Interaction of pathogens with the endothelium

Thrombosis and Haemostasis

Volumn 89, Issue 1, 2003, Pages 18-24

  Hippenstiel, Stefan ^a   Suttorp, Norbert ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Bacteria; Endothelium; Infection; Inflammation; Virus

Indexed keywords

ADRENOMEDULLIN; CELL ADHESION MOLECULE; CHEMOKINE; CYTOKINE; EXOTOXIN; HEPARAN SULFATE; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; NITRIC OXIDE; PROTEINASE; RECEPTOR; THROMBOCYTE ACTIVATING FACTOR; THROMBOMODULIN; THROMBOPLASTIN;

BACTERIAL INFECTION; BACTERIUM; BACTERIUM ADHERENCE; BARTONELLA; BLOOD CLOTTING; BLOOD VESSEL PERMEABILITY; BLOOD VESSEL WALL; CELL ACTIVATION; CELL INTERACTION; ENDOTHELIUM CELL; ENDOTHELIUM LESION; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; IMMUNITY; INFLAMMATION; LEUKOCYTE; MEDIATOR RELEASE; MICROBIAL GROWTH; NONHUMAN; PARASITISM; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REVIEW; RICKETTSIA; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; VIRUS; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS REPLICATION;

EID: 0037247739     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1613538     Document Type: Review

References (51)

