE; CYTOKINES; ENDOTHELIAL CELLS; GENE EXPRESSION; HISTONES; HUMANS; RAC1 GTP-BINDING PROTEIN; SIMVASTATIN;

EID: 42549129871     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.107.161307     Document Type: Article

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