Materials for protein delivery in tissue engineering

Advanced Drug Delivery Reviews

Volumn 33, Issue 1-2, 1998, Pages 71-86

  Baldwin, Samuel P ^a   Saltzman, W Mark ^a  

^a Cornell University   (United States)

Author keywords

Controlled release; Drug delivery; Growth factors; Polymers; Protein therapeutics; Tissue engineering

Indexed keywords

GROWTH KINETICS; PROTEINS; TISSUE CULTURE;

PROTEIN THERAPY; TISSUE ENGINEERING;

CONTROLLED DRUG DELIVERY;

GROWTH FACTOR; POLYMER;

BIOMEDICAL ENGINEERING; CELL MIGRATION; CELL PROLIFERATION; DRUG DELIVERY SYSTEM; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN TARGETING; PROTEIN TRANSPORT; REVIEW; TISSUE ENGINEERING;

EID: 0032479801     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(98)00021-0     Document Type: Review

References (99)

1. [1] L.A. Greene, A.S. Tischler, Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor, Proc. Natl. Acad. Sci. USA 73 (1976) 2424-2428.
2. [2] R. Ross, J. Glomset, B. Kariya, L. Harker, A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro, Proc. Natl. Acad. Sci. USA 71 (1974) 1207-1210.
3. [3] T.F. Deuel, Growth Factors, in: R. Lanza, R. Langer, W. Chick (Eds.), Principles of Tissue Engineering, R.G. Landes, Georgetown, TX, 1997.
4. [4] H. Sheardown, C. Wedge, L. Chou, R. Apel, D.S. Rootman, Y.-L. Cheng, Continuous epidermal growth factor delivery in corneal epithelial wound healing, Invest. Ophthalmol. Vis. Sci. 34 (1993) 3593-3600.
5. [5] N. Celebi, N. Erden, B. Gönül, M. Koz, Effects of epidermal growth factor dosage forms on dermal wound strength in mice, J. Pharm. Pharmacol. 46 (1994) 386-387.
6. [6] C.G. Craig, V. Tropepe, C.M. Morshead, B.A. Reynolds, S. Weiss, D.v.d. Kooy, In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain, J. Neurosci. 16 (1996) 2649-2658.
7. [7] A. Postlethwaite, J. Keski-Oja, H. Moses, A. Kang, Stimulation of the chemotactic migration of human fibroblasts by TGF-β, J. Exp. Med. 165 (1987) 251-256.
8. [8] J.H. Kordower, E.Y. Chen, E.J. Mufson, S.R. Winn, D.F. Emerich, Intrastriatal implants of polymer encapsulated cells genetically modified to secrete human nerve growth factor: Trophic effects upon cholinergic and noncholinergic striatal neurons, Neuroscience 72 (1996) 63-77.
9. [9] W.M. Saltzman, M.R. Parkhurst, J. Chun, M. Shin, CD18-dependent migration of neutrophils through collagen gels, submitted.
10. [10] Y. Lee, L.V. McIntire, K. Zygourakis, Analysis of endothelial cell locomotion: Differential effects of motility and contact inhibition, Biotechnol. Bioeng. 43 (1993) 622-634.
11. [11] D.A. Lauffenburger, J.J. Linderman, Receptors: Models for binding, trafficking, and signaling. Oxford University Press, New York, 1993, p. 365.
12. [12] S.H. Zigmond, Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors, J. Cell Biol. 75 (1977) 606-616.
13. [13] P. Parsons-Wingerter, Cooperativity in hepatocyte culture from cell-cell and cell-substrate interactions, Ph.D. thesis, The Johns Hopkins University, Chemical Engineering, Baltimore, MD, 1992.
14. [14] C. Yuasa, Y. Tomita, M. Shono, K. Ishimura, A. Ichihara, Importance of cell aggregation for expression of liver functions and regeneration demonstrated with primary cultured hepatocytes, J. Cell. Physiol. 156 (1993) 522-530.
15. [15] G. Flouriot, C. Vaillant, G. Salbert, C. Pelissero, J.M. Guiraud, Y. Valotaire, Monolayer and aggregate cultures of rainbow trout hepatocytes: long-term and stable liver-specific expression in aggregates, J. Cell Sci. 105 (1993) 407-416.
16. [16] M.D. Pierschbacher, E. Ruoslahti, Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule, Nature 309 (1984) 30-33.
17. [17] Y. Ito, M. Kajihara, Y. Imanishi, Materials for enhancing cell adhesion by immobilization of a cell-adhesive peptide, J. Biomed. Mater. Res. 25 (1991) 1325-1337.
