메뉴 건너뛰기




Volumn 63, Issue 5, 2008, Pages 513-519

Bioengineering approaches to controlled protein delivery

Author keywords

[No Author keywords available]

Indexed keywords

DRUG VEHICLE; GROWTH FACTOR; MACROGOL; NANOPARTICLE; POLYGLACTIN; POLYLACTIC ACID; POLYMER;

EID: 42449159405     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/PDR.0b013e318165f14d     Document Type: Review
Times cited : (55)

References (76)
  • 2
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: Entering the mainstream
    • Allen TM, Cullis PR 2004 Drug delivery systems: entering the mainstream. Science 303:1818-1822
    • (2004) Science , vol.303 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 3
    • 35048842305 scopus 로고    scopus 로고
    • Liposomal drug delivery systems: An update review
    • Samad A, Sultana Y, Aqil M 2007 Liposomal drug delivery systems: an update review. Curr Drug Deliv 4:297-305
    • (2007) Curr Drug Deliv , vol.4 , pp. 297-305
    • Samad, A.1    Sultana, Y.2    Aqil, M.3
  • 4
    • 0038445582 scopus 로고    scopus 로고
    • Biodegradable microspheres for protein delivery
    • Sinha VR, Trehan A 2003 Biodegradable microspheres for protein delivery. J Control Release 90:261-280
    • (2003) J Control Release , vol.90 , pp. 261-280
    • Sinha, V.R.1    Trehan, A.2
  • 7
    • 0037027390 scopus 로고    scopus 로고
    • Implantable, polymeric systems for modulated drug delivery
    • Sershen S, West J 2002 Implantable, polymeric systems for modulated drug delivery. Adv Drug Deliv Rev 54:1225-1235
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1225-1235
    • Sershen, S.1    West, J.2
  • 8
    • 34250805948 scopus 로고    scopus 로고
    • Polymeric protein delivery systems
    • Lee KY, Yuk SH 2007 Polymeric protein delivery systems. Prog Polym Sci 32:669-697
    • (2007) Prog Polym Sci , vol.32 , pp. 669-697
    • Lee, K.Y.1    Yuk, S.H.2
  • 9
    • 0036490227 scopus 로고    scopus 로고
    • Building drug delivery into tissue engineering design
    • Saltzman WM, Olbricht WL 2002 Building drug delivery into tissue engineering design. Nat Rev Drug Discov 1:177-186
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 177-186
    • Saltzman, W.M.1    Olbricht, W.L.2
  • 10
    • 0029804038 scopus 로고    scopus 로고
    • Stabilization of nerve growth factor in controlled release polymers and in tissue
    • Krewson CE, Dause R, Mak M, Saltzman WM 1996 Stabilization of nerve growth factor in controlled release polymers and in tissue. J Biomater Sci Polym Ed 8:103-117
    • (1996) J Biomater Sci Polym Ed , vol.8 , pp. 103-117
    • Krewson, C.E.1    Dause, R.2    Mak, M.3    Saltzman, W.M.4
  • 12
    • 0032479801 scopus 로고    scopus 로고
    • Materials for protein delivery in tissue engineering
    • Baldwin SP, Mark Saltzman W 1998 Materials for protein delivery in tissue engineering. Adv Drug Deliv Rev 33:71-86
    • (1998) Adv Drug Deliv Rev , vol.33 , pp. 71-86
    • Baldwin, S.P.1    Mark Saltzman, W.2
  • 13
    • 34249951300 scopus 로고    scopus 로고
    • Matrices and scaffolds for protein delivery in tissue engineering
    • Tessmar JK, Gopferich AM 2007 Matrices and scaffolds for protein delivery in tissue engineering. Adv Drug Deliv Rev 59:274-291
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 274-291
    • Tessmar, J.K.1    Gopferich, A.M.2
  • 14
    • 23944489927 scopus 로고    scopus 로고
    • Precipitation casting of drug-loaded microporous PCL matrices: Incorporation of progesterone by codissolution
