메뉴 건너뛰기




Volumn 8, Issue 3, 2006, Pages

Issues related to targeted delivery of proteins and peptides

Author keywords

Cancer therapy; Peptide therapeutics; Protein therapeutics; Targeted delivery

Indexed keywords

ANTICOAGULANT AGENT; BACTERIAL TOXIN; BLOOD CLOTTING FACTOR; CETUXIMAB; CYTOKINE; DENILEUKIN DIFTITOX; DIPHTHERIA TOXIN; DOXORUBICIN; EPIDERMAL GROWTH FACTOR; GELONIN; GEMTUZUMAB OZOGAMICIN; GONADORELIN; GRANULOCYTE COLONY STIMULATING FACTOR; GROWTH FACTOR; HORMONE; IBRITUMOMAB TIUXETAN; INTERLEUKIN 2; LUTEINIZING HORMONE; MONOCLONAL ANTIBODY; PEPTIDE DERIVATIVE; PLANT TOXIN; PROTEIN DERIVATIVE; PSEUDOMONAS EXOTOXIN; RICIN; RITUXIMAB; SOMATOSTATIN; TOSITUMOMAB I 131; TRASTUZUMAB; UNINDEXED DRUG; VASCULOTROPIN;

EID: 33746644192     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/aapsj080355     Document Type: Review
Times cited : (87)

References (110)
  • 1
    • 0038387390 scopus 로고    scopus 로고
    • The dawning era of polymer therapeutics
    • Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov. 2003;2:347-360.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 347-360
    • Duncan, R.1
  • 2
    • 0036488496 scopus 로고    scopus 로고
    • Specialization of tumour vasculature
    • Ruoslahti E. Specialization of tumour vasculature. Nat Rev Cancer. 2002;2:83-90.
    • (2002) Nat Rev Cancer , vol.2 , pp. 83-90
    • Ruoslahti, E.1
  • 3
    • 0035291191 scopus 로고    scopus 로고
    • SMANCS and polymer-conjugated macromolecular drugs: Advantages in cancer chemotherapy
    • Maeda H. SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy. Adv Drug Deliv Rev. 2001;46:169-185.
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 169-185
    • Maeda, H.1
  • 4
    • 0032739426 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone analogs: Their impact on the control of tumorigenesis
    • Schally AV. Luteinizing hormone-releasing hormone analogs: their impact on the control of tumorigenesis. Peptides. 1999;20:1247-1262.
    • (1999) Peptides , vol.20 , pp. 1247-1262
    • Schally, A.V.1
  • 5
  • 6
    • 15244351004 scopus 로고    scopus 로고
    • Overview of monoclonal antibodies in cancer therapy: Present and promise
    • Stern M, Herrmann R. Overview of monoclonal antibodies in cancer therapy: present and promise. Crit Rev Oncol Hematol. 2005;54:11-29.
    • (2005) Crit Rev Oncol Hematol , vol.54 , pp. 11-29
    • Stern, M.1    Herrmann, R.2
  • 7
    • 0024849184 scopus 로고
    • Immunotoxins: A clinical review of their use in the treatment of malignancies
    • Hertler AA, Frankel AE. Immunotoxins: a clinical review of their use in the treatment of malignancies. J Clin Oncol. 1989;7:1932-1942.
    • (1989) J Clin Oncol , vol.7 , pp. 1932-1942
    • Hertler, A.A.1    Frankel, A.E.2
  • 8
    • 0034001076 scopus 로고    scopus 로고
    • Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies
    • Kreitman RJ, Wilson WH, White JD, et al. Phase I trial of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) in patients with hematologic malignancies. J Clin Oncol. 2000;18:1622-1636.
    • (2000) J Clin Oncol , vol.18 , pp. 1622-1636
    • Kreitman, R.J.1    Wilson, W.H.2    White, J.D.3
  • 9
    • 0035954624 scopus 로고    scopus 로고
    • Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia
    • Kreitman RJ, Wilson WH, Bergeron K, et al. Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia. N Engl J Med. 2001;345:241-247.
    • (2001) N Engl J Med , vol.345 , pp. 241-247
    • Kreitman, R.J.1    Wilson, W.H.2    Bergeron, K.3
  • 10
    • 10744219583 scopus 로고    scopus 로고
    • Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors
    • Sampson JH, Akabani G, Archer GE, et al. Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. J Neurooncol. 2003;65:27-35.
    • (2003) J Neurooncol , vol.65 , pp. 27-35
    • Sampson, J.H.1    Akabani, G.2    Archer, G.E.3
  • 11
    • 0344876636 scopus 로고    scopus 로고
    • Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas
    • Weaver M, Laske DW. Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas. J Neurooncol. 2003;65:3-13.
    • (2003) J Neurooncol , vol.65 , pp. 3-13
    • Weaver, M.1    Laske, D.W.2
  • 12
    • 0027423248 scopus 로고
    • Cytotoxicity of folate-Pseudomonas exotoxin conjugates toward tumor cells. Contribution of translocation domain
    • Leamon CP, Pastan I, Low PS. Cytotoxicity of folate-Pseudomonas exotoxin conjugates toward tumor cells. Contribution of translocation domain. J Biol Chem. 1993;268:24847-24854.
    • (1993) J Biol Chem , vol.268 , pp. 24847-24854
    • Leamon, C.P.1    Pastan, I.2    Low, P.S.3
  • 13
    • 0028301330 scopus 로고
    • Selective targeting of malignant cells with cytotoxin-folate conjugates
    • Leamon CP, Low PS. Selective targeting of malignant cells with cytotoxin-folate conjugates. J Drug Target. 1994;2:101-112.