18. [18] Y. Ito, Biocomposite materials for cell culture, in Y. Imanishi (Ed.), Synthesis of Biocomposite Materials, CRC Press, Boca Raton, FL, 1992.
19. [19] M.J. Moghaddam, T. Matsuda, Development of a 3-D artificial extracellular matrix, Trans Am Soc Artificial Internal Organs 37 (1991) M437-M438.
20. [20] S.P. Massia, J.A. Hubbell, Human endothelial cell interactions with surface-coupled adhesion peptides on a nonadhesive glass substrate and two polymeric biomaterials, J. Biomed. Mater. Res. 25 (1991) 223-242.
21. [21] N. Belcheva, S. Baldwin, W.M. Saltzman, Synthesis and characterization of polymer-(multi)-peptide conjugates for control of specific cell aggregation, J. Biomater. Sci., in press.
22. [22] W. Dai, J. Belt, W.M. Saltzman, Cell-binding peptides conjugated to poly(ethylene glycol) promote neural cell aggregation, Bio/Technology 12 (1994) 797-801.
23. [23] W. Dai, W. Saltzman, Fibroblast aggregation by suspension with conjugates of poly(ethylene glycol) and RGD, Biotechnol. Bioeng. 50 (1996) 349-356.
24. [24] J.L. Hill-West, S.M. Chowdhury, M.J. Slepian, J.A. Hubbell, Inhibition of thrombosis and initial thickening by in situ photopolymerization of thin hydrogel barriers, Proc. Natl. Acad. Sci. USA 91 (1994) 5967-5971.
25. [25] W.M. Saltzman, Growth factor delivery in tissue engineering, MRS Bull. 21 (1996) 62-65.
26. [26] B. Alberts, D. Bray, J. Lewis, M. Raff, K. Roberts, J.D. Watson (Eds). Molecular Biology of the Cell, third ed., Garland Publishing, New York, 1994, p. 1294.
27. [27] P.Y. Kuo, W.M. Saltzman, Novel systems for drug delivery of macromolecules, Crit. Rev. Eukaryotic Gene Expr. 6 (1996) 59-73.
28. [28] L.K. Fung, W.M. Saltzman, Polymeric implants for cancer chemotherapy, Adv. Drug Deliv. Rev. 0 (1997) 000-000.
29. [29] W.R. Gombotz, D.K. Pettit, Biodegradable polymers for protein and peptide drug delivery, Bioconj. Chem. 6 (1995) 332-351.
30. [30] R. Langer, New methods of drug delivery, Science 249 (1990) 1527-1533.
31. [31] J. Folkman, D. Long, The use of silicone rubber as a carrier for prolonged drug therapy, J. Surg. Res. 4 (1964) 139-142.
32. [32] J. Folkman, D. Long, R. Rosenbaum, Silicone rubber: a new diffusion property for general anesthesia, Science 154 (1966) 148-149.
33. [33] W.M. Saltzman, S.H. Pasternak, R. Langer, Quantitative image analysis for developing microstructural descriptions of heterogeneous materials, Chem. Eng. Sci. 42 (1987) 1989-2004.
34. [34] W.M. Saltzman, R. Langer, Transport rates of proteins in porous polymers with known microgeometry, Biophys. J. 55 (1989) 163-171.
35. [35] H. Okada, H. Toguchi, Biodegradable microspheres in drug delivery, Crit. Rev Ther. Drug Carrier Syst. 12 (1995) 1-99.
36. [36] C.E. Krewson, M. Klarman, W.M. Saltzman, Distribution of nerve growth factor following direct delivery to brain interstitium, Brain Res. 680 (1995) 196-206.
37. [37] C.E. Krewson, W.M. Saltzman, Transport and elimination of recombinant human NGF during long-term delivery to the brain, Brain Res. 727 (1996) 169-181.
38. [38] C.E. Krewson, W.M. Saltzman, Nerve growth factor delivery and cell aggregation enhance choline acetyltransferase activity after neural transplantation, Tissue Eng. 2 (1996) 183-196.
39. [39] E.R. Edelman, M.A. Nugent, M.J. Karnovsky, Perivascular and intravenous administration of basic fibroblast growth factor: Vascular and solid organ deposition, Proc. Natl. Acad. Sci. USA 90 (1993) 1513-1517.
40. [40] A. Lee, R. Langer, Shark cartilage contains inhibitors of tumor angiogenesis, Science 221 (1983) 1185-1187.
41. [41] C.E. Krewson, R.B. Dause, M.W. Mak, W.M. Saltzman, Stabilization of nerve growth factor in polymers and in tissues, J. Biomater. Sci. 8 (1996) 103-117.