    • Chang HI, Williamson MR, Perrie Y, Coombes AG 2005 Precipitation casting of drug-loaded microporous PCL matrices: incorporation of progesterone by codissolution. J Control Release 106:263-272
    • (2005) J Control Release , vol.106 , pp. 263-272
    • Chang, H.I.1    Williamson, M.R.2    Perrie, Y.3    Coombes, A.G.4
  • 15
    • 33846706548 scopus 로고    scopus 로고
    • Customized PEG-derived copolymers for tissue-engineering applications
    • Tessmar JK, Gopferich AM 2007 Customized PEG-derived copolymers for tissue-engineering applications. Macromol Biosci 7:23-39
    • (2007) Macromol Biosci , vol.7 , pp. 23-39
    • Tessmar, J.K.1    Gopferich, A.M.2
  • 17
    • 85038373961 scopus 로고    scopus 로고
    • Salt leaching for polymer scaffolds: Laboratory-scale manufacture of cell carriers
    • Ma PX, Elisseeff JH (eds, Taylor & Francis CRC Press, Boca Raton, pp
    • Tessmar JK, Holland TA, Mikos AG 2005 Salt leaching for polymer scaffolds: laboratory-scale manufacture of cell carriers. In: Ma PX, Elisseeff JH (eds) Scaffolding in Tissue Engineering. Taylor & Francis (CRC Press), Boca Raton, pp 111-124
    • (2005) Scaffolding in Tissue Engineering , pp. 111-124
    • Tessmar, J.K.1    Holland, T.A.2    Mikos, A.G.3
  • 19
    • 0034672868 scopus 로고    scopus 로고
    • A biodegradable polymer scaffold for delivery of osteotropic factors
    • Whang K, Goldstick TK, Healy KE 2000 A biodegradable polymer scaffold for delivery of osteotropic factors. Biomaterials 21:2545-2551
    • (2000) Biomaterials , vol.21 , pp. 2545-2551
    • Whang, K.1    Goldstick, T.K.2    Healy, K.E.3
  • 20
  • 21
    • 32644479707 scopus 로고    scopus 로고
    • Electrospun silk-BMP-2 scaffolds for bone tissue engineering
    • Li C, Vepari C, Jin H-J, Kim HJ, Kaplan DL 2006 Electrospun silk-BMP-2 scaffolds for bone tissue engineering. Biomaterials 27:3115-3124
    • (2006) Biomaterials , vol.27 , pp. 3115-3124
    • Li, C.1    Vepari, C.2    Jin, H.-J.3    Kim, H.J.4    Kaplan, D.L.5
  • 22
    • 33646354615 scopus 로고    scopus 로고
    • Coaxial electro-spinning of (fluorescein isothiocyanate-conjugated bovine serum albumin)-encapsulated poly(-caprolactone) nanofibers for sustained release
    • Zhang YZ, Wang X, Feng Y, Li J, Lim CT, Ramakrishna S 2006 Coaxial electro-spinning of (fluorescein isothiocyanate-conjugated bovine serum albumin)-encapsulated poly(-caprolactone) nanofibers for sustained release. Biomacromolecules 7:1049-1057
    • (2006) Biomacromolecules , vol.7 , pp. 1049-1057
    • Zhang, Y.Z.1    Wang, X.2    Feng, Y.3    Li, J.4    Lim, C.T.5    Ramakrishna, S.6
  • 23
    • 0037458934 scopus 로고    scopus 로고
    • A novel method to obtain protein release from porous polymer scaffolds: Emulsion coating
    • Sohier J, Haan RE, de Groot K, Bezemer JM 2003 A novel method to obtain protein release from porous polymer scaffolds: emulsion coating. J Control Release 87:57-68
    • (2003) J Control Release , vol.87 , pp. 57-68
    • Sohier, J.1    Haan, R.E.2    de Groot, K.3    Bezemer, J.M.4
  • 24
    • 0037028063 scopus 로고    scopus 로고
    • Controlled release of an osteogenic peptide from injectable biodegradable polymeric composites
    • Hedberg EL, Tang A, Crowther RS, Carney DH, Mikos AG 2002 Controlled release of an osteogenic peptide from injectable biodegradable polymeric composites. J Control Release 84:137-150
    • (2002) J Control Release , vol.84 , pp. 137-150
    • Hedberg, E.L.1    Tang, A.2    Crowther, R.S.3    Carney, D.H.4    Mikos, A.G.5
  • 25
    • 23744517121 scopus 로고    scopus 로고
    • Controlled release of rhBMP-2 loaded poly(D,L-lactic-co-glycolic acid)/calcium phosphate cement composites in vivo