    • (1994) J Drug Target , vol.2 , pp. 101-112
    • Leamon, C.P.1    Low, P.S.2
  • 14
    • 0035958878 scopus 로고    scopus 로고
    • Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells
    • Atkinson SF, Bettinger T, Seymour LW, et al. Conjugation of folate via gelonin carbohydrate residues retains ribosomal-inactivating properties of the toxin and permits targeting to folate receptor positive cells. J Biol Chem. 2001;276:27930-27935.
    • (2001) J Biol Chem , vol.276 , pp. 27930-27935
    • Atkinson, S.F.1    Bettinger, T.2    Seymour, L.W.3
  • 15
    • 0036098391 scopus 로고    scopus 로고
    • Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia
    • Frankel AE, Powell BL, Hall PD, et al. Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia. Clin Cancer Res. 2002;8:1004-1013.
    • (2002) Clin Cancer Res , vol.8 , pp. 1004-1013
    • Frankel, A.E.1    Powell, B.L.2    Hall, P.D.3
  • 16
    • 8744295088 scopus 로고    scopus 로고
    • Antibody-directed enzyme prodrug therapy (ADEPT) for cancer
    • Bagshawe KD, Sharma SK, Begent RH. Antibody-directed enzyme prodrug therapy (ADEPT) for cancer. Expert Opin Biol Ther. 2004;4:1777-1789.
    • (2004) Expert Opin Biol Ther , vol.4 , pp. 1777-1789
    • Bagshawe, K.D.1    Sharma, S.K.2    Begent, R.H.3
  • 17
    • 18544390790 scopus 로고    scopus 로고
    • A phase I trial of antibody directed enzyme prodrug therapy (ADEPT) in patients with advanced colorectal carcinoma or other CEA producing tumours
    • Francis RJ, Sharma SK, Springer C, et al. A phase I trial of antibody directed enzyme prodrug therapy (ADEPT) in patients with advanced colorectal carcinoma or other CEA producing tumours. Br J Cancer. 2002;87:600-607.
    • (2002) Br J Cancer , vol.87 , pp. 600-607
    • Francis, R.J.1    Sharma, S.K.2    Springer, C.3
  • 18
    • 0037017864 scopus 로고    scopus 로고
    • A fully human anti-EpCAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug
    • de Graaf M, Boven E, Oosterhoff D, et al. A fully human anti-EpCAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug. Br J Cancer. 2002;86:811-818.
    • (2002) Br J Cancer , vol.86 , pp. 811-818
    • de Graaf, M.1    Boven, E.2    Oosterhoff, D.3
  • 19
    • 0038792727 scopus 로고    scopus 로고
    • A novel vascular endothelial growth factor-directed therapy that selectively activates cytotoxic prodrugs
    • Spooner RA, Friedlos F, Maycroft K, et al. A novel vascular endothelial growth factor-directed therapy that selectively activates cytotoxic prodrugs. Br J Cancer. 2003;88:1622-1630.
    • (2003) Br J Cancer , vol.88 , pp. 1622-1630
    • Spooner, R.A.1    Friedlos, F.2    Maycroft, K.3
  • 20
    • 0032873312 scopus 로고    scopus 로고
    • Folate-targeted enzyme prodrug cancer therapy utilizing penicillin-V amidase and a doxorubicin prodrug
    • Lu JY, Lowe DA, Kennedy MD, Low PS. Folate-targeted enzyme prodrug cancer therapy utilizing penicillin-V amidase and a doxorubicin prodrug. J Drug Target. 1999;7:43-53.
    • (1999) J Drug Target , vol.7 , pp. 43-53
    • Lu, J.Y.1    Lowe, D.A.2    Kennedy, M.D.3    Low, P.S.4
  • 21
    • 5144232846 scopus 로고    scopus 로고
    • LEAPT: Lectin-directed enzyme-activated prodrug therapy
    • Robinson MA, Charlton ST, Garnier P, et al. LEAPT: lectin-directed enzyme-activated prodrug therapy. Proc Natl Acad Sci USA. 2004;101:14527-14532.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14527-14532
    • Robinson, M.A.1    Charlton, S.T.2    Garnier, P.3
  • 22
    • 0042666808 scopus 로고    scopus 로고
    • Preclinical and clinical development of immunocytokines
    • Sondel PM, Hank JA, Gan J, et al. Preclinical and clinical development of immunocytokines. Curr Opin Investig Drugs. 2003;4:696-700.
    • (2003) Curr Opin Investig Drugs , vol.4 , pp. 696-700
    • Sondel, P.M.1    Hank, J.A.2    Gan, J.3
  • 23
    • 4344630984 scopus 로고    scopus 로고
    • Ex vivo evaluation of anti-EpCAM immunocytokine huKS-IL2 in ovarian cancer
    • Connor JP, Felder M, Hank J, et al. Ex vivo evaluation of anti-EpCAM immunocytokine huKS-IL2 in ovarian cancer. J Immunother. 2004;27:211-219.
    • (2004) J Immunother , vol.27 , pp. 211-219
    • Connor, J.P.1    Felder, M.2    Hank, J.3
  • 24
    • 18544371520 scopus 로고    scopus 로고
    • An anti-CD20-IL-2 immunocytokine is highly efficacious in a SCID mouse model of established human B lymphoma
    • Gillies SD, Lan Y, Williams S, et al. An anti-CD20-IL-2 immunocytokine is highly efficacious in a SCID mouse model of established human B lymphoma. Blood. 2005;105:3972-3978.
    • (2005) Blood , vol.105 , pp. 3972-3978
    • Gillies, S.D.1    Lan, Y.2    Williams, S.3
  • 25
    • 0032530237 scopus 로고    scopus 로고
    • Targeting of interleukin 2 to human ovarian carcinoma by fusion with a single-chain Fv of antifolate receptor antibody
    • Melani C, Figini M, Nicosia D, et al. Targeting of interleukin 2 to human ovarian carcinoma by fusion with a single-chain Fv of antifolate receptor antibody. Cancer Res. 1998;58:4146-4154.