1. Valbuena G, Feng HM, Walker DH. Mechanisms of immunity against rickettsiae. New perspectives and opportunities offered by unusual intracellular parasites. Microbes Infect 2002; 4: 625-33.
2. Dehio C. Bartonella interactions with endothelial cells and erythrocytes. Trends Microbiol 2001; 9: 279-85.
3. 1. Cell Microbiol 1999; 1: 101-17.
4. Sinha B, Francois P, Que YA, Hussain M, Heilmann C, Moreillon P, Lew D, Krause KH, Peters G, Herrmann M. Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells. Infect Immun 2000; 68: 6871-8.
5. Massey RC, Kantzanou MN, Fowler T, Day NP, Schofield K, Wann ER, Berendt AR, Hook M, Peacock SJ. Fibronectin-binding protein A of Staphylococcus aureus has multiple, substituting, binding regions that mediate adherence to fibronectin and invasion of endothelial cells. Cell Microbiol 2001; 3: 839-51.
6. Flock JI. Extracellular-matrix-binding proteins as targets for the prevention of Staphylococcus aureus infections. Mol Med Today 1999; 5: 532-37.
7. Chavakis T, Hussain M, Kanse SM, Peters G, Bretzel RG, Flock JI, Herrmann M, Preissner KT. Staphylococcus aureus extracellular adherence protein serves as anti-inflammatory factor by inhibiting the recruitment of host leukocytes. Nat Med 2002; 8: 687-93.
8. Krüll M, Klucken AC, Wuppermann FN, Fuhrmann O, Magerl C, Seybold J, Hippenstiel S, Hegemann JH, Jantos CA, Suttorp N. Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae. J Immunol 1999; 162: 4834-41.
9. Fuhrmann O, Arvand M, Gohler A, Schmid M, Krüll M, Hippenstiel S, Seybold J, Dehio C, Suttorp N. Bartonella henselae induces NF-kappaB-dependent upregulation of adhesion molecules in cultured human endothelial cells: Possible role of outer membrane proteins as pathogenic factors. Infect Immun 2001; 69: 5088-97.
10. Bhakdi S, Grimminger F, Suttorp N, Walmrath D, Seeger W. Proteinaceous bacterial toxins and pathogenesis of sepsis syndrome and septic shock: The unknown connection . Med Microbiol Immunol 1994; 183: 119-44.
11. Karch H. The role of virulence factors in enterohemorrhagic Escherichia coli (EHEC)-associated hemolytic-uremic syndrome. Semin Thromb Hemost 2001; 27: 207-13.
12. Zysk G, Schneider-Wald BK, Hwang JH, Bejo L, Kim KS, Mitchell TJ, Hakenbeck R, Heinz HP. Pneumolysin is the main inducer of cytotoxicity to brain microvascular endothelial cells caused by Streptococcus pneumoniae. Infect Immun 2001; 69: 845-52.
13. Suttorp N, Hessz T, Seeger W, Wilke A, Koob R, Lutz F, Drenckhahn D. Bacterial exotoxins and endothelial permeability for water and albumin in vitro. Am J Physiol 1988; 255: C368-76.
14. Seeger W, Walter H, Neuhof H, Suttorp N, Bhakdi S. Escherichia coli hemolysin causes thromboxane-mediated hypertension and vascular leakage in rabbit lungs. Prog Clin Biol Res 1989; 308: 67-72.
15. Mayer K, Temmesfeld-Wollbrück B, Friedland A, Olschewski H, Reich M, Seeger W, Grimminger AF. Sever microcirculatory abnormalities elicited by E. coli hemolysin in the rabbit ileum mucosa. Am J Respir Crit Care Med 1999; 160: 1171-8.
16. Krüll M, Dold C, Hippenstiel S, Rosseau S, Lohmeyer J, Suttorp N. Escherichia coli hemolysin and Staphylococcus aureus alpha-toxin potently induce neutrophil adhesion to cultured human endothelial cells. J Immunol 1996; 157: 4133-40.
17. Cornelis GR. The Yersinia Yac-Yop 'Type III' weaponry. Nat Rev Mol Cell Biol 2002; 3: 742-54.
18. Andor A, Trulzsch K, Essler M, Roggenkamp A, Wiedemann A, Heesemann J, Aepfelbacher M. YopE of Yersinia, a GAP for Rho GTPases, selectively modulates Rac-dependent actin structures in endothelial cells. Cell Microbiol 2001; 3: 301-310.
19. Molestina RE, Klein JB, Miller RD, Pierce WH, Ramirez JA, Summersgill JT. Proteomic analysis of differentially expressed Chlamydia pneumoniae genes during persistent infection of HEp-2 cells. Infect Immun 2002; 70: 2976-81.
20. Underhill DM, Ozinsky A. Toll-like receptors: Key mediators of microbe detection. Curr Opin Immunol 2002; 14: 103-10.
21. Edfeldt K, Swedenborg J, Hansson GK, Yan ZQ. Expression of toll-like receptors in human atherosclerotic lesions: A possible pathway for plaque activation. Circulation 2002; 105: 1158-1161.
22. Triantafilou M, Triantafilou K. Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Trends Immunol 2002; 23: 301-4.