42. [42] P.J. Camarata, R. Suryanarayanan, D.A. Turner, Sustained release of nerve growth factor from biodegradable polymer microspheres, Neurosurgery 30 (1992) 313-319.
43. [43] J. Cleland, E. Duenas, J. Yang, H. Chu, V. Mukku, A. Mac, M. Roussakis, D. Yeung, D. Brooks, Y.-F. Maa, C. Hsu, J. Jones, One month continuous release of recombinant human growth hormone-PLGA formulations, Proc. Int. Symp. Rel. Bioact. Mater. 22 (1995) 149-150.
44. [44] B. Gönül, D. Erdogan, C. Özogul, M. Koz, A. Babül, N. Çelebi, Effect of EGF dosage forms on alkali burned corneal wound healing in mice, Burns 21 (1995) 7-10.
45. [45] M. Oudega, X.M. Xu, V. Guénard, N. Kleitman, M.B. Bunge, A combination of insulin-like growth factor and platelet-derived growth factor enhances myelination but diminishes axonal regeneration into Schwann cell grafts in the adult rat spinal cords, Glia 19 (1997) 247-258.
46. [46] M.F. Charette, R.B. Rutherford, Regeneration of dentin, in R. Lanza, R. Langer (Eds), Principles of Tissue Engineering, R.G. Landes, Georgetown, TX, 1997, pp. 727-734.
47. [47] M.G. Cascone, B. Sim, S. Downes, Blends of synthetic and natural polymers as drug delivery systems for growth hormone, Biomaterials 16 (1995) 569-574.
48. [48] C. Krewson, R. Dause, M. Mak, W. Saltzman, Stabilization of nerve growth factor in controlled release polymers and in tissue, J. Biomater. Sci., Polymer Edition 8 (1996) 103-117.
49. [49] J.B. Murray, L. Brown, R. Langer, M. Klagsburn, A micro sustained release system for epidermal growth factor, In Vitro 19 (1983) 743-748.
50. [50] D. Gospodarowicz, J. Cheng, Heparin protects basic and acidic FGF from inactivation, J. Cell. Physiol. 128 (1986) 475-484.
51. [51] M. Loughnan, K. Chatzistefanou, E. Gonzalez, E. Flynn, A. Adamis, Y. Shing, R. D'Amato, J. Folkman, Experimental corneal neovascularisation using sucralfate and basic fibroblast growth factor, Aust. New Zealand J. Ophthalmol. 24 (1996) 289-295.
52. [52] T. Nicaeus, M. Tolentino, A. Adamis, P. Rubin, Sucralfate and basic fibroblast growth factor promote endothelial cell proliferation around porous alloplastic implants in vitro, Ophthalmic Plast. Reconstr. Surg. 12 (1996) 235-239.
53. [53] M.J. Mahoney, W.M. Saltzman, Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders, J. Pharm. Sci. 85 (1996) 1276-1281.
54. [54] W.M. Saltzman, M.L. Radomsky, Drugs released from polymers: diffusion and elimination in brain tissue, Chem. Eng. Sci. 46 (1991) 2429-2444.
55. [55] M.F. Haller, W.M. Saltzman, Localized delivery of proteins in the brain, Pharm. Res. 15 (1998) 377-385.
56. [56] W. Dang, W.M. Saltzman, Dextran retention in the rat brain following controlled release from a polymer, Biotechnol. Prog. 8 (1992) 527-532.
57. [57] W.M. Saltzman, Antibodies for treating and preventing disease: the potential role of polymeric controlled release, Crit. Rev. Ther. Drug Carrier Syst. 10 (1993) 111-142.
58. [58] W.B. Dang, O.M. Colvin, H. Brem, W.M. Saltzman, Covalent coupling of methotrexate to dextran enhances the penetration of cytotoxicity into a tissue-like matrix, Cancer Res. 54 (1994) 1729-1735.
59. [59] J.F. Strasser, L.K. Fung, S. Eller, S.A. Grossman, W.M. Saltzman, Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and tracers in the rabbit brain following interstitial delivery by biodegradable polymer implants, J. Pharmacol. Exp. Ther. 275 (1995) 1647-1655.
60. [60] L. Fung, M. Shin, B. Tyler, H. Brem, W.M. Saltzman, Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain, Pharm. Res. 13 (1996) 671-682.
61. [61] D. Knauer, H. Wiley, D. Cunningham, Relationship between epidermal growth factor receptor occupancy and mitogenic response: quantitative analysis using a steady-state model system, J. Biol. Chem. 259 (1984) 5623-5631.