    • (1998) Cancer Res , vol.58 , pp. 4146-4154
    • Melani, C.1    Figini, M.2    Nicosia, D.3
  • 26
    • 0036625059 scopus 로고    scopus 로고
    • Antidisialoganglioside/granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcgammaRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis
    • Metelitsa LS, Gillies SD, Super M, et al. Antidisialoganglioside/ granulocyte macrophage-colony-stimulating factor fusion protein facilitates neutrophil antibody-dependent cellular cytotoxicity and depends on FcgammaRII (CD32) and Mac-1 (CD11b/CD18) for enhanced effector cell adhesion and azurophil granule exocytosis. Blood. 2002;99:4166-4173.
    • (2002) Blood , vol.99 , pp. 4166-4173
    • Metelitsa, L.S.1    Gillies, S.D.2    Super, M.3
  • 27
    • 23844436915 scopus 로고    scopus 로고
    • The immunocytokine scFv23/TNF sensitizes HER-2/neu-overexpressing SKBR-3 cells to tumor necrosis factor (TNF) via up-regulation of TNF receptor-1
    • Lyu MA, Rosenblum MG. The immunocytokine scFv23/TNF sensitizes HER-2/ neu-overexpressing SKBR-3 cells to tumor necrosis factor (TNF) via up-regulation of TNF receptor-1. Mol Cancer Ther. 2005;4:1205-1213.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1205-1213
    • Lyu, M.A.1    Rosenblum, M.G.2
  • 28
    • 0035874549 scopus 로고    scopus 로고
    • Targeting of a B7-1 (CD80) immunoglobulin G fusion protein to acute myeloid leukemia blasts increases their costimulatory activity for autologous remission T cells
    • Notter M, Willinger T, Erben U, Thiel E. Targeting of a B7-1 (CD80) immunoglobulin G fusion protein to acute myeloid leukemia blasts increases their costimulatory activity for autologous remission T cells. Blood. 2001;97:3138-3145.
    • (2001) Blood , vol.97 , pp. 3138-3145
    • Notter, M.1    Willinger, T.2    Erben, U.3    Thiel, E.4
  • 29
    • 0042526640 scopus 로고    scopus 로고
    • The immunogenicity of biopharmaceuticals. Lessons learned and consequences for protein drug development
    • Patten PA, Schellekens H. The immunogenicity of biopharmaceuticals. Lessons learned and consequences for protein drug development. Dev Biol (Basel). 2003;112:81-97.
    • (2003) Dev Biol (Basel) , vol.112 , pp. 81-97
    • Patten, P.A.1    Schellekens, H.2
  • 30
  • 31
    • 0035014185 scopus 로고    scopus 로고
    • Directed evolution of proteins by exon shuffling
    • Kolkman JA, Stemmer WP. Directed evolution of proteins by exon shuffling. Nat Biotechnol. 2001;19:423-428.
    • (2001) Nat Biotechnol , vol.19 , pp. 423-428
    • Kolkman, J.A.1    Stemmer, W.P.2
  • 32
    • 0036861899 scopus 로고    scopus 로고
    • Immunogenicity of therapeutic proteins: Clinical implications and future prospects
    • Discussion 1719
    • Schellekens H. Immunogenicity of therapeutic proteins: clinical implications and future prospects. Clin Ther. 2002;24:1720-1740. Discussion 1719.
    • (2002) Clin Ther , vol.24 , pp. 1720-1740
    • Schellekens, H.1
  • 33
    • 0344420226 scopus 로고    scopus 로고
    • Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates
    • Caliceti P, Veronese FM. Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates. Adv Drug Deliv Rev. 2003;55:1261-1277.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 1261-1277
    • Caliceti, P.1    Veronese, F.M.2
  • 35
    • 0025777450 scopus 로고
    • Hepatic disposition characteristics of electrically charged macromolecules in rat in vivo and in the perfused liver
    • Nishida K, Mihara K, Takino T, et al. Hepatic disposition characteristics of electrically charged macromolecules in rat in vivo and in the perfused liver. Pharm Res. 1991;8:437-444.
    • (1991) Pharm Res , vol.8 , pp. 437-444
    • Nishida, K.1    Mihara, K.2    Takino, T.3
  • 36
    • 0028998769 scopus 로고
    • The asialoglycoprotein receptor: Relationships Retween structure, function, and expression
    • Stockert RJ. The asialoglycoprotein receptor: relationships between structure, function, and expression. Physiol Rev. 1995;75:591-609.
    • (1995) Physiol Rev , vol.75 , pp. 591-609
    • Stockert, R.J.1
  • 37
    • 17044367510 scopus 로고    scopus 로고
    • Use of multiple biomarkers for a molecular diagnosis of prostate cancer
    • Landers KA, Burger MJ, Tebay MA, et al. Use of multiple biomarkers for a molecular diagnosis of prostate cancer. Int J Cancer. 2005;114:950-956.
    • (2005) Int J Cancer , vol.114 , pp. 950-956
    • Landers, K.A.1    Burger, M.J.2    Tebay, M.A.3
  • 38
    • 0031042591 scopus 로고    scopus 로고
    • Prostate-specific membrane antigen expression in normal and malignant human tissues
    • Silver DA, Pellicer I, Fair WR, et al. Prostate-specific membrane antigen expression in normal and malignant human tissues. Clin Cancer Res. 1997;3:81-85.