23. Bussolino F, Mitola S, Serini G, Barillari G, Ensoli B. Interactions between endothelial cells and HIV-1. Int J Biochem Cell Biol 2001; 33: 371-90.
24. Summersgill JT, Molestina RE, Miller RD, Ramirez JA. Interactions of Chlamydia pneumoniae with human endothelial cells. J Infect Dis 2000; 181: S479-82.
25. Cundell DR, Gerard NP, Gerard C, Idanpaan-Heikkila I, Tuomanen EI. Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activing factor. Nature 1995; 377: 435-8.
26. Nassif X, Bourdoulous S, Eugene E, Couraud PO. How do extracellular pathogens cross the blood-brain barrier? Trends Microbiol 2002; 10: 227-32.
27. Schnittler HJ, Feldmann H. Molecular pathogenesis of filovirus infections: Role of macrophages and endothelial cells. Curr Top Microbiol Immunol 1999; 235: 175-204.
28. Poole LJ, Yu Y, Kim PS, Zheng QZ, Pevsner J, Hayward GS. Altered patterns of cellular gene expression in dermal microvascular endothelial cells infected with Kaposi's sarcoma-associated herpesvirus. J Virol 2002; 76: 3395-420.
29. Steele-Mortimer O, Knodler LA, Finlay BB. Poisons, ruffles and rockets: Bacterial pathogens and the host cell cytoskeleton. Traffic 2000; 1: 107-18.
30. Drevets DA. Listeria monocytogenes virulence factors that stimulate endothelial cells. Infect Immun 1998; 66: 232-238.
31. Wolf K, Hackstadt T. Sphingomyelin trafficking in Chlamydia pneumoniae-infected cells. Cell Microbiol 2001; 3: 145-52.
32. Peters CJ, Zaki SR. Role of the endothelium in viral hemorrhagic fevers. Crit Care Med 2002; 30: S268-73.
33. De Martin R, Hoeth M, Hofer-Warbinek R, Schmid JA. The transcription factor NF-kappa B and the regulation of vascular cell function. Arterioscler Thromb Vasc Biol 2000; 20: E83-8.
34. Hack CE, Zeerleder S. The endothelium in sepsis: Source of and a target for inflammation. Crit Care Med 2001; 29: S21-S7.
35. Granger DN, Kubes P. The microcirculation and inflammation: Modulation of leukocyte-endothelial cell adhesion. J Leukoc Biol 1994; 55: 662-75.
36. Vanhoutte PM, Mombouli JV. Vascular endothelium: Vasoactive mediators. Prog Cardiovasc Dis 1996; 39: 229-38.
37. Suttorp N, Fuhrmann M, Tannert-Otto S, Grimminger F, Bhadki S. Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells. J Exp Med 1993; 178: 337-41.
38. Wang P. Adrenomedullin in sepsis and septic shock. Shock 1998; 10: 383-4.
39. Shindo T, Kurihara H, Maemura K, Kurihara Y, Kuwaki T, Izumida T, Minamino N, Ju JK, Morita H, Ohhashi Y, Kumada M, Kangawa K, Nagai R, Yazaki Y. Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature. Circulation 2000; 101: 2309-16.
40. Hippenstiel S, Witzenrath M, Schmeck B, Hocke A, Krisp M, Krüll M, Seybold J, Seeger W, Rascher W, Schütte H, Suttorp N. Adrenomedullin reduces endothelial hyperpermeability. Circ Res 2002; 91: 618-25.
41. McEver RP. Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation. Thromb Haemost 2001; 86: 746-56.
42. Coughlin SR. Protease-activated receptors in vascular biology. Thromb Haemost 2001; 86; 298-307.
43. Patti JM, Allen BL, McGavin MJ, Höök M. MSCRAMM-mediated adherence of micro-organisms to host tissues. Annu Rev Microbiol 1994; 48: 585-617.
44. O'Brien L, Kerrigan SW, Kaw G, Hogan M, Penades J, Litt D, Fitzgerald DJ, Foster TJ, Cox D. Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: Roles for the clumping factors ClfA and ClfB, the serine-aspartate repeat protein SdrE and protein A. Mol Microbiol 2002; 44: 1033-44.
45. Sullam PM, Bayer AS, Foss WM, Cheung AL. Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis. Infect Immun 1996; 64: 4915-21.
46. Lahteenmaki K, Kuusela P, Korhonen TK. Bacterial plasminogen activators and receptors. FEMS Microbiol Rev 2001; 25: 531-52.
47. Stevens T, Garcia JG, Shasby DM, Bhattacharya J, Malik AB. Mechanisms regulating endothelial cell barrier function. Am J Physiol Lung Cell Mol Physiol 2000; 279: L419-22.
48. Ljungh A, Wadstrom T. Interactions of bacterial adhesins with the extracellular matrix. Adv Exp Med Biol 1996; 408: 129-40.
49. Noll G. Pathogenesis of atherosclerosis: A possible relation to infection. Atherosclerosis 1998; 140: S3-9.
50. Isberg RR, Barnes P. Dancing with the host; Flow-dependent bacterial adhesion. Cell 2002; 110: 1-4.
51. Huang SH, Triche T, Jong AY. Infectomics: Genomics and proteomics of microbial infections. Funct Integr Genomics 2002; 1: 331-44.