    • Ruhe PQ, Boerman OC, Russel FG, Spauwen PH, Mikos AG, Jansen JA 2005 Controlled release of rhBMP-2 loaded poly(D,L-lactic-co-glycolic acid)/calcium phosphate cement composites in vivo. J Control Release 106:162-171
    • (2005) J Control Release , vol.106 , pp. 162-171
    • Ruhe, P.Q.1    Boerman, O.C.2    Russel, F.G.3    Spauwen, P.H.4    Mikos, A.G.5    Jansen, J.A.6
  • 26
    • 0036239974 scopus 로고    scopus 로고
    • Surface studies of coated polymer microspheres and protein release from tissue-engineered scaffolds
    • Meese TM, Hu Y, Nowak RW, Marra KG 2002 Surface studies of coated polymer microspheres and protein release from tissue-engineered scaffolds. J Biomater Sci Polym Ed 13:141-151
    • (2002) J Biomater Sci Polym Ed , vol.13 , pp. 141-151
    • Meese, T.M.1    Hu, Y.2    Nowak, R.W.3    Marra, K.G.4
  • 27
    • 34547202478 scopus 로고    scopus 로고
    • Coupling of biotin-(poly(ethylene glycol))amine to poly(D,L- lactide-co-glycolide) nanoparticles for versatile surface modification
    • Weiss B, Schneider M, Muys L, Taetz S, Neumann D, Schaefer UF, Lehr CM 2007 Coupling of biotin-(poly(ethylene glycol))amine to poly(D,L- lactide-co-glycolide) nanoparticles for versatile surface modification. Bioconjug Chem 18:1087-1094
    • (2007) Bioconjug Chem , vol.18 , pp. 1087-1094
    • Weiss, B.1    Schneider, M.2    Muys, L.3    Taetz, S.4    Neumann, D.5    Schaefer, U.F.6    Lehr, C.M.7
  • 28
    • 0028130107 scopus 로고
    • Polymer substrates for controlled biological interactions
    • Cima LG 1994 Polymer substrates for controlled biological interactions. J Cell Biochem 56:155-161
    • (1994) J Cell Biochem , vol.56 , pp. 155-161
    • Cima, L.G.1
  • 29
    • 0030270003 scopus 로고    scopus 로고
    • Use of p-nitrophenyl chloroformate chemistry to immobilize protein on orthopedic biomaterials
    • Mikulec LJ, Puleo DA 1996 Use of p-nitrophenyl chloroformate chemistry to immobilize protein on orthopedic biomaterials. J Biomed Mater Res 32:203-208
    • (1996) J Biomed Mater Res , vol.32 , pp. 203-208
    • Mikulec, L.J.1    Puleo, D.A.2
  • 30
    • 0031862030 scopus 로고    scopus 로고
    • Creating biomimetic microenvironments with synthetic polymer-peptide hybrid molecules
    • Shakesheff K, Cannizzaro S, Langer R 1998 Creating biomimetic microenvironments with synthetic polymer-peptide hybrid molecules. J Biomater Sci Polym Ed 9:507-518
    • (1998) J Biomater Sci Polym Ed , vol.9 , pp. 507-518
    • Shakesheff, K.1    Cannizzaro, S.2    Langer, R.3
  • 31
    • 0035135284 scopus 로고    scopus 로고
    • Surfactant-immobilized fibronectin enhances bioactivity and regulates sensory neurite outgrowth
    • Biran R, Webb K, Noble MD, Tresco PA 2001 Surfactant-immobilized fibronectin enhances bioactivity and regulates sensory neurite outgrowth. J Biomed Mater Res 55:1-12
    • (2001) J Biomed Mater Res , vol.55 , pp. 1-12
    • Biran, R.1    Webb, K.2    Noble, M.D.3    Tresco, P.A.4
  • 33
    • 0029791838 scopus 로고    scopus 로고
    • Tethered epidermal growth factor as a paradigm for growth factor-induced stimulation from the solid phase
    • Kuhl PR, Griffith-Cima LG 1996 Tethered epidermal growth factor as a paradigm for growth factor-induced stimulation from the solid phase. Nat Med 2:1022-1027
    • (1996) Nat Med , vol.2 , pp. 1022-1027
    • Kuhl, P.R.1    Griffith-Cima, L.G.2
  • 34
    • 0031745495 scopus 로고    scopus 로고
    • Preparation of insulin-immobilized polyurethanes and their interaction with human fibroblasts