    • (1997) Clin Cancer Res , vol.3 , pp. 81-85
    • Silver, D.A.1    Pellicer, I.2    Fair, W.R.3
  • 39
    • 0032428353 scopus 로고    scopus 로고
    • Molecular characterization of human brain N-acetylated alpha-linked acidic dipeptidase (NAALADase)
    • Luthi-Carter R, Barczak AK, Speno H, Coyle JT. Molecular characterization of human brain N-acetylated alpha-linked acidic dipeptidase (NAALADase). J Pharmacol Exp Ther. 1998;286:1020-1025.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1020-1025
    • Luthi-Carter, R.1    Barczak, A.K.2    Speno, H.3    Coyle, J.T.4
  • 40
    • 0037072555 scopus 로고    scopus 로고
    • Folate-mediated delivery of macromolecular anticancer therapeutic agents
    • Lu Y, Low PS. Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv Drug Deliv Rev. 2002;54: 675-693.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 675-693
    • Lu, Y.1    Low, P.S.2
  • 41
    • 0036331190 scopus 로고    scopus 로고
    • Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells
    • Mastrobattista E, Crommelin DJ, Wilschut J, Storm G. Targeted liposomes for delivery of protein-based drugs into the cytoplasm of tumor cells. J Liposome Res. 2002;12:57-65.
    • (2002) J Liposome Res , vol.12 , pp. 57-65
    • Mastrobattista, E.1    Crommelin, D.J.2    Wilschut, J.3    Storm, G.4
  • 42
    • 0035066562 scopus 로고    scopus 로고
    • Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands
    • Becker A, Hessenius C, Licha K, et al. Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands. Nat Biotechnol. 2001;19:327-331.
    • (2001) Nat Biotechnol , vol.19 , pp. 327-331
    • Becker, A.1    Hessenius, C.2    Licha, K.3
  • 44
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 45
    • 0035878997 scopus 로고    scopus 로고
    • Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470
    • Ma J, Pulfer S, Li S, et al. Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470. Cancer Res. 2001;61:5491-5498.
    • (2001) Cancer Res , vol.61 , pp. 5491-5498
    • Ma, J.1    Pulfer, S.2    Li, S.3
  • 46
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain RK. Molecular regulation of vessel maturation. Nat Med. 2003;9:685-693.
    • (2003) Nat Med , vol.9 , pp. 685-693
    • Jain, R.K.1
  • 47
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science. 2005;307:58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 48
    • 9444260479 scopus 로고    scopus 로고
    • Biological impediments to monoclonal antibody-based cancer immunotherapy
    • Christiansen J, Rajasekaran AK. Biological impediments to monoclonal antibody-based cancer immunotherapy. Mol Cancer Ther. 2004;3:1493-1501.
    • (2004) Mol Cancer Ther , vol.3 , pp. 1493-1501
    • Christiansen, J.1    Rajasekaran, A.K.2
  • 49
    • 0036678474 scopus 로고    scopus 로고
    • Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration
    • Curnis F, Sacchi A, Corti A. Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration. J Clin Invest. 2002;110:475-482.
    • (2002) J Clin Invest , vol.110 , pp. 475-482
    • Curnis, F.1    Sacchi, A.2    Corti, A.3
  • 50
    • 1642434101 scopus 로고    scopus 로고
    • Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity
    • Curnis F, Gasparri A, Sacchi A, et al. Coupling tumor necrosis factor-alpha with alphaV integrin ligands improves its antineoplastic activity. Cancer Res. 2004;64:565-571.
    • (2004) Cancer Res , vol.64 , pp. 565-571
    • Curnis, F.1    Gasparri, A.2    Sacchi, A.3
  • 51
    • 0024433856 scopus 로고
    • Modeling analysis of the global and microscopic distribution of immunoglobulin G, F(ab')2, and Fab in tumors
    • Fujimori K, Covell DG, Fletcher JE, Weinstein JN. Modeling analysis of the global and microscopic distribution of immunoglobulin G, F(ab')2, and Fab in tumors. Cancer Res. 1989;49:5656-5663.
    • (1989) Cancer Res , vol.49 , pp. 5656-5663
    • Fujimori, K.1    Covell, D.G.2    Fletcher, J.E.3    Weinstein, J.N.4
  • 52
    • 0026739369 scopus 로고
    • Micropharmacology of monoclonal antibodies in solid tumors: Direct experimental evidence for a binding site barrier
    • Juweid M, Neumann R, Paik C, et al. Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier. Cancer Res. 1992;52:5144-5153.
    • (1992) Cancer Res , vol.52 , pp. 5144-5153
    • Juweid, M.1    Neumann, R.2    Paik, C.3
  • 53
    • 0035874887 scopus 로고    scopus 로고
    • High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules
    • Adams GP, Schier R, McCall AM, et al. High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules. Cancer Res. 2001;61:4750-4755.
    • (2001) Cancer Res , vol.61 , pp. 4750-4755
    • Adams, G.P.1    Schier, R.2    McCall, A.M.3
  • 54
    • 0026675266 scopus 로고
    • Comparisons between two monoclonal antibodies that bind to the same antigen but have differing affinities: Uptake kinetics and 125I-antibody therapy efficacy in multicell spheroids
    • Langmuir VK, Mendonca HL, Woo DV. Comparisons between two monoclonal antibodies that bind to the same antigen but have differing affinities: uptake kinetics and 125I-antibody therapy efficacy in multicell spheroids. Cancer Res. 1992;52:4728-4734.
    • (1992) Cancer Res , vol.52 , pp. 4728-4734
    • Langmuir, V.K.1    Mendonca, H.L.2    Woo, D.V.3
  • 55
    • 0029114671 scopus 로고
    • Targeting cancer micrometastases with monoclonal antibodies: A binding-site barrier
    • Saga T, Neumann RD, Heya T, et al. Targeting cancer micrometastases with monoclonal antibodies: a binding-site barrier. Proc Natl Acad Sci USA. 1995;92:8999-9003.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8999-9003
    • Saga, T.1    Neumann, R.D.2    Heya, T.3
  • 56
    • 0033805101 scopus 로고    scopus 로고
    • Effect of therapeutic macromolecules in spheroids
    • Fracasso G, Colombatti M. Effect of therapeutic macromolecules in spheroids. Crit Rev Oncol Hematol. 2000;36:159-178.