62. [62] W. Driever, C. Nüsslein-Volhard, The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner, Cell 54 (1988) 95-104.
63. [63] D.S. Johnston, C. Nüsslein-Volhard, The origin of pattern and polarity in the Drosophila embryo, Cell 68 (1992) 201-219.
64. [64] C.M. Pai, Y.H. Bae, E. Mack, D. Wilson, S. Kim, Concanavalin A microspheres for a self-regulating insulin delivery system, J. Pharm. Sci. 81 (1992) 532-536.
65. [65] M. Brownlee, A. Cerami, A glucose-controlled insulin-delivery system: Semisynthetic insulin bound to lectin, Science 206 (1979) 1190-1191.
66. [66] J. Kost, T. Horbett, B. Ratner, M. Singh, Glucose-sensitive membranes containing glucose oxidase: Activity, swelling, and permeability studies, J. Biomed. Mater. Res. 19 (1985) 1117-1133.
67. [67] T. Maki, C.S. Ubhi, H. Sanchez-Farpon, S.J. Sullivan, K. Borland, T.E. Muller, B.A. Solomon, W.L. Chick, A.P. Monaco, Successful treatment of diabetes with the biohybrid artificial pancreas in dogs, Transplantation 51 (1991) 43-51.
68. [68] S.J. Sullivan, T. Maki, K.M. Borland, M.D. Mahoney, B.A. Solomon, T.E. Muller, A.P. Monaco, W.L. Chick, Biohybrid artificial pancreas: long-term implantation studies in diabetic, pancreatectomized dogs, Science 525 (1991) 718-721.
69. [69] H. Iwata, T. Takagi, K. Kobayashi, T. Oka, T. Tsuji, F. Ito, Strategy for developing microbeads applicable to islet xenotransplantation into a spontaneous diabetic NOD mouse, J. Biomed. Mater. Res. 28 (1994) 1201-1207.
70. [70] A.S. Sawhney, C.P. Pathak, J.A. Hubbell, Modification of islet of Langerhans surfaces with immunoprotective poly-(ethylene glycol) coatings via interfacial photopolymerization, Biotechnol. Bioeng. 44 (1994) 383-386.
71. [71] C.B. Jaeger, P. Aebischer, P.A. Tresco, S.R. Winn, L.A. Greene, Growth of tumor cell lines in polymer capsules: ultrastructure of encapsulated PC12 cells, J. Neurocytol. 21 (1992) 469-480.
72. [72] S.R. Winn, P.A. Tresco, B. Zielinski, L.A. Greene, C.B. Jaeger, P. Aebischer, Behavioral recovery following intrastriatal implantation of microencapsulated PC12 cells, Exp. Neurol. 113 (1991) 322-329.
73. [73] M.D. Lindner, S.R. Winn, E.E. Baetge, J.P. Hammang, F.T. Gentile, D. Doherty, P.E. McDermott, B. Frydel, M.D. Ullman, T. Schallert, D.F. Emerich, Implantation of encapsulated catecholamine and GDNF-producing cells in rats with unilateral dopamine depletions and Parkinsonian symptoms, Exp. Neurol. 132 (1995) 62-76.
74. [74] M. Schinstine, D.M. Fiore, S.R. Winn, D.F. Emerich, Polymer-encapsulated Schwannoma cells expressing human nerve growth factor promote the survival of cholinergic neurons after a fimbria-fornix transection, Cell Transplant. 4 (1995) 93-102.
75. [75] I. Date, T. Ohomoto, T. Imaoka, T. Shingo, Chromaffin cell survival from both young and old donors is enhanced by co-grafts of polymer-encapsulated human NGF-secreting-cells, NeuroReport 7 (1996) 1813-1818.
76. [76] D.A. Lauffenburger, J.J. Linderman, Receptors: models for binding, trafficking, and signaling, Oxford University Press, New York, 1993, 365 pp.
77. [77] Y. Ito, S. Kondo, G. Chen, Y. Imanshi, Patterned artificial juxtacrine stimulation of the cells by covalently immobilized insulin, FEBS Lett. 403 (1997) 159-162.
78. [78] P. Cuatercasas, Interaction of insulin with the cell membrane: the primary action of insulin, Proc. Natl. Acad. Sci. 63 (1969) 450-457.
79. [79] W.A. Frazier, L.F. Boyd, R.A. Bradshaw, Interaction of nerve growth factor with surface membranes: Biological competence of insoluble nerve growth factor, Proc. Natl. Acad. Sci. USA 79 (1973) 2931-2935.
80. [80] Y. Ito, S.Q. Liu, Y. Imanishi, Enhancement of cell growth on growth factor-immobilized polymer film, Biomaterials 12 (1991) 449-453.