    • Kim EJ, Kang IK, Jang MK, Park YB 1998 Preparation of insulin-immobilized polyurethanes and their interaction with human fibroblasts. Biomaterials 19:239-249
    • (1998) Biomaterials , vol.19 , pp. 239-249
    • Kim, E.J.1    Kang, I.K.2    Jang, M.K.3    Park, Y.B.4
  • 35
    • 0010239438 scopus 로고
    • Interaction of nerve growth factor with surface membranes: Biological competence of insolubilized nerve growth factor
    • Frazier WA, Boyd LF, Bradshaw RA 1973 Interaction of nerve growth factor with surface membranes: biological competence of insolubilized nerve growth factor. Proc Natl Acad Sci USA 70:2931-2935
    • (1973) Proc Natl Acad Sci USA , vol.70 , pp. 2931-2935
    • Frazier, W.A.1    Boyd, L.F.2    Bradshaw, R.A.3
  • 36
    • 0036263390 scopus 로고    scopus 로고
    • Hydrogel-based colloidal polymeric system for protein and drug delivery: Physical and chemical characterization, permeability control and applications
    • Arora M ed, Springer Berlin, Heidelberg, pp
    • Prokop A, Kozlov E, Carlesso G, Davidson J 2002 Hydrogel-based colloidal polymeric system for protein and drug delivery: physical and chemical characterization, permeability control and applications. In: Arora M (ed) Filled Elastomers Drug Delivery Systems. Springer Berlin, Heidelberg, pp 119-173
    • (2002) Filled Elastomers Drug Delivery Systems , pp. 119-173
    • Prokop, A.1    Kozlov, E.2    Carlesso, G.3    Davidson, J.4
  • 37
    • 0035385135 scopus 로고    scopus 로고
    • Hydrogels for tissue engineering
    • Lee KY, Mooney DJ 2001 Hydrogels for tissue engineering. Chem Rev 101:1869-1879
    • (2001) Chem Rev , vol.101 , pp. 1869-1879
    • Lee, K.Y.1    Mooney, D.J.2
  • 38
    • 0031761745 scopus 로고    scopus 로고
    • Release from alginate enhances the biological activity of vascular endothelial growth factor
    • Peters MC, Isenberg BC, Rowley JA, Mooney DJ 1998 Release from alginate enhances the biological activity of vascular endothelial growth factor. J Biomater Sci Polym Ed 9:1267-1278
    • (1998) J Biomater Sci Polym Ed , vol.9 , pp. 1267-1278
    • Peters, M.C.1    Isenberg, B.C.2    Rowley, J.A.3    Mooney, D.J.4
  • 39
    • 33847307132 scopus 로고    scopus 로고
    • Controlled-release of epidermal growth factor from cationized gelatin hydrogel enhances corneal epithelial wound healing
    • Hori K, Sotozono C, Hamuro J, Yamasaki K, Kimura Y, Ozeki M, Tabata Y, Kinoshita S 2007 Controlled-release of epidermal growth factor from cationized gelatin hydrogel enhances corneal epithelial wound healing. J Control Release 118:169-176
    • (2007) J Control Release , vol.118 , pp. 169-176
    • Hori, K.1    Sotozono, C.2    Hamuro, J.3    Yamasaki, K.4    Kimura, Y.5    Ozeki, M.6    Tabata, Y.7    Kinoshita, S.8
  • 40
    • 15244349102 scopus 로고    scopus 로고
    • Sustained release of human growth hormone from in situ forming hydrogels using self-assembly of fluoroalkyl-ended poly(ethylene glycol)
    • Tae G, Kornfield JA, Hubbell JA 2005 Sustained release of human growth hormone from in situ forming hydrogels using self-assembly of fluoroalkyl-ended poly(ethylene glycol). Biomaterials 26:5259-5266
    • (2005) Biomaterials , vol.26 , pp. 5259-5266
    • Tae, G.1    Kornfield, J.A.2    Hubbell, J.A.3
  • 41
    • 26844530250 scopus 로고    scopus 로고
    • Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels
    • Burdick JA, Ward M, Liang E, Young MJ, Langer R 2006 Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels. Biomaterials 27:452-459
    • (2006) Biomaterials , vol.27 , pp. 452-459
    • Burdick, J.A.1    Ward, M.2    Liang, E.3    Young, M.J.4    Langer, R.5
  • 42