    • (2000) Crit Rev Oncol Hematol , vol.36 , pp. 159-178
    • Fracasso, G.1    Colombatti, M.2
  • 57
    • 0037444270 scopus 로고    scopus 로고
    • Theoretical analysis of antibody targeting of tumor spheroids: Importance of dosage for penetration, and affinity for retention
    • Graff CP, Wittrup KD. Theoretical analysis of antibody targeting of tumor spheroids: importance of dosage for penetration, and affinity for retention. Cancer Res. 2003;63:1288-1296.
    • (2003) Cancer Res , vol.63 , pp. 1288-1296
    • Graff, C.P.1    Wittrup, K.D.2
  • 58
    • 13444263549 scopus 로고    scopus 로고
    • Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
    • Le Roy C, Wrana JL. Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat Rev Mol Cell Biol. 2005;6: 112-126.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 112-126
    • Le Roy, C.1    Wrana, J.L.2
  • 59
    • 0025951931 scopus 로고
    • Delivery of macromolecules into living cells: A method that exploits folate receptor endocytosis
    • Leamon CP, Low PS. Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis. Proc Natl Acad Sci USA. 1991;88:5572-5576.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5572-5576
    • Leamon, C.P.1    Low, P.S.2
  • 60
    • 0025760491 scopus 로고
    • Uptake and concentration of bioactive macromolecules by K562 cells via the transferrin cycle utilizing an acid-labile transferrin conjugate
    • Wellhoner HH, Jr, Neville DM, Jr, Srinivasachar K, Erdmann G. Uptake and concentration of bioactive macromolecules by K562 cells via the transferrin cycle utilizing an acid-labile transferrin conjugate. J Biol Chem. 1991;266:4309-4314.
    • (1991) J Biol Chem , vol.266 , pp. 4309-4314
    • Wellhoner Jr., H.H.1    Neville Jr., D.M.2    Srinivasachar, K.3    Erdmann, G.4
  • 61
    • 12244309511 scopus 로고    scopus 로고
    • Smart polymeric carriers for enhanced intracellular delivery of therapeutic macromolecules
    • El-Sayed ME, Hoffman AS, Stayton PS. Smart polymeric carriers for enhanced intracellular delivery of therapeutic macromolecules. Expert Opin Biol Ther. 2005;5:23-32.
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 23-32
    • El-Sayed, M.E.1    Hoffman, A.S.2    Stayton, P.S.3
  • 62
    • 0037178877 scopus 로고    scopus 로고
    • Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins
    • Mastrobattista E, Koning GA, van Bloois L, et al. Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins. J Biol Chem. 2002;277:27135-27143.
    • (2002) J Biol Chem , vol.277 , pp. 27135-27143
    • Mastrobattista, E.1    Koning, G.A.2    van Bloois, L.3
  • 63
    • 2442421428 scopus 로고    scopus 로고
    • Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: An artificial viral-like delivery system
    • Kakudo T, Chaki S, Futaki S, et al. Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system. Biochemistry. 2004;43:5618-5628.
    • (2004) Biochemistry , vol.43 , pp. 5618-5628
    • Kakudo, T.1    Chaki, S.2    Futaki, S.3
  • 64
    • 0033559618 scopus 로고    scopus 로고
    • Photochemical internalization: A novel technology for delivery of macromolecules into cytosol
    • Berg K, Selbo PK, Prasmickaite L, et al. Photochemical internalization: a novel technology for delivery of macromolecules into cytosol. Cancer Res. 1999;59:1180-1183.
    • (1999) Cancer Res , vol.59 , pp. 1180-1183
    • Berg, K.1    Selbo, P.K.2    Prasmickaite, L.3
  • 65
    • 0035371749 scopus 로고    scopus 로고
    • In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
    • Selbo PK, Sivam G, Fodstad O, et al. In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy. Int J Cancer. 2001;92:761-766.
    • (2001) Int J Cancer , vol.92 , pp. 761-766
    • Selbo, P.K.1    Sivam, G.2    Fodstad, O.3
  • 66
    • 0033844659 scopus 로고    scopus 로고
    • Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
    • Selbo PK, Sivam G, Fodstad O, et al. Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin. Int J Cancer. 2000;87:853-859.
    • (2000) Int J Cancer , vol.87 , pp. 853-859
    • Selbo, P.K.1    Sivam, G.2    Fodstad, O.3
  • 67
    • 0346729779 scopus 로고    scopus 로고
    • Photochemical internalisation in drug and gene delivery
    • Hogset A, Prasmickaite L, Selbo PK, et al. Photochemical internalisation in drug and gene delivery. Adv Drug Deliv Rev. 2004;56:95-115.
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 95-115
    • Hogset, A.1    Prasmickaite, L.2    Selbo, P.K.3
  • 68
    • 0032756159 scopus 로고    scopus 로고
    • Angiogenesis and cancer control: From concept to therapeutic trial
    • Brem S. Angiogenesis and cancer control: from concept to therapeutic trial. Cancer Control. 1999;6:436-458.
    • (1999) Cancer Control , vol.6 , pp. 436-458
    • Brem, S.1
  • 69
    • 0036257686 scopus 로고    scopus 로고
    • Converting a peptide into a drug: Strategies to improve stability and bioavailability
    • Adessi C, Soto C. Converting a peptide into a drug: strategies to improve stability and bioavailability. Curr Med Chem. 2002;9:963-978.
    • (2002) Curr Med Chem , vol.9 , pp. 963-978
    • Adessi, C.1    Soto, C.2
  • 70
    • 0343294352 scopus 로고    scopus 로고
    • Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis
    • Binetruy-Tournaire R, Demangel C, Malavaud B, et al. Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis. EMBO J. 2000;19:1525-1533.
    • (2000) EMBO J , vol.19 , pp. 1525-1533
    • Binetruy-Tournaire, R.1    Demangel, C.2    Malavaud, B.3
  • 71
    • 0037051655 scopus 로고    scopus 로고
    • Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics
    • Reiher FK, Volpert OV, Jimenez B, et al. Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics. Int J Cancer. 2002;98:682-689.