81. [81] Y. Ito, M. Inoue, S.Q. Liu, Y. Imanishi, Cell growth on immobilized cell growth factor. 6. Enhancement of fibroblast cell growth by immobilized insulin and/or fibronectin, J. Biomed. Mater. Res. 27 (1993) 901-907.
82. [82] P.R. Kuhl, L.G. Griffith-Cima, Tethered epidermal growth factor as a paradigm for growth factor-induced stimulation from the solid phase, Nat. Med. 2 (1996) 1022-1027.
83. [83] C.C. Reddy, A. Wells, D.A. Lauffenburger, Proliferative response of fibroblasts expressing internalization-deficient epidermal growth factor (EGF) receptor is altered via differential EGF depletion effect, Biotechnol. Prog. 10 (1994) 377-384.
84. [84] R. Duncan, F. Spreafico, Polymer conjugates. Pharmacokinetic considerations for design and development, Clin. Pharmacokinet. 27 (1994) 290-306.
85. [85] C.K. Krewson, M.L. Klarman, W.M. Saltzman, Distribution of nerve growth factor following direct delivery to brain interstitum, Brain Res. 680 (1995) 196-206.
86. [86] W. Dang, O.M. Colvin, H. Brem, W.M. Saltzman, Covalent coupling of methotrexate to dextran enhances the penetration of cytotoxicity into a tissue-like matrix, Cancer Res. 54 (1994) 1729-1735.
87. [87] A.M. Felix, Y. Lu, R.M. Campbell, Pegylated peptides IV: Enhanced biological activity of site directed pegylated GRF analogs, Int. J. Pept. Protein Res. 46 (1995) 253-264.
88. [88] S.P. Massia, J.A. Hubbell, Covalent surface immobilization of Arg-Gly-Asp-and Tyr-Ile-Gly-Ser-Arg-containing peptides to obtain well-defined cell-adhesive substrates, Anal. Biochem. 187 (1990) 292-301.
89. [89] J. Wolff, R. Malone, P. Williams, W. Chong, G. Acsadi, A. Jani, P. Felgner, Direct gene transfer into mouse muscle in vivo, Science 247 (1990) 1465-1468.
90. [90] P. Felgner, Nonviral strategies for gene therapy, Scientific American 276 (1997) 102-106.
91. [91] M. Tang, C. Redemann, F. Szoka Jr., In vitro gene delivery by degraded polyamidoamine dendrimers, Bioconjugate 7 (1996) 703-714.
92. [92] E. Mathiowitz, J. Jacob, Y. Jong, G. Carino, D. Chickering, P. Chaturvedi, C. Santos, K. Vijayaraghavan, S. Montgomery, M. Bassett, C. Morrell, Biologically erodable microspheres as potential oral drug delivery systems, Nature 386 (1997) 410-414.
93. [93] J. Isner, A. Pieczek, R. Schainfeld, R. Blair, L. Haley, T. Asahara, K. Rosenfield, S. Razvi, K. Walsh, J. Symes, Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb, Lancet 348 (1996) 370-374.
94. [94] S.J. Konturek, W. Pawlik, W. Mysh, P. Gustaw, R. Sendur, E. Mikos, W. Bielanski, Comparison of organ uptake and disappearance half-time of human epidermal growth factor and insulin, Regul. Pept. 30 (1990) 137-148.
95. [95] V. Lindner, D. Lappi, A. Baird, R. Majack, M. Reidy, Role of basic fibroblast growth factor in vascular lesion formation, Circ. Res. 68 (1991) 106-113.
96. [96] J.H. Kordower, T.B. Freeman, B.J. Snow, F.J.G. Vingerhoets, E.J. Mufson, Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease, New Engl. J. Med. 332 (1995) 1118-1124.
97. [97] D. Kolson, J. Buchhalter, R. Collman, B. Hellmig, C. Farrell, C. Debouck, F. Gonzalez-Scarano, HIV-1 tat alters normal organization of neurons and astrocytes in primary rodent brain cell cultures: RGD sequence dependence, AIDS Res. Hum. Retroviruses 9 (1993) 677-685.
98. [98] B. Axelsson, R. Youseffi-Etemad, S. Hammarstrom, P. Perlmann, Induction of aggregation and enhancement of proliferation and IL-2 secretion in human T cells by antibodies to CD43, J. Immunol. 141 (1988) 2912-2917.
99. [99] M.J. Orsini, C.M. Debouck, C.L. Webb, P.G. Lysko, Extracellular human immunodeficiency virus type 1 tat protein promotes aggregation and adhesion of cerebellar neurons, J. Neurosci. 16 (1996) 2546-2552.