    • 7944225916 scopus 로고    scopus 로고
    • Mechanically engineered hydrogel scaffolds for axonal growth and angiogenesis after transplantation in spinal cord injury
    • Bakshi A, Fisher O, Dagci T, Himes BT, Fischer I, Lowman A 2004 Mechanically engineered hydrogel scaffolds for axonal growth and angiogenesis after transplantation in spinal cord injury. J Neurosurg Spine 1:322-329
    • (2004) J Neurosurg Spine , vol.1 , pp. 322-329
    • Bakshi, A.1    Fisher, O.2    Dagci, T.3    Himes, B.T.4    Fischer, I.5    Lowman, A.6
  • 43
    • 33748430801 scopus 로고    scopus 로고
    • An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury
    • Piantino J, Burdick JA, Goldberg D, Langer R, Benowitz LI 2006 An injectable, biodegradable hydrogel for trophic factor delivery enhances axonal rewiring and improves performance after spinal cord injury. Exp Neurol 201:359-367
    • (2006) Exp Neurol , vol.201 , pp. 359-367
    • Piantino, J.1    Burdick, J.A.2    Goldberg, D.3    Langer, R.4    Benowitz, L.I.5
  • 44
    • 34247561381 scopus 로고    scopus 로고
    • Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering
    • Park H, Temenoff JS, Tabata Y, Caplan AI, Mikos AG 2007 Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials 28:3217-3227
    • (2007) Biomaterials , vol.28 , pp. 3217-3227
    • Park, H.1    Temenoff, J.S.2    Tabata, Y.3    Caplan, A.I.4    Mikos, A.G.5
  • 45
    • 28444460463 scopus 로고    scopus 로고
    • Controlled release of bioactive TGF-[beta]1 from microspheres embedded within biodegradable hydrogels
    • DeFail AJ, Chu CR, Izzo N, Marra KG 2006 Controlled release of bioactive TGF-[beta]1 from microspheres embedded within biodegradable hydrogels. Biomaterials 27:1579-1585
    • (2006) Biomaterials , vol.27 , pp. 1579-1585
    • DeFail, A.J.1    Chu, C.R.2    Izzo, N.3    Marra, K.G.4
  • 46
    • 21244483142 scopus 로고    scopus 로고
    • Insulin-like growth factor I-releasing alginate-tricalciumphosphate composites for bone regeneration
    • Luginbuehl V, Wenk E, Koch A, Gander B, Merkle HP, Meinel L 2005 Insulin-like growth factor I-releasing alginate-tricalciumphosphate composites for bone regeneration. Pharm Res 22:940-950
    • (2005) Pharm Res , vol.22 , pp. 940-950
    • Luginbuehl, V.1    Wenk, E.2    Koch, A.3    Gander, B.4    Merkle, H.P.5    Meinel, L.6
  • 47
    • 0035284541 scopus 로고    scopus 로고
    • Tethered-TGF-[beta] increases extracellular matrix production of vascular smooth muscle cells
    • Mann BK, Schmedlen RH, West JL 2001 Tethered-TGF-[beta] increases extracellular matrix production of vascular smooth muscle cells. Biomaterials 22:439-444
    • (2001) Biomaterials , vol.22 , pp. 439-444
    • Mann, B.K.1    Schmedlen, R.H.2    West, J.L.3
  • 48
    • 0037462997 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug and gene delivery to cells and tissue
    • Panyam J, Labhasetwar V 2003 Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev 55:329-347
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 329-347
    • Panyam, J.1    Labhasetwar, V.2
  • 49
    • 0031720748 scopus 로고    scopus 로고
    • Improving drug delivery to intracerebral tumor and surrounding brain in a rodent model: A comparison of osmotic versus bradykinin modification of the blood-brain and/or blood-tumor barriers
    • Kroll RA, Pagel MA, Muldoon LL, Roman-Goldstein S, Fiamengo SA, Neuwelt EA 1998 Improving drug delivery to intracerebral tumor and surrounding brain in a rodent model: a comparison of osmotic versus bradykinin modification of the blood-brain and/or blood-tumor barriers. Neurosurgery 43:879-886