    • (2002) Int J Cancer , vol.98 , pp. 682-689
    • Reiher, F.K.1    Volpert, O.V.2    Jimenez, B.3
  • 72
    • 0028899525 scopus 로고
    • Phage libraries displaying cyclic peptides with different ring sizes: Ligand specificities of the RGD-directed integrins
    • Koivunen E, Wang B, Ruoslahti E. Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins. Biotechnology (N Y). 1995;13:265-270.
    • (1995) Biotechnology (N Y) , vol.13 , pp. 265-270
    • Koivunen, E.1    Wang, B.2    Ruoslahti, E.3
  • 73
    • 0035266184 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and tumor growth by SCH221153, a dual alpha(v)beta3 and alpha(v)beta5 integrin receptor antagonist
    • Kumar CC, Malkowski M, Yin Z, et al. Inhibition of angiogenesis and tumor growth by SCH221153, a dual alpha(v)beta3 and alpha(v)beta5 integrin receptor antagonist. Cancer Res. 2001;61:2232-2238.
    • (2001) Cancer Res , vol.61 , pp. 2232-2238
    • Kumar, C.C.1    Malkowski, M.2    Yin, Z.3
  • 74
    • 0033950895 scopus 로고    scopus 로고
    • Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis
    • Pasqualini R, Koivunen E, Kain R, et al. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res. 2000;60:722-727.
    • (2000) Cancer Res , vol.60 , pp. 722-727
    • Pasqualini, R.1    Koivunen, E.2    Kain, R.3
  • 75
    • 0032842567 scopus 로고    scopus 로고
    • Tumor targeting with a selective gelatinase inhibitor
    • Koivunen E, Arap W, Valtanen H, et al. Tumor targeting with a selective gelatinase inhibitor. Nat Biotechnol. 1999;17:768-774.
    • (1999) Nat Biotechnol , vol.17 , pp. 768-774
    • Koivunen, E.1    Arap, W.2    Valtanen, H.3
  • 76
    • 3042687629 scopus 로고    scopus 로고
    • Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells
    • Laakkonen P, Akerman ME, Biliran H, et al. Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells. Proc Natl Acad Sci USA. 2004;101:9381-9386.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9381-9386
    • Laakkonen, P.1    Akerman, M.E.2    Biliran, H.3
  • 77
    • 0036415073 scopus 로고    scopus 로고
    • Somatostatin analogs and radiopeptides in cancer therapy
    • Froidevaux S, Eberle AN. Somatostatin analogs and radiopeptides in cancer therapy. Biopolymers. 2002;66:161-183.
    • (2002) Biopolymers , vol.66 , pp. 161-183
    • Froidevaux, S.1    Eberle, A.N.2
  • 78
    • 0347364636 scopus 로고    scopus 로고
    • Inhibition of mutant p53 expression and growth of DMS-153 small cell lung carcinoma by antagonists of growth hormone-releasing hormone and bombesin
    • Kanashiro CA, Schally AV, Groot K, et al. Inhibition of mutant p53 expression and growth of DMS-153 small cell lung carcinoma by antagonists of growth hormone-releasing hormone and bombesin. Proc Natl Acad Sci USA. 2003;100:15836-15841.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15836-15841
    • Kanashiro, C.A.1    Schally, A.V.2    Groot, K.3
  • 79
    • 11344255673 scopus 로고    scopus 로고
    • Inhibitory effect of antagonists of bombesin and growth hormone-releasing hormone on orthotopic and intraosseous growth and invasiveness of PC-3 human prostate cancer in nude mice
    • Stangelberger A, Schally AV, Varga JL, et al. Inhibitory effect of antagonists of bombesin and growth hormone-releasing hormone on orthotopic and intraosseous growth and invasiveness of PC-3 human prostate cancer in nude mice. Clin Cancer Res. 2005;11:49-57.
    • (2005) Clin Cancer Res , vol.11 , pp. 49-57
    • Stangelberger, A.1    Schally, A.V.2    Varga, J.L.3
  • 80
    • 0033809968 scopus 로고    scopus 로고
    • Peptide analogs in the therapy of prostate cancer
    • Schally AV, Comaru-Schally AM, Plonowski A, et al. Peptide analogs in the therapy of prostate cancer. Prostate. 2000;45:158-166.
    • (2000) Prostate , vol.45 , pp. 158-166
    • Schally, A.V.1    Comaru-Schally, A.M.2    Plonowski, A.3
  • 81
    • 0346668331 scopus 로고    scopus 로고
    • Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif
    • Colombo G, Curnis F, De Mori GM, et al. Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif. J Biol Chem. 2002;277:47891-47897.
    • (2002) J Biol Chem , vol.277 , pp. 47891-47897
    • Colombo, G.1    Curnis, F.2    De Mori, G.M.3
  • 82
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • Arap W, Pasqualini R, Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science. 1998;279:377-380.
    • (1998) Science , vol.279 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 83
    • 0035866780 scopus 로고    scopus 로고
    • RGD-Tachyplesin inhibits tumor growth
    • Chen Y, Xu X, Hong S, et al. RGD-Tachyplesin inhibits tumor growth. Cancer Res. 2001;61:2434-2438.
    • (2001) Cancer Res , vol.61 , pp. 2434-2438
    • Chen, Y.1    Xu, X.2    Hong, S.3
  • 84
    • 0032819838 scopus 로고    scopus 로고
    • Anti-cancer activity of targeted pro-apoptotic peptides
    • Ellerby HM, Arap W, Ellerby LM, et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 1999;5:1032-1038.
    • (1999) Nat Med , vol.5 , pp. 1032-1038
    • Ellerby, H.M.1    Arap, W.2    Ellerby, L.M.3
  • 85
    • 0037870167 scopus 로고    scopus 로고
    • Radiolabelled peptides for tumour therapy: Current status and future directions. Plenary lecture at the EANM 2002
    • de Jong M, Kwekkeboom D, Valkema R, Krenning EP. Radiolabelled peptides for tumour therapy: current status and future directions. Plenary lecture at the EANM 2002. Eur J Nucl Med Mol Imaging. 2003;30:463-469.
    • (2003) Eur J Nucl Med Mol Imaging , vol.30 , pp. 463-469
    • de Jong, M.1    Kwekkeboom, D.2    Valkema, R.3    Krenning, E.P.4
  • 86
    • 2542485272 scopus 로고    scopus 로고
    • Detection of colon cancer with 99mTc-labeled bombesin derivative (99mTc-leu13-BN1)
    • Scopinaro F, De Vincentis G, Corazziari E, et al. Detection of colon cancer with 99mTc-labeled bombesin derivative (99mTc-leu13-BN1). Cancer Biother Radiopharm. 2004;19:245-252.
    • (2004) Cancer Biother Radiopharm , vol.19 , pp. 245-252
    • Scopinaro, F.1    De Vincentis, G.2    Corazziari, E.3
  • 87
    • 2542506187 scopus 로고    scopus 로고
    • Gastrin-releasing peptide (GRP) analogues for cancer imaging
    • Varvarigou A, Bouziotis P, Zikos C, et al. Gastrin-releasing peptide (GRP) analogues for cancer imaging. Cancer Biother Radiopharm. 2004;19:219-229.
    • (2004) Cancer Biother Radiopharm , vol.19 , pp. 219-229
    • Varvarigou, A.1    Bouziotis, P.2    Zikos, C.3
  • 88
    • 0037432496 scopus 로고    scopus 로고
    • New approaches to treatment of various cancers based on cytotoxic analogs of LHRH, somatostatin and bombesin
    • Schally AV, Nagy A. New approaches to treatment of various cancers based on cytotoxic analogs of LHRH, somatostatin and bombesin. Life Sci. 2003;72:2305-2320.
    • (2003) Life Sci , vol.72 , pp. 2305-2320
    • Schally, A.V.1    Nagy, A.2
  • 89
    • 4444274816 scopus 로고    scopus 로고
    • Chemotherapy targeted to cancers through tumoral hormone receptors
    • Schally AV, Nagy A. Chemotherapy targeted to cancers through tumoral hormone receptors. Trends Endocrinol Metab. 2004;15:300-310.
    • (2004) Trends Endocrinol Metab , vol.15 , pp. 300-310
    • Schally, A.V.1    Nagy, A.2
  • 90
    • 0043233155 scopus 로고    scopus 로고
    • Human prostate cancer cells and xenografts are targeted and destroyed through luteinizing hormone releasing hormone receptors
    • Leuschner C, Enright FM, Gawronska-Kozak B, Hansel W. Human prostate cancer cells and xenografts are targeted and destroyed through luteinizing hormone releasing hormone receptors. Prostate. 2003;56:239-249.
    • (2003) Prostate , vol.56 , pp. 239-249
    • Leuschner, C.1    Enright, F.M.2    Gawronska-Kozak, B.3    Hansel, W.4
  • 91
    • 0036229112 scopus 로고    scopus 로고
    • Effects of a lytic peptide conjugated to beta HCG on ovarian cancer: Studies in vitro and in vivo
    • Gawronska B, Leuschner C, Enright FM, Hansel W. Effects of a lytic peptide conjugated to beta HCG on ovarian cancer: studies in vitro and in vivo. Gynecol Oncol. 2002;85:45-52.
    • (2002) Gynecol Oncol , vol.85 , pp. 45-52
    • Gawronska, B.1    Leuschner, C.2    Enright, F.M.3    Hansel, W.4
  • 92
    • 0033764170 scopus 로고    scopus 로고
    • Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
    • Curnis F, Sacchi A, Borgna L, et al. Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13). Nat Biotechnol. 2000;18:1185-1190.
    • (2000) Nat Biotechnol , vol.18 , pp. 1185-1190
    • Curnis, F.1    Sacchi, A.2    Borgna, L.3
  • 93
    • 0020363575 scopus 로고
    • SMS 201-995: A very potent and selective octapeptide analogue of somatostatin with prolonged action
    • Bauer W, Briner U, Doepfner W, et al. SMS 201-995: a very potent and selective octapeptide analogue of somatostatin with prolonged action. Life Sci. 1982;31:1133-1140.
    • (1982) Life Sci , vol.31 , pp. 1133-1140
    • Bauer, W.1    Briner, U.2    Doepfner, W.3
  • 94
    • 0042854927 scopus 로고    scopus 로고
    • Peptide receptors as molecular targets for cancer diagnosis and therapy
    • Reubi JC. Peptide receptors as molecular targets for cancer diagnosis and therapy. Endocr Rev. 2003;24:389-427.
    • (2003) Endocr Rev , vol.24 , pp. 389-427
    • Reubi, J.C.1
  • 95
    • 0036412478 scopus 로고    scopus 로고
    • Interactions of antimitotic peptides and depsipeptides with tubulin
    • Hamel E. Interactions of antimitotic peptides and depsipeptides with tubulin. Biopolymers. 2002;66:142-160.
    • (2002) Biopolymers , vol.66 , pp. 142-160
    • Hamel, E.1
  • 96
    • 0037316411 scopus 로고    scopus 로고
    • Phase 2 study of cryptophycin 52 (LY355703) in patients previously treated with platinum based chemotherapy for advanced non-small cell lung cancer
    • Edelman MJ, Gandara DR, Hausner P, et al. Phase 2 study of cryptophycin 52 (LY355703) in patients previously treated with platinum based chemotherapy for advanced non-small cell lung cancer. Lung Cancer. 2003;39:197-199.