    • (1998) Neurosurgery , vol.43 , pp. 879-886
    • Kroll, R.A.1    Pagel, M.A.2    Muldoon, L.L.3    Roman-Goldstein, S.4    Fiamengo, S.A.5    Neuwelt, E.A.6
  • 50
    • 0031469673 scopus 로고    scopus 로고
    • The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent
    • Desai MP, Labhasetwar V, Walter E, Levy RJ, Amidon GL 1997 The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent. Pharm Res 14:1568-1573
    • (1997) Pharm Res , vol.14 , pp. 1568-1573
    • Desai, M.P.1    Labhasetwar, V.2    Walter, E.3    Levy, R.J.4    Amidon, G.L.5
  • 51
    • 0025053154 scopus 로고
    • Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: Problems associated with preparative techniques and release properties
    • Jalil R, Nixon JR 1990 Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: problems associated with preparative techniques and release properties. J Microencapsul 7:297-325
    • (1990) J Microencapsul , vol.7 , pp. 297-325
    • Jalil, R.1    Nixon, J.R.2
  • 52
    • 4444246813 scopus 로고    scopus 로고
    • Polymer microspheres for controlled drug release
    • Freiberg S, Zhu XX 2004 Polymer microspheres for controlled drug release. Int J Pharm 282:1-18
    • (2004) Int J Pharm , vol.282 , pp. 1-18
    • Freiberg, S.1    Zhu, X.X.2
  • 53
    • 0035192562 scopus 로고    scopus 로고
    • Biodegradable microspheres containing group B Streptococcus vaccine: Immune response in mice
    • Hunter SK, Andracki ME, Krieg AM 2001 Biodegradable microspheres containing group B Streptococcus vaccine: immune response in mice. Am J Obstet Gynecol 185:1174-1179
    • (2001) Am J Obstet Gynecol , vol.185 , pp. 1174-1179
    • Hunter, S.K.1    Andracki, M.E.2    Krieg, A.M.3
  • 54
    • 0034105785 scopus 로고    scopus 로고
    • Immune response with biodegradable nanospheres and alum: Studies in rabbits using staphylococcal enterotoxin B-toxoid
    • Desai MP, Hilfinger JM, Amidon GL, Levy RJ, Labhasetwar V 2000 Immune response with biodegradable nanospheres and alum: studies in rabbits using staphylococcal enterotoxin B-toxoid. J Microencapsul 17:215-225
    • (2000) J Microencapsul , vol.17 , pp. 215-225
    • Desai, M.P.1    Hilfinger, J.M.2    Amidon, G.L.3    Levy, R.J.4    Labhasetwar, V.5
  • 55
    • 0037006608 scopus 로고    scopus 로고
    • Tetanus toxoid microspheres consisting of biodegradable poly(lactide-co-glycolide)- and ABA-triblockcopolymers: Immune response in mice
    • Jung T, Koneberg R, Hungerer KD, Kissel T 2002 Tetanus toxoid microspheres consisting of biodegradable poly(lactide-co-glycolide)- and ABA-triblockcopolymers: immune response in mice. Int J Pharm 234:75-90
    • (2002) Int J Pharm , vol.234 , pp. 75-90
    • Jung, T.1    Koneberg, R.2    Hungerer, K.D.3    Kissel, T.4
  • 56
    • 0032825349 scopus 로고    scopus 로고
    • Immunogenicity of single-dose diphtheria vaccines based on PLA/PLGA microspheres in guinea pigs
    • Johansen P, Moon L, Tamber H, Merkle HP, Gander B, Sesardic D 1999 Immunogenicity of single-dose diphtheria vaccines based on PLA/PLGA microspheres in guinea pigs. Vaccine 18:209-215
    • (1999) Vaccine , vol.18 , pp. 209-215
    • Johansen, P.1    Moon, L.2    Tamber, H.3    Merkle, H.P.4    Gander, B.5    Sesardic, D.6
  • 57
    • 9344239901 scopus 로고    scopus 로고
    • Gelatin hydrogel microspheres enable pinpoint delivery of basic fibroblast growth factor for the development of functional collateral vessels
    • Hosaka A, Koyama H, Kushibiki T, Tabata Y, Nishiyama N, Miyata T, Shigematsu H, Takato T, Nagawa H 2004 Gelatin hydrogel microspheres enable pinpoint delivery of basic fibroblast growth factor for the development of functional collateral vessels. Circulation 110:3322-3328