    • (2003) Lung Cancer , vol.39 , pp. 197-199
    • Edelman, M.J.1    Gandara, D.R.2    Hausner, P.3
  • 97
    • 10744230054 scopus 로고    scopus 로고
    • A phase II study of the dolastatin 15 analogue LU 103793 in the treatment of advanced non-small-cell lung cancer
    • Marks RS, Graham DL, Sloan JA, et al. A phase II study of the dolastatin 15 analogue LU 103793 in the treatment of advanced non-small-cell lung cancer. Am J Clin Oncol. 2003;26:336-337.
    • (2003) Am J Clin Oncol , vol.26 , pp. 336-337
    • Marks, R.S.1    Graham, D.L.2    Sloan, J.A.3
  • 98
    • 9744243565 scopus 로고    scopus 로고
    • Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates
    • Law CL, Cerveny CG, Gordon KA, et al. Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates. Clin Cancer Res. 2004;10:7842-7851.
    • (2004) Clin Cancer Res , vol.10 , pp. 7842-7851
    • Law, C.L.1    Cerveny, C.G.2    Gordon, K.A.3
  • 99
    • 10744222473 scopus 로고    scopus 로고
    • Development of potent monoclonal antibody auristatin conjugates for cancer therapy
    • Doronina SO, Toki BE, Torgov MY, et al. Development of potent monoclonal antibody auristatin conjugates for cancer therapy. Nat Biotechnol. 2003;21:778-784.
    • (2003) Nat Biotechnol , vol.21 , pp. 778-784
    • Doronina, S.O.1    Toki, B.E.2    Torgov, M.Y.3
  • 100
    • 0042738861 scopus 로고    scopus 로고
    • cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity
    • Francisco JA, Cerveny CG, Meyer DL, et al. cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity. Blood. 2003;102:1458-1465.
    • (2003) Blood , vol.102 , pp. 1458-1465
    • Francisco, J.A.1    Cerveny, C.G.2    Meyer, D.L.3
  • 101
    • 0141919559 scopus 로고    scopus 로고
    • E-selectin up-regulation allows for targeted drug delivery in prostate cancer
    • Bhaskar V, Law DA, Ibsen E, et al. E-selectin up-regulation allows for targeted drug delivery in prostate cancer. Cancer Res. 2003;63:6387-6394.
    • (2003) Cancer Res , vol.63 , pp. 6387-6394
    • Bhaskar, V.1    Law, D.A.2    Ibsen, E.3
  • 102
    • 4444297534 scopus 로고    scopus 로고
    • Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer
    • Afar DE, Bhaskar V, Ibsen E, et al. Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer. Mol Cancer Ther. 2004;3:921-932.
    • (2004) Mol Cancer Ther , vol.3 , pp. 921-932
    • Afar, D.E.1    Bhaskar, V.2    Ibsen, E.3
  • 103
    • 1942535110 scopus 로고    scopus 로고
    • Folate receptor-targeted drugs for cancer and inflammatory diseases
    • Low PS, Antony AC. Folate receptor-targeted drugs for cancer and inflammatory diseases. Adv Drug Deliv Rev. 2004;56:1055-1058.
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1055-1058
    • Low, P.S.1    Antony, A.C.2
  • 104
    • 9444279605 scopus 로고    scopus 로고
    • Ligand binding and kinetics of folate receptor recycling in vivo: Impact on receptor-mediated drug delivery
    • Paulos CM, Reddy JA, Leamon CP, et al. Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery. Mol Pharmacol. 2004;66: 1406-1414.
    • (2004) Mol Pharmacol , vol.66 , pp. 1406-1414
    • Paulos, C.M.1    Reddy, J.A.2    Leamon, C.P.3
  • 105
    • 23244454577 scopus 로고    scopus 로고
    • Folate receptor-targeted immunotherapy: Induction of humoral and cellular immunity against hapten-decorated cancer cells
    • Lu Y, Sega E, Low PS. Folate receptor-targeted immunotherapy: induction of humoral and cellular immunity against hapten-decorated cancer cells. Int J Cancer. 2005;116:710-719.
    • (2005) Int J Cancer , vol.116 , pp. 710-719
    • Lu, Y.1    Sega, E.2    Low, P.S.3
  • 106
    • 0031742801 scopus 로고    scopus 로고
    • In vivo fate of folate-BSA in non-tumor- and tumor-bearing mice
    • Shinoda T, Takagi A, Maeda A, et al. In vivo fate of folate-BSA in non-tumor- and tumor-bearing mice. J Pharm Sci. 1998;87: 1521-1526.
    • (1998) J Pharm Sci , vol.87 , pp. 1521-1526
    • Shinoda, T.1    Takagi, A.2    Maeda, A.3
  • 107
    • 0034128393 scopus 로고    scopus 로고
    • Folic acid targeting of protein conjugates into ascites tumour cells from ovarian cancer patients
    • Ward CM, Acheson N, Seymour LW. Folic acid targeting of protein conjugates into ascites tumour cells from ovarian cancer patients. J Drug Target. 2000;8:119-123.
    • (2000) J Drug Target , vol.8 , pp. 119-123
    • Ward, C.M.1    Acheson, N.2    Seymour, L.W.3
  • 109
    • 0348223342 scopus 로고    scopus 로고
    • Optical imaging of metastatic tumors using a folate-targeted fluorescent probe
    • Kennedy MD, Jallad KN, Thompson DH, et al. Optical imaging of metastatic tumors using a folate-targeted fluorescent probe. J Biomed Opt. 2003;8:636-641.
    • (2003) J Biomed Opt , vol.8 , pp. 636-641
    • Kennedy, M.D.1    Jallad, K.N.2    Thompson, D.H.3
  • 110
    • 0036219732 scopus 로고    scopus 로고
    • Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors
    • Lu Y, Low PS. Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors. Cancer Immunol Immunother. 2002;51:153-162.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 153-162
    • Lu, Y.1    Low, P.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.