    • (2004) Circulation , vol.110 , pp. 3322-3328
    • Hosaka, A.1    Koyama, H.2    Kushibiki, T.3    Tabata, Y.4    Nishiyama, N.5    Miyata, T.6    Shigematsu, H.7    Takato, T.8    Nagawa, H.9
  • 58
    • 0035858370 scopus 로고    scopus 로고
    • Development of poly-(D,L-lactide -co-glycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis
    • Cleland JL, Duenas ET, Park A, Daugherty A, Kahn J, Kowalski J, Cuthbertson A 2001 Development of poly-(D,L-lactide -co-glycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis. J Control Release 72:13-24
    • (2001) J Control Release , vol.72 , pp. 13-24
    • Cleland, J.L.1    Duenas, E.T.2    Park, A.3    Daugherty, A.4    Kahn, J.5    Kowalski, J.6    Cuthbertson, A.7
  • 59
    • 0034073109 scopus 로고    scopus 로고
    • De novo adipose tissue generation through long-term, local delivery of insulin and insulin-like growth factor-1 by PLGA/PEG microspheres in an in vivo rat model: A novel concept and capability
    • Yuksel E, Weinfeld AB, Cleek R, Waugh JM, Jensen J, Boutros S, Shenaq SM, Spira M 2000 De novo adipose tissue generation through long-term, local delivery of insulin and insulin-like growth factor-1 by PLGA/PEG microspheres in an in vivo rat model: a novel concept and capability. Plast Reconstr Surg 105:1721-1729
    • (2000) Plast Reconstr Surg , vol.105 , pp. 1721-1729
    • Yuksel, E.1    Weinfeld, A.B.2    Cleek, R.3    Waugh, J.M.4    Jensen, J.5    Boutros, S.6    Shenaq, S.M.7    Spira, M.8
  • 60
    • 0035839179 scopus 로고    scopus 로고
    • Preparation and evaluation of poly(L-lactic acid) microspheres containing rhEGF for chronic gastric ulcer healing
    • Han K, Lee KD, Gao ZG, Park JS 2001 Preparation and evaluation of poly(L-lactic acid) microspheres containing rhEGF for chronic gastric ulcer healing. J Control Release 75:259-269
    • (2001) J Control Release , vol.75 , pp. 259-269
    • Han, K.1    Lee, K.D.2    Gao, Z.G.3    Park, J.S.4
  • 61
    • 0033118540 scopus 로고    scopus 로고
    • The role of recombinant human bone morphogenetic protein-2 in PLGA capsules at an extraskeletal site of the rat
    • Isobe M, Yamazaki Y, Mori M, Ishihara K, Nakabayashi N, Amagasa T 1999 The role of recombinant human bone morphogenetic protein-2 in PLGA capsules at an extraskeletal site of the rat. J Biomed Mater Res 45:36-41
    • (1999) J Biomed Mater Res , vol.45 , pp. 36-41
    • Isobe, M.1    Yamazaki, Y.2    Mori, M.3    Ishihara, K.4    Nakabayashi, N.5    Amagasa, T.6
  • 63
    • 33747874701 scopus 로고    scopus 로고
    • A PEDF N-terminal peptide protects the retina from ischemic injury when delivered in PLGA nanospheres
    • Li H, Tran VV, Hu Y, Mark Saltzman W, Barnstable CJ, Tombran-Tink J 2006 A PEDF N-terminal peptide protects the retina from ischemic injury when delivered in PLGA nanospheres. Exp Eye Res 83:824-833
    • (2006) Exp Eye Res , vol.83 , pp. 824-833
    • Li, H.1    Tran, V.V.2    Hu, Y.3    Mark Saltzman, W.4    Barnstable, C.J.5    Tombran-Tink, J.6
  • 65
    • 0032484233 scopus 로고    scopus 로고
    • Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: Protein stabilization and in-vitro release properties
    • Morlock M, Kissel T, Li YX, Koll H, Winter G 1998 Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: protein stabilization and in-vitro release properties. J Control Release 56:105-115
    • (1998) J Control Release , vol.56 , pp. 105-115
    • Morlock, M.1    Kissel, T.2    Li, Y.X.3    Koll, H.4    Winter, G.5
  • 67
    • 0036732080 scopus 로고    scopus 로고
    • Study on biodegradable microspheres containing recombinant interferon-alpha-2a
    • Zhou S, Deng X, He S, Li X, Jia W, Wei D, Zhang Z, Ma J 2002 Study on biodegradable microspheres containing recombinant interferon-alpha-2a. J Pharm Pharmacol 54:1287-1292
    • (2002) J Pharm Pharmacol , vol.54 , pp. 1287-1292
    • Zhou, S.1    Deng, X.2    He, S.3    Li, X.4    Jia, W.5    Wei, D.6    Zhang, Z.7    Ma, J.8
  • 68
    • 33644540762 scopus 로고    scopus 로고
    • Regulating activation of transplanted cells controls tissue regeneration
    • Hill E, Boontheekul T, Mooney DJ 2006 Regulating activation of transplanted cells controls tissue regeneration. Proc Natl Acad Sci USA 103:2494-2499
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2494-2499
    • Hill, E.1    Boontheekul, T.2    Mooney, D.J.3
  • 69
    • 34447253328 scopus 로고    scopus 로고
    • Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects
    • Oest ME, Dupont KM, Kong H-J, Mooney DJ, Guldberg RE 2007 Quantitative assessment of scaffold and growth factor-mediated repair of critically sized bone defects. J Orthop Res 25:941-950
    • (2007) J Orthop Res , vol.25 , pp. 941-950
    • Oest, M.E.1    Dupont, K.M.2    Kong, H.-J.3    Mooney, D.J.4    Guldberg, R.E.5
  • 71
    • 33746644192 scopus 로고    scopus 로고
    • Issues related to targeted delivery of proteins and peptides
    • Lu Y, Yang J, Sega E 2006 Issues related to targeted delivery of proteins and peptides. AAPS J 8:E466-E478
    • (2006) AAPS , vol.J 8
    • Lu, Y.1    Yang, J.2    Sega, E.3
  • 72
    • 33745107170 scopus 로고    scopus 로고
    • Strategies to improve plasma half life time of peptide and protein drugs
    • Werle M, Bernkop-Schnurch A 2006 Strategies to improve plasma half life time of peptide and protein drugs. Amino Acids 30:351-367
    • (2006) Amino Acids , vol.30 , pp. 351-367
    • Werle, M.1    Bernkop-Schnurch, A.2
  • 73
    • 3042796460 scopus 로고    scopus 로고
    • Multiphoton microscopy guides neurotrophin modification with poly(ethylene glycol) to enhance interstitial diffusion
    • Stroh M, Zipfel WR, Williams RM, Ma SC, Webb WW, Saltzman WM 2004 Multiphoton microscopy guides neurotrophin modification with poly(ethylene glycol) to enhance interstitial diffusion. Nat Mater 3:489-494
    • (2004) Nat Mater , vol.3 , pp. 489-494
    • Stroh, M.1    Zipfel, W.R.2    Williams, R.M.3    Ma, S.C.4    Webb, W.W.5    Saltzman, W.M.6
  • 74
    • 0037462992 scopus 로고    scopus 로고
    • PEGylated nanoparticles for biological and pharmaceutical applications
    • Otsuka H, Nagasaki Y, Kataoka K 2003 PEGylated nanoparticles for biological and pharmaceutical applications. Adv Drug Deliv Rev 55:403-419
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 403-419
    • Otsuka, H.1    Nagasaki, Y.2    Kataoka, K.3
  • 75
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
    • Maeda H, Wu J, Sawa T, Matsumura Y, Hori K 2000 Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 65:271-284
    • (2000) J Control Release , vol.65 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5
  • 76
    • 34250685362 scopus 로고    scopus 로고
    • Nanosystems for simultaneous imaging and drug delivery to T cells
    • Fahmy TM, Fong PM, Park J, Constable T, Saltzman WM 2007 Nanosystems for simultaneous imaging and drug delivery to T cells. AAPS J 9:E171-E180
    • (2007) AAPS , vol.J 9
    • Fahmy, T.M.1    Fong, P.M.2    Park, J.3    Constable, T.4    Saltzman, W